The Metabolic Link

What happens to nutrition science after the study is published? Dr. Maya Maroto, EdD, MPH, RD, is Executive Director of the Coalition for Metabolic Health. A registered dietitian and certified ketogenic nutrition specialist, she has worked in academia, in nutrition policy and communications at the FDA and USDA, and on the food industry side at FoodMinds. Her own turn toward carbohydrate restriction began when a loved one with type 2 diabetes did not improve on the conventional advice she had...

What would an emergency physician tell his patients if he could have met them 20 years before their crisis? Dr. Michael Doney, MD, MPH, MS, spent years as a board-certified emergency physician managing the acute consequences of chronic disease. Today he is Executive Medical Director of Biograph, a preventive health clinic that combines whole-body MRI, cardiovascular imaging, DEXA, VO2 max testing, movement analysis, blood work, and genetics with a team of physicians, registered dietitians, e...

Join us for a FREE live Q&A with Dr. Boz on October 14 at 9:00 AM PT / 12:00 PM ET and ask her your questions directly. No membership required. Register here. What happens when an internist teaches ketogenic nutrition to 200 students at the same time and tracks every one of their glucose and ketone readings on shared dashboards? Dr. Annette Bosworth, MD, known to her audience as Dr. Boz, is an internal medicine physician and the author of ANYWAY YOU CAN and ketoCONTINUUM. After leaving ...

Join us for a FREE live Q&A with Dr. Salcedo on September 10 at 9:00 AM PT / 12:00 PM ET and ask her your questions directly. Register here. What if the uterus is an end organ, responding to insulin and inflammation the same way the heart, kidneys, and liver do? Dr. Andréa Salcedo is a board-certified OBGYN (DO, MPH, FACOG) and associate professor at Loma Linda University School of Medicine whose research and clinical practice, which she calls conscious gynecology, examine gynecologic dis...

Today we are doing something we have never done before. Once a month, members of The Metabolic Initiative get an hour to put their own questions directly to the scientists and clinicians at the forefront of metabolic health. Those sessions stay inside the platform. This one does not. After Dr. Ben Bikman joined us for episode 100, the questions kept coming. So we invited him back to sit with Dr. Dominic D'Agostino and MHI co-founder Victoria Field for a live member Q&A, and for the first ...

Ketogenic and low-carbohydrate diets often focus on a specific carbohydrate target: keep your net carbs under 30 grams. But as registered dietitian and certified diabetes educator Franziska Spritzler demonstrates in this presentation from Metabolic Health Summit, a carbohydrate target is not a therapy. Effective implementation means a full assessment of medical history, medications, labs, food preferences, lifestyle, and the motivation that will carry a patient through year one and beyond. Sp...

Join us for a live Q&A with Dr. Ben Bikman here. For the 100th episode of The Metabolic Link, Ben Bikman, PhD, professor of cell biology and physiology at Brigham Young University and author of Why We Get Sick, returns for a milestone conversation with co-hosts Dominic D’Agostino, PhD, and Victoria Field. Together, they examine what clinicians are measuring, what conventional approaches may be missing, and how the science of metabolic health continues to evolve. Bikman argues that the cl...

What can 21 days of continuous glucose and ketone data, recorded during a 1,000-mile cycling journey, reveal about managing type 1 diabetes on a ketogenic diet? Dr. Ian Lake is a UK-based primary care physician who has lived with type 1 diabetes for more than 30 years. After two decades of conventional high-carbohydrate management, he adopted a very low-carbohydrate, ketogenic approach and began examining insulin not simply as a glucose-lowering medication, but as a metabolic hormone whose re...

Attend a Live Q&A with Dr. Glandt. Reigster here. What if the way we treat type 2 diabetes is fundamentally backwards? Dr. Mariela Glandt is an endocrinologist and obesity medicine specialist who spent 15 years practicing conventional medicine before concluding, in her words, that how we treat diabetes “is actually upside down.” As co-founder of OwnaHealth, she focuses on addressing the insulin resistance underlying type 2 diabetes, not only the elevated blood sugar it eventually causes. ...

Fewer than 40% of people with PTSD respond to standard care. For the intrusive symptoms at the core of the disorder, response rates may be lower than 15%. So what options remain for patients who have not responded to existing treatments? Dr. Keren Doenyas-Barak, director of the PTSD program at the Sagol Center for Hyperbaric Medicine and Research and a faculty member at Tel Aviv University, has treated close to 1,000 civilian and military patients and led sham-controlled trials that are helpi...

Dr. Paul Reynolds has spent his career studying what he calls “two heads of the same beast”: inflammation and glycation — two interlocking processes that may help explain why so many chronic diseases are connected, even when they are treated as separate conditions. Dr. Reynolds is a professor and research scientist at Brigham Young University whose NIH-funded research program studies inflammation, lung biology, glycation, and the AGE/RAGE receptor system that links metabolic and environmental...

In people with severe depression and cognitive decline, brain glucose metabolism has been shown in some studies to decline measurably. Ketone metabolism, by contrast, appears relatively preserved. That single observation is reshaping how researchers think about psychiatric illness. In this episode, Dominic D'Agostino sits down with Bret Scher, a cardiologist who pivoted to metabolic psychiatry and now leads clinical education and content for Metabolic Mind at the Baszucki Group. Dr. Scher bri...

A gene mutation that reduces ketone production in the fasted state is associated with sudden infant death in modern populations. But in the ancestral context where it evolved alongside an omega-3-rich diet, it may have been part of what kept infants alive. Dr. Gideon Mailer and Nicola Hale join The Metabolic Link to present their hypothesis that the CPT1A L479 Arctic variant is not anti-ketogenic but pro-metabolic flexibility, conserving glucose by upregulating ketosis at the fed-state thresh...

In a 12-week clinical trial at The Ohio State University, every woman with PCOS who completed the intervention experienced a change in her menstrual status. One participant, who had never had a period in her life, began menstruating within a week. Another saw spotting after five years of amenorrhea while taking only a ketone supplement without adopting a ketogenic diet. These are among the earliest controlled findings linking ketogenic interventions directly to reproductive hormone restoratio...

A veteran walks into the clinic with a persistent migraine. Four minutes of vagal nerve stimulation later, the migraine is gone. This is not a one-off result. It is what Dr. Michael Hoffman has been observing for over seven years in the VA hospital system, using non-invasive devices he considers severely underutilized. Dr. Hoffman is a stroke and cognitive-behavioral neurologist who trained at Columbia University, spent 14 years in the VA system, and has evaluated an estimated 10,000 stroke ...

You could have elevated levels of contaminants like uranium or arsenic in your drinking water—and not know it. Many of these compounds are colorless, odorless, and undetectable without testing. Johnny Pujol is a water chemist and the founder of Tap Score, a drinking water testing platform supported by a network of roughly 270 specialized laboratories. His path from electrochemistry research to consumer water testing was driven by a simple realization: the chemistry inside what looks like a cl...

Register for a live Q&A with Dr. Tommy Wood on Wednesday, March 25th. Decreased glucose uptake in the brain is often considered a hallmark of Alzheimer's disease. But Dr. Tommy Wood asks whether part of that metabolic signature may reflect how little cognitive demand we place on the brain. He sits down with Dr. Dominic D'Agostino for a nuanced conversation on metabolic health and cognitive function.. Dr. Wood is a neuroscientist, neonatal brain injury researcher, and author of The Stimula...

Get free access to our new Ketogenic Metabolic Therapy ebook here. Could changing your metabolism reduce alcohol cravings, ease psychiatric symptoms, and even make cancer immunotherapy more effective? The science is pointing to yes, and the mechanisms are fascinating. In this Journal Club episode, co-hosts Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff break down five peer-reviewed papers from their newly released Ketogenic Metabolic Therapy ebook (Volume 4). From a French precli...

Dr. Mark Tarnopolsky's VO2 max was once 87.6 ml/kg/min — an elite-level mark few humans have reached. He's competed at three world championships in three different sports. He's also had three cardiac ablation surgeries, bled from his bowels after races, and watched his vision tunnel to a speck crossing a finish line. His story is a master class in where the line falls between peak performance and self-destruction. Now 63, Tarnopolsky is a neurologist, neuromuscular disease specialist, and sup...

Roughly 90% of Alzheimer's patients develop neuropsychiatric symptoms including anxiety, persistent fear, and an inability to recognize safety — but little research is being done to investigate why. New data connecting PTSD, trauma, and accelerated brain aging may hold the answer. Dr. Caesar Hernandez is a behavioral, molecular, and circuit neuroscientist and assistant professor in the Division of Gerontology, Geriatrics & Palliative Care at the University of Alabama at Birmingham. His re...

What if the sequence we've always assumed—plaque causes arterial stiffness—is actually backwards? Dr. Lily Johnston proposes that impaired nitric oxide signaling may stiffen arteries first, creating the endothelial injury that then promotes plaque formation. Dr. Lily Johnston is a board-certified vascular surgeon and newly certified obesity medicine physician who bridges the operating room and metabolic medicine. After years of scraping plaque from arterial walls, she began questioning why su...

The term “ultra-processed food” appeared nearly 100 times in the White House’s Make America Healthy Again report. But questions remain about whether the concept is precise enough to guide effective policy. Dr. David Ludwig—Harvard endocrinologist, obesity researcher, and author of Always Hungry—joins Dr. Dominic D'Agostino to dismantle the ultra-processed food framework from the inside out. Ludwig reveals why the NOVA classification system lumps protein bars with soda, why the FDA admitted th...

Glioblastoma has a long-term survival rate under 1% at ten years. After decades of research focusing primarily on mutation-targeted therapies, median survival has improved by only a few months. Dr. Tomás Duraj believes there's a better path forward. Dr. Duraj is a physician-scientist at Boston College working on the metabolic vulnerabilities of cancer. In this Metabolic Health Summit presentation, he outlines a clinical framework for studying ketogenic metabolic therapy — one built on biomark...

After 20+ years treating cancer patients, Dr. Christy Kesslering started asking a question her colleagues weren't asking: why are so many of my breast cancer patients metabolically sick — even when they're not obese? That question changed everything. Dr. Kesslering is a classically-trained radiation oncologist, metabolic health practitioner, and terrain theorist. She spent two decades practicing oncology in the Chicagoland area before transitioning to focus full-time on what she believes is...

A patient arrives at shock trauma with flesh-eating bacteria, limbs appearing unsalvageable. Hours later, after treatment in a massive submarine-like chamber, those same limbs show signs of recovery. This pivotal moment launched Dr. Scott Sherr's journey into the world of hyperbaric oxygen therapy and its untapped potential for metabolic healing. Victoria Field welcomes Dr. Scott Sherr, a board certified internal medicine physician who transformed his practice after witnessing HBOT's dramatic...

What if the key to treating neurodegenerative diseases lies not in attacking symptoms, but in healing mitochondria? Dr. Matthew Phillips, a neurologist who coined the term "metabolic neurologist," shares groundbreaking insights from his decade-long journey implementing ketogenic diets and fasting protocols for Parkinson's, Alzheimer's, and glioblastoma patients. In this episode, Dr. Phillips reveals his clinical framework combining metabolic therapies with standard of care, his current gliobl...

For over fifty years, Americans have been told that cutting fat was the key to better health. Yet after decades of low-fat guidelines, rates of obesity, diabetes, and metabolic dysfunction have skyrocketed - now affecting more than 88% of the population. In this episode of The Metabolic Link, Victoria Field sits down with Dr. Nina Teicholz, science journalist and author of The Big Fat Surprise, whose decade-long investigation into nutrition science uncovered how flawed evidence and policy dec...

When veterinarian Dr. Loren Nations lost his wife to aggressive cancer despite the best conventional treatments, he didn't just grieve—he revolutionized his entire approach to medicine. In this deeply personal conversation, Dr. Nations reveals how tragedy led him to discover that our pets are experiencing metabolic disease at rates even higher than humans, with 61% of cats and 59% of dogs now obese. Dr. Loren Nations is a board-certified veterinarian with over 30 years of experience. He's the...

What if the food you eat could change the way you breathe at night? In this episode, recorded live at The Metabolic Health Summit, Dr. Jonathan Jun reveals how metabolism and sleep-disordered breathing are deeply connected, and why shifting from carbs to fat might improve more than just your waistline. Dr. Jonathan Jun, a leading researcher on obesity hypoventilation syndrome (OHS) and obstructive sleep apnea (OSA), walks us through the groundbreaking KETOHS trial, where a ketogenic diet was ...

Could treating food like a drug be the breakthrough we've needed in food addiction treatment? In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Tro Kalayjian - physician, researcher, and former obesity patient - to explore whether food addiction should be classified as a true addiction, and how his TOWARD model is helping patients overcome binge eating and food-related compulsions. Dr. Tro shares findings from his recent peer-reviewed paper, TOWARD: a Metabolic ...

Muscle isn’t just about strength or performance — it’s metabolic armor. In this episode of The Metabolic Link, Dr. Andy Galpin sits down with hosts Victoria Field and Dr. Dominic D’Agostino to show how muscle, cardio fitness, and bone density work together to protect against decline and extend healthspan. From women’s training and recovery practices to kids in the weight room, Dr. Galpin translates decades of research into practical strategies anyone can use. Big questions Dr. Galpin helps an...

Plastic surgery meets metabolic medicine. Dr. Cameron Chesnut isn't just changing faces - he's changing the entire surgical process. In this episode, Dr. Dominic D'Agostino talks with the facial plastic surgeon who’s using ketones, hyperbaric oxygen, red light, and regenerative protocols to optimize brain health, accelerate recovery, and eliminate opioids entirely. Trusted by high performers around the world, Dr. Chesnut is known for delivering natural, rejuvenated, and seemingly untouched ...

Did you know that over 7 million Americans live with Alzheimer’s—and that number is expected to nearly double by 2050? Despite decades of research and billions spent, most treatments only offer minimal slowing of symptoms. But what if we’ve been approaching this disease all wrong? In this powerful episode of The Metabolic Link, host Victoria Field sits down with renowned neurologist, researcher, and bestselling author Dr. Dale Bredesen. He shares how Alzheimer’s isn’t caused by one thing—and ...

👉 Register for a LIVE Q&A with Dr. Bellamy on August 19th at 8am PT / 11am ET at https://membership.metabolicinitiative.com/bellamy Can metabolic therapy play a transformative role in the treatment of serious mental illness? In this episode of The Metabolic Link, host Victoria Field speaks with Dr. Erin Bellamy - a Chartered Psychologist, Metabolic Psychiatry Practitioner, and CEO of IKRT - about the clinical application of ketogenic metabolic therapy (KMT) for psychiatric disorders. Wi...

For more exclusive content on metabolic health, including additional videos with Dr. Andrew Koutnik, check out our membership platform for free here! Despite incredible advances in diabetes technology, blood sugar control in people with Type 1 diabetes hasn’t meaningfully improved in over a decade. In this eye-opening episode recorded live at Metabolic Health Summit, Dr. Andrew Koutnik - a scientist, patient, and advocate - dives into the science behind this paradox. Dr. Koutnik shares ground...

For more exclusive content on metabolic health and therapy, check out our membership platform for free: https://membership.metabolicinitiative.com In this Journal Club edition of The Metabolic Link, hosts - Victoria Field, Dr. Dominic D’Agostino, and Dr. Angela Poff dissect two powerful papers reshaping our understanding of metabolic health. First up: a striking human study showing that exposure to sugar rationing during the first 1,000 days of life reduced the risk of type 2 diabetes and hy...

What’s really causing America’s obesity epidemic? In this special debate episode of The Metabolic Link, two leading voices in metabolic health square off: Dr. Richard Johnson, renowned for his research on fructose metabolism, and Dr. Layne Norton, a PhD in nutritional sciences and expert on the energy balance model. Moderated by host Dr. Dominic D’Agostino, the discussion dives deep into the biological roots of obesity, the relevance of sugar-sweetened beverages, the role of leptin and...

Join us for a Live Q&A on June 18th at 9am PT/12pm ET with Dr. Anthony Chaffee and also enjoy ad-free exclusive episodes, videos covering the latest science on metabolic health on therapy, and earn CMEs by clicking here. In this episode, Dr. Anthony Chaffee—medical doctor, neurosurgical registrar, and nutrition educator—joins Dr. Dominic D’Agostino for a thoughtful exploration of the scientific rationale behind animal-based ketogenic diets. Together, they discuss burgeoning interest ...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health and therapy, and earn CMEs here! In this deeply personal and courageous episode of The Metabolic Link, we hear from patient advocate and podcast co-host Matt Baszucki, who shares how he endured—and ultimately overcame—type 1 bipolar disorder through a radical shift in treatment: ketogenic metabolic therapy. After years of hospitalizations, debilitating mood episodes, and faile...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here! If you’re a clinician, scientist, or anyone interested in taking a deep dive into the complexities of hormone regulation, this episode of The Metabolic Link Podcast is for you! Recorded live at Metabolic Health Summit 2024, this in-depth presentation by Dr. Kyle Gillett—dual board-certified in family and obesity medicine—dives deep into the biochemical, cl...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.com In today's journal club episode, co-hosts of The Metabolic Link, Dr. Angela Poff and Dr. Dominic D'Agostino, unpack the startling rise of non-alcoholic fatty liver disease (NAFLD)—a silent epidemic affecting millions worldwide. Tune in as they break down groundbreaking new research revealing how NAFLD isn't just impacti...

Join us for a FREE Live Q&A with Dr. Spencer Nadolsky on April 22nd at 9am PT / 12pm ET! Your first seven days are free, and as a member of The Metabolic Initiative, you’ll gain access to exclusive, ad-free episodes, hundreds of expert-led videos on metabolic health and therapy, CME opportunities, and more here! In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Spencer Nadolsky—board-certified obesity and lipid specialist, former NCAA heavyweight wrestler, a...

Join us for a Live Q&A with Dr. Ovadia on March 31st at 12 PM PT / 3 PM ET! Your first seven days are free, and as a member of The Metabolic Initiative, you’ll gain access to exclusive, ad-free episodes, hundreds of videos on metabolic health (including Dr. Ovadia’s presentation, Fanning the Flames: Inflammation, Insulin Resistance, and Heart Disease), CME opportunities, and more. Register here! Dr. Philip Ovadia is a cardiac surgeon on a mission to change how we think about heart diseas...

Mitochondria do more than power our cells—they may hold the key to understanding and treating mental illness. In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Ana Andreazza, a leading expert in mitochondrial health at the University of Toronto. Dr. Andreazza has pioneered research linking mitochondrial dysfunction to psychiatric disorders like bipolar disorder, utilizing groundbreaking 3D brain organoid models to study neurotransmission. She also leads resear...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here. What’s the best way to optimize metabolic health? In this powerhouse episode of The Metabolic Link, we bring together leading experts including Dr. Ben Bikman, Dr. Richard Johnson, Dr. Jonathan Jun, Dr. Nick Norwitz, and Dave Feldman from our Optimizing Metabolic Health Symposium filmed at Metabolic Health Summit 2024 and hosted by Dr. Dominic D'Agostino. ...

What if we could target cancer at its metabolic core? In this episode of The Metabolic Link, Dr. Dominic D’Agostino is joined by Dr. Tomás Duraj, a physician and cancer metabolism researcher working alongside Dr. Thomas Seyfried. Dr. Duraj is the lead author of a groundbreaking review on ketogenic metabolic therapy for glioblastoma, bringing together leading experts to explore how metabolic strategies could reshape cancer treatment. In this deep-dive conversation, they discuss the bioenergeti...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.com Can a ketogenic diet revolutionize the management of type 1 diabetes? In this episode of The Metabolic Link, Dr. Ian Lake, a UK-based physician and type 1 diabetes advocate, shares his personal and professional journey in using low-carb and ketogenic diets to improve metabolic control. Diagnosed with type 1 diabetes ...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, watch 100s of videos on metabolic health, and earn CMEs here. In this powerful and unfiltered episode of The Metabolic Link, we're sharing a full presentation by Chad Vanags, a former SaaS executive and entrepreneur who has turned his stage 4 lung cancer diagnosis into a mission to reshape the way we think about healing. Recorded live at Metabolic Health Summit in January of 2024, Chad shares his journey of bec...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here. In this journal club episode, host Victoria Field is joined by Dr. Angela Poff and Dr. Dominic D’Agostino to dive into two groundbreaking studies shaping our understanding of metabolism and its role in health and disease. The team explores the nuances of a recent randomized controlled trial on ketogenic diets, free sugar restriction, and their effects on glucose tolerance, lipid metabolism, ...

Join our free Live Q&A with Lauren on December 18th and become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Register here! In this episode of The Metabolic Link, host Victoria Field sits down with Lauren Kennedy West, a passionate mental health advocate and social worker who was diagnosed with schizoaffective disorder in 2016. Lauren reveals her extraordinary journey of using metabolic therapy to not only manage but reverse debilitating symptom...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.com In this special episode of The Metabolic Link, we’re sharing an exclusive panel discussion from Metabolic Health Summit 2024, where leading experts dive into the science and real-world applications of allulose, a natural low-calorie sweetener with potential metabolic health benefits. Featuring insights from Dr. Richard Johnson, Dr. Jeff Volek, Dr. Ben Bik...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Your first 7 days are free! PLUS use code blackfriday at checkout to receive 50% off your first 3 months (through November 29th): https://membership.metabolicinitiative.com In this episode of The Metabolic Link filmed at Metabolic Health Summit 2024, Dr. Valter Longo shares his latest research on the fasting mimicking diet (FMD) and its powerful impact on aging, metabolic diseases, and cancer tre...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Your first 7 days are free! PLUS use code blackfriday at checkout to receive 50% off your first 3 months (through November 29th): https://membership.metabolicinitiative.com In this episode of the Metabolic Link podcast, we are joined by Beth Zupec-Kania, an experienced dietitian and nutritionist with over 30 years in the field of ketogenic metabolic therapy. Beth has played a pivotal role in the d...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.com In this episode, we're sharing a presentation from Metabolic Health Summit 2024 that dives into a groundbreaking experiment titled "Oreo vs. Statin," by researcher-educator Nick Norwitz, PhD. What started as a personal journey with metabolic health turned into a captivating exploration of the lipid energy model and lean mass hyper responders. Dr. Norwitz ...

Did you know that nearly 60% of the average American's diet is made up of ultra-processed foods? This staggering statistic highlights a growing public health crisis linked to rising obesity rates and chronic diseases, not only in adults but our children too. In this week’s episode of The Metabolic Link, we dive into a critical conversation with Todd Wagner, a passionate advocate for food safety and health reform. As the founder of FoodFight USA, Todd is dedicated to cleaning up America’s tai...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here. In this journal club episode of The Metabolic Link, we explore the cutting-edge "Metabolic Overdrive Hypothesis" with Dr. Dominic D'Agostino, Dr. Angela Poff, and Victoria Field, diving into the brain’s energy dysregulation in bipolar disorder. The featured paper, "The Metabolic Overdrive Hypothesis: Hyperglycolysis and Glutaminolysis in Bipolar Mania", by authors Dr. Iain Campbell and Dr. Ha...

In our 50th episode of The Metabolic Link podcast, host Dr. Dominic D’Agostino dives deep into the fascinating world of metabolic health through an unexpected lens — bottlenose dolphins. Dr. Stephanie Venn-Watson, a veterinary epidemiologist and public health scientist, joins the show to share her groundbreaking research with the U.S. Navy’s Marine Mammal Program, where dolphins helped reveal the essential role of C15:0. C15:0 is an odd-chain saturated fatty acid that has 3-times more cellu...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.com In this episode of The Metabolic Link, recorded at Metabolic Health Summit 2024, we share Dr. Jeff Volek's full presentation where he takes a deep dive into the "Keto-Adapted Phenotype" with a focus on muscle. Dr. Volek, a leading expert in low-carbohydrate and ketogenic diets, shares groundbreaking research on how ketones impact muscle function and perfo...

Join Dr. Norwitz for a Live Q&A on September 10th at 12pm PT/3pm ET on The Metabolic Initiative platform! Visit this link to register, and also watch his presentation Cookies & Cholesterol Controversy inside the platform (first 7-days are free): https://membership.metabolicinitiative.com/norwitz In this episode, Dr. Nick Norwitz returns to The Metabolic Link podcast to explore the future of personalized medicine and the evolution of metabolic health research with host, Dr. Dominic D’...

Become a member of The Metabolic Initiative to access a robust bank of cutting edge metabolic health content, private ad-free podcast episodes, and earn CMEs here! More than a billion people around the world suffer from mental and neurological disorders, and the numbers are escalating rapidly. Current treatments often fail to provide relief, resulting in many patients struggling with persistent symptoms and resistance to available therapies. In this episode, we’re sharing a full presentation...

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here! In this enlightening episode of The Metabolic Link, Dr. Dominic D'Agostino sits down with Dr. Mary Newport to delve into the world of Alzheimer's disease, discussing her pioneering work with ketogenic metabolic therapy. Dr. Newport shares her personal and inspiring journey with her husband, Steve, whose battle with early-onset Alzheimer's led her to discover the life-changing effects of MCT a...

Become a member of The Metabolic Initiative for ad-free episodes and CMEs In this episode of The Metabolic Link, host Victoria Field interviews Dr. Deanna Kelly, a distinguished professor of psychiatry at the University of Maryland School of Medicine. Dr. Kelly is pioneering nutritional interventions to treat serious mental illness and led a groundbreaking trial on the ketogenic diet for schizophrenia, the only inpatient study of its kind in the U.S. Unfortunately, this privately funded trial...

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs: https://membership.metabolicinitiative.com In this episode of the Metabolic Link Podcast, host Dr. Dom D'Agostino sits down with Dr. Robert Lustig to discuss groundbreaking research unifying different models of obesity. They dive deep into the flaws of the traditional energy balance and carbohydrate-insulin models and introduce a compelling integrative theory encompassing the impact of obesogens, redox bio...

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs: https://membership.metabolicinitiative.com In this interview, host Victoria Field sits down with Dr. Casey Means, a Stanford-trained physician, entrepreneur, and New York Times bestselling author of the new book Good Energy. Dr. Means shares her inspiring journey from being a head and neck surgeon to leaving traditional medicine and becoming a leading voice in the metabolic health field. They take a deep d...

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs! Registered dietitian, Lily Nichols, RDN, CDE, is back on The Metabolic Link, this time in an intimate interview that dives into the critical links between metabolic health, perinatal nutrition, and long-term wellbeing. This episode dives deep into how nutrition during the childbearing years can affect not only mothers but their children throughout their lives. Lily, who is also a New York Times bestsellin...

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs! Join us in this enlightening episode as we dive deep into the emerging research behind Urolithin A and its impact on mitochondrial health with Dr. Anurag Singh, a leading expert in the field and the Chief Medical Officer of Timeline. The discussion spans various facets of Urolithin A, from its origin in pomegranates and other foods to its potential in improving mitochondrial health, muscle strength, and ...

Become a member of The Metabolic Initiative for exclusive episodes and earn CMEs! Dive into the core of nutrition science with Dr. Dominic D'Agostino and Dr. Nina Teicholz, and uncover the remarkable benefits of saturated fats, unravel the complexities of LDL cholesterol, and dig into the heated debate surrounding food addiction and ethical meat consumption. Dr. Teicholz sheds light on the misunderstood facets of dietary fats, debunking prevalent myths about cholesterol, highlighting po...

Become a member of The Metabolic Initiative for exclusive episodes and to earn CMEs In this episode, recorded at Metabolic Health Summit 2024, Dr. Richard Johnson dives into the groundbreaking research that has uncovered the central role of fructose in driving the epidemics of obesity, diabetes, and a wide range of other metabolic diseases. Dr. Johnson presents compelling evidence that fructose, a seemingly innocuous sugar, is in fact a key trigger for activating a powerful biological survi...

In this episode of The Metabolic Link, Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff dive into a fascinating new paper that compares the metabolic and immune impacts of ketogenic and vegan diets in humans. The study, titled “Differential Peripheral Immune Signatures Elicited by Vegan Versus Ketogenic Diets in Humans” takes a deep dive into the multi-omic effects of these two very different dietary approaches. The researchers found that just two weeks on a ketogenic diet signific...

The following Metabolic Link episode was originally filmed at Metabolic Health Summit 2024 and we're excited to share it with you today in its entirety! In this presentation, Dr. Andy Galpin, a human performance scientist, shares his insights on utilizing scientific principles, specifically the 'Biomolecular Athlete' concept, to achieve athletic excellence. He emphasizes the importance of individualized strategies that consider sleep, diet, stress, respiratory rates, and blood chemistry. The ...

This week’s episode of The Metabolic Link features an illuminating sit-down interview with Dr. Jeff Volek, a professor at The Ohio State University. With a PhD in Kinesiology specializing in exercise and nutrition science from Penn State University, Dr. Volek has performed cutting edge research on how humans adapt to diets restricted in carbohydrates with a dual focus on clinical and performance applications of nutritional ketosis. His scholarly work includes more than 300 peer-reviewed scien...

This week's episode of The Metabolic Link features a full presentation from Metabolic Health Summit 2024. Dr. Ben Bikman, professor at Brigham Young University, dives deep into the intricacies of fat and its relationship to metabolic health. This is the full presentation he delivered at Metabolic Health Summit 2024 in Clearwater Beach, Florida. In it he shares his expertise on the link between body fat, insulin resistance, and chronic diseases such as obesity and diabetes. Throughout this tal...

This week’s episode of The Metabolic Link features an illuminating sit-down interview with Dr. Georgia Ede, a Harvard-trained psychiatrist specializing in nutrition science and brain metabolism. With over 25 years of clinical experience, including 12 years as a college psychiatrist and nutrition consultant at Smith College and Harvard University Health Services, Dr. Ede was the first to offer students nutrition-based approaches as an alternative to psychiatric medications. She speaks internat...

In this episode of The Metabolic Link, Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field recap Metabolic Health Summit 2024, the world’s leading medical and scientific conference on metabolic health. Listen to this episode to get an inside look at the top scientific highlights and surprising moments from the perspective of the hosts who made it happen. Want to learn about all the cutting-edge research and scientific insights on metabolic health and therapy that you won’t find anywh...

We’ve just launched an extra and exciting episode of The Metabolic Link podcast! It features an eye-opening conversation between our host Dominic D’Agostino PhD, and guests Dave Feldman and Dr. Nick Norwitz, two researchers and MHS 2024 speakers spearheading investigations into the lean mass hyperresponder (LMHR) phenotype. Dave Feldman is a software engineer who became deeply interested in lipidology after seeing his cholesterol spike on a low-carb, high-fat diet. He has since performed self...

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dr. Dominic D’Agostino and Dr. Jonathan Jun, a pulmonary critical care and sleep medicine physician at Johns Hopkins. He is an expert in the diagnosis and treatment of sleep-disordered breathing, and in the care of critically ill patients in the Medical ICU. He is a member of the Sleep Fellowship Program Evaluation and Clinical Competency Committee and provides teaching to medical students and re...

In this episode, our co-hosts Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field discuss two recent scientific papers on the metabolic effects of allulose and how blocking fructose intake may help fight cancer. The first paper examines how allulose consumption influences metabolic factors like appetite, blood sugar, and insulin sensitivity through the release of key gut hormones and effects on carbohydrate digestion and metabolism. The second paper reviews multiple lines of evidence ...

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dr. Dom D’Agostino and Chad Vanags, a successful entrepreneur who is navigating a stage 4 cancer diagnosis with courage and purpose. After being diagnosed with stage 4 lung cancer in 2022 at just 39 years old, Chad has been documenting his journey to becoming “metabolically, physically, and mentally elite” to continue pursuing his life's vision. In this wide-ranging discussion, we cover: 💪 Chad...

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dominic D'Agostino, PhD, and Franziska Spritzler, RD, CDE. Franziska is a registered dietitian and certified diabetes educator who specializes in low-carb and ketogenic diets. She has been following a low-carb approach for over a decade. In this episode, we cover: 💡 The essential tools Franziska uses when helping clients adhere to low-carb diets 💡 Managing and interpreting changes in blood work on...

In this episode, our co-hosts Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff discuss two recent scientific papers on the potential metabolic connections to psychiatric disorders and mindfulness-based interventions. The first paper is a systematic review on the efficacy of low-carb and ketogenic diets for treating mood and anxiety disorders. They discuss the importance in defining what constitutes a low-carb or ketogenic diet in research studies. Our hosts also discuss the limited...

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dr. Dominic D'Agostino and Dr. Kyle Gillett, a board-certified physician in family and obesity medicine who provides holistic care to his patients. He earned his medical degree at the University of Kansas School of Medicine, practices at the Gillett Health Clinic in Olathe, Kansas, and is the host of The Gillett Health Podcast. His practice focuses on preventive, integrative, and precision medicin...

This week's episode of The Metabolic Link features an eye-opening discussion between Metabolic Health Summit organizer Victoria Field and prenatal nutrition expert Lily Nichols, RDN, CDE. Lily is the author of two bestselling books - Real Food for Pregnancy and Real Food for Gestational Diabetes. Her work focuses on evidence-based, critical analysis of conventional pregnancy nutrition recommendations. In this episode, we cover: Evaluating macronutrient needs in pregnancy, including research s...

In this week’s episode of The Metabolic Link, double board certified psychiatrist and obesity medicine physician, Dr. Shebani Sethi, takes us on a deep dive into the emerging field of metabolic psychiatry. Dr. Shebani Sethi is a psychiatrist and obesity medicine physician at Stanford University School of Medicine. She is the founding director of the Stanford Metabolic Psychiatry Clinic, where she researches dietary and pharmacological interventions to improve metabolic health and mental illne...

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dominic D’Agostino, PhD, and Dr. Abbi Hernandez, an assistant professor at the University of Alabama at Birmingham. Dr. Hernandez received her PhD from the University of Florida, where she studied age and diet related changes in neurological function and cognitive health. Her research has focused on investigating the potential of ketogenic diets and time-restricted feeding for preventing age-relat...

In this week’s episode, host Victoria Field speaks with Matt Baszucki and Dr. Iain Campbell about their lived experiences with bipolar disorder and the therapeutic effects of the ketogenic diet, potential root causes of the mental illness, and their mission to spread awareness and education around ketogenic dietary therapy as a treatment for bipolar disorder. Iain Campbell, PhD, is the Baszucki Research Fellow in Metabolic Psychiatry at the University of Edinburgh. He has a PhD in Global Heal...

In this episode, our co-hosts Victoria Field, Dominic D’Agostino, PhD, and Angela Poff, PhD, discuss two recent scientific studies that focus on the potential metabolic connections to neurodegenerative diseases. Study 1: Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease The study delves into the molecular changes causing a neuron's transition from healthy to degenerative, as seen in sporadic Alzheimer's, which is the most prevalent form of A...

This week’s episode of The Metabolic Link features an in-depth conversation between our host Dominic D’Agostino, PhD, and Jeff Volek, PhD, RD, on a wide range of topics as well as questions submitted by our Twitter followers! Dr. Volek is a registered dietitian and professor in the Department of Human Sciences at The Ohio State University. For the last 25 years, he has performed translational research on how humans adapt to ketogenic diets with a dual focus on clinical and performance applica...

On this week’s episode of The Metabolic Link, our host and MHS Co-organizer Victoria Field interviewed Kelly Faltersack, a registered dietitian nutritionist, who specializes in treating patients with ketogenic diet therapy as an effective treatment for epilepsy and other neurological disorders. Kelly Faltersack MS, RDN, LDN, CD is a registered dietitian nutritionist at UW Health in Madison, Wisconsin. Kelly has over 10 years of experience as a registered dietitian nutritionist, and five years...

This week’s episode of The Metabolic Link features an enlightening conversation between our host Dr. Dominic D’Agostino and Dr. Satchin Panda, PhD on the fascinating connection between time-restricted eating, circadian rhythm, and metabolic health. A leading expert in the field of circadian rhythm research, Dr. Panda is a professor at the Salk Institute for Biological Studies and a founding executive member of the Center for Circadian Biology at the University of California. Have you been he...

This week’s episode of The Metabolic Link features an interview with Nicole Laurent, a Licensed Mental Health Counselor who helps her clients use ketogenic dietary therapy as a treatment for mental illness and neurological issues. Nicole was one of seven pioneers of Metabolic Psychiatry recognized by the Baszucki Brain Research Fund and the Milken Institute with the Metabolic Mind Award in 2022. What is Metabolic Psychiatry? Metabolic psychiatry is an emerging field that focuses on targeting ...

In this Journal Club episode, The Metabolic Link Hosts Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field review recent research uncovering the potential impact of high blood glucose on stroke outcomes and the positive influence of exercise on Alzheimer’s disease. An ischemic stroke happens when a blood vessel in the brain is occluded. This prevents oxygen and nutrients from reaching a region of the brain, ultimately causing some of that tissue to die. A hemorrhagic stroke occurs wh...

It’s said that more than one billion individuals around the world suffer from migraines each year. A migraine isn’t your average headache. It’s often completely debilitating and may include sensitivity to light and sound, vomiting, severe pain, and other symptoms that can wreak havoc on quality of life. Despite being one of the most common neurological disorders on the planet with a high prevalence in (particularly female) young adults, many of those troubled by migraines do not receive effec...

On this episode of The Metabolic Link, we’re sitting down with Dr. Kwadwo Kyeremanteng to discuss his experience as a critical care physician during 2020, the importance of metabolic health in fighting viral infections, and how improving global metabolic health will make us more resilient against future illnesses. Dr. Kyeremanteng is an ICU doctor and intensivist at The Ottawa Hospital who seeks to increase the efficiency of medical care with cost-effectiveness, dignity, and justice in mind ...

You won’t be surprised to hear that a night of poor sleep can affect how good you feel the next day. But did you know that disruptions in sleep quality, especially when they occur chronically, can have a major negative impact on your cognitive function, mood, and overall metabolic health? On this week’s Journal Club episode of The Metabolic Link, co-hosts Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field dive into two research publications exploring how meal timing in shift workers ...

On this week’s episode of The Metabolic Link, host Dr. Dominic D’Agostino is sitting down with neuroscientist, Tommy Wood, MD, PhD, to discuss optimizing human health and cognitive function. In this interview, Dom explores a wide variety of fascinating topics with Dr. Wood. They uncover why cognitive demand may be important in preventing devastating neurological disorders like dementia, the importance of monitoring cardiovascular risk biomarkers including insulin, ApoB, homocysteine, an...

On this week’s episode of The Metabolic Link, we’re sitting down with OBGYN and Ketogenic Metabolic Therapy Expert, Jaime Seeman, MD, to discuss the importance of metabolic health through a woman's life stages. In this interview, we explore how and why a woman might want to optimize their metabolic health in their fertile years, into menopause, and beyond. We also uncover the specific issues women can face along the way, the potential of metabolic therapy in improving hormone func...

On this week’s Journal Club episode of The Metabolic Link, co-hosts Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field discuss two seemingly conflicting research studies exploring the effects of ketosis on muscle health in models of atrophy. Atrophy refers to the wasting of a body tissue or organ that occurs due to the degeneration of cells. Atrophy of vital tissues such as the skeletal muscle occurs in numerous pathological catabolic conditions, such as in cancer cachexia, motor neu...

On this week’s episode of The Metabolic Link, Dr. Dominic D’Agostino is sitting down with world-renowned metabolic scientist, Ben Bikman, PhD, to explore the ins and outs of insulin resistance, Type 2 Diabetes Mellitus (T2DM), and ways to manage, and even reverse, both. In this discussion, Dr. Bikman makes a case for why testing fasting insulin should be a part of the diagnostic and treatment equation when addressing T2DM, the difference between pathological and physiological insulin resista...

In this Journal Club episode, The Metabolic Link Hosts Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field review recent research exploring the use of ketogenic metabolic therapy in Parkinson’s Disease and Mental Illness. The first study discussed investigates the effects of a ketogenic diet applied prior to versus after the onset of Parkinson’s disease in an animal model. Parkinson’s disease is a highly prevalent disease, with over 6 million people worldwide who suffer from it. We un...