Podcasts by Category
Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated. Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
- 723 - Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.6. 17April 2024.Authentic Biochemistry Podcast.Dr. Daniel J. Guerra.
References
Cold Spring Harb Perspect Med. 2020 Jun; 10(6): a034819
Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28): 8661–8666
Blood. 2010 Jul 22; 116(3): 485–494.
Haydn, FJ. 1793. Symphony No 101 D major "Die Uhr“.
https://youtu.be/jK9EPZ3qdgU?si=GiCVxNOchDW0fKsb
Croce, J. 1970. "Time in a Bottle".
https://youtu.be/9h1davKgBYM?si=YhyPwAtno04oYBks
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 17 Apr 2024 - 30min - 722 - T lymphocyte Membrane Biochemistry I. Immune Cell Biochemistry I c.5 Authentic Biochemistry 16April2024 Dr Daniel J. Guerra
References
Front. Immunol., 2022 Sec. Microbial Immunology Volume 12
Blood 2010. Volume 115, Issue 18, 6 May: 3708-3717
Seeger, P. 1959 . Performed by The Byrds "Turn Turn Turn"
https://youtu.be/W4ga_M5Zdn4?si=ODKk_snS-5XHZvWP
Copland, A. 1944. "Appalachian Spring.
https://youtu.be/CJYVH_kZkOk?si=UUBet58ETg0PVUrB
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 17 Apr 2024 - 29min - 721 - Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.4. 15April 2024. Chemokine gradients and the membrane lipid raft. Authentic Biochemistry Podcast Dr. Daniel J. Guerra
References
FEBS J. 2018 Aug; 285(16): 2944–2971.
Nature Reviews Immunology 2023.volume 23, pages 236–250.
Angiogenesis. 2021; 24(4): 719–753.
Front. Immunol. 2022 Sec. Microbial Immunology Volume 12
Camp, H. 1964. "Pride of Man". performed by Quicksilver Messenger Service.
https://youtu.be/fG6A6G9uzsQ?si=tKMdQMVbpTn2x85D
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportTue, 16 Apr 2024 - 29min - 720 - Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.3. 14 April 2024 .Authentic Biochemistry Podcast.Dr. Daniel J. Guerra
References
Nat Rev Gastroenterol Hepatol. 2022 Jun;19(6):351-366
Drugs. 2016 Jul;76(11):1067-79.
Front Immunol. 2021; 12: 613591
J Appl Microbiol. 2009. Jun;106(6):1908-18
Exp Cell Res. 2015 May 1; 333(2): 195–200.
Mediators Inflamm. 2017; 2017: 4806541.
Parsons, G. McQuinn,R. 1971. Pale Blue [ Byrds] Byrdmaniax lp. https://youtu.be/Mh3J7GqrdzY?si=Kp0XfrwPtSi4vY6q
Baker, G. 1967. "Blue Condition" [Cream]. Disraeli Gears lp.
https://youtu.be/bjQjEyJwPpg?si=70Nye1AGPWsgG0hs
Strauss, J.(II). 1866 "An der schönen blauen Donau", Op. 314
https://youtu.be/fHzhDKwYP2s?si=umxkaYC6nRvikezX
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 15 Apr 2024 - 29min - 719 - Immune Cell Biochemistry I.T lymphocyte Membrane Biochemistry c.2 Lipid mespmorph and radius assymetry direct Tcell membrane sterol and protein interdigitation that is altered by pressure via PV=nRT.
References and simple equations
PV = nRT where P is pressure (in atm), V is volume (in liters), n is number of moles and T is temperature (in K); R is a constant and is equal to 0.08206 L atm/moleK.
Molecular Shape including thickness(radius) of membrane curvature is v/al where v=volume,a=area per headgroup, and l=thickness of the hydrocarbon monolayer
Guerra, D. Membrane Biochemistry notes
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 13 Apr 2024 - 30min - 718 - Immune Cell Biochemistry I.T lymphocyte Membrane Biochemistry c.1. DJGPhD.11April24.Authentic Biochemistry Podcast
References
Front Immunol . 2021 Mar 10:12:613591.
Guerra, D. 2020's. Membrane Biochemistry Lectures
Crosby, D., Kantner, P., and Stills, S. 1968. "Wooden Ships" [Jefferson Airplane ] from Volunteers lp.
https://youtu.be/ROBaoiJK0wc?si=ABsxa4m4AjjAwoms
Mendelsshon, F. 1830. "The Hebrides Overture"-Fingal's Cave.OP26.
https://youtu.be/MdQyN7MYSN8?si=w9G1d0_5DFJn-tzx
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 12 Apr 2024 - 29min - 717 - Biochemical Mosaic III. Coda. DJGPhD .09April24.Authentic Biochemistry Podcast
References
Guerra, D. 2024. The Mosaics I-III.
https://podcasts.apple.com/us/podcast/authentic-biochemistry/id1454408625
Beethoven, LV. 1806. Violin Concerto D Major. Op 61.
https://youtu.be/cokCgWPRZPg?si=pKKUsINChgI14PH9
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 10 Apr 2024 - 30min - 716 - Biochemical Mosaic III. c.14. From physical chemistry to the mechanisms of sphingomyelinase mediated inflammation: abrief dialectical accounting of research involving abiotic vs biological phenomena.
References
Guerra, D. 2024. Previous Lectures: Authentic Biochemistry.
https://podcasts.apple.com/us/podcast/authentic-biochemistry/id1454408625
Waters, R.1973. "Eclipse" from [Dark Side of the Moon]; Pink Floyd lp.
https://youtu.be/k0xGxnZFNYs?si=VrfYPQuXef41Drfm
Holst, G. 1918. "The Planets"
https://youtu.be/HP5xhyPn58U?si=IdN_iqJNvt_tjQKP
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 08 Apr 2024 - 30min - 715 - Biochemical Mosaic III.c.13. A priori intralocution of inflammasome genomic loci with stress phenomena immunoepigenetically resolves defensive inflammation. DJGPhD.6April24. Authentic Biochemistry.
References
Guerra, D. 2024 Previous Mosaic III lectures and content.
https://podcasts.apple.com/us/podcast/authentic-biochemistry/id1454408625
Hayward, J. 1969. "Never Comes the Day" from Moody Blues lp. Threshold of a Dream.
https://youtu.be/8u1zH11yqFQ?si=xtXp1SWm8rF1RdFS
Mozart, WA.1785. String Quartet No. 19 in C Major, K. 465
https://youtu.be/f3oK4XVMARs?si=FMypvP8O_WCII7vR
Page, J.1972. "The Rain Song" Led ZeppelinHouses of the Holy lp.
https://youtu.be/g8VduT7aR2c?si=zB2oS2kCV2t4WtEb
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSun, 07 Apr 2024 - 30min - 714 - Biochemical Mosaic III. c12. A prolegomena to any future biochemical Instanence. Dr Daniel J. Guerra. 4April2024. Authentic Biochemistry Podcast
Refernces
Guerra, DJ. Inclusive non-extemporaneous reasoning on biochemical event ontologies.
Jefferson, Blind Lemon 1927, Hunter-Garcia 1969 Jefferson's "I know You Rider" and "China Cat Sunflower" . Grateful Dead. Europe 72' LP.
https://youtu.be/xCgZxrf8nrU?si=k7WGmY-fo_AjEip-
Schmelzer, JH 1664. Violin Sonatas, "Romanesca".
https://youtu.be/fB8G39y1uCA?si=hzGCK2Qq6TtIubAh
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 05 Apr 2024 - 29min - 713 - Biochemical Mosaic III. Inflamasomes c.11 A Dialectical Event Ontological conciliantus contrarion perspective.DJGPhD.3April24.Authentic Biochemistry Podcast.
REferences
Guerra, DJ. 2024. Biochemical Mosaic III lectures.
https://podcasts.apple.com/us/podcast/authentic-biochemistry/id1454408625
Dvorak, A. 1879. Romance in F minor, Op. 11, (B. 39).
https://youtu.be/XZTeavJ9frA?si=18LFzAQ9FKfrQ_16
Dylan, R. 1975. "Tangled up in Blue" performed by Gerry Garcia Band (live;1977)
https://youtu.be/8Aw7FW1Frjs?si=jURQC3jBWFPirSh8
Betts, R. 1972. "Blue Sky" Allman Brothers (Eat a Peach.lp.)
https://youtu.be/wwyXQn9g40I?si=15Cv6iJxR82VAb_3
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 04 Apr 2024 - 29min - 712 - Biochemical Mosaic III.c.10 Atherogenesis and neointma formation are associated with sphingomyelinase membrane raft NOX aggregation during inflammasome activation.DJGPhD.2April24
References
J Lipid Res. 2022 Dec; 63(12): 100298.
Mol Cells. 2020 Aug 31; 43(8): 749–762.
Bach J.S. 1727. St Matthew Passion, BWV 244.
https://www.youtube.com/live/3fP-rET0kFI?si=ZX-edMPg1wBA_5mh
Squire, Chris. 1978. "You Can Be Saved" Yes.
https://youtu.be/0TNzPHoVlz8?si=bFMp6w4T2SL6XxS4
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 03 Apr 2024 - 29min - 711 - Biochemical Mosaic III.c.9 Clinical associations of inflammasome mediated pathophysiology linked to epigenetic methylation patterning and DNA repair. DJGPhD.1April24.
References
Redox Biol. 2020 Apr; 31: 101482
Nat Rev Microbiol. 2009 Feb; 7(2): 99–109.
J Neuroinflammation. 2019; 16: 236.
Front Pharmacol. 2021; 12: 643254.
Biber, H. 1676. "Passagalia" por solo violin
https://youtu.be/sgcR183f8gA?si=ovfSbdg6WsfuIiTw
McBroom, A. 1976. "The Rose" Conway Twitty
https://youtu.be/cO59ITNCxzk?si=ueMmXtzMNH4YeQ_w
Hunter-Weir. 1970. "Sugar Magnolia" American Beauty L.P.
https://youtu.be/ei5EmN2HmVI?si=6ZrBBPmu3cMyMOAO
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportTue, 02 Apr 2024 - 30min - 710 - Biochemical Mosaic III.c.8. S. aureus clearance via dual pyroptosis and necroptosis salientsand the control over the hyperinflammatory axis of clinical disease. DJGPhD.31.3.24
References
Cell Reports 2016.Volume 16, Issue 8, 23 Pages 2219-2230
Front Immunol. 2020; 11: 621733
Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E961-E969
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 01 Apr 2024 - 29min - 709 - Biochemical Mosaic III.c.7 Convergence of Inflammasome molecular patterning obtains PRR-like sequalae that are hypo-modified epigenetically in multple Human pathophysiologies
References
Int J Mol Sci. 2021 Jul; 22(14): 7580.
Trends Biochem Sci. 2023 Apr;48(4):331-344
Immunology. 2020;159:142–155
Curr. Opin. Immunol. 2020;62:39–44.
Nat. Rev. Mol. Cell Biol. 2019;20:569–570.
Lennon-McCartney. 1963. "This Boy"
https://youtu.be/lW5D7HpYhBU?si=mHyiFng3rd3pukob
Lennon-McCartney.1966. "And your Bird Can Sing"
https://youtu.be/sOUlbredoUM?si=nPB64c8GS4joYx9G
Lennon-McCartney 1969. "Let it Be"
https://youtu.be/QDYfEBY9NM4?si=H6t6bwrv3vUNWoDj
Vivaldi, A. 1715 "Gloria"
https://youtu.be/RMHguvZPcqQ?si=igPXLKL9O0YbRWKz
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 28 Mar 2024 - 30min - 708 - Biochemical Mosaic III. c.6. S auereus induced inflammasome activating pyroptosis circumvents immune clearance and ARDS pulmonary chronic activation share similar hyperinflammatory presentation.DJGPhD
References
Front Immunol. 2019; 10: 1309
Immunity. 2018 Sep 18; 49(3):413–426.e5.
Front Immunol. 2020; 11: 621733
Infect Immun. 2013 Dec; 81(12): 4478–4489.
Immunity. 2023 Nov 14;56(11):2523-2541.e8.
Harrison, G. 1969. "Here Comes the Sun" Abbey Road Lp. Beatles
https://youtu.be/GKdl-GCsNJ0?si=xUqwi3Q7Ne694ruD
Mozart, WA. 1775. Violin Concerto No.3 in G major, K. 216
https://youtu.be/j7Z6gouAVCc?si=xVwtNKAWDEDdtKMV
Parsons, G. 1965 "Brass Buttons" Poco: Crazy Eyes Lp.
https://youtu.be/CpFytplzLhI?si=vw08Gut3E-otgA9x
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 27 Mar 2024 - 30min - 707 - Biochemical Mosaic III. c.5. Gal3 and NRLP3 inflammasome coordinate inflammation via IL-1Beta convertase activation that is associated with NAFLD and NASH and inhibition of ABCA1 cholesterol efflux.
References
Infect Immun. 2013 Dec; 81(12): 4478–4489
Cell Cycle. 2022; 21(11): 1121–1139.
The Journal of Nutritional Biochem.2023.Volume 112, 109217
Lightfoot, G. 1964. "Early Morning Rain"
https://youtu.be/ZFJ5Bj_put0?si=m1Ue7rFfk_ggSLR3
Simon ,P. 1968. "Old Friends" SImon and Garfunkle Bookends LP.
https://youtu.be/7A76lTte8qE?si=rfk3Q6wTA6Nsiok7
Mozart, WA. 1782 Serenade in C. Minor K.388.
https://youtu.be/R6iSGBNdqSw?si=S2eGPmcySUhw4uvU
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 25 Mar 2024 - 29min - 706 - Biochemical MosaicIII. C.4. My oppositional dialectic and episteme- metaphysical discourse on method+ Gal3 as proinflammatory lectin may not uniformly correlate with pathobiochemical events. DJGPhD.
References
Guerra, DJ. 2024. Uncollected writings.
The Journal of Nutritional Biochemistry 2023. Volume 112, February. 109217
Walker, Cindy.1950 Blue Canadian Rockies. Cover "the Byrds"(1969).
https://youtu.be/nzOHtU8Sb3c?si=5GAj7VPzIr7o0OO_t
Heinichen J. D. 1711 (?)Concerto in A minor for violin
https://youtu.be/V-E25Q-wjwc?si=bbWdZTNEUPGitY-S
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 23 Mar 2024 - 30min - 705 - Biochemical Mosaic III c.3. Bacterial glycosphingolipid mediated inflammasome activation and the Galectin:NLRP3 interaction pathophenocopy oxy-mtDNA TLR induction.DJGPhD.21.3.24
References
Front Immunol. 2020; 11: 591803
Am J Gastroenterol. 2004 Nov;99(11):2147-9.
Biochem Biophys Res Commun. 2005 Dec 16;338(2):1031-6
Front Immunol. 2019 Jun 7;10:1309.
FASEB J. 2021 May; 35(5): e21439.
Hildegard von Bingen 1150.- "Canticles Of Ecstasy
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 22 Mar 2024 - 28min - 704 - Biochemical Mosaic III. C.2 A Non-canonical autophagic inhibition of NLRP3 inflammasome mediated inflammation in UVB-treated human keratinocytes.DJGPhD. 20.3.24.
References
Front Immunol. 2019 Jun 7;10:1309.
JBC 2024 . March.Article in Press
DOI:https://doi.org/10.1016/j.jbc.2024.107173FASEB J. 2016 Dec;30(12):4202-4213.
Nat Rev Gastroenterol Hepatol . 2020 Feb;17(2):93-110
Bach , JS. 1731. Piano Partita No. 2 In C Minor, BWV 826
https://youtu.be/f-OdOuNZciQ?si=AmFtC5CX3x2ndzdV
Slade,Mann, and Rogers. 1975 "Time is Right" Manfred Mann
https://youtu.be/jzJIej8h5q4?si=3-aCFe0tqur4lfX1
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 21 Mar 2024 - 30min - 703 - Biochemical Mosaic III. C.1. Inflammasomes. DJGPhD.19.3.24 Authentic Biochemistry Podcast
References
Immunity 2022. Volume 55 Issue 8 Pages 1370-1385.e8
JBC 2024. March. Article in Press
https://doi.org/10.1016/j.jbc.2024.107173
Schmelzer. J. H.1664 Sonatae unarum fidium.
https://youtu.be/fB8G39y1uCA?si=ZMG2Zv9eKF3go0qR
Hayward, J. 1967 "Tuesday Afternoon" Moody Blues
https://youtu.be/fB8G39y1uCA?si=ZMG2Zv9eKF3go0qR
Hayward, J. 1970 "Question" Moody Blues
https://youtu.be/NP9iOqdxS8c?si=rfI3lzy0HhcffkWT
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 20 Mar 2024 - 30min - 702 - Biochemical MosaicII.Book2.C.13.Dialectical event ontologies involving CNS plasmalogen and sphingolipid interlocution and the universality of Mozart and the Beatles. DJGPhD.17.3.24.Authentic Biochem.
REferences
Dr. Guerra. 2024.Previous Authentic Biochemistry Mosaic II lectures in the series
Kant, I. 1790. Critique of Judgment.
Mozart, WA. 1788. Sinfonie C-Dur KV 551 (»Jupiter«)
https://youtu.be/6RbKWhr0o1c?si=xkt3QMG5aud__zLN
Beatles. 1965. "Rubber Soul"
https://youtu.be/kfSQkZuIx84?si=8QFvenLD4k8KLJD3
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 18 Mar 2024 - 30min - 701 - Biochemical Mosaic II.Book 2. c.12 Adduced mTORC mediated glycerol-sphingolipid enzyme mRNA transcriptome association with Plasmalogen apodiction of myelination.DJGPhD.16.3.24
References
Developmental Cell 2022. Volume 57, Issue 6, 28 March Pages 691-706
Cell Rep. 2014 Feb 13; 6(3): 541–552.
Dr Guerra: graduate lecture notes
Mozart, WA 1791.Requiemin D Minor, K 626
https://youtu.be/YaH3zI0bYkM?si=X1yv50zY6nKTZmV9
Lennon/McCartney.1964 "I Don't Want to Spoil the Party"
https://youtu.be/zqVDvLDLsjI?si=K1ve_5zJLZjqclsb
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSun, 17 Mar 2024 - 29min - 700 - MosaicII,Bk.2.c.11 Squalene monooxygenase (SM) stabilization due to plasmalogen pathway fatty acid reductase deficiency promotes SM epoxidase alternate activity thus lowering24OHCHOL-LXR-myelination.
References
Dr Guerra-Graduate lipid biochemistry lectures
Biochem J. 2022 Sep 30; 479(18): 1917–1940
Front Cell Dev Biol. 2022; 10: 946393.
Nat Commun. 2019; 10: 97.
Lennon-McCartney 1965. "Ive Just Seen a Face"
https://youtu.be/m8LbJfC0SYM?si=gl_URu_yPTn9iZSd
McShee, J./Traditional/Pentangle.1969 "Light Flight"
https://youtu.be/2tyVezuUtCA?si=THxBJ0reUETkwDLa
Mozart, WA. 1785.Piano Concerto No. 21 in C Major, K. 467
https://youtu.be/whTEVQ2OizI?si=YDMhOhlwmpKYqK-t
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 14 Mar 2024 - 29min - 699 - Biochemical Mosaic II. Book2. c.10.Plasmalogen mediated oxy vs epoxy sterol synthesis may control cns inflammation and myelination given acid-catalyzed transacetalization sequalae.DJGPhD.12March24
References
Front Cell Dev Biol. 2022; 10: 946393.
Adv Exp Med Biol. 2024:1440:149-161
Mozart, WA..1786.Horn Concerto in E-flat major # 4 KV 495
https://youtu.be/MMjqU461WpI?si=o2OWIijoe-mbF-pM
Sebastian, J. 1968 She's a Lady
https://youtu.be/xyFdzevDOHg?si=wgmv5z_jGrtA9x7c
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 13 Mar 2024 - 29min - 698 - Biochemical Mosaic II. Book2. c.9. Plasmalogen regulation of composite ruling over prescriptive organization of cellular-biochemical phenomena includes florid mediation of the CNS.DJGPhD.11MARCH2024.
References
Journal of Cell Science 2019.Vol.132(6), 223016.
Brain Research Bulletin 2023.Volume 194, March. Pages 118-123.
Beethoven, LV. 1806. Violin Concerto D major, Op. 61
https://youtu.be/_hXdjRYELGw?si=0q5_qJCZu_zAZWoE
Berry, C. 1956. "Roll Over Beethoven" ; as performed by the Beatles 1963 on LP "With the Beatles"
https://youtu.be/Hz5jXwOXgKQ?si=FASk6PG2SAsEkrvP
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportTue, 12 Mar 2024 - 29min - 697 - Biochemical Mosaic II.c.8 Cell death and CE-circ RNA vs.miRNA in Hepatocellular carcinoma: the spectre of AGPS et al. DJGPhD. 10March24.Authentic Biochemistry.
References
Cell Death Dis. 2020 Dec; 11(12): 1065.
Genome Res. 2000 Oct; 10(10): 1445–1452.
https://www.genecards.org/cgi-bin/carddisp.pl?gene=NIPBL
Genes Dis. 2022 Jan; 9(1): 116–127
Schubert, F. 1824. Quartet 14in D minor, D 810, "Death and the Maiden"
https://youtu.be/XF_6vSlmm4w?si=CGTn3R6Tkn6LsMLv
Browne,J. 1993. "Sky Blue and Black".
https://youtu.be/Ty1I6dtC2zc?si=QHuwDiQUDh-4S5VP
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 11 Mar 2024 - 29min - 696 - Biochemical Mosaic II.c.7. Fatty acid desaturation and mole% PC/PE/PL/CER are elevated via circRNA in Medublastoma while AGPS increased circRNA's in thyroid cancer.DJGPhD.7Mar24. Authentic Biochem.
References
Acta Neuropathologica Communications 2023. volume 11, Article number: 38
Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7792–7798
Front Mol Biosci. 2022; 9: 925389.
Front Cell Dev Biol. 2021; 9: 636838
Oncol Lett 2018. 15: 7889-7899.
Saint-Saëns, C. 1886. Symphony No 3 in C minor, Op 78
https://youtu.be/ZWCZq33BrOo?si=8hQ01E9jfp0eU07o
Winwood,S. 1969. Had to Cry Today (Blind Faith)
https://youtu.be/Z4Yo_VbGdMg?si=tWz0_qnG5Nsx5qxX
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 08 Mar 2024 - 29min - 695 - Biochemical Mosaic II.c.6 Meduloblastoma is linked to plasmalogen and circ RNA phenomena that are pathophenocopied in other cancers. DJGPhD.5.Mar24.Authentic Biochemistry
References
Acta Neuropathologica Communications2023. volume 11, Article number: 38
Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7792–7798.
Int J Med Sci. 2022; 19(6): 975–985
Nature Communications2022. volume 13, Article number: 1508
Lassus. O. 1578. Requiem - Missa pro defunctis (4vv) : Offertorium
https://youtu.be/UXY4hxCvu7M?si=lcM_lw11lbPWrYX4
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 06 Mar 2024 - 30min - 694 - Biochemical Mosaic II. c.5 Peroxisomal plasmalogen biosynthesis may regulate transcriptomic and proteomic sequalae to plasmamembrane mediated signal transduction. DJGPhD.4March24.
References
Front Physiol. 2021; 12: 730829.
Non-coding RNA Investig 2017. 1:5.
Genome Biology2011. volume 12, Article number: 236
RNA Biol . 2021 Nov 12;18(sup2):574-585.
Hunter. R. 1975. "Cruel White Water"
https://youtu.be/T-oBD3F74Nk?si=zsrEBN0JKan_FXdH
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 04 Mar 2024 - 30min - 693 - Biochemical Mosaic II. c.4. Peroxisomal biogenesis and AGPS-mediated plasmalogen synthesis involve circular RNA species that alter microRNA and mRNA expression in human cancers. DJGPhD.3MAR24.
References
Genome Res. 2004 Nov;14(11): 2245–2252.
Int J Med Sci. 2022; 19(6): 975–985.
Oncol Lett. 2018 May; 15(5): 7889–7899.
Cell Death Dis. 2020 Dec; 11(12): 1065.
RNA Biol . 2021 Nov 12;18(sup2):574-585
Bach, J Christian. 1775. Sinfonie Concertante
https://youtu.be/S8NPgouJ5uk?si=_azSWNelNFRA2ai5
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 04 Mar 2024 - 29min - 692 - Saturday Night Authentic Biochemistry The Agentic operator as metaphysical metaphor in metabolic regulation. DJGPhD.2March 2024.
References
Dr Guerra Archives: Graduate Biochemistry Lecture notes and syntheses
Simon, P. 1969. The Boxer.
https://youtu.be/l3LFML_pxlY?si=Nv5-mSzRu6fHP8Sr
Boccherini, L. 1760. 7. Cellokonzert
https://youtu.be/NSU6Ylxaobs?si=PZW0S3mWl25RwnE2
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSun, 03 Mar 2024 - 30min - 691 - Biochemical Mosaic II. c.3 Plasmalogen metabolism is coherently associated with peroxisomal integrity and replication. DJGPhD.01March 2024 Authentic Biochemistry.
References
Oncol Lett. 2018 May; 15(5): 7889–7899
Nat Genet. 1997 Apr;15(4):369-76
Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118609
Protein Cell 2018. 9, 196–206
Brain Research Bulletin 2023. 194: 118–123
The Moody Blues. 1968. "In Search of the Lost Chord"
https://youtu.be/k5UdP-SFNgY?si=zDboUgA2LDi3E7m1
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 02 Mar 2024 - 30min - 690 - Biochemical Mosaic II. C.2. Plasmalogen and PAF biosynthesis in relation to glycerol lipid and intermediary subcellular metabolism.DJGPhD.27.2.24
References
Guerra: graduate biochemistry lectures
Chopin, F. 1830. Nocturne E Flat Major Op.9 No.2
https://youtu.be/tV5U8kVYS88?si=MKxfguVRI6hhQeMO
Winwood, Wood and Capaldi 1967. Dear Mr Fantasy. Traffic.
https://youtu.be/sS_eHdqcrM8?si=95X9RWJD2Q4w456S
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 28 Feb 2024 - 29min - 689 - Biochemical Mosaic II. Plasmalogens & other ether lipids. c.1 DJGPhD.26.2.24. Authentic Biochemistry Podcast
References
Cell Metab. 2014 Mar 4; 19(3): 380–392.
Protein Cell 2018. 9, 196–206.
Membranes 2023, 13(9), 764.
Debussy , C. (. 1890;1905) Clair de lune.
https://youtu.be/6zzWnxuQPWI?si=gcEAKpbgc9xO8esf
Morricone. E. 1968. "Once Upon a Time in the West"
https://youtu.be/j5eQ9UTmDLo?si=-eUjJ1s9hAd6fpwz
Schubert, F. 1825. Ave Maria
https://youtu.be/2H5rusicEnc?si=LcYisCODwtGgjjVx
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 26 Feb 2024 - 29min - 688 - A Dialectical Interlocution with Mozart. DJGPhD.24.2.24 Authentic Biochemistry Podcast
References
Mozart.WA
1782. Fantasie in D minor. K.397
https://youtu.be/OYiz_u0tDwM?si=0dP736rTEkb4sauL
1785.Piano Concerto 22 in E flat Major.K.482
https://youtu.be/EJYPnrYNt8A?si=VqgS-PNw2bnbIFBj
1788.Divertimento in E♭ major, K. 563.
https://youtu.be/2N4hHhTu4pw?si=p-VwHTTOK5ixFWfk
1787. Eine kleine Nachtmusik, K. 525.
https://youtu.be/156u4nV2uGE?si=bRqysFpbi-6j0jMk
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSun, 25 Feb 2024 - 28min - 687 - Biochemical Mosaic I. CODA. Membrane lipids function as biosensors for pKa's of phosphonoester anionic charge density with polybasic protein domains to mediate communication including transcription.
References
J Biol Chem 2017 292: 20481.
Nature Cell Biology2019. volume 21, pages 338–347
Rossini.G. 1829. William Tell Overture.
https://youtu.be/z7Tj2SzToHI?si=QUXkj3NzqF17Zq60
Vivaldi, A. 1712. Concerto in D Major. RV 212.
https://youtu.be/l21_9KKy1Pg?si=9HSMxRj7huJF1B8j
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 24 Feb 2024 - 29min - 686 - Biochemical MosaicI.c.13 Phosphatidic acid as key lipid intermediary of membrane secretion signalling and cellular intracommunication via kinase cascade and transcriptional regulation.DJGPhD.22.2.24
References
Biomedicines 2023, 11(7), 1804
BMC Biology. 2011. 9:85
Cancer Res. 2011 Jan 15;71(2):293-7.
FEBS Lett.2019.593.17:2428-2451
Verdi, G. 1841. Nabucco Overture
https://youtu.be/OseGETWEnCo?si=LhiIQV-N0-_Z_s-s
Lennon&McCartney. 1966 "For No One". Beatles: Revolver.
https://youtu.be/sep5E3ssXLQ?si=WLtMrP-Xq279qZXl
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 23 Feb 2024 - 29min - 685 - Biochemical Mosaic I. c.12. The porosomal secretory system requires anioic lipids including phosphatidic acid. DJGPhD.21.2.24
Dr. Guerra: membrane graduate biochemistry lecture notes
J Cell Mol Med . 2015 Jul;19(7):1427-40
Langmuir, 2018, 34 (1), pp 530–539
Elgar, E. 1900. The Dream of Gerontius
https://youtu.be/rnwmVypRY-g?si=CxF8tZrfRR-uWdhn
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 22 Feb 2024 - 29min - 684 - Biochemical Mosaic I.c.11. Glycerolipid metabolism coupled to mTORC1 enzyme phosphorylation necessarily involves a complete analysis of membrane lipid molecular species distribution.DJGPhD.20.2.24
References
Nature . 2019 Nov;575(7782):361-365.
Adv Biol Regul. 2017 May:64:39-48
J Biol Chem. 2013 Apr 5; 288(14): 9933–9945
Redox Biology.2017. Volume 11, April. Pages 622-630
Biochim Biophys Acta. 2011 Jun;1811(6):377-85
Dr Guerra: lipid lectures archives
Schubert, F. 1816. Symphony #5
https://youtu.be/OHkot1TmvZU?si=uYtQfxUegl3KrkRK
Newman, L Darby K. 1954. Marilyn Monroe. The River of No Return
https://youtu.be/dLzeHkEQe9g?si=nXMd20gstc3vVdgl
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportTue, 20 Feb 2024 - 29min - 683 - Biochemical Mosaic I c.10. Is PE depletion reversed by mTORC1 phosphorylation of LIPIN1 or is DAG authentically activating CCT via membrane association thus obtaining robust PL synthesis? DJGPhD.
References
Biochim Biophys Acta. 2011 Jun;1811(6):377-85
Am J Physiol Lung Cell Mol Physiol 2001. 281: L98–L107.
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism1997. Volume 1348, Issues 1–2, 4 Pages 79-90.
Am J Physiol Lung Cell Mol Physiol2001. Volume 281. Issue 1July Pages L108-L118
JBC1991. Volume 266, Issue 36, 25 December. Pages 24503-24508
Progress in Lipid Research. 2015.Volume 59, ages 147-171
Nature 2019. volume 575, pages 361–365
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 19 Feb 2024 - 30min - 682 - Biochemical Mosaic I. c.9 Increased inner mitochondrial membrane PE from PS decarboxylase decreases protease mediated degradation of phospholipid transfer proteins thus maintaining fusion potency.
References
PLoS Biol 2014. 12(10): e1001969
J Biol Chem. 2012 May18;287(21):17589-17597
J Biol Chem. 2012 Nov 23;287(48):40131-9
Nature 2019. volume 575, pages 361–365
Alleluia: Lobet den Herren.
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 19 Feb 2024 - 30min - 681 - Biochemical Mosaic I PA-phosphatase c.8. Membrane fusion and the dynamics of mitochondrial reduction vs. proliferation; the PA phosphatase in lipid metabolism. DJGPhD. 16.2.24 Authentic Biochemistry
References
Dr Guerra membrane lectures archive
FASEB J. 2021 Jun; 35(6): e21620.
Vivaldi, A. 1711. Concerto for 4 Violins in B minor RV 580
https://youtu.be/SY3Kxf7ZTeI?si=JLQXMtK06Y6Yfu_k
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 17 Feb 2024 - 29min - 680 - Biochemical Mosaic I. Phosphatidic acid Phosphatase. c.7. Mutational reversal of IDH1 leads to NADPH depletion concomitant with potent anti-PHD enantiomeric 2-hydroxyglutarate obtaining pseudohypoxia.
References FEMS Microbiol Rev.1998. Oct;22(4):255-75
Discoveries(Craiova). 2017 Jul-Sep; 5(3): e77.
J Cell Mol Med. 2015 Jul; 19(7): 1427–1440.
Oncogene. 2017 Mar 23; 36(12): 1607–1618.
Bach, JS. 1742. Kunst der Fuge , BWV 1080; Marta Czech
https://youtu.be/p1Sq1HOYglU?si=2GMF7kf3dLW4rr2O
Lennon and MCartney.1968. "Martha my Dear"
https://youtu.be/RXawa90YU2s?si=dUPDtTdm4UqrgWit
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 16 Feb 2024 - 30min - 679 - Biochemical Mosaic I. The PA phosphatase c.6. Alteration of the TCA pathway intermediates and hypoxia/nutrient deficiency control HIF1α stability indirectly regulating IMM protein and lipid turnover.
References
Front. Oncol. 2017. 26 November.V.7.
Oncogene. 2017 Mar 23; 36(12): 1607–1618.
Schubert, F. 1819 Piano Quintet in A major, D. 667/ "Trout"
https://youtu.be/syod5rkFdNY?si=5F3rexiou7dTifYg
Hunter, R., Garcia , J. 1970 "Ripple"
https://youtu.be/xofhZx9eWUQ?si=tpOAMzyW5qUy01P_
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportTue, 13 Feb 2024 - 30min - 678 - The Biochemical Mosaic I. Phosphatidic Acid Phosphatase c.5. Tumor cells adapt bioenergetic fuel economy toward cell immortalization via re-crafting of mitochondrial IM lipid speciation.DJGPhD.12Feb24
References
Cell Metabolism 2019. 30: 720–734
Nature 2019. 575: 361–365
Squire, C. 1978. "Onward" Yes.
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 12 Feb 2024 - 30min - 677 - Biochemical Mosaic I. Phosphatidic Acid Phosphatase c.4 GLN utilization and an IMM protease regulate mitochondrial involvement in cancer growth. DJGPhD. Authentic Biochemistry 10Feb24
References
Cell Death & Disease 2022. volume 13.Article number: 444.
Nature 2019. volume 575, pages 361–365
Scientific Reports 2021. volume 11, Article number: 16512
Experimental & Molecular Medicine2020. volume 52, pages 1496–1516
Mozart, WA. 1788. Piano Trio in G Major, KV 564
https://youtu.be/oOEuVtr8sF0?si=3-9RK1XkGkSWne7I
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSun, 11 Feb 2024 - 30min - 676 - Biochemical Mosaic Event Ontologies I. Phosphatidic Acid Phosphatase. c.3 Indirect consequences of mitochondrial proteomic variation potentially obtains GLN-linked Warburg glycolysis preventing ROS.
References
Cell Metabolism 2019. 30, 720–734
Redox Biology2013. Volume 1, Issue 1: 427-432
Nature 2019. volume 575. 361–365 Mozart, WA, 1779.Sinfonia Concertante Es-Dur, KV 364
https://youtu.be/iGDfj5uM_qA?si=bKNmj1r1o9zSMaA7
Lennon-McCartney. 1966. "Im Only Sleeping"
https://youtu.be/sAG3m3p9UeI?si=oT6Luxnc6eFS_pEq
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 09 Feb 2024 - 29min - 675 - Biochemical Mosaic Event Ontologies I. Phosphatidic Acid Phosphatase. Autophagy commitment is linked to mTORC1 v. AMPK oppostional kinase networks maintaining proteostasis and lipid homeostasis.DJGPhD
References
Nature 2019.volume 575, pages 361–365
Cells 2022, 11(21), 3339
Guerra: Polypeptide, endomembranous lipid homeostasis, and bioenergetics lecture archives.
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 09 Feb 2024 - 30min - 674 - Biochemical Mosaic Event Ontologies I. Phosphatidic Acid Phosphatase. Prologomena c.1.
References
J Cell Biol. 2014 Mar 17; 204(6):919–929
Nature 2019. Volume 575, pages 361–365.
Redox Biology 2013. Volume 1, Issue 1. Pages 427-432.
Madrigali Guerrieri et Amorosi {Libro Ottavo}https://youtu.be/2TjkhWARBVE?si=-ZI_kVa5WZX_9qnB
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 07 Feb 2024 - 30min - 673 - BioMedical Portrait VIII. C.22 CODA. Microglial Leukotrienes in neurodegeneration.DJGPhD.04Feb2024. Authentic Biochemistry Podcast.
References
Acta Neuropathologica Communications 2020. volume 8, Article number: 129.
J Lipid Res. 2019 Feb; 60(2): 219–226.
Palestrina, G. 1562. Missa papae Marcelli
https://youtu.be/KSmT4VIjEtI?si=6s7MtdTuH0fsURU5
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSun, 04 Feb 2024 - 30min - 672 - BioMedical Portrait VIII. c.21 Lysopholpids like sphingolipids hydrogen bond to cholesterol mediating lipid membrane raft mobility. DJGPhD. 2Feb2024. Authentic Biochemistry Podcast
References
Biochimica et Biophysica Acta (BBA) - Biomembranes2015. Volume 1848, Issue 3, Pages 805-812
Soft Matter 21-Jan-2021
Am J Rhinol Allergy. 2015 Jan-Feb; 29(1): 35–40.
Scientific Reports2017. volume 7, Article number: 39661.
Antioxid Redox Signal. 2011 Aug 15;15(4): 1043–1083. Journal of Immunotoxicology. 2008. 5:4, 347-352
Mozart, W. A. 1773, October.Symphony No. 25 in G minor K.183.
https://youtu.be/707oHEGF6l8?si=J_WI-BhX0cvI9caQ
Jon Anderson, Chris Squire, Bill Bruford, and Steve Howe, 1972. "And You and I".
https://youtu.be/IwpB6b6mhUM?si=MF15_eWTCPVaqeEO
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 03 Feb 2024 - 29min - 671 - BioMedical Portrait VIII C.20. Heterologous lipid sequence membrane domains rearrange according to LysoPL polarity after PLA2 mediated 20:4 removal and acetosalicylic acid alters fatty acid ordering.
References
Soft Matter, 2021,17, 2742-2752
BBA Biomembranes2015 Volume 1848, Issue 3, Pages 805-812
Mozart, WA. 1788. Divertimento in E Major.K 563.
https://youtu.be/E8c83bpOVXo?si=AUrRoRH0C1ie2xd0
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 01 Feb 2024 - 30min - 670 - BioMed PortraitVIII.c.19. Membrane thermotropic phase transition enthalpic responses to Leukotriene synthesis in relation to cholesterol and lysophospholipid fluid dynamics.DJGPhD.31.1.24.Authentic BC
References
Dr Guerra: membrane lectures
Balin, M.1966. "Coming Back to Me" Jefferson Airplane. Surrealistic Pillow.1967. https://youtu.be/y2f3tlgApHw?si=cTa1nhYw6kcycxUs
Dylan (Zimmerman),R. 1962 "Girl from the North Country". w. Johnny Cash.
https://youtu.be/Je4Eg77YSSA?si=eYXfJhwOQisGjPHW
Schubert, F. 1828.Piano Sonata in B-flat major, D.960
https://youtu.be/lncNcNtGkJY?si=KRTh3hQStQ3x51Ug
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 31 Jan 2024 - 29min - 669 - BioMed Portrait VIII.c.18Aspirin PGS (COX) inhibited membrane topological and integrated molecular dynamics: leukotriene –cytokine mediated asthmatic inflammation.DJGPhD.29.1.24. Authentic Biochem.
References
Biochimica et Biophysica Acta (BBA) - Biomembranes2015. Volume 1848, Issue 3. Pages 805-812.
J Immunol. 2018 Feb 1; 200(3): 915–927.
Am J Rhinol Allergy. 2015 Jan-Feb; 29(1): 35–40.
Corelli,A. 1714. Concerto in D Major Op. 6 No. 4,
https://youtu.be/3smZkpqXYHs?si=uwEdDkRv-bz-zJXW
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 29 Jan 2024 - 29min - 668 - Sententia non Fengo, concluding remarks. BioMedical PortraitVIII. (C.17). LTC4 and LTD4 interact with IL-33 inducing cytokine generation in lung ILC2s.DJGPhD.28.1.24
References
J Immunol. 2018 Feb 1; 200(3): 915–927
Fontana, GB. 1641 Violin Sonata 2.
https://youtu.be/2kkpqJkYmms?si=w-JT4cbsn9hl7GSP
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 29 Jan 2024 - 29min - 667 - Sententia non Fengo: A minor prolegomenon to the purpose of Authentic Biochemistry. DJGPhD.28.1.24
References
Plotinus. 204-270. ""Neoplatonist philosophy:The Enneads
Kant, I. 1790. Critique of Judgment.
Beatles. 1969. Abbey Road.
https://youtu.be/oolpPmuK2I8?si=BKTiNJmp-omJ8lJH
Aleotti, V. 1575-1620. Audivi vocem de caelo
https://youtu.be/CaTNXjzQANs?si=Zh3whogggigHmp4i
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSun, 28 Jan 2024 - 29min - 666 - BioMed Portrait VIII. c.16. Coordinated complimentarity of cell cycle MEK kinase cascade with the IL33-ST2 and CysLT1R mediatedILC2 activation to promote type 2 immunopathology. DJGPhD.25.1.24
References
J Immunol. 2018 Feb 1; 200(3): 915–927
Cells. 2020 Jan; 9(1): 198.
Cells. 2022 Apr; 11(7): 1105
Nature Comm. 2020. volume 11, Article number: 35
Schubert F. 1829. Fantasie in F minor. D940
https://youtu.be/UyjzqPPXDcw?si=XW_SMP7j-Kza8pmq
Winwood, Capaldi and Wood. 1967 (Traffic). "Dear Mr Fantasy"
https://youtu.be/dyMiUmrouZU?si=1ZSdXupm3WFBAxTz
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 26 Jan 2024 - 30min - 665 - BioMedical Portrait VIII.c.15. ILC associated hippocampal RNA-BP's exacerbate GLU neurotoxicity and regulate CysLT1R in lung ILC2's. DJGPhD. 23.1.24.
References
Nat Commun. 2022; 13: 4435.
Nat Commun 2020; 11: 35
Hayward, J. 1971. "You Can Never Go Home" Moody Blues.
https://youtu.be/mUhboF8d1x0?si=IX4iP_W0f3uR65qo
Jagger, Richards, Oldham. 1964. "As Tears Go By". Marianne Faithful.
https://youtu.be/S8EykQaZ8CU?si=X42TiNsveR7rwdHB
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportTue, 23 Jan 2024 - 29min - 664 - BioMedical Portrait VIII.c.14 The dialectical events between immune responses and leukotriene signaling are modulated by tissue-resident and circulating cell patterns via RNA binding proteins.DJGPhD.
References
Nat Commun. 2022; 13: 4435.
Virchows Archiv: European Journal of Pathology, 2020. Vol. 476, Issue 2
Cell Death Differ. 2015 Apr; 22(5): 703–718
Pentangle.1971. Hunting Song.
https://youtu.be/CwvpMGc_J-w?si=s6pS2agc5s1N0H2z
Falconieri , Cima, Uccellini, Turini, Merula, et al. 1600-1650. Early Italian Baroque Ensemble.
https://music.youtube.com/playlist?list=OLAK5uy_mQznM05seareQTK-s3j-1VgS4DHblD5po&si=3mJts6TW3-T2g7k5
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 22 Jan 2024 - 29min - 663 - BioMedical PortraitVIII.c.13 Leukotriene metabolism and reception is linked to innate like lymphocytes involved in airway inflammation and hyper-responsiveness-associated asthma.DJGPhD.19.1.24.AB.
References
J Immunol. 2009 Feb 1; 182(3): 1641–1647. Cell Reports 2015 10, 2043-2054DOI
Virchows Archiv:European Journal of Pathology. 2020. 09456317, Vol. 476, Issue 2
Poe, EA. 1845. "the Raven" https://youtu.be/wAdQ3CcPHQU?si=2qpStYF2gdUJ4f35
Buddy Morrow and his Orchestra. 1960. "the Black Cat"
https://youtu.be/9w_VL7oq-mE?si=XiorgTkvSGzJ4BK0
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 20 Jan 2024 - 29min - 662 - BioMedical Portrait VIII.c.12. 5-LOX associates with FLAP and PLA2 at the nuclear envelope to trigger and control ILC2 mediation of the allergic asthma AHR pathology. DJGPhD 17.1.24. Authentic Bioch.
References
Immunology. 2019 Apr; 156(4): 402–412.
J Immunol. 2017 Aug 1; 199(3): 1096–1104
Front. Immunol., 06 June 2019
Mol Biol Cell. 2012 Nov 15; 23(22):4456–4464.
Virchows Archiv: European Journal of Pathology, 09456317, Feb2020, Vol. 476, Issue 2
Pavana, Gagliarda, Ciaccona, Passacaglia 1535-1615.
https://youtu.be/AY533zpCw74?si=224HuGs438aPHrrd
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 18 Jan 2024 - 30min - 661 - BioMedical Portrait VIII. C.11 Peptidyl leukotrieneR- mediated transcription of PTGS2and LOX15B with IL4/IL13 and IL33 in asthmatic lung airway constrictionin MDM's LM's and ILC2's DJGPhD.16.1.24
References
Immunol.2017 Aug 1; 199(3): 1096–1104.
British J of Pharmacology. 2015. Volume172, Issue17: 4319-4330
Beethoven, L. 1826. String Quartet Op. 135 in F Major (#16)
https://youtu.be/1hxpIQ3XhXA?si=65eTt7TlOZYCNsG8
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 17 Jan 2024 - 29min - 660 - BioMedical Portrait VIII. c.10. The LOX5 and LOX12/15 pathways for 20:4, 20:5 and 22:6produce over 50 unique molecular species of oxylipins and lipoxins with unique biological sequalae.DJGPhD.14.1.24.
References
Int.J. Mol. Sci. 2022, 23(23), 14883.
Prostaglandins Other Lipid Mediators. 2023 Jun:166:106726.
British J of Pharmacology. 2015. Volume172, Issue17. 4319-4330
Mozart, WA. 1791. Requiem.D Minor, K. 626
https://music.youtube.com/watch?v=RDegrbjfiWU&si=x-SSYDxEOv5Vc4xE
Miller, S. 1977. Wintertime.
https://youtu.be/HUv7pXgZ9NA?si=JzaZOWKLkPEMiyKj
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 15 Jan 2024 - 29min - 659 - BioMedical Portrait VIII. c.9. Initial detail of the LOX vs.COX isoform utilization of essential and other dietary PUFA's in complex leukotriene biosynthesis. DJGPhD.11Jan24.Authentic Biochemistry.
References
British J of Pharmacology 2015. Volume172, Issue17September Pages 4319-4330
Prostaglandins Other Lipid Mediators. 2023 Jun:166:106726.
1718. Concerto No. 4 in F minor, Op. 8, RV 297, "Winter" (L'inverno)
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 12 Jan 2024 - 30min - 658 - BioMedical Portrait vIII. Leukotrienes. c.8 Leukotriene regulated Heterodimer Nuclear Receptor transcription factors organize around complex multi-ligand binding and sojourner molecular modifiers
References
British J of Pharmacology 2015. Volume172, Issue17 September Pages 4319-4330
Chem Rev. 2011 Oct 12; 111(10): 6321–6340
JBiol Chem. 2020 Jul 17; 295(29): 10045–10061
Mozart, WA. 1768. January. Symphony #7 in D major K.45.composed in Vienna just 10 days before he turned 12 years old.https://youtu.be/ABOle_eSq9c?si=GcA8EvXbpEZP0W0A
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 10 Jan 2024 - 28min - 657 - BioMedical Portrait VIII.c.7. Differential control over fatty acid oxygenation and PPAR/RXR heterodimer pairing in mammalian uterine cell estrus physiology.DJGPhD.8Jan2024
References
General and Comparative Endocrinology,2018-06-01, Volume 262, Pages 27-35
Pisendel JG 1735.Violin Concerto in D major, JunP I.5.
https://youtu.be/dvwhXXvFiNg?si=YfS2waKLC5WHy0En
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportTue, 09 Jan 2024 - 30min - 656 - EtOH Membrane Intoxication c.3. Epiphantei: ethanol-induced membrane degeneration results in altered porosity/tortuosity dynamics and microglia-failed tissue surveilance/repair in the CNS.DJGPhD.
References
Brain Imaging Behav. 2011 Sep; 5(3): 189–202
PLoS One. 2019; 14(1): e0210888.
Alcohol, 2017-12-01, Volume 65, Pages 51-62
Clapton, E. and Martin Sharp .1967 "Tales of Brave Ulysses"
https://youtu.be/I32Wwfv8v1U?si=TfUX6Xldenp_f5M5
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 06 Jan 2024 - 30min - 655 - EtOH c.2 Mean diffusivity and tortuosity metrics in ethanol induced white matter lesions.
References
PLoS One. 2019; 14(1): e0210888
Trends Neurosci. 2015 Jun; 38(6): 364–374
Addict Biol. 2006 Sep; 11(3-4): 339–355
Sci Rep. 2022; 12: 19463.
Beethoven, L. 1809. Piano Concerto #5 in E-flat major, Op. 73, "Emperor Concerto "
https://youtu.be/kiW-QnQzN9Y?si=qT6PgbhB9L5jpzcZ
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 06 Jan 2024 - 30min - 654 - BioMedical Portrait VIII.c.6 Precursor 20:4 5,8,11,14 derived prostaglandins and leukotriene roles in PPAR and RXR transcription factor expression in mammalian reproductive tissues. DJGPhD. 04JAN24.AB
References
General and Comparative Endocrinology 2018-06-01, Volume 262, Pages 27-35.
Immunohorizons. 2022 Jun 22; 6(6): 366–372.
Biochem J. 2009 Dec 14;425(1):265-74.
Nature. 2023; 614(7948): 530–538.
Winwood,S. 1969 Blind Faith "Had to Cry Today".
https://youtu.be/Z4Yo_VbGdMg?si=3whbMcoWNFtfgPwE
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 04 Jan 2024 - 30min - 653 - Post Holiday EtOH Lectures. Volume One. Dr. Daniel J. Guerra. 01Jan2024. Authentic Biochemistry
References
Sci Adv. 2020 Jun; 6(26): eaba0154
Brahms , J. 1869 Schicksalslied ∙ hr-Sinfonieorchester.
https://youtu.be/yC8CNpFu_7Q?si=ZqE0nuvXjaRJVcMh
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportTue, 02 Jan 2024 - 27min - 652 - BioMedical Portrait VIII.c.5 Leukotrienes. Lipoxygenase isoform mediated control over resident tissue macrophage speciation.Dr Daniel J. Guerra. 01Jan2024. Authentic Biochemistry Podcast
References
Immunohorizons. 2022 Jun 22; 6(6):366–372.
Biochem J. 2009 Dec 14;425(1):265-74
Chem Rev. 2011 Oct 12; 111(10): 6321–6340.
Telemann, Georg Philipp. 1699.Trauer-Actus, Cantus Cölln, Junghänel
https://youtu.be/0yS7YIcwBq0?si=UaVMZzBtZc27t5Xp
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 01 Jan 2024 - 29min - 651 - BioMedical Portrait VIII. c.4 A deft-handed apprehension of chirality to facillitate reasoned appreciation of leukotriene molecular heterogeneity.DJGPhD. 30.12.23. Authentic Biochemistry.
References
Dr Guerra-notes
Schubert. F. 1815 (late March-Early April. Stringt Quartet No. 9 in G minor (D.173)
https://youtu.be/piIet7QVLGA?si=FcY0VUUXRPPekKs1
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSun, 31 Dec 2023 - 29min - 650 - BioMedical Portrait VIII.c.3. Leukotriene molecular speciation involves subcellular re-distribution of modifying enzymes and adaptor proteins associating with ER and Nuclear membranes.DJGPhD.28.12.23
References
Infect Immun. 2021 Aug; 89(8): e00095-21.
Eur J Immunol. 1992 Oct;22(10):2705-11
Progress in Lipid Researc 2015. hVolume 57, January Pages 13-39
Am J Physiol. 1999 Apr;276(4):C988-94.
Beethoven, L. 1813, 08 December.: Symphony no. 7 in A major, op. 92.
https://youtu.be/T7CjuvE8oFA?si=il248jF2v7njd-Jo
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 29 Dec 2023 - 29min - 649 - BioMedical Portrait VIII.c.2 Leukotrienes: regio-associated oxygenation patterns of lipoxins and peptido-LTC's distrubute among pro-inflammatory states . DJGPhD. 27.12.23. Authentic Biochemistry
References
Am J Physiol . 1999 Apr;276(4):C988-94. Acta Derm Venereol 2017; 97: 922–927 Signal Transduction and Targeted Therapy 2021.volume 6,Article number: 94
J Adv Res. 2018 May; 11: 33–41.
Progress in Lipid Research 2015.Volume 57, January:13-39
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 28 Dec 2023 - 29min - 648 - BioMedical Portrait VIII. c.1 Leukotrienes: an Introduction. Dr Daniel J. Guerra. 26.12.23 Authentic Biochemistry Podcast.
References
J Periodontol, 2007. August 1. 78(8): 1620-6.
Annu. Rev. Pharmacol. Toxicol. 2023. 63:407–28
Acta Derm Venereol. 2017; 97: 922–927
Moody Blues 1967.Nov10. Days of Future Passed.
https://youtu.be/uZCzH8q1hcY?si=2cWl06wuBC4itE1k
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 27 Dec 2023 - 29min - 647 - Christmas Eve Special:Research science relies on the means by which it is apprehended thus continuously challenged and improved with the goal of finding truths about nature in perpetuity.DJGPhD
References
Guerra's epistemology and metaphysics :brief sketch
Baroque Christmas Concert with works by Bach, Handel and Mozart Freiburg Baroque Orchestra
https://youtu.be/3VupBizhIn4?si=jBOcxwesBtMPv_I1
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 25 Dec 2023 - 27min - 646 - Dyslipidaemia Coda IV. Antinomies and paralogisms in discerning apoplipoprotein contribution to HTG vs.CAD. DJGPhD.21.12.23.Authentic Biochemistry.
References
Biomolecules 2021, 11(7), 1016
Journal of Clinical Lipidology
Volume 16, Issue 4, July–August Pages 472-482Schubert. F. 1825.Symphony No. 9 in C major, D 944,
https://youtu.be/Ip06DEeY_U8?si=pP8NP22m9XXmpz7z
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 21 Dec 2023 - 29min - 645 - Dyslipiaemia Coda III. The proposed use of apolipoprotein serum concentration and hyperTAG may require a deeper analysis at the transcriptomic and proteomic levels. DJGPhD.20.12.23 Authentic Biochem.
References
Biomolecules 2021, 11(7), 1016
Journal of Clinical Lipidology
Volume 16, Issue 4, July–August Pages 472-482Lennon-McCartney 1964. If I Fell https://youtu.be/F_80s6S_7Vw?si=PmlyAATePHfqmzqv
Lennon-McCartney. 1963. Misery.https://youtu.be/qhbcN3ew9z0?si=DvePBioaAgZ7_dRW
Alexander. A. 1962. Anna. Cover by the Beatles.
https://youtu.be/b3zNKWyLfus?si=kEaNqNy_JF_HZNji
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 21 Dec 2023 - 30min - 644 - DYSLIPIDAEMIA CODA II. Hypertriacylglycerolaemia is linked to mutations in LPL and various apolipoproteins linking CAD to TAG. 18.12.23. DJGPhD.Authentic Biochemistry
References
Journal of Clinical Lipidology. 2022. Volume 16, Issue 4, July–August. Pages 472-482.
Guerra. 2023. -Lecture notes
JLR.2012. Volume 53, Issue 9, September. Pages 1783-1799
Mozart, WA. 1782 Serenade No12 C.Minor. K388/384a
https://youtu.be/xOaP9G-9wi8?si=CE8d9hcuUfbaqa4z
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 18 Dec 2023 - 29min - 643 - BioMedical Portrait VII. C.7. Lipoprotein biosynthesis and apolipoprotein structure. DJGPhD. 16.12/23. Authentic Biochemistry
References
Dr Guerra-lecture notes
Journal of Clinical Lipidology2022.Volume 16, Issue 4, July–August Pages 472-482
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 16 Dec 2023 - 29min - 642 - BioMedical Portrait VII.c.6 Lipoprotein Lipase regulation performs a critical role in lipid homeostasis as evidenced by chylomicron clearance resistance in obese dyslipidaemic adolescents and adults.
References
Nutrients. 2021 Jan 28;13(2):413
Nutrients. 2022 Jun 12;14(12):2438
J Diabetes Investig. 2023 Oct;14(10):1148-1156
Clinica Chimica Acta 2020. Volume 508, September Pages 61-68
Vivaldi. A. 1715. Gloria RV.589 https://youtu.be/XxwtYIKI9dE?si=ksQHEkQf5OlBpHCR
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 14 Dec 2023 - 30min - 641 - BPVII.c.5 Diminished circ.LPL and adiponectin in obese adolescents correlates with higher dyslipidaemic T2D, MetSynD, and insulin resistance via inflammation-triggering lipoprotein non-clearance.
References
Nutrients. 2021 Feb; 13(2): 413.
Advances in Clinical ChemistryVolume 64, 2014, Pages 117-177.
Front Physiol. 2020; 11: 796.
Int J Mol Sci. 2023 Sep; 24(18): 13942.
J Diabetes Investig. 2023. Oct;14(10):1148-1156.
Nutrients. 2022 Jun 12;14(12):2438
RNA Biol. 2023; 20(1): 737–749.
Clinica Chimica Acta
Volume 508, Pages 61-68Kirwan, Danny. 1971. "Sands of Time" Fleetwood Mac Lp Future Games https://youtu.be/1Jkp34jMeEw?si=fRzdAiA525bHRX5k
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportTue, 12 Dec 2023 - 30min - 640 - BioMedical Portrait VII. C.4 Chylomicron associated endothelial luminal LPL differential interaction with ANGTPL isoforms reults in unique TRL disposition. DJGPhD.10Dec23
References
J Diabetes Investig. 2023Oct;14(10):1148-1156
J Pediatr. 2021 Apr; 231: 200–206.e1.
Front Physiol. 2020; 11: 796.
ClinicaChimicaActa.2020 Volume 508, September Pages 61-68 Mozart,WA. 1787. Eine kleine nachtmusik K.525
https://youtu.be/nPbxIT9W1AY?si=mgzBQzpvuFzsVNtB
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 11 Dec 2023 - 29min - 639 - BioMedical Portarit VII. c.3. Introduction to chylomicron apoB48 and the angiopoietin-like LPL inhibitor contributions to circulating TAG. DJGPhD.9DEC23. authentic Biochemistry
References
Am J Physiol Endocrinol Metab. 2021 Oct 1; 321(4): E493–E508.
Clinica Chimica Acta
Volume 508, September Pages 61-68Advances in Clinical Chemistry
Volume 64, Pages 117-177Pancreas. 2017 Aug; 46(7): 874–879
Mozart WA 1775 Violin Concerto in G major, K. 216
https://youtu.be/j7Z6gouAVCc?si=X-3AnGtJoVvf7aF9
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSat, 09 Dec 2023 - 29min - 638 - BioMed Portrait VII. c.2 Lipoprotein lipase mediated TAG delivery and adolescent obesity. DJGPhD.6Dec23. Authentic Biochemistry
References
Clin Chim Acta . 2020 Sep:508:61-68
Applied Physiology, Nutrition, and Metabolism.2021. Volume 46, Number 8.
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 07 Dec 2023 - 29min - 637 - BioMedical Portrait VII. Lipoprotein Lipase Pathobiochemistry. Prolegomena. DJGPhD. 5Dec23 Authentic Biochemistry
References
J Diabetes Investig.2019 Nov; 10(6): 1430–1437.
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 06 Dec 2023 - 30min - 636 - Bio Med Portrait. c.16. NK cells promote the inflammatory court in NAFLD via mutations in lipid metabolism and excessive GK mediated glycolysis and lipogenesis in hepatocytes DJGPhD.3Dec23b
References
Front. Immunol., 21 August 2019 Sec. Cancer Immunity and Immunotherapy Volume 10
Front Immunol. 2021; 12: 640869
PLoS One. 2014; 9(2): e87523
Vivaldi, A. 1719. "L 'inverno".
https://youtu.be/pCqO-0339k0?si=k5xtuT8x7SfJeLok
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 04 Dec 2023 - 29min - 635 - BioMed Portrait VI.C.15 Characterization of four lipid and glucose metabolic polypeptides linked to obesity/T2D and NASH-->HCC.DJGPhD.3Dec23.Authentic Biochemistry Podcast
References
Guerra-intermediary metabolic lecture archives
ProcNatl Acad Sci U S A. 2014 Jun 17; 111(24): 8913–8918
Nutrition, Metabolism and Cardiovascular Diseases, 2023-09-01, Volume 33, Issue 9, Pages 1785-1796.
Int J Cancer. 2019 Feb 1;144(3):533-544
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSun, 03 Dec 2023 - 30min - 634 - BioMedical PortraitVI.C.14.Liver NK cell chemokine recruitment and the significant role of obesity in possible immunotoxicity in HCC ontogeny.DJGPhD.30.11.23
References
Journal of Hepatology 2012 56, 704-713DOI
Eur J Immunol. 2019 Jan;49(1):38-41
Front Immunol. 2016; 7: 19.
Immun Ageing. 2020; 17: 16.
Proc Natl Acad Sci U S A. 2014 Jun 17; 111(24): 8913–8918.
Cells. 2021 Jun; 10(6): 1332
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 01 Dec 2023 - 30min - 633 - BioMedical PortraitVI.c.13. Senescense and the aging of cells within systems apprehends the event ontologies of the stress phenomena-immune surveillance axis.DJGPhD.29.11.23. Authentic Biochemistry.
References
Annual Review of Pathological Mechanisms of Disease 2010. 5:99-118.
Immun Ageing. 2020; 17: 16
Williams, Hank.1949.ISLICC.
https://youtu.be/4WXYjm74WFI?si=mhYowh4ClIOKmgVX
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 30 Nov 2023 - 30min - 632 - BioMedical Portrait VI. c.12. Obesity and viral infection-associated NK malfunction may lead to NASH and subsequent HCC. DJGPhD.28.11.23. Authentic Biochemistry
References
Ann. Review of Pathological Mechanisms of Disease2010.5:99-118.
Nature 2013 Jul 4;499(7456):97-101.
Front Immunol. 2018; 9: 476
Cells. 2021 Jun; 10(6): 1332
Nat Rev Gastroenterol Hepatol (2023). https://doi.org/10.1038/s41575-023-00846-4
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 29 Nov 2023 - 30min - 631 - BioMedical Portrait VI. c.11 NK cell involvement in HepatoCellular Carcinoma. DJGPhD. 26.11.23. Authentic Biochemistry
References
Front Immunol. 2018; 9: 476
Nature Reviews Gastroenterology & Hepatology2023. 20: 662–678 (2023)
Cells. 2021 Jun; 10(6): 1332.
Traffic, (Traditional. arr. S Winwood )1970. "John Barleycorn Must Die" https://youtu.be/icyPFsIcAV0?si=XSVxsiojZBrwGPx6
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportMon, 27 Nov 2023 - 30min - 630 - "The Universe by Negation" DJGPhD.23.11.23
References
Dr Guerra's Metaphysics notes
Schubert, F. 1828. Quintet in C. Major D.956
https://youtu.be/Dc3iX7x73JY?si=j4jlU4ra_488pAuE
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 24 Nov 2023 - 28min - 629 - BioMedical Portrait VI.c.10.Alterations in the cytotoxic immune response can be dissociated from inflammation via intermediary metabolic mutation.DJGPhD.22.11.23. Authentic Biochemistry Pootdcast.
References
Front Immunol. 2023; 14: 1151166.
Dr Guerra: Biochemistry lecture archives
Telemann, G.P. 1725.Viola Concerto in G major
https://youtu.be/yMpzPMkrALM?si=lpyDYITx63jTc6-K
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 23 Nov 2023 - 30min - 628 - BioMedical PortraitVI.c.9 HLH mutations obtain complex NKvs.CD8+ T cell alterations in cytototoxicity and proliferation.DJGPhD.21.11.23 Authentic Biochemistry.
References
Immunobiology. 2019 Jan; 224(1): 94–101
Front. Immunol., 14 June 2023
Cell. 2003 Nov 14;115(4):461-73
VonBingen.H. Born 1098AD
https://youtu.be/yyAQc0kPZpU?si=y26mnCOmFpRis63_
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportWed, 22 Nov 2023 - 29min - 627 - BioMedical Portrait VI.c.8.The cytotoxicity of the NK cell Is a function of its bioenergetics. Glycolysis/OXPHOS vs. FAO/OXPHOS during activation/proliferation
References
Front Immunol. 2023; 14: 1151166.
Inflammation Research :official journal of the European Histamine Research Society 2018.1420-908X, Vol. 67, Issue 10.
J Cell Sci. 2011 Dec 15; 124(24): 4147–4159.
Hunter, R. and J. Garcia 1970. "Sugaree"
https://music.youtube.com/watch?v=sxF9UJ-Rm0E&si=S4F0LvlFvUsTE1OO
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportTue, 21 Nov 2023 - 29min - 626 - BioMedical PortraitVI.C.7 IEI/IEM pathobiochemistry involves bioenergetics, transcriptional , translational, and post-translational modification sequalae.DJGPhD.19.11.23 Authentic Biochemistry.
References
Front Immunol. 2022; 13: 950536.
Inflamm Res. 2018 Oct;67(10):813-828
Mol Biol Rep. 2023; 50(8): 6963–6974.
Front Immunol. 2023; 14: 1151166
Dr Guerra: Graduate biochemistry lecture archive
Schubert.F. 1827.December.Impromptu #3 in G flat major performed by Khatia Buniatishvili
https://youtu.be/LUp2u9wI1fY?si=hhiUmiyXyQ78Qtaw
and "Questions" Manfred Mann 1976.
https://youtu.be/qvvstrKLvts?si=-I8bGmB2oC3FpPLw
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportSun, 19 Nov 2023 - 30min - 625 - BioMedical Portrait VI c.6.Hemophagocytic lymphohistiocytosis ACAD9/Rab27A/+/- FBase1 mutations linked to NK and CTL immunodeficiences.DJGPhD. 16/11/23. Authentic Biochemistry.
References
Front Immunol. 2023; 14: 1151166.
Int J Mol Sci. 2019 Jan; 20(2): 443.
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportFri, 17 Nov 2023 - 29min - 624 - BioMed Portrait VIc.5. NK cell Inborn Error Of Immunity links to failed fatty acyl CoA dehydrogenase-obtained immunodeficiency.DJGPhD. 15.11.23. Authentic Biochemistry
References
Front Immunol. 2023; 14: 1151166
--- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/supportThu, 16 Nov 2023 - 30min
Podcasts similar to Authentic Biochemistry
- Global News Podcast BBC World Service
- El Partidazo de COPE COPE
- Herrera en COPE COPE
- The Dan Bongino Show Cumulus Podcast Network | Dan Bongino
- Es la Mañana de Federico esRadio
- La Noche de Dieter esRadio
- Hondelatte Raconte - Christophe Hondelatte Europe 1
- Dateline NBC NBC News
- 財經一路發 News98
- La rosa de los vientos OndaCero
- Más de uno OndaCero
- La Zanzara Radio 24
- L'Heure Du Crime RTL
- El Larguero SER Podcast
- Nadie Sabe Nada SER Podcast
- SER Historia SER Podcast
- Todo Concostrina SER Podcast
- 安住紳一郎の日曜天国 TBS RADIO
- TED Talks Daily TED
- アンガールズのジャンピン[オールナイトニッポンPODCAST] ニッポン放送
- 辛坊治郎 ズーム そこまで言うか! ニッポン放送
- 飯田浩司のOK! Cozy up! Podcast ニッポン放送
- 吳淡如人生實用商學院 吳淡如
- 武田鉄矢・今朝の三枚おろし 文化放送PodcastQR