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LEVELS – A Whole New Level

LEVELS – A Whole New Level

Levels

Levels builds tech that helps people understand how food affects their metabolic health, empowering others with the tools needed to achieve health goals and improve health span. We host in-depth conversations with industry thought leaders with research-backed information, so you can take your health into own hands. Connect with us: Become a Member: https://levels.link/wnl Instagram: https://instagram.com/levels Twitter: https://twitter.com/levels LinkedIn: https://linkedin.com/company/levels-health TikTok: https://tiktok.com/@levelshealth YouTube: https://youtube.com/levelshealth

253 - #253 - What is insulin resistance and why does it matter? | Dr. Rob Lustig & Dr. Dominic D’Agostino - (Replay)
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  • 253 - #253 - What is insulin resistance and why does it matter? | Dr. Rob Lustig & Dr. Dominic D’Agostino - (Replay)

    Insulin resistance is when cells stop responding to insulin’s signal to uptake glucose. It’s a hallmark of prediabetes, Type 2 diabetes, and other forms of metabolic dysfunction, and it manifests as several chronic disease, ranging from Alzheimer’s to polycystic ovarian syndrome. Dr. Rob Lustig and Dr. Dominic D’Agostino discuss the importance of monitoring insulin levels, why a high or increasing insulin level is a problem, and how insulin resistance hinders weight management.


    Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠https://levels.link/wnl⁠


    Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

    Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

    🎙 What Rob Lustig, MD, & Dr. Dominic D’Agostino, PhD, discuss:

    (03:57) — What is insulin?

    (06:55) — What is insulin resistance?

    (18:00) — There are three types of insulin resistance

    (38:00) — Weight management is not about calories in and calories out

    (45:53) — Adding more insulin to the equation of Type 2 diabetes isn’t necessarily the answer

    (51:20) — Insulin is a crucial biomarker to measure for metabolic health

    (53:58) — Insulin resistance is a hinderance to weight management

    (57:07) — The intake of too much leucine can lead to insulin resistance

    (1:02:04) — Fiber feeds the gut microbiome and is crucial for metabolic health

    (1:13:11) — Is intermittent fasting necessary?

    ⁠Transcripts & Show notes⁠

    🔗 Helpful links:

    Watch the conversation: ⁠https://youtu.be/dFOaBrujDHo⁠

    Thu, 09 May 2024 - 1h 21min
  • 252 - #252 - Why nutrition matters for brain health and how to modify your diet | Dr. Georgia Ede & Dr. Dominic D’Agostino - (Replay)

    The ketogenic diet is a low-carbohydrate, high-fat diet that has proven benefits for brain health. Research shows that the keto diet helps ease symptoms of some mental health conditions, including depression and bipolar disorder. But no diet, even keto, is one-size-fits all. Dr. Georgia Ede and Dr. Dominic D’Agostino discuss how diet and brain health are connected, how diet and gut health affect brain health, and how a ketogenic or other low-carbohydrate diets can be tailored to people’s specific needs.


    Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠https://levels.link/wnl⁠⁠


    Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

    Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.


    🎙 WhatGeorgia Ede, MD& Dominic D’Agostino, PhD, discuss:

    (06:51) — Dr. Georgia Ede describes her interest in nutritional science for mental health

    (16:45) — Metabolic health is tied to brain health

    (23:16) — A ketogenic diet vs medications for mental health

    (27:19) — A ketogenic diet can be tailored to prevent side effects

    (32:51) — Gut health and mental health are connected

    (39:00) — Diet is highly individual

    (42:02) —CGM can teach people how foods and diet strategies affect their health

    (44:57) — Following a low-carbohydrate diet will generally reduce insulin levels and triglycerides

    (47:40) — Some psychiatric symptoms have links to higher C-reactive protein levels

    (48:42) — Dr. D’Agostino summarizes one of Dr. Ede’s studies on the ketogenic diet and mental health

    (56:59) — A ketogenic diet may also help ease some menopause symptoms

    ⁠Transcripts & Show notes⁠

    🔗 Helpful links:

    Watch the conversation: ⁠⁠https://youtu.be/kBjBEjV0vqU⁠

    Find us on YouTube: ⁠⁠https://youtube.com/levelshealth?sub_confirmation=1

    Thu, 25 Apr 2024 - 1h 18min
  • 251 - #251 - How to track your macros for fat loss and muscle gain | Josh Clemente & Dominic D'Agostino

    Not all calories are equal. Tracking your macronutrient intake, using AI capabilities, can help you improve your body composition, facilitate weight loss, and boost exercise performance. The three macronutrients are protein, fat, and carbohydrates, with fiber a subset of carbs. Josh Clemente & Dr. Dominic D'Agostino discuss the new macros-tracking feature in the Levels app, the purpose and importance of each macronutrient, how to use macros-tracking in conjunction with biomarker data to improve health and fitness, and how easy the app’s AI functionality is to use.


    Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠⁠⁠⁠https://levels.link/wnl⁠⁠⁠⁠


    Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

    Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.


    🎙 WhatJosh Clemente & Dominic D'Agostino, PhD, discuss:

    (09:03) — The importance of prioritizing protein intake

    (17:03) — Why is tracking macros beneficial?

    (21:11) — Each macronutrient has a different role in the body

    (39:36) — The different functions of macros

    (48:32) — Is excess protein a concern?

    (54:55) — The problem with excess carbohydrates

    (1:00:37) — Tracking macros can help you improve metabolic flexibility

    (1:02:41) — The issue with overconsumption of carbohydrates

    (1:17:18) — Is fiber a macronutrient?

    (1:46:21) — Macros tracking in the Levels app

    (1:49:50) — Tracking macros can help improve body composition and performance

    Transcripts & Show notes

    🔗 Helpful links:

    Watch the conversation: https://youtu.be/wg76Q25Ngd4

    Find us on YouTube: ⁠⁠⁠⁠⁠https://youtube.com/levelshealth?sub_confirmation=1⁠⁠

    Thu, 18 Apr 2024 - 1h 47min
  • 250 - #250 - Is fructose a driver of Alzheimer’s disease? | Dr. Richard Johnson & Dr. Rob Lustig - (Replay)

    Fructose and its byproduct uric acid may play a role in the development of Alzheimer’s, thanks to an evolutionary adaptation hijacked by the modern diet. Fructose can be directly consumed, or the body can convert high-glycemic carbohydrates and other foods to fructose. Fructose suppresses some cognitive functions. Dr. Richard Johnson and Dr. Rob Lustig discuss a new study, of which Johnson was an author, on how fructose may be a potential driver in Alzheimer’s, and they hypothesize about fructose’s potential connection to the development of other conditions.


    Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠https://levels.link/wnl⁠


    🎙 What Richard Johnson, MD, & Rob Lustig, MD, discuss:

    (09:50) — Fructose is the driver of some diseases that are on the rise in kids

    (11:53) — Fructose is a driver of obesity and metabolic syndrome

    (15:36) — Pharmaceutical treatments for Alzheimer’s disease aren’t as effective as researchers had hoped

    (17:32)— The research focus of Alzheimer’s is slowly shifting to understanding insulin resistance in the brain

    (20:41) — Is fructose a root cause of Alzheimer’s?

    (26:26) — New research suggests fructose induces a foraging response

    (28:20) — Fructose inhibits areas of the brain to encourage successful foraging

    (46:48) — We need more research on fructose

    (1:03:10) —Is fructose a factor in violence?

    ⁠Transcripts & Show notes⁠

    Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.


    Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.


    👋 WHO WE ARE:

    Levels helps you see how food affects your health. With real-time, personalized data gathered through biosensors like continuous glucose monitors (CGM), you learn which diet and lifestyle choices improve your metabolic health so you can live a longer, fuller, healthier life.


    🔗 LINKS:

    Could Alzheimer’s disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?: ⁠https://www.sciencedirect.com/science/article/abs/pii/S0002916523000047?dgcid=author⁠

    Subscribe here on YouTube: ⁠https://youtube.com/levelshealth?sub_confirmation=1⁠

    Thu, 11 Apr 2024 - 1h 07min
  • 249 - #249 - The links between gastrointestinal health, metabolic health, and fertility | Dr. Robin Rose & Ben Grynol - (Replay)

    Gastrointestinal health, metabolic health, and fertility are all linked. The gut microbiome impacts other microbiomes in the body, which can then impact the ability to conceive. Our gut microbiomes are becoming less diverse through modern farming practices and the consumption of processed foods. Dr. Robin Rose and Ben Grynol discuss how gut microbiome testing can determine underlying factors of gastrointestinal distress and the lifestyle changes that can help address symptoms and even aid fertility.


    Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠https://levels.link/wnl⁠


    🎙 WhatRobin Rose, MD, & Ben Grynol discuss:

    (08:05) — Gastrointestinal issues are associated with metabolic health issues

    (08:56) — Many people lack gut microbiome diversity

    (15:24) — Infertility in some people has links to the gut microbiome

    (30:56) — PCOS and gut dysbiosis share a connection that’s still being researched

    (32:26) — Restoring gut and metabolic health may help alleviate PCOS symptoms

    (34:44) — Metagenomic testing assesses gut health

    (39:47) — Gut health often requires balanced macronutrient intake

    (49:14) — Regenerative farming practices could help us get more quality nutrients

    (54:57) — Eliminating dairy and gluten may ease gastrointestinal symptoms

    (56:29) — Sleep quality and quantity also inform gut health

    ⁠Transcript & Show Notes⁠

    Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

    Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

    🔗 Helpful links:

    Watch the conversation: ⁠https://youtu.be/SpW9znY3fkI⁠

    Find us on YouTube: ⁠https://youtube.com/levelshealth?sub_confirmation=1⁠

    Thu, 28 Mar 2024 - 58min
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