354 - Why Agents Love Supabase
AI agents are creating more softwareâand that changes what a backend needs to do. Supabase co-founders Paul Copplestone and Ant Wilson join swyx to discuss running long-lived workloads alongside the database, making schemas easier for agents to underst...
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Mon, 26 Oct 2026
353 - How Anthropic ships the #1 LLM in the World safely: Separating the Brain from the Hands
Katelyn Lesse and Angela Jiang join Latent Space to explain the engineering behind the Claude Platform: launching Opus 5.5, separating the modelâs âbrainâ from the agentâs âhands,â scaling APIs, and building reliable managed agents. A new introduction ...
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Tue, 27 Oct 2026
352 - ⥠An Eval for AI Scientists That Knows the Answer Key - Ian Quigley, Leash Bio
Mon, 26 Oct 2026
351 - âĄïž Which GPU Clouds Are Actually Good? | ClusterMAX 3.0
Fri, 02 Oct 2026
350 - âĄïž A Worm With 302 Neurons Inspired Their Architecture â Ramin Hasani, Liquid AI
Fri, 18 Sep 2026
349 - âïž Forward Deployed: Voice AI on what works in 2026
Tue, 25 Aug 2026
348 - âĄïž Exo: Harnesses should see their own code and logs â Alex Krentsel, UC Berekeley / Google Research
Sat, 15 Aug 2026
347 - âĄïž Podcast Crossover: AIE, AGI, frontier lab strategy with â âš@matthew_bermanâ© and @swyxtv
Fri, 10 Jul 2026
346 - âĄïž The Blueprint for Autonomous Work Agents | Gavriel Cohen, NanoClaw
Mon, 29 Jun 2026
345 - âĄïž Every product of the future will be a living system â Ronak Malde, Trajectory.ai
Sun, 21 Jun 2026
344 - âĄïž Making DeepSeek v4 outperform Opus 4.7 with Taste â @AhmadAwais , CommandCode.ai
Sat, 06 Jun 2026
343 - âĄïž Google's Open AI Strategy â Omar Sanseviero, Google DeepMind
Sun, 24 May 2026
342 - âĄïž Why you should build Science Fiction â Sunil Pai, Cloudflare
Sun, 24 May 2026
341 - âĄïž Senior Dev: This "Grill Me" Prompt Is Going Viral Among Top Engineers
Thu, 07 May 2026
340 - âĄïž Competing with ChatGPT and Sierra, building a $10M ARR company â Yasser Elsaid, Founder, Chatbase
Sat, 02 May 2026
339 - âĄïž How to turn Documents into Knowledge: Graphs in Modern AI â Emil Eifrem, CEO Neo4J
Sat, 18 Apr 2026
338 - âĄïž The best engineers don't write the most code. They delete the most code. â Stay Sassy
Mon, 13 Apr 2026
337 - âĄïž Monty: the ultrafast Python interpreter by Agents for Agents â Samuel Colvin, Pydantic
Sat, 14 Mar 2026
336 - âĄïž OpenClaw's Memory Sucks and the fix is simple â Dhravya Shah, Supermemory
Mon, 09 Mar 2026
335 - âĄïž Polsia: Solo Founder Tiny Team from 0 to 1m ARR in 1 month & the future of Self-Running Companies
Sun, 01 Mar 2026
334 - âĄïž Reverse Engineering OpenAI's Training Data â Pratyush Maini, Datology
Tue, 10 Feb 2026
333 - âĄïž Context Graphs: according to the authors â Jaya Gupta, Ashu Garg, Foundation Capital
Wed, 04 Feb 2026
332 - âĄïž Prism: OpenAI's LaTeX "Cursor for Scientists" â Kevin Weil & Victor Powell, OpenAI for Science
Tue, 27 Jan 2026
331 - âĄïžÂ Building the AI Hardware Engineer with Matthias Wagner, Co-founder of Flux
Sat, 22 Nov 2025
330 - âĄïž The State of AI Engineer Hiring: Cheating, AI Adoption,Junior Devs â Vivek Ravisankar, HackerRank
Sat, 08 Nov 2025
329 - âĄïžAutomating Scientific Discovery - Jessica Rumbelow, Leap Labs
Sun, 02 Nov 2025
328 - ⥠Open Model Pretraining Masterclass â Elie Bakouch, HuggingFace SmolLM 3, FineWeb, FinePDF
Mon, 20 Oct 2025
327 - âĄïžTraversal: Causal ML and Reinforcement Learning
Sun, 05 Oct 2025
326 - âĄïžRaising $1.1b to build the fastest LLM Chips on Earth â Andrew Feldman, Cerebras
Wed, 01 Oct 2025
325 - âĄïžClaude Sonnet 4.5 and Anthropic's roadmap for Agents and Developers â Mike Krieger, Anthropic
Tue, 30 Sep 2025
324 - âĄïžSnowglobe: Simulations for your AI
Thu, 25 Sep 2025
323 - âĄïž Beyond Transformers with Power Retention
Tue, 23 Sep 2025
322 - âĄïžNo, Don't Do Palantir for AI - Brendan Falk, Hercules (AUDIO FIXED)
Thu, 18 Sep 2025
321 - âĄïžLaunching Ona: Coding Agent with Fully Sandboxed Cloud Environment
Mon, 01 Sep 2025
320 - âĄïžAccelerators @ 3x NVIDIA H200 perf, Made in the USA - Thomas Sohmers + Mitesh Agrawal, Positron AI
Mon, 18 Aug 2025
319 - âĄïžOpenCode: Claude Code but Open Source, with Any Model, and frontier TUI - with Dax Reed (@thdxr)
Tue, 05 Aug 2025
318 - âĄïžMercury: Ultra-Fast Diffusion LLMs â Estefano Ermon, CEO Inception Labs
Mon, 04 Aug 2025
317 - âĄïžComposio: 10,000+ tools that evolve for Agents â Karan Vaidya and Soham Ganatra
Mon, 04 Aug 2025
316 - âĄïžUsing RFT to Build Clinical Superintelligence
Tue, 29 Jul 2025
315 - âĄïžMath Olympiad gold medalist explains OpenAI and Google DeepMind IMO Gold Performances
Thu, 24 Jul 2025
314 - âĄïžARC-AGI-3: The Interactive Reasoning Benchmark
Fri, 18 Jul 2025
313 - âĄïžThe Future of Notebooks - with Akshay Agrawal of Marimo
Fri, 18 Jul 2025
312 - âĄïžRanking Agentic LLMs â Pratik Bhavsar, Galileo
Mon, 14 Jul 2025
311 - âĄïžAnthropic vs Cognition on Multi-Agents: A Breakdown with Dylan Davis
Sat, 05 Jul 2025
310 - âĄïžWarp 2.0: the Agentic Development Environment - Zach Lloyd and Ben Holmes
Wed, 25 Jun 2025
309 - âĄïžLaunching AI Diplomacy: the hardest LLM Game Benchmark yet - Alex Duffy
Wed, 11 Jun 2025
308 - âĄïžOpen Questions in Agentic RL â Will Brown (Prime Intellect)
Fri, 09 May 2025
307 - âĄïžFactorio Learning Environment: the ultimate Game Agent Eval â Jack Hopkins
Sun, 27 Apr 2025
306 - Why AI Compute Comes in Rectangles â Erik Bernhardsson, Modal CEO
Warm welcome to Basil Chatha, our newest cohost from the Forward Deployed side of the AI Engineering world! Weâll be ramping up a new show with him and couldnât pass up an interview with Modalâs CEO Eric on the occasion of their monster Series D! Two y...
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Thu, 22 Oct 2026
305 - The Recommendation Engine for Commodity Traders â Anekha Sokhal, Moshi
Anekha Sokhal, CEO of Moshi, joins swyx to discuss building a recommendation engine for commodity traders, turning market data into useful signals, and designing AI that fits usersâ workflows. Watch: YouTube · Moshi · Anekha 0:00 AI Engineer New York a...
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Thu, 22 Oct 2026
304 - AI for the Fortune 2000: How Tenex Builds an AI-Native SDLC â Alex Lieberman & CJ Hess
Alex Lieberman and CJ Hess join swyx at AI Engineer New York to discuss Tenexâs approach to AI-native engineering, paying for outcomes, MetaHarness, enterprise AI adoption and rebuilding SaaS. Show notes: Tenex: https://www.tenex.co/ Building an AI-nat...
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Wed, 21 Oct 2026
303 - The Programmable Data Center â Evan Conrad, SF Compute
This was recorded on the sidelines of the new Compute Trading track at AIE NYC. Catch us next at AIE CODE, our last flagship for the top agentic engineers in the world. In the early days of cloud, former guest Martin Casado made something so disruptive...
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Tue, 20 Oct 2026
302 - đŹ Lab-in-the-Loop at Compute Speed â Ian Quigley, Leash Bio
A few years ago I stumbled upon Leash Bioâs Substack, and was hooked. Be it their Kaggle competition that showed that no, we really havenât solved protein-ligand binding, or their crazy discovery that knowing a moleculeâs author is perhaps all you need...
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Wed, 14 Oct 2026
301 - Dyna-2: General Purpose Physical Agents with Hour-Long Autonomy â Jason Ma, Dyna Robotics
Watch along AIE NYC and join us at AIE CODE in SF next month! This episode includes a live demo of the Taku robot that is best enjoyed on YouTube. Last month, Dyna made waves by announcing Dyna-2, a world-action model pre-trained on one million hours o...
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Tue, 13 Oct 2026
300 - đŹ Why AlphaFold Didn't Solve Protein Folding â Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub
From the Bitter Lesson of AI scaling to the unsolved mysteries of protein folding, Google DeepMindâs Pushmeet Kohli and Biohubâs Sal Candido are rethinking what it takes to build AI that truly understands biology. In this special panel moderated by Bra...
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Sat, 10 Oct 2026
299 - đŹ Synthesis Superintelligence: from Semiconductors to Superconductors â Periodic Labsâ Liam Fedus and Ekin Dogus Cubuk
Itâs hard to believe that Periodic was only launched last September: One year later, it is considered one of the pre-eminent AI scientist labs, with dizzying talent density and astonishing progress in the autonomous lab buildout: Most people are famili...
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Thu, 08 Oct 2026
298 - Academia is for Ambition â Alex Zhang, MIT
Last call for regular tickets for AI Engineer NYC! As an exclusive for Latent Space subscribers, the first 30 of you can take a 30% off code if it helps - for new tickets only, no refunds! See you in 2 weeks! While we tend to cover industry on the pod,...
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Fri, 02 Oct 2026
297 - Why Dwarkesh is Wrong about Computer Use + How OpenAI shipped its Jev competitor in 1 Week
Three months ago Dwarkesh, who has been posting incredible blogs and episodes about RL, posted a framing question for his video essay on RLVR which upset a lot of Computer Use folks: We are no strangers to learning in public and are no strangers to the...
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Wed, 30 Sep 2026
296 - Claude Codeâs Next Era â Thariq Shihipar, Anthropic
We are excited to have Anthropic share their latest AI x Finance work at AI Engineer New York ( https://ai.engineer/nyc/2026 ), coming up in 2 weeks! In case youâve been under a rock, hereâs a non-exhaustive list of what Anthropic has been shipping sin...
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Tue, 29 Sep 2026
295 - OpenRouter: from Seed to Stripe â with OpenRouterâs Alex Atallah & AMPâs Anjney Midha
From the earliest days of open-weight models to becoming the neutral routing layer for more than 10 million developers, OpenRouter is one of the clearest bets that the future of AI will be multi-model. In this episode, OpenRouter co-founder & CEO Alex ...
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Fri, 25 Sep 2026
294 - Runwayâs WorldPrompt and the Engineering of Real-Time Worlds
Earlier this month, world model company Runway introduced GWM Worlds 2, a research preview that âturns high-fidelity video and audio generation into real-time interactive simulation.â Runway calls this an âautoregressive diffusionâ model; with autoregr...
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Fri, 25 Sep 2026
293 - đŹ Bio-security is an AI Arms Race - Eric Nguyen (CEO, Radical Numerics)
The OpenAI â Hugging Face attack has people asking âwhat else do we need to worry about?â and Anthropicâs filters flag two things: cyber-security and biology. The natural question is: what about bio-security, then? Clem Delangue argues that cyber-warfa...
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Wed, 23 Sep 2026
292 - đŹ An Oscar, Two Asteroids, and the Algorithm in Your sklearn: John Platt on AI for Science
How often do you get to talk to a guest who has both an Academy Award and who invented textbook machine learning algorithms? John Platt has an Oscar, two textbook algorithms, two named asteroids, and an Erdos-Bacon number of 6. This was easily the most...
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Tue, 22 Sep 2026
291 - Jev: System One models for Prod, not God â with Diogo Almeida, CEO, TypeSafe AI
Tickets for AIE NYC now open, and apply for the invite-only AIE CODE. Join us! We have an unusual relationship with todayâs guest: for years since coauthoring the InstructGPT paper, Diogo Almeida had been saying that API-available frontier models have ...
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Mon, 21 Sep 2026
290 - Underwriting Superintelligence: Backing Agents you can Sue â Rune Kvist, AIUC
AIUC first got our attention with the NFDG backing, and have just announced a $40M series A today, with the most impressive industry advisor list we may have ever seen for an early startup behind AIUC-1, their agent standard backed by real insurance: F...
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Wed, 16 Sep 2026
289 - Humanityâs Last Invention â Richard Socher of Recursive
At 1:09:00 we talk about the rise of AI x Finance, and AIE NYC is one month away - our hotel block is 97% sold out, get tix & travel ASAP - we will announce speakers from Bridgewater, Ramp, Coatue, Mastercard, Vanguard, Coinbase, Blackrock, Fidelity, P...
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Mon, 14 Sep 2026
288 - đŹ âWe have foundation models for language, not for physicsâ â Anima Anandkumar, Bren Professor of Computing
A few years ago, Caltech Prof. and co-founder of Accelerated Understanding, Anima Anandkumar set out to develop the first open-source weather model with AI. Talking to experts in the field, she was met with skepticism. Weather is chaotic, physics simul...
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Wed, 26 Aug 2026
287 - Simulation: the new Scaling Law â Joon Sung Park, Simile AI
When we first dicsussed the Summer of Simulative AI in 2024 we knew it would be a brief summer, but it has recently come back with a vengeance with SimGym in April and now Simile AIâs $2B Series B, backed by GreenOaks and Index Ventures with prominent ...
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Fri, 21 Aug 2026
286 - đŹ The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery
This January, four big AI Ă Pharma tools deals were announced at the huge JPM Pharma conference that takes over San Francisco every year. OpenAI-backed Chai Discovery (now worth $4B) was somehow at the heart despite being all of 2 years old. The Scienc...
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Tue, 11 Aug 2026
285 - The Inference Engineering Masterclass â Philip Kiely & Ali Taha, Baseten
Watch the full episode on YouTube: We first covered Baseten last year when DeepSeek mania was at peak hype. Now they have raised a monster $13B round and become one of the new cohort of AI Infra decacorns that are (with Nvidia, Intel, and the semis com...
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Mon, 03 Aug 2026
284 - Codex from 0 to 10M Users: Building ChatGPT Work â Akshay Nathan, OpenAI
There are roughly 100x more people who use code than who can write code. As code that âjust worksâ becomes easier to generate, this group may be the biggest prize of all â if you can get the agentic interface right. A key trend we have been tracking ov...
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Tue, 28 Jul 2026
283 - Inside the Model Factory â Eiso Kant, Poolside AI
In recent months, the open vs closed, and US vs China discussions on model ownership and sovereign/local AI have heated up to a fever pitch. So it is very very good news that Poolside AI are finally emerging with new models, like Laguna S 2.1, that are...
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Thu, 23 Jul 2026
282 - đŹ Causal Models Need Causal Data - Xairaâs X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)
Bet on information If test loss flatlines after 1.5B parameters while training loss continues to drop as you scale, that tells you that your model is limited by the amount of information in your data. Training on a single, smallish data set exposed an ...
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Tue, 21 Jul 2026
281 - đŹ The Lab of the Future Should Feel Like a Data Center â Andy Beam & Rafa GĂłmez-Bombarelli, Lila Sciences
Imagine a dark warehouse. Racks and racks of devices with wires, tubes, and electronics sticking out. The next AI data center? No. This is Lila Sciences â dream for the future of science. A dark warehouse full of AI-guided robotics and lab equipment, c...
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Thu, 16 Jul 2026
280 - Why AI Infrastructure must evolve for Agent Experience â Akshat Bubna, Modal CTO
Weâve been running a bit of an Agent Cloud series surveying all the top inference/compute/cloud providers, from Databricks to Daytona to Railway and, even further back, E2B, but weâre excited to conclude this series returning to Modal, which has just r...
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Wed, 08 Jul 2026
279 - đŹ The Coolest Diffusion Research Isn't in LLMs â Evan Feinberg & Sergey Edunov, Genesis Molecular AI
This episode has a fun personal twist: Thereâs a counterfactual world where I was employee #1 at Genesis Molecular AI, the company behind todayâs episode. A certain introduction happened a few weeks too late and I had already happily signed at Atomwise...
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Wed, 01 Jul 2026
278 - Why the Frontier Ecosystem must be Open â Matei Zaharia and Reynold Xin, Databricks
Weâre excited to have Databricks join us at AIEWF, among hundreds of the top companies in the AI Engineer ecosystem. LS subscribers can use their discount to get past the late bird pricing and access over $50k in sponsor offers! Everyone is still talki...
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Wed, 24 Jun 2026
277 - Red-Teaming after Mythos â Zico Kolter & Matt Fredrikson, Gray Swan
AI Engineer Worldâs Fair regular bird tix will sell out ~today! Join us next week ahead of the Late Bird price hike and get >$40,000 in sponsor credits for attending! Thanks to the US Government issuing an export control directive on Mythos and Fable, ...
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Mon, 22 Jun 2026
276 - The Professor of Outputmaxxing â Anjney Midha, AMP
Last 4 days before regular tickets sell out at AI Engineer Worldâs Fair - this is the single biggest gathering of AI Engineers, Founders, Leaders, and Researchers in the world. Attendees get >$5000 worth of sponsor credits and talk tracks are looking F...
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Thu, 18 Jun 2026
275 - đŹ The Self-Driving Lab â Joseph Krause, Radical AI
On the Science pod, weâve been covering a lot of the ground on how AI is revolutionizing STEM, but one of our favorite off the record topics since our launch is which field is harder to accelerate: math, bio, or physics? Today weâre back in Materials S...
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Wed, 17 Jun 2026
274 - Reality: The Final Eval â Lukas Petersson and Axel Backlund of Andon Labs
The new AIEWF website is live! Get your tickets booked ASAP as they -will- sell out. Take the AI Engineering Survey and get >$2k in credits and free AIE WF tickets! Most industry benchmarks compress intelligence and reasoning ability into scores. SWE-B...
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Thu, 04 Jun 2026
273 - đŹ Scaling Past Informal AI - Carina Hong, Axiom Math
In 2025, seven-month-old startup Axiom solved all 12 of the problems Putnam exam (scoring 8/12 in the time limit) a prestigious undergraduate math exam. The 12/12 score is better than the top undergraduates (110/120) and the closest AI system that repo...
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Wed, 03 Jun 2026
272 - âĄïž Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build
Weâve informally heard that Satya is a listener to LS for a couple years now, but it was still absolutely surreal to meet him and do a live pod at Build, together with our friends at No Priors, the leading VC AI Podcast that we also greatly admire! We ...
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Wed, 03 Jun 2026
271 - GitHub's plan for Agents â Kyle Daigle, GitHub
Iâm excited to work with Microsoft once again as the presenting sponsors of the AI Engineer Worldâs Fair! Weâll streaming live from MS Build today for a special crossover pod with our friends at No Priors and the one and only Satya Nadella. However we ...
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Tue, 02 Jun 2026
270 - Why Video Agent models are next â Ethan He, xAI Grok Imagine
Weâre announcing AIEWF speakers this week! Take the AI Engineering Survey! Todayâs guest Ethan first joined us for the LS Paper Club as the lead on NVIDIA Cosmos World Model, but then joined xAI and built Grok Imagine in 3 months: He comes back on Late...
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Mon, 01 Jun 2026
269 - The Age of Async Agents â Cognition's Walden Yan & OpenInspect's Cole Murray
The new AIEWF website is live! CFPs close in 2 days and we will run our first New Engineer Orientation this weekend, get your tickets booked ASAP as they -will- sell out. Take the AI Engineering Survey and get >$2k in credits and free AIE WF tickets! O...
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Thu, 28 May 2026
268 - đŹ ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
Editorâs note: In our first BioHub pod with Priscilla and Mark they discussed their acquisition of EvoScale, led by Alex Rives, who is now Head of Science at BioHub. With ESM-1 they trained language models on millions of protein sequences drawn from ac...
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Wed, 27 May 2026
267 - Giving Agents Computers â Ivan Burazin, Daytona
Take the 2026 AI Engineering Survey and get >$2k in credits and AIE WF tickets! On the product side, everyone is getting Computer - Perplexity, Manus, Cursor, and so on. Meanwhile on the research side, agentic evals like TerminalBench and GDPVal are al...
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Thu, 21 May 2026
266 - Railway: The Agent-Native Cloud â Jake Cooper
Take the 2026 AI Engineering Survey and get >$2k in credits and AIE WF tickets! This was recorded before Railway suffered a major GCP outage on May 19, despite being a multi-AZ, multi-zone mesh ring, with HA fiber interconnects between their Metal <> G...
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Wed, 20 May 2026
265 - đŹ The Autonomous Drone Tech Stack & Economics of Drones â Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion
The future of war has been evolving before our eyes in Ukraine, yet the west still plans to fight the last war. In this special episode, guest host Noah Smith (@noahpinion) and Brandon Anderson sit down with Yaroslav Azhnyuk (@YaroslavAzhnyuk), a seria...
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Mon, 18 May 2026
264 - AI-Native Healthcare: 100M Doctor Visits, 10â20 Hours Saved, Prior Auth in Minutes â Janie Lee & Chai Asawa, Abridge
Special discounts up for AIE Melbourne (LS discount) and AIE Worldâs Fair (group discounts up to 25% - CFPs still open for Autoresearch and Vertical AI) Cya there! Abridge did not start as an âGPT wrapperâ. It was founded in 2018, years before the Camb...
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Thu, 14 May 2026
263 - đŹ Doing Vibe Physics â Alex Lupsasca, OpenAI
Some people are going crazy over GPT 5.5. Some people. This is the story of the Jagged Frontier. People who use AI to write emails or even code implementation work find the lift moderate whereas people pushing the limits of the model are figuring out t...
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Tue, 05 May 2026
262 - Physical AI that Moves the World â Qasar Younis & Peter Ludwig, Applied Intuition
From building Applied Intuition from YC-era autonomy tooling into a $15B physical AI company, Qasar Younis and Peter Ludwig have spent the last decade living through the full arc of autonomy: from simulation and data infrastructure for robotaxi compani...
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Mon, 27 Apr 2026
261 - AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026)
Today, we check in a year after the first Unsupervised Learning x Latent Space Crossover special to discuss everything that has changed (there is a lot) in the world of AI. This episode was recorded just after AIE Europe, but before the Cursor-xAI deal...
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Thu, 23 Apr 2026
260 - Shopifyâs AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym â with Mikhail Parakhin, Shopify CTO
Early bird discounts for the San Francisco Worldâs Fair, the biggest AIE gathering of the year, end today - prices will go up by ~$500 tonight so do please lock in ASAP! From near-universal AI tool adoption inside Shopify to internal systems for ML exp...
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Wed, 22 Apr 2026
259 - đŹ Training Transformers to solve 95% failure rate of Cancer Trials â Ron Alfa & Daniel Bear, Noetik
Today, we explain this piece of âclickbaitâ from our guest! TL;DR: 95% of cancer treatments fail to pass clinical trials, but it may be a matching problem â if we better understood what patients have which tumors which will respond to which treatments,...
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Mon, 20 Apr 2026
258 - Notionâs Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future â Simon Last & Sarah Sachs of Notion
For all those who missed out on London, see you in Miami next week! Notion, the knowledge work decacorn, has been building AI tooling since before ChatGPT, with many hits from Q&A in 2023 and unified AI in 2024 and Meeting Notes in 2025. At the end of ...
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Wed, 15 Apr 2026
257 - Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review â Ryan Lopopolo, OpenAI Frontier & Symphony
Weâre proud to release this ahead of Ryanâs keynote at AIE Europe. Hit the bell, get notified when it is live! Attendees: come prepped for Ryanâs AMA with Vibhu after. Move over, context engineering. Now itâs time for Harness engineering and the age of...
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Tue, 07 Apr 2026
256 - Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different"
Fresh off raising a monster $15B, Marc Andreessen has lived through multiple computing platform shifts firsthand, from Mosaic and Netscape to cofounding A16z. In this episode, Marc joins swyx and Alessio in a16zâs legendary Sand Hill Road office to arg...
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Fri, 03 Apr 2026
255 - Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient â with Chris Manning and Fan-yun Sun
Weâve been on a bit of a mini World Models series over the last quarter: from introducing the topic with Yi Tay, to exploring Marble with World Labsâ Fei-Fei Li and Justin Johnson, to previewing World Models learned from massive gaming datasets with Ge...
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Thu, 02 Apr 2026
El Partidazo de COPE COPE
