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Metabolic Mind

Metabolic Mind

Bret Scher, MD FACC

Metabolic Mind is working to transform the study & treatment of mental disorders by exploring the connection between metabolism & brain health. Metabolic interventions like ketogenic therapy are being used to treat serious mental illnesses like Bipolar Disorder, Schizophrenia, & Major Depressive Disorder. We explore topics that can help you understand how Metabolic Psychiatry might help you or a loved one treat mental disorders Watch our videos at https://www.youtube.com/@metabolicmind Our channel is for information only. Consult your physician before changing your lifestyle or medications.

48 - What is a Good Bipolar Diet?
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  • 48 - What is a Good Bipolar Diet?

    When looking for information about how nutrition can improve brain health, it is important to remember that you cannot necessarily believe everything you read. Dr. Bret Scher discusses a recent article from Healthline called Foods to Eat and Avoid With Bipolar Disorder as one example of an article that makes unsubstantiated claims. The article cites flawed studies and also jumps to conclusions that are not science-based. Will eating more beans, chocolate and whole grains help your bipolar disorder? Not likely. When looking at articles that suggest nutritional interventions for mental illness, it is important to realize that ketogenic therapy is a unique dietary strategy that shifts the metabolic state of our bodies and brains. Ketogenic therapy is not a particular diet, but a physiologic state. By reducing carbs, we can shift to a ketone based metabolism, and this process has strong neurological and biological effects. It is important to distinguish ketogenic therapy, which has a growing evidence-base, from generalized and unsupported nutritional advice that is prevalent on the internet. Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources: https://www.metabolicmind.org/families-and-peers Read about the completed and ongoing research exploring ketogenic therapy for psychiatric conditions: https://www.metabolicmind.org/research Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ Article discussed: https://www.healthline.com/health/bipolar-disorder/foods-for-mania-and-depression On the related topic of misinformation about nutrition for brain health see “New book: Change Your Diet, Change Your Mind by Metabolic Psychiatry Pioneer Dr. Georgia Ede” https://www.youtube.com/watch?v=ws_AlyJNo2I Read Change Your Diet, Change Your Mind: https://www.amazon.com/Change-Your-Diet-Mind-Powerful/dp/1538739070 About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #MetabolicNeuroscience#NutritionalKetosis#MentalIllness#AlternativeTreatment#KetoForDepression#KetoForBipolar#MedicalKeto#KetogenicTherapy#BipolarDiet

    Mon, 13 May 2024 - 07min
  • 47 - Can a Medical Keto Diet Treat Depression in College Students? - with Dr. Jeff Volek

    Can ketogenic therapy help college students living with depression? Jeff Volek, PhD, RD, is investigating this question in a pilot study at The Ohio State University, where he is a professor in the Department of Human Sciences. Dr. Volek has been a world-renowned expert in ketogenic diets for more than two decades. He has pioneered critical work raising awareness of how the keto diet can reverse diabetes and metabolic syndrome and enhance athletic performance and recovery. In this interview with Dr. Bret Scher, Dr. Volek discusses his new work exploring ketogenic therapy for depression, including some of the challenges, especially for a college-age population, as well as the immense benefits. The study results so far are extremely promising, with students who maintain ketosis reporting a dramatic improvement in symptoms. Other topics they cover include how metabolic dysfunction underlies most chronic diseases, what a well-formulated keto diet looks like, and the importance of bringing ketogenic therapy into academic programs in dietetics and medicine. Dr. Volek shares that he is unaware of any academic programs that instruct on keto nutrition as a powerful medical intervention–this is a critical step to make metabolic therapies more mainstream. Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Experts in this episode: Jeff Volek, PhD, RD https://u.osu.edu/caffre/people/volek/ https://www.amazon.com/stores/Jeff-Volek/author/B001JOYRQE?ref=ap_rdr&isDramIntegrated=true&shoppingPortalEnabled=true Clinical trial mentioned in the video: https://www.clinicaltrials.gov/study/NCT06080932?cond=depression&term=Ketogenic%20Diet&rank=2&limit=10 If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources: https://www.metabolicmind.org/families-and-peers Read about the completed and ongoing research exploring ketogenic therapy for psychiatric conditions: https://www.metabolicmind.org/research Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #MetabolicNeuroscience#NutritionalKetosis#MentalIllness#AlternativeTreatment#KetoForDepression#KetoForBipolar#MedicalKeto#KetogenicTherapy#DepressionDiet#Depression

    Mon, 06 May 2024 - 29min
  • 46 - Does the Brain Need Carbs?

    The emerging field of metabolic psychiatry is demonstrating that many patients may be able to effectively treat serious psychiatric conditions, like bipolar disorder, major depression and schizophrenia, with ketogenic therapy. However, some individuals object to a medical keto diet claiming that the brain needs carbs. Ketogenic diets usually do, in fact, include some dietary carbs, but even if they didn’t, this is a false assertion. Some clinicians and the American Diabetes Association may make this false declaration because they are confusing carbs with glucose. The brain does require glucose (synonymous with blood sugar). While glucose can come from dietary carbs, it can also be produced from fat and protein through a process called gluconeogenesis. In this video, Dr. Bret Scher dives into the details, as well as explaining why research related to dietary interventions can be misinterpreted, and can even become a source of confusing misinformation when taken out of context. Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #Depression#MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#MentalIllness#AlternativeTreatment#KetoForDepression#KetoForBipolar#MedicalKeto#KetogenicTherapy

    Mon, 29 Apr 2024 - 04min
  • 45 - Solutions to Prevent Early Death in Bipolar Disorder with Dr. Melvin McInnis

    People with bipolar disorder are four to six times more likely to die prematurely compared to those without a psychiatric disorder. (In comparison, smokers are two to three times more likely to have a shortened lifespan.) There are several contributing factors, including things like metabolic dysfunction, as well consequences of lifestyle choices influenced by disease burden Science needs to urgently investigate these extremely poor outcomes in search of more effective interventions that will enhance quality of life for people with bipolar disorder. Emerging evidence and clinical experience indicate that ketogenic and metabolic therapies may have a central role in addressing this concerning trend. Dr. Bret Scher interviews Dr. Melvin McInnis, Professor of Bipolar Disorder and Depression at University of Michigan, on these pressing topics. Dr. McInnis is working on a pilot trial that will look at a “ketogenic mimicking diet,” augmenting a low carb diet with exogenous ketones in bipolar disorder. Could this address unwanted metabolic dysfunction in this population? We applaud Dr. McInnins and his team for asking the question. Experts in this episode: Melvin McInnis, M.D., FRCPsych https://medicine.umich.edu/dept/psychiatry/melvin-mcinnis-md https://medicine.umich.edu/dept/prechter-program/melvin-g-mcinnis-md-frcpsych Study The Heinz C. Prechter Longitudinal Study of Bipolar Disorder https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837550/ If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources: https://www.metabolicmind.org/families-and-peers Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#MentalIllness#AlternativeTreatment#MedicalKeto#KetogenicTherapy #KetoForBipolar#Bipolar

    Mon, 22 Apr 2024 - 41min
  • 44 - Trailblazing Stanford Trial Shows Keto Improves Serious Mental Illness - with Dr. Shebani Sethi

    A pioneering, peer-reviewed pilot trial at Stanford, supported by funding from by Baszucki Group and others, investigated a 4-month keto diet intervention for individuals diagnosed with bipolar disorder or schizophrenia who also had metabolic abnormalities such as insulin resistance or impaired glucose tolerance. They saw dramatic psychiatric and metabolic improvements that warrant further research investigations and offer hope to patients looking for new treatment options. Dr. Bret Scher interviews Shebani Sethi, MD, ABOM of Stanford University School of Medicine and Founding Director of the Stanford Metabolic Psychiatry Clinic. She discusses the details of this study which represents a milestone in the field of metabolic psychiatry: It is the first to investigate ketogenic therapy in serious mental illness since 1965. Standard of care treatments for bipolar disorder and schizophrenia typically exacerbate metabolic dysfunction, often leading to increased cardiometabolic risk and comorbidities that shorten lifespan. This trial showed unique outcomes in terms of dual improvements in both metabolic function and psychiatric symptoms Key findings of the single-arm pilot trial include: - 79% of participants showed clinically meaningful psychiatric improvement - 100% of participants who met the criteria for metabolic syndrome were in remission by the end of the study. - Reductions were seen in weight, body mass index (BMI), waist circumference, and visceral adipose tissue. - Improvements were identified across all psychiatric measures. & more Based on the results of Dr. Sethi’s study, along with preliminary data from a University of Edinburgh trial, Baszucki Group has followed its pilot trial grants with the establishment of a new global funding program: ReThink Bipolar: Researching Therapeutic Integration of Nutritional Ketosis in Bipolar Disorder. To date, the program has announced $8M in funding to McLean Hospital and the University of Pittsburgh for randomized controlled trials combining mechanistic explorations with a clinical ketogenic intervention. Experts in this episode: Shebani Sethi MD, ABOM https://med.stanford.edu/profiles/shebani-sethi#bio Twitter: @ShebaniMD Study: https://www.sciencedirect.com/science/article/pii/S0165178124001513?via%3Dihub Stanford news release: https://med.stanford.edu/news/all-news/2024/04/keto-diet-mental-illness.html If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources: https://www.metabolicmind.org/families-and-peers Dive into the research happening on metabolic psychiatry: https://www.metabolicmind.org/research Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#MentalIllness#AlternativeTreatment#MedicalKeto#KetogenicTherapy #KetoForBipolar#KetoForSchizophrenia

    Mon, 15 Apr 2024 - 22min
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