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The Dr. Gabrielle Lyon Show
The Dr. Gabrielle Lyon Show promotes a healthy world, and in order to have a healthy world, we must have transparent conversations. This show is dedicated to such conversations as the listener; your education, understanding, strength, and health are the primary focus. The goal of this show is to provide you with a framework for navigating the health and wellness space and, most importantly, being the champion of your own life. Guests include highly trustworthy professionals that bring both the art and science of wellness aspects that are both physical and mental. Dr. Gabrielle Lyon is a Washington University fellowship-trained physician who serves the innovators, mavericks, and leaders in their fields, as well as working closely with the Special Operations Military. She is the founder of the Institute of Muscle-Centric Medicine® and serves patients worldwide.
- 255 - Plant-Based Diets and Muscle: What Two New Trials Found in Older Adults
Eating more plants is not always helpful if it affects muscle health.
Two recent randomized controlled trials published in the American Journal of Clinical Nutrition investigated the effects of replacing animal protein with plant protein in older adults.
One study reported that participants adhering to a vegan diet experienced significant muscle loss over a 12-week period. The other study found that older people on a predominantly plant-based vegetarian diet and doing resistance training gained both muscle and strength over the same 12-week period.
This review looks at the design and results of the studies, considers the importance of both the amount and quality of protein for older adults and provides practical advice on how to put together a plant-based diet to support muscle. Older adults can certainly gain muscle on a predominantly plant-based diet but it's important to be very mindful of certain factors to get the best results.
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonFacebook: https://facebook.com/doctorgabriellelyonYouTube: https://youtube.com/@DrGabrielleLyonX (Twitter): https://x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageChapters:
00:00 - Eating more plants is not automatically healthy for muscle
00:44 - Two new trials on plant protein and muscle in older adults
02:51 - Why protein matters more as we age: anabolic resistance
04:50 - Trial 1: a self-selected vegan diet in adults over 65
06:15 - What happened to muscle in the vegan group
07:18 - Resistance training reduced the losses but did not prevent them
08:36 - Trial 2: the IMPACT trial, vegetarian vs omnivorous diet with lifting
09:41 - Results: both groups gained muscle, omnivores gained more
11:47 - Essential amino acids, protein quality and DIAAS
13:40 - Why protein quality matters less when total protein is high
15:05 - The 2023 mycoprotein study
16:23 - Why a plant-based diet takes more planning
18:03 - Setting your protein requirement: 1.6 grams per kilogram
19:03 - Protein quality on a plant-based diet
20:05 - The takeaway: plant-based eating takes planning
21:50 - Why plant-based is easier to do well today
22:57 - Final thoughts
If you found this episode valuable, share it with someone who would benefit from it.
Studies mentioned in the podcast:
https://pubmed.ncbi.nlm.nih.gov/42680254/https://pubmed.ncbi.nlm.nih.gov/42772454/https://pubmed.ncbi.nlm.nih.gov/33599941/https://pubmed.ncbi.nlm.nih.gov/36822394/https://pubmed.ncbi.nlm.nih.gov/28698222/The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 12 Nov 2026 - 23min - 254 - Dismissed as Hemorrhoids, Diagnosed as Stage 3 or 4 Colon Cancer | NBC's Chloe Melas
NBC News correspondent Chloe Melas joins me to share her experience living with ulcerative colitis for 15 years, a journey she kept private until releasing her new book, The Girl's Guide to Guts, co-written with Judy Batalion. We talk about the differences between IBD and IBS, what blood in the stool might mean, and why one study found that women waited more than twice as long as men to get a diagnosis. Chloe explains her flare plan, how she manages fiber with apples and psyllium, and what it was like to go over ten years without a normal bowel movement. We also discuss colon cancer in adults under 50, celiac disease, diverticulitis, colonoscopy prep, and traveling when your gut is unpredictable. I also explain how essential amino acids help feed the cells that produce the gut's protective mucus. If you’re dealing with bloating, urgency, or bleeding, this conversation can help you recognize when it’s time to call a GI doctor.
Thank you to our sponsors:
Cozy Earth: 20% off home and sleepwear athttps://cozyearth.com with code DRLYONLadder: free 7-day trial, no credit card, plus $10 off your first month athttps://ladder.fit/drlyonBranch Basics: 15% off site-wide athttps://branchbasics.com with code DRLYONConnect with Chloe Melas:
The Girl's Guide to Guts: https://a.co/d/0byBk4InInstagram: https://www.instagram.com/chloemelas/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonFacebook: https://facebook.com/doctorgabriellelyonYouTube: https://youtube.com/@DrGabrielleLyonX (Twitter): https://x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageChapters:
00:47 - Meet Chloe Melas and The Girl's Guide to Guts
03:36 - IBD vs IBS: ulcerative colitis, Crohn's and how they differ
05:30 - Blood, tenesmus and a decade of laxatives
07:30 - What a normal stool looks like
08:31 - Colon cancer in adults under 50
10:00 - Why Chloe decided to share her story
13:04 - IBS symptoms, elimination diets and when to see a GI
16:37 - Colonoscopies, medication and finding the right doctor
19:18 - Shame, silence and women's health
20:52 - Why women wait longer for a diagnosis
22:00 - Chloe's flare plan: sleep, protein and less alcohol
23:40 - Fiber: how much you need and the apple math
28:53 - Psyllium, inulin, guar gum and other fibers
33:13 - What may trigger IBD: antibiotics, environment and genetics
35:58 - Menstrual cycles and other causes behind IBS-like symptoms
37:39 - Celiac disease and why you cannot self-diagnose
41:19 - Celiac in children and early screening
43:28 - Diverticulitis
44:22 - Gut habits to start in your 20s
45:38 - Essential amino acids, threonine and mucin
46:37 - Sleep, hydration and at-home stool tests
49:09 - Raising kids with strong guts
53:17 - Colonoscopy prep that works
55:09 - The white pants story
58:33 - Travel strategies for a sensitive gut
1:00:58 - Judy Batalion and the J pouch
1:03:00 - How ulcerative colitis was once called psychosomatic
If you found this episode valuable, share it with someone who would benefit from it.
Studies mentioned in the podcast:
https://pubmed.ncbi.nlm.nih.gov/36719111/https://pubmed.ncbi.nlm.nih.gov/41569583/Disclaimers:This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 10 Nov 2026 - 1h 04min - 253 - Does Retatrutide Cause Muscle Loss? The TRIUMPH-1 Phase 3 Results Explained
Have you heard about retatrutide?
It's the weight loss drug everybody is talking about. People are buying it online as a research chemical, and patients ask me if I'm prescribing it (I'm not).
A study in the New England Journal of Medicine shared insights into the drug, which is currently not FDA-approved. At the highest dose, people lost an average of 25% of their body weight over 80 weeks, compared with about 4% body weight for those on placebo. The area I care about most—muscle—doesn’t get much attention.
In this episode, I go through the TRIUMPH-1 results, how retatrutide compares with semaglutide and tirzepatide, and what protein and resistance training do for muscle during weight loss.
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: https://www.tiktok.com/@drgabriellelyon
- Facebook: https://facebook.com/doctorgabriellelyon
- YouTube: https://youtube.com/@DrGabrielleLyon
- X (Twitter): https://x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
00:00 Cold open: weight loss we have never seen before with a drug
00:45 TRIUMPH-1 and phase three: a trial of retatrutide in people without diabetes
02:49 Approval and mechanism: phase three is not FDA approval, and retatrutide hits GLP-1, GIP and glucagon
04:53 The headline: 25% of body weight, about 62 pounds, against 15% for semaglutide and 21% for tirzepatide
06:52 Trial design: 2,339 adults, 80 weeks and no prescribed diet
08:45 Results by dose: 17 to 28% on retatrutide, about 4% on placebo and the bariatric surgery comparison
10:29 The top dose: more than half dropped below a BMI of 30, plus the 104-week extension
13:10 Beyond the scale: waist, blood pressure, triglycerides, insulin, CRP, knee pain and sleep apnea
15:37 The muscle question: TRIUMPH-1 does not report body composition
16:32 Phase 2 DEXA data: about 30 to 40% of weight lost was lean tissue
18:22 Protein and training: the 1.2 versus 2.4 g/kg deficit study
20:24 The goal: lose fat and keep muscle
21:29 Pharmacology: SURMOUNT-5 put tirzepatide at 20% against 14% for semaglutide
22:30 What glucagon adds, and why there is no head-to-head trial yet
25:23 Side effects, and why more drug is not better medicine
27:23 What TRIUMPH-1 changes, and the study still missing
28:48 Not FDA approved, and where obesity pharmacology goes next
29:51 Close: the goal was never weight loss
Study and References:
Jastreboff AM, Kaplan LM, Davies MJ et al. 2026. Retatrutide, a triple hormone receptor agonist, for treatment of obesity. N Engl J Med. DOI: https://doi.org/10.1056/NEJMoa2604169
Coskun T et al. 2025. Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial. PMID: 40609566 https://pubmed.ncbi.nlm.nih.gov/40609566/
Longland TM et al. 2016. Higher compared with lower dietary protein during an energy deficit combined with intense exercise promotes greater lean mass gain and fat mass loss: a randomized trial. PMID: 26817506 https://pubmed.ncbi.nlm.nih.gov/26817506/
Aronne LJ et al. 2025. Tirzepatide as compared with semaglutide for the treatment of obesity. PMID: 40353578 https://pubmed.ncbi.nlm.nih.gov/40353578/
Wilding JPH et al. 2021. Once-weekly semaglutide in adults with overweight or obesity. PMID: 33567185 https://pubmed.ncbi.nlm.nih.gov/33567185/
Jastreboff AM et al. 2022. Tirzepatide once weekly for the treatment of obesity. PMID: 35658024 https://pubmed.ncbi.nlm.nih.gov/35658024/
Disclaimer:The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 05 Nov 2026 - 30min - 252 - Muscle Physiologist: It Took Two Soy Burgers to Approach the Muscle Response of One Beef Patty | Dr. David Church
How do the amino acids in a soy patty and a beef patty compare once they reach your blood?
In a trial he helped design, Dr. David Church matched a 4-ounce beef patty against a soy-based burger. He had to double the soy to roughly match the single beef patty in essential amino acids. The blood amino acid levels shocked him.
David joins me at Protein Summit 3.0 to explain what happened.
He also tells me why muscle protein breakdown is so much harder to measure than synthesis, and shares insights from his 21-day testosterone study, where the men on testosterone lost all of their weight as fat while the placebo group lost about half of theirs as fat-free mass.
Thank you to our sponsors:
- Cozy Earth: 20% off home and sleepwear at cozyearth.com with code DRLYON
- Timeline: an additional 20% off at timeline.com/lyon
- Bon Charge: 30% off sitewide in their Black Friday sale with code DRLYON30
Find Dr. David Church at:
- UAMS profile: https://uams-triprofiles.uams.edu/profiles/profile/5838748
- Instagram: https://www.instagram.com/dr.myohead
- LinkedIn: https://www.linkedin.com/in/david-church-6b0662280
- X (Twitter): https://x.com/DrMyohead
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: https://www.tiktok.com/@drgabriellelyon
- Facebook: https://facebook.com/doctorgabriellelyon
- YouTube: https://youtube.com/@DrGabrielleLyon
- X (Twitter): https://x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
0:00 – Dr. David Church on the Nandrolone Aging Study in Mice
3:17 – What Testosterone Changed in Men During a 21-Day Energy Deficit
6:14 – Androgens, Hormones and What We Still Do Not Know in Women
9:43 – Stable Isotope Tracers Explained With Legos
10:56 – Why Muscle Protein Breakdown Is So Hard to Measure
13:23 – How Testosterone May Recycle Amino Acids Inside the Muscle Cell
16:01 – Net Protein Balance, Burns and Whole-Body Protein
18:38 – Obesity, Anabolic Resistance and the 1.2 g/kg Protein Target
24:38 – Testosterone and Protein as Complementary Levers
26:15 – Nandrolone, Satellite Cells and Muscle Memory
32:50 – The Soy Burger vs. Beef Patty Trial
40:18 – Plant Protein, Low Appetite and Essential Amino Acid Supplements
41:16 – GLP-1 Responders and Why Dr. Lyon Uses Essential Amino Acids
47:49 – Are Essential Amino Acids Requirements Higher Than We Thought?
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 03 Nov 2026 - 58min - 251 - Essential Amino Acids Explained: Protein Quality, Leucine, BCAAs and How Much You Need
Protein has become a numbers game, and the numbers leave out the essential amino acids your muscle, brain and metabolism depend on. Protein is how you get them, and its quality may change how well you age.
In this episode, Dr. Gabrielle Lyon brings together some of her favorite moments with Dr. Don Layman, Dr. Heather Leidy and Dr. Jess Gwin to break down the essential amino acid requirement, cut through the confusion on protein quality (what a protein label leaves out, plant vs. animal sources, branched-chain amino acids, and leucine), and explain what the research says about essential amino acids in brain function, mood, sleep, energy deficit, and anabolic resistance as we age.
If you have ever wondered what your protein label isn't telling you, or why half an ounce of nuts and an ounce of lean beef count as the same serving, this conversation offers a clear, practical look at what the science says.
Thank you to our sponsors:
- BodyHealth: 20% off your first order at bodyhealth.com with code LYON20
- Tushy: 10% off your first bidet order at hellotushy.com with code DRLYON
Find Dr. Don Layman, Dr. Heather Leidy and Dr. Jess Gwin at:
- Dr. Heather Leidy: https://nutrition.utexas.edu/directory/heather-leidy/
- Dr. Don Layman: https://x.com/donlayman
- Dr. Jess Gwin: https://www.researchgate.net/profile/Jess-Gwin
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: @drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- YouTube: youtube.com/@DrGabrielleLyon
- X (Twitter): x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
0:00 – Why the Requirement Is Essential Amino Acids, From Muscle to Mood and Sleep
3:24 – Dr. Jess Gwin on Protein Quality and Why the Dietary Guidelines Miss It
5:36 – What a Protein Label Does and Doesn't Tell You
6:50 – Nuts vs. Lean Beef and the Cost of Going Plant-Based
9:35 – Dr. Don Layman on Branched-Chain Amino Acids, Leucine and mTOR
11:19 – How Much Protein Reaches the Leucine Threshold
14:00 – Dr. Jess Gwin on Essential Amino Acids Under Energy Deficit and Stress
16:36 – Dosing, Aging and Anabolic Resistance
19:26 – Whole Foods vs. Amino Acid Powders as Tools
21:29 – Dr. Lyon's First-Meal Routine
Disclaimers:This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 29 Oct 2026 - 22min - 250 - Dr. Mike Ormsbee: Eating Before Bed - What Probes in Belly Fat Revealed About Protein Snacks
Eating before bed: harmful or helpful? Dr. Mike Ormsbee breaks down protein before bed, casein vs. whey, fat metabolism, sleep, and resistance training for postmenopausal women.
Late-night eating comes with many rules of thumb, and most people follow them without knowing what the research shows. Dr. Mike Ormsbee, a researcher at Florida State University, has spent years measuring how protein before bed affects metabolic rate, overnight fat burning, sleep, and recovery. If you lift, want to keep muscle as you age, or have been told to stop eating after dinner, his view on casein vs. whey and bedtime snacks may change what you keep in the kitchen.
Thank you to our sponsors:
- BodyHealth: 20% off at https://bodyhealth.com with code LYON20
- One Skin: 15% off with code Doctor Lyon at oneskin.com
- Ladder app: ladder.fit/doctorlion, free 7-day trial, no credit card, $10 off the first month
Find Dr. Mike Ormsbee at:
- Visit www.mikeormsbee.com/lyon
- Instagram: https://www.instagram.com/mikeormsbee/?hl=en
- Course, Changing Body Composition Through Diet and Exercise (The Great Courses): https://shop.thegreatcourses.com/changing-body-composition-through-diet-and-exercise
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: @drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- YouTube: youtube.com/@DrGabrielleLyon
- X (Twitter): x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
0:00 – The Eating-Before-Bed Debate and How Pre-Sleep Feeding Is Defined
5:00 – Metabolic Rate, Belly-Fat Probes and Casein vs. Whey
9:14 – Exercise as Our "Metabolic Apology" for Poor Diet and Poor Sleep
15:07 – Resistance Training and Fat Metabolism
21:58 – Inside the Five-Year NIH Study: Lifting vs. Cardio After Menopause
31:59 – Growth Hormone, Fed vs. Fasted Training and Why Obesity Slows the Response
36:29 – Protecting Muscle During Rapid Weight Loss and How Much Lifting Is Enough
43:09 – What the Postmenopausal Study Is Showing So Far
50:00 – Sleep, Evening Exercise and the Hungry-at-Night Protein Snack
55:47 – Does Excess Protein Turn to Fat? Older Adults, Calories and Timing
1:02:25 – Collagen, Creatine and Ketones: What He Takes and Skips
1:11:15 – Casein vs. Whey, Future Research and His Best Advice for Postmenopausal Women
Disclaimers:This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 27 Oct 2026 - 1h 21min - 249 - How to Raise Strong Kids: Protein, Strength Training and Building Bone Before Adulthood
Childhood and adolescence provide a one-time biological opportunity: our kids' bodies are primed to grow, build tissue, and develop cognitive capacity. But to do that, they need the right raw materials.
In this video, we break down why restricting nutrient-dense foods in growing children puts their development at risk. We explore the critical role of highly bioavailable nutrients like heme iron and vitamin B12, how nutrient status directly impacts academic performance and attention, and why building muscle and metabolic reserve early protects your health decades later.
Don't wait until your children are 40 and struggling with their health to teach them what strong looks like.
Thank you to our sponsor:
Rula: https://www.rula.com/drlyon
Chapters:
00:00 - Introduction: Why We Must Start in Childhood
01:14 - Kids Are Not "Little Adults": Growth vs. Maintenance
02:25 - Puberty & Protein Metabolism: The Role of Leucine
03:50 - How Much Protein Do Kids Actually Need? (RDA vs. Modern Data)
06:10 - Protein Requirements for Active and Athletic Youth
08:35 - Upgrading the Typical Kid Diet: High-Quality Protein Sources
11:47 - Bone Accrual & Debunking the Youth Strength Training Myth
14:10 - Neurological Strength: Why Kids Get Stronger Without Bulking Up
17:15 - Resistance Training for Girls: Hormones, Strength & Busting the "Bulk" Fear
20:50 - Critical Micronutrients for Brain & Body: Iron and B12
22:45 - Building Lifelong Biological Reserve: Raising Capable Humans
Explore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/
Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon
TikTok: https://tiktok.com/@drgabriellelyon
X (Twitter): https://x.com/drgabriellelyon
Facebook: https://www.facebook.com/doctorgabriellelyon
Studies mentioned in the podcast:
https://pubmed.ncbi.nlm.nih.gov/42752819/
https://pubmed.ncbi.nlm.nih.gov/35020179/
https://pubmed.ncbi.nlm.nih.gov/35011099/
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 22 Oct 2026 - 25min - 248 - Dr. Dariush Mozaffarian: How the Food System Got Us Sick. Can We Fix It?
What you choose to eat is the single most important decision you make every day—impacting your metabolic health, your family, the economy, and the future of our food supply.
In this episode, world-renowned cardiologist and nutrition expert Dr. Dariush Mozaffarian breaks down the "Food is Medicine" movement, cuts through dietary confusion (fats vs. carbs, food label marketing, and ultra-processed ingredients), and reveals how public demand, science, and policy can repair a broken food system. If you have ever felt overwhelmed in the grocery aisle or wondered how to separate real nutrition science from industry marketing, this conversation provides a clear, practical roadmap.
Thank you to our sponsors:
BodyHealth: 20% off at https://bodyhealth.com with code LYON20
Timeline: 20% off at http://www.timeline.com/lyon
Wildgrain: $40 off first box + free croissants for life at http://www.wildgrain.com/drlyon40 with code LYON40
Food is Medicine by Dr. Dariush Mozaffarian:https://us.macmillan.com/books/9781250394286/foodismedicine/
Chapters:
00:00 - The Reality of Our Current Food System
05:12 - Carbs vs. Fats: Breaking Down the Science
18:40 - How to Read a Food Label Like an Expert
32:15 - Ultra-Processed Foods & Why Real Food Spoils
48:30 - The History of Food Policy: From the Green Revolution to Today
01:05:10 - The Economics of Chronic Illness
01:21:40 - The Crucible: Science, Government, and Consumer Power
01:31:54 - "Food is Medicine" & Dr. Mozaffarian's Ultimate Message
Explore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patientConnect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyonTikTok: https://tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyon/If you found this episode valuable, share it with someone who would benefit from it. Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 20 Oct 2026 - 1h 33min - 247 - How Much Protein Do You Need? Top Scientists Still Disagree
Protein is in everything right now: coffee, chips, cookies, bars. But despite the massive marketing hype, the world’s leading scientists are still debating fundamental questions about how much protein we actually need and how the body uses it. Fresh off the Protein Summit 3.0 at Texas A&M, Dr. Gabrielle Lyon breaks down what top researchers agreed on, why treating protein as a single number is a major mistake, and how to stop falling for "high-protein" health halos in the grocery store.
Find Dr. Gabrielle Lyon at:
Protein is in everything right now: coffee, chips, cookies, bars. But despite the massive marketing hype, the world’s leading scientists are still debating fundamental questions about how much protein we actually need and how the body uses it. Fresh off the Protein Summit 3.0 at Texas A&M, Dr. Gabrielle Lyon breaks down what top researchers agreed on, why treating protein as a single number is a major mistake, and how to stop falling for "high-protein" health halos in the grocery store.
Explore More from Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: tiktok.com/@drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX: x.com/drgabriellelyonApply to become a patient: https://drgabriellelyon.com/new-patient-inquiry/Weekly newsletter: https://institute-for-muscle-centric-medicine.ck.pageOrder my new book: https://www.amazon.com/exec/obidos/ASIN/1668085623Chapters:
00:00 - Introduction & Protein Summit
02:30 - Amino Acids Beyond Muscle
05:55 - Minimum vs. Optimal Protein
08:13 - Lab Studies vs. Real Life
10:33 - Context & Individual Needs
12:04 - The Fortification Trap
14:41 - The Whole Food Matrix
16:18 - Research Funding & Transparency
18:00 - The Future of Protein
Disclaimer:The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 15 Oct 2026 - 21min - 246 - Dr. Tiffany Moon: Is Anesthesia Safe? What Patients Fear vs. What Actually Happens
In this episode, board-certified anesthesiologist, researcher, and former Real Housewives of Dallas star Dr. Tiffany Moon pulls back the curtain on modern medicine, surgical pain management, and the reality of navigating elite academia. From addressing widespread public fears around clinical fentanyl use to detailing why she was branded an "embarrassment" by academic peers for appearing on reality television, Dr. Moon speaks candidly about breaking stereotypes, the gender pay gap in healthcare, and using a massive public platform to advocate for science and mentorship.
What You'll Learn In This Episode:
The Clinical Truth About Fentanyl: Why it is the standard of care for 90% of surgeries, and why post-op patients shouldn't fear becoming addicted.The Reality TV Fallout: How appearing on The Real Housewives led to institutional blowback—and why she’d do it again.Leveraging Fame for Science: Turning pop culture visibility into serious advocacy for mentorship, healthcare equity, and closing the gender pay gap.Shattering Stereotypes: Moving past appearances to run clinical trials, publish randomized controlled studies, and teach the next generation of physicians.Thank you to our sponsors:
Cozy Earth: cozyearth.com Use code DRLYON for 20% offOur Place: fromourplace.com Use code DRLYON for 10% offBranch Basics: branchbasics.com Use code DRLYON for 15% off Premium Starter KitExplore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patientFind Dr. Tiffany Moon at:
Instagram: instagram.com/tiffanymoonmd (@tiffanymoonmd)TikTok: tiktok.com/@tiffanymoonmd (@tiffanymoonmd)YouTube: youtube.com/@TiffanyMoonMDOfficial (@TiffanyMoonMDOfficial)Website: tiffanymoonmd.comFacebook: facebook.com/tiffanymoonmd (@tiffanymoonmd)X (Twitter): x.com/TiffanyMoonMD (@TiffanyMoonMD)Connect with Dr. Gabrielle Lyon:
Instagram: / drgabriellelyonTikTok: / drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: / doctorgabriellelyonChapters
00:00 – The Truth About Fentanyl in Surgery
01:18 – Breaking Stereotypes in Academic Medicine
12:00 – Pain Protocols, Anesthesia Safety & Clinical Trials
25:00 – Reality TV, Academic Backlash & Healthcare Equity
40:00 – Career Reinvention & Overcoming Physician Burnout
1:00:00 – Why Preventive Medicine Is the Future
1:08:39 – Longevity Medicine, GLP-1s & Muscle Health
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers:This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 13 Oct 2026 - 1h 08min - 245 - Hormones and Attraction: What We Think We Know vs. What the Science Says
Can you tell someone's testosterone or estrogen levels just by looking at their face? Is "jawmaxxing" actually backed by science? In this video, we dive deep into the real science of hormones, physical attraction, and evolutionary biology.
We debunk popular myths around high testosterone, facial masculinity, and ovulation preferences, revealing what the research actually shows about human mate selection. Discover why facial structure isn't a hormone panel, how estrogen impacts skin and collagen as women age, and why physical strength accounts for 70% of perceived bodily attractiveness.
If you want to understand how hormones shape our development—and why muscle is the single most modifiable signal of health and longevity—this episode is for you.
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: tiktok.com/@drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- YouTube: youtube.com/@DrGabrielleLyon
- X: x.com/drgabriellelyon
- Apply to become a patient: https://drgabriellelyon.com/new-patient-inquiry/
- Weekly newsletter: https://institute-for-muscle-centric-medicine.ck.page
- Order my new book: https://www.amazon.com/exec/obidos/ASIN/1668085623
Chapters:
00:00 What role do hormones play in the traits we find attractive?
00:46 High vs. low testosterone: does it change who we pick?
01:44 The ovulation story: do women seek out masculine men?
03:19 Two questions: can you see hormones, and what's modifiable?
04:12 What testosterone and estrogen build during development
05:23 Does winning raise testosterone? What a masculine face tells you
06:26 Selection, training and genes: why muscle isn't just testosterone
07:54 Are women attracted to testosterone? What the longitudinal studies show
09:29 Face vs. strength: what predicts mating success
10:08 The 70% finding: strength and bodily attractiveness
11:44 Why strength is a hard-to-fake health signal
13:41 Can you see estrogen? Facial ratings and why more isn't better
14:41 Culture moves beauty standards, and estrogen shows up in skin
16:08 Estrogen therapy and skin: what it can and can't do
16:36 Can you see hormones? Muscle is the system you can see and change
Disclaimer:The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 08 Oct 2026 - 17min - 244 - Dr. JJ Thomas: Pain Is an Alarm. Why Your Injury Keeps Coming Back and How To Fix It
When you have musculoskeletal pain, the natural instinct is to try and treat it directly. But the cause of that pain often starts somewhere else in the body.
I learned that from this week's guest, Dr. JJ Thomas, who is my physical therapist and good friend. She was my patient first, and now we are each other's patients. She has practiced physical therapy for more than 25 years and has worked with the Philadelphia 76ers, the Philadelphia Eagles, and athletes from the UFC and US Olympic programs.
What you'll learn in this episode:
Why a chronic tendon injury can come right back, even after eccentric loading or PRPWhether a frozen shoulder in menopause is a hormone problem, and one of the first movements Dr. Thomas checksWhy she works lying on her stomach, and the 10-minute band routine she wrote for an eight-hour desk dayWhy sitting up taller won't fix your posture, and what poor posture tells her about your bodyWhy she gives patients shoulder blade exercises for their pelvic floorHow much a standard squat does for your posterior chain, and the position she wants you in more oftenWhy she believes “overuse” injuries are often underuse injuries, and how that changes the way she treats shin splintsWhy needling a clinician's quad and adductors normalized his neck rotationWhat her blood work showed after years of hard training, and the nutrition change she calls her “game changer”Thank you to our sponsors:
• Manukora - Get 31% off at https://www.manukora.com/drlyon
• Timeline - up to 20% off when you subscribe and save at https://www.timeline.com/lyon
• Bon Charge - Use code DRLYON for 15% off at https://www.boncharge.com
Explore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insightshttps://drgabriellelyon.com/sign-up/
Apply to become a patient: Personalized care with Dr. Lyon’s clinical teamhttps://drgabriellelyon.com/new-patie...
Find Dr. JJ Thomas at:
• YouTube: https://www.youtube.com/@drjjthomas
• Website: https://primalphysicaltherapy.com/
• Instagram: https://www.instagram.com/drjjphysicaltherapist/
Connect with Dr. Gabrielle Lyon:
• Instagram: https://www.instagram.com/drgabriellelyon/
• TikTok: https://www.tiktok.com/@drgabriellelyon
• Facebook: http://facebook.com/doctorgabriellelyon
• X: http://x.com/drgabriellelyon
• Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
• Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters
00:00 – Posture Myths & Why Sitting Up Straight Fails
02:18 – Treating Root Causes vs. Bandaging Pain
06:48 – The Hazards of Sitting & Reframing Movement as Health
13:39 – The 7 Primal Movement Patterns Every Body Needs
25:28 – Scapular Stability, Pelvic Health, and Primal Movements
39:12 – Fixing Glute Amnesia & Activating the Posterior Chain
51:57 – Why "Overuse" Injuries Are Really Underuse Problems
58:34 – Dry Needling & System-Based Movement Resets
1:13:53 – Dialing in Hormones, Protein, and Metabolic Health
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 06 Oct 2026 - 1h 30min - 243 - Is It Too Late to Build Muscle in Menopause? No. Here's What the Studies Show
Will I get too bulky?" No. "Is it too late?" Also no. Here's the context: during the menopause transition, women lose lean mass, gain fat, and their muscle becomes harder to build — the same workout and the same protein meal produce less than they did at 30. For years the only conversation has been hormone therapy, yes or no, as if that were the fix. In Part 2 of her menopause series, Dr. Gabrielle Lyon looks at what the evidence actually says builds muscle back.
In this episode:
-Postmenopausal women can build muscle and strength at any age (Frontiers in Endocrinology)
- Up to 8 lbs of skeletal muscle in 12 weeks (J Nutr Health Aging RCT)
- Anabolic resistance: why the same workout and the same meal produce less after menopause
- "I was wrong": hormone therapy vs. lifting, and the conversations with Dr. Donald Layman
- HRT alone and lean mass: a 0.06 kg difference across 12 trials
- Estradiol plus training: bigger quad and fat-free mass gains, maintained at 12 months
- Lift first — the practical translation while the HRT evidence evolves
- Why protein matters more after menopause, and why 60 g spread thin isn't enough
- The RDA (0.8 g/kg) isn't enough to protect bone; ESCEO's 1–1.2 g/kg floor
- Doubling protein to 1.6 g/kg: more fat lost, more lean mass kept
- The 6-step Forever Strong menopause protocol
Sponsor
David Protein — 28 g of protein, 150 calories, zero sugar → davidprotein.com/drlyon, subscribe to save 10% on every order
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: tiktok.com/@drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
00:00 Will I get too bulky? Is it too late? Both answers are no
01:09 Postmenopausal women gained up to 8 lbs of muscle in 12 weeks
02:24 Anabolic resistance: more volume, more intensity, more protein
03:34 Hormone therapy or lifting? "I was wrong"
05:16 HRT alone and lean mass: 0.06 kg across 12 trials
06:16 Estradiol amplifies training — it doesn't replace it
07:22 Lift first: what to do while the evidence evolves
10:21 Why protein matters more after menopause (and why 60 g isn't enough)
11:16 The RDA won't protect your bones: the 1–1.2 g/kg floor
12:16 Doubling protein: more fat lost, more lean mass kept
13:22 The Forever Strong protocol, step 1: train 2–3 days a week
14:15 Steps 2–3: 30–50 g protein at first and last meal, impact and loading
15:13 Steps 4–6: hormone therapy with training, body composition, blood work
16:07 You're not alone: the Menopause Challenge
Disclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.
Thu, 01 Oct 2026 - 17min - 242 - How to Prepare Your Body for Surgery: Protein, Prehab and the 5 Days That Change Your Recovery | Dr. Rebecca Knackstedt
Most patients are told one thing before surgery: stop all supplements. Duke surgeon Dr. Rebecca Knackstedt says that blanket advice can do harm, and that what you do in the days before surgery changes how you heal.
Dr. Knackstedt is a plastic and reconstructive microsurgeon on faculty at Duke, an MD-PhD researcher and a certified functional medicine provider whose research focuses on surgical prehabilitation: preparing the body, mind, and home before surgery, the way we already do with rehab.
In today’s episode, we discuss:
• What prehab looks like for any operation
• The labs she checks
• Which supplements to keep and which to stop (omega-3s do not increase bleeding)
• Hormones after breast cancer
• Why mammograms still beat thermography
• What chemo does to metabolism
• The questions to ask your oncologist before a treatment decision
• How much protein to eat (no standard exists, and the average woman gets 60 to 70 grams a day, well short of the 100-gram floor)
• Why surgery is catabolic and muscle is your reserve
• Carbohydrate loading before the fasting cutoff and why it can reduce pain
• The five-day window that lowered complications and even mortality in head and neck cancer patients
• Why early walking replaced routine bed rest
Connect with Dr. Knackstedt
Instagram → https://www.instagram.com/surgical_recovery/
Website → https://www.clararecovery.com/
Sponsors
• Perfect Amino by BodyHealth, https://bit.ly/4wZgg6N, code LYON20 for 20% off your first order
• Timeline Mitopure → https://bit.ly/4x18cm5, for an extra 20% off
• Lola Blankets → lolablankets.com (http://lolablankets.com/), code: DRLYON for 40% off select blankets (limited time)
Find Dr. Gabrielle Lyon at:
• Instagram: https://www.instagram.com/drgabriellelyon/
• TikTok: tiktok.com/@drgabriellelyon
• Facebook: http://facebook.com/doctorgabriellelyon
• X: http://x.com/drgabriellelyon
• Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
• Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
Chapters:
00:00 Prehab saves lives and money. So why isn't it standard of care?
01:05 Meet Dr. Rebecca Knackstedt: Duke microsurgeon and functional medicine provider
05:35 The patient who changed everything, and why good surgery isn't enough
08:34 What prehab is, and the exercises to do before any surgery
12:14 Hormones after breast cancer, rising rates in young women, and real risk factors
18:42 Chemo, metabolic syndrome and why body composition matters
23:13 The end of bed rest, and the labs that matter before surgery
27:04 Mammograms vs. thermography, and absolute vs. relative risk
34:12 Protein before surgery: 2 g/kg, track 3 days, never under 100 g
38:43 Supplements to take, and why "stop all supplements" is wrong
44:40 Preparing the mind: anxiety, sleep, anesthesia depression, expectations
51:21 Red light, saunas, hyperbaric oxygen, wound vacs, scars and pain control
1:04:59 Surgery is catabolic: muscle as your glucose reserve
1:07:34 Carb loading, the 5-day window, probiotics and the surgery go-bag
1:14:15 Why prehab isn't standard of care yet, and why she's hopeful
Disclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.
Tue, 29 Sep 2026 - 1h 17min - 241 - Menopause Is a Muscle Problem, Not Just a Hormone Problem
Menopause is changing your body, but the part nobody talks about isn't hot flashes. It's muscle. Women lose lean mass fastest in perimenopause, the loss probably starts closer to 35, and no pill, patch or injection fixes it.
In this solocast, Dr. Gabrielle Lyon explains what estrogen, testosterone and FSH actually do to your metabolism, why a 50-year-old body can still build muscle, and the training and protein protocol to start now.
Join the Menopause Challenge →
https://drgabriellelyon.com/menopause-challenge/
[Use Code 25OFF through Sept 27]
Thank you to our sponsors:
- Rula, therapy covered by insurance → rula.com/drlyon
Find Dr. Gabrielle Lyon at:
- Instagram: https://www.instagram.com/drgabriellelyon/
- TikTok: @drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- YouTube: youtube.com/@DrGabrielleLyon
- X (Twitter): x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
- Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623
Chapters:
00:00 Menopause is changing your body — but it doesn't have to change your life
00:59 The suitcase story: today is about muscle, not hot flashes
01:47 Hormone therapy, yes or no? Why that's the wrong first question
03:36 What menopause is, when it arrives, and 40% of your life after it
04:37 When lean mass really starts to fall — and why testing misses it
06:46 Testosterone vs. estrogen: no two women go through it the same way
08:40 Anabolic resistance: why the muscle-building switch gets sticky
10:31 Estrogen, joints and injury risk (Dr. Jocelyn Wittstein)
13:27 Less muscle, nowhere to put carbs: the lean prediabetic patient
14:19 Falls, fractures, heart disease, and muscle as an early bone signal
16:14 Visceral fat, energy expenditure, fat oxidation and FSH
18:02 Test your blood — and pull the levers you control
19:00 The starting protocol: 2–3 days a week and the movements to keep
20:30 Menopause changes your body, not your life — the Menopause Challenge
Mentioned
- Dr. Jocelyn Wittstein on estrogen, joints and injury risk → https://youtu.be/ILyzNTjZTGI
- Juliet & Dr. Kelly Starrett on floor sitting and mobility → https://youtu.be/QOjzh-711Q0
- SWAN (Study of Women's Health Across the Nation)
- The Lancet Diabetes & Endocrinology review on lean mass and chronic disease
- ESCEO guidance on muscle and bone
Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 24 Sep 2026 - 22min - 240 - ED Predicts Heart Attacks Better Than Chest Pain: The 2 Tests to Ask For | Dr. Tobias Kohler
Your testosterone number matters at every age, but most men never learn what theirs should be. Mayo Clinic urologist Dr. Tobias Kohler explains why ~500 is the target, why 1,000 is already running hot, what 2,000+ does to the heart, and why a randomized trial found lifting without steroids beat steroids without lifting. Plus: the blood test that catches heart risk your cholesterol panel misses.
Dr. Kohler returns for his second appearance (his first, on erections, testosterone and muscle mass, is one of the most-watched episodes in the show's history). This time: why men's longevity is roughly 50 years behind women's; the Princeton IV consensus he co-chaired, which treats ED as one of the strongest predictors of a future heart attack and points young men toward a coronary calcium scan; the 0–12 ceramide blood test that changes with your behavior; how to get a testosterone baseline that actually means something; what redlining to 2,000–3,000 does to the heart, the set point and the skin; Peyronie's disease, Viagra vs. Cialis, the pills-to-implant ladder, sexual rehab after prostate surgery, and a patient who got stronger with zero testosterone.
About Dr. Tobias Kohler
Tobias S. Kohler, MD, MPH, is Professor of Urology at Mayo Clinic, a fellowship-trained andrologist with 25+ years of clinical and surgical experience and 250+ peer-reviewed publications. He co-chaired the Princeton IV Consensus Guidelines on ED and cardiovascular disease, co-founded the EROS penile implant registry, and co-edited Contemporary Treatment of Erectile Dysfunction (2nd ed.).
🙌 Thank you to our sponsors:
Cozy Earth - Get 20% off at https://bit.ly/3RLZNEv
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📺 Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
📱 Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
TikTok: https://bit.ly/3OFK3kJ
X.com: https://bit.ly/4l3YlaX
Facebook: https://bit.ly/3MBrJso
LinkedIn: https://bit.ly/3N1nrdL
Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Chapters
00:00 Men are dying earlier than women the penis is the check-engine light
03:26 Boys stop seeing doctors for 20 years the case for an Office of Men's Health
10:57 Princeton IV: ED predicts heart attacks, calcium scans, and Cialis
12:44 The ceramide blood test your cholesterol panel can't replace
20:37 Cardiac risk calculators, statins, and what your LDL should be
25:38 GLP-1s, fertility, and "what's the risk of doing nothing?"
29:05 Testosterone: the ~500 target, why 1,000 runs hot, what 2,000+ does to the heart
31:44 Check your testosterone at 25 and why steroids won't make you a pro
36:57 Tolerance and the new set point redlined men can't escape
38:13 The 1980s trial: lifting without steroids beat steroids without lifting
42:06 Steroid cocktails, arrhythmias, irreversible side effects, and the sarcopenia trade-off
53:04 Peyronie's disease and Viagra vs. Cialis
57:32 Penile implants: the knee-replacement analogy and the pills-to-surgery ladder
1:02:27 Sexual rehab after prostatectomy and the questions to ask before cancer treatment
1:07:55 Closing: be proactive and the patient who got stronger with zero testosterone
Disclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.
Tue, 22 Sep 2026 - 1h 11min - 238 - The Truth About Testosterone in Women
You say "steroids" and picture a baseball scandal, a jacked guy, a bad spray tan. But cortisol is a steroid. Estrogen is a steroid. The cream you put on poison ivy is a steroid. The word covering all of them is also covering testosterone therapy for women, and that collision is quietly costing women muscle and bone they don't have to lose.
In this solo episode, prompted by a magazine interview on steroid use in women, Dr. Gabrielle Lyon breaks down what these molecules actually are, what they do inside a cell, and why the line between medicine and misuse has nothing to do with the word "steroid."
Study and References:
The Effects of Supraphysiologic Doses of Testosterone on Muscle Size and Strength in Normal Men (Bhasin et al., NEJM 1996) - https://pubmed.ncbi.nlm.nih.gov/8637535/
Testosterone Enhances Estradiol's Effects on Postmenopausal Bone Density and Sexuality (Davis et al., 1995) - https://pubmed.ncbi.nlm.nih.gov/7616872/
Global Consensus Position Statement on the Use of Testosterone Therapy for Women (2019) - https://pubmed.ncbi.nlm.nih.gov/31498...
ISSWSH Clinical Practice Guideline for the Use of Systemic Testosterone for HSDD in Women (2021) - https://pubmed.ncbi.nlm.nih.gov/33814...
The Global Epidemiology of Anabolic-Androgenic Steroid Use: A Meta-Analysis (Sagoe et al., 2014) - https://pubmed.ncbi.nlm.nih.gov/24582...
What Is the Prevalence of Anabolic-Androgenic Steroid Use Among Women? A Systematic Review (Piatkowski et al., Addiction, 2024) - https://onlinelibrary.wiley.com/doi/1... "
The Compounds for Females Are Really Commonly Faked!": Women's Challenges in Anabolic Steroid Acquisition (Piatkowski et al., Drug and Alcohol Review, 2024) - https://onlinelibrary.wiley.com/doi/1...
Explore More from Dr. Gabrielle Lyon:
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team https://drgabriellelyon.com/new-patie...📱 Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
TikTok: https://bit.ly/3OFK3kJ
X.com: https://bit.ly/4l3YlaX
Facebook: https://bit.ly/3MBrJso
LinkedIn: https://bit.ly/3N1nrdL
Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
📺 Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
⏰ Chapters:
00:00 - Beginning
01:25 - Introduction: The Sister Who Says "Oh My Gosh, You're Taking Steroids" Why Medicine Needs a Shared Vocabulary
03:43 - What a Steroid Actually Is: Four Rings of Carbon
04:49 - Anabolic vs. Androgenic: Same Receptor, Different Effects
06:16 - A Brief History: From Wasting Disease to the Weight Room
08:59 - Restoring vs. Exceeding: Why the Range Is the Whole Game
11:38 - The Davis Trial: Testosterone, Bone Density, and Lean Mass
13:38 - Oral Compounds, the Liver, and Why Conversion Matters
14:20 - What Gets Sold Isn't What's Labeled: The Australian Drug-Checking Data
15:31 - The 1.6% vs. 4% Myth: Reading the Prevalence Data Correctly
18:33 - Why GLP-1s Are Pushing Women Toward Androgens
20:26 - Permanent Effects: Voice Changes and What the Literature Shows
21:33 - The Four Questions to Ask Before Any Androgen Conversation
24:25 - Closing: Entering the Sarcopenia Era
‼️ Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 17 Sep 2026 - 25min - 237 - Fathers Lose Testosterone When They Raise Their Kids | Aldrich Chan, Psy.D.
Most people assume becoming a parent is an emotional change, but a measurable part of it is hormonal, and it happens in fathers too. I sat down with Aldrich Chan, Psy.D., to talk about what changes in the brain, why the split we draw between mind and body does not hold up, and what decides whether stress reads as manageable or overwhelming when the hormones are identical either way.
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https://www.drchancnc.com/books
📱Connect with Aldrich Chan, Psy.D
Website: https://www.drchancnc.com/
YouTube: www.youtube.com/@draldrichan
Instagram: https://www.instagram.com/draldrichan
Facebook: https://www.facebook.com/draldrichan
LinkedIn: https://www.linkedin.com/in/draldrichan/
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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📱Connect with Dr. Gabrielle Lyon:
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Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 - Introduction: what a neuropsychologist measures
03:25 - Mild cognitive impairment and proactive interference
04:52 - The SAD theory: separation, alienation, discord
06:30 - The default mode network and 46.9% mind wandering
08:56 - Reframing ADHD as an evolutionary advantage
18:21 - Evolutionary mismatch and hunter-gatherer comparisons
21:03 - Neuroplasticity, epigenetics, and the 24-hour timeline
24:29 - Mind-body dualism and the gut-brain connection
31:31 - What fatherhood does to the brain and testosterone
36:47 - Choice overload and the four-bit working memory limit
39:54 - Temporal discounting and building immediate feedback
43:23 - Vital signals and how to identify a core value
49:49 - Intuition, somatic markers, and the vmPFC
55:00 - The 20-watt brain versus a 10-gigawatt supercomputer
01:02:58 - Only 35% of the brain is built at birth
01:06:13 - Creativity, nothingness, and the fear of uncertainty
01:16:31 - Process, flow states, and the jazz pianist studies
01:22:53 - Mirror neurons, group selection, and the rat experiments
01:34:20 - Eustress and the line between moderate and major stress
01:44:39 - Alloparenting and what the Hadza numbers show
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 15 Sep 2026 - 1h 46min - 236 - The Bone You Have At 50 Was Built Before You Turned 18
You might think bone density is something you build slowly over a lifetime, but nearly all of your peak bone mass is set before age 18, in a four-year window most parents never see coming. In this solo episode I break down what happens to a child's skeleton during that window, what GLP-1 medications do inside a body that's still growing, and the protocol I'd want every parent to follow. Muscle and bone are not what a body has they're what a body was built to become.
In this solo episode, Dr. Gabrielle Lyon breaks down the science of bone health in children, adolescent GLP-1 use, and muscle building in kids:
Why the four years around age 12 in girls and 14 in boys account for close to 40% of the total bone mineral a person will carry for lifeWhy a hip fracture in a healthy 29-year-old is almost always a story about a childhood building phase that never happened, often tied to a history of restriction like anorexiaWhat semaglutide and other GLP-1 medications do inside a still growing skeleton, and why no long term bone density data exists for adolescents on these drugsWhy a JAMA Network Open trial found the group combining liraglutide with resistance training lost the most weight with bone mineral density statistically unchanged, while the drug alone caused bone lossThe complete protocol for parents: track strength and function over the scale, muscle strengthening and bone loading exercise three days a week each, protein at breakfast, and a screen time floor instead of a ceilingMuscle and bone are not what a body has; they are what a body was built to become, and childhood is the only window that bone accrual and muscle development happen. Understanding pediatric bone health, sarcopenia in children, and the real research on GLP-1s and adolescents is the difference between guessing with your child's skeleton and protecting it on purpose.
Study and References:
Sarcopenic Obesity in Children -https://pubmed.ncbi.nlm.nih.gov/41995008/Sedentary Behaviors in Today's Youth (AHA) -https://www.ahajournals.org/doi/10.1161/CIR.0000000000000591Semaglutide and Body Composition (STEP 1) -https://pmc.ncbi.nlm.nih.gov/articles/PMC8089287/Peak Bone Mass Position Statement (NOF) -https://pubmed.ncbi.nlm.nih.gov/26856587/Bone Health After Exercise vs GLP-1 Treatment -https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2820308Resistance Training in Kids: An Umbrella Review -https://pubmed.ncbi.nlm.nih.gov/32757164/Thank you to our sponsors:
Timeline - up to 20% off when you subscribe and save at https://bit.ly/4x18cm5BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4wZgg6NBranch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4i6iOfK with the code DRLYON.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
00:44 - The 29-Year-Old Who Fractured Her Hip
01:20 - Muscle and Bone Are Childhood Assets
03:01 - The Question I Keep Getting From Patients
03:39 - The 30-Year Lifting Debate Is Over
04:23 - Sarcopenic Obesity: More Muscle, Less Strength
07:01 - What a Mouse Model Reveals About Muscle Potential
08:24 - Screens: What the Data Shows
10:00 - Food, Sleep, and the Screen-Weight Loop
12:38 - GLP-1s in Teens: The STEP TEENS Trial
13:52 - The Muscle Framing Mistake Everyone Makes
16:49 - The Four-Year Window Bone Gets Built
18:02 - The Trial That Proves Exercise Protects Bone
20:29 - Prescribing Into an Unstudied Window
20:46 - Why Lifting Doesn't Stunt Growth
21:49 - Kids Get Stronger Without Building Muscle
22:29 - The Protocol: What to Do Starting Today
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 10 Sep 2026 - 24min - 235 - The Testosterone Myth Women Have Been Lied To About │ Dr. Susan Hardwick-Smith
You have probably been told that testosterone is a male hormone. Women produce more of it than estrogen, and for many of us it is the first hormone to go, sometimes reading zero five years before menopause while periods are still regular. Dr. Susan Hardwick-Smith and I get into what that costs you in muscle and bone, why there are thirty-one approved testosterone products for men and none for women, and what the number on your own lab report is measuring.
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Create Her: Aging into the Healthiest Version of Yourself by Susan Hardwick-Smith MD https://www.amazon.com/Create-Her-Healthiest-Version-Yourself/dp/1637636644/ref=sr_1_3?s=books&sr=1-3
Dr. Gabrielle Lyon with Amy Pearlman Podcast
Connect with Dr. Susan Hardwick-Smith
Website: drsusan.com
YouTube: https://www.youtube.com/@drsusan
Instagram: https://www.instagram.com/drsusanofficial
TikTok: https://www.tiktok.com/@drsusanofficial
Facebook: https://www.facebook.com/drsusanofficial/
LinkedIn: https://www.linkedin.com/in/drsusanhardwicksmith/
Thank you to our sponsors:
Timeline - up to 20% off when you subscribe and save at https://bit.ly/4x18cm5BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4wZgg6NBranch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4i6iOfK with the code DRLYON.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonTimestamps:
00:00 - Introduction: testosterone in women
03:00 - Eighteen years in OB-GYN and the practice she left
04:57 - Thirty years in medicine, zero training on testosterone
06:40 - 31 FDA-approved products for men, zero for women
07:35 - Why women produce more testosterone than estrogen
09:20 - What the ovaries stop making at menopause
10:18 - Testosterone reading zero five years early
11:41 - Low testosterone symptoms in women
13:22 - Intrinsa, the 2004 patch the FDA turned down
19:04 - Off-label prescribing and what FDA approval means
21:35 - Cognition, breast cancer, muscle and bone
25:33 - Osteoarthritis and the anti-inflammatory theory
26:31 - Dosing fears: hair loss, acne, voice changes
28:16 - Why gels are dosed ten times higher
32:14 - The 2019 international consensus
34:00 - Dividing a 50 mg tube by ten
38:18 - The Baylor study: pellet versus gel at six weeks
40:13 - Safety data from fifty years of transgender care
45:03 - Eight years of high dosing and what it cost
46:16 - Lab reference ranges versus optimal ranges
48:28 - ELISA versus LC-MS, and what the study found
51:07 - Why free testosterone is calculated, not measured
57:58 - Tachyphylaxis and chasing the number
1:01:39 - Pellets, BioTE and where the reputation came from
1:06:33 - Delivery methods, cypionate and enanthate
1:11:47 - Whether anything raises testosterone naturally
1:13:03 - DHEA at 100 mg and what it moved
1:17:07 - Drugs that lower testosterone in women
1:20:55 - Closing thoughts on dosing and access
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 08 Sep 2026 - 1h 21min - 234 - 5 Protein Myths Your Doctor Is Still Repeating In The Exam Room
You probably ate something today with high protein printed across the front of it, and there is a good chance it did almost nothing for your skeletal muscle. There is no meaningful enforcement standard for what the front of a package is allowed to promise, and the research points to a per meal threshold most of these products do not come close to touching. Here is the number, the five myths that have to come off the table first, and how to read any label in about five seconds.
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Egglife - Find egglife wraps chillin’ in the fridge at Aldi, Whole Foods, Kroger, Target, Walmart & more - Visit https://bit.ly/4yxBs5l to find a retailer near you,Timeline - up to 20% off when you subscribe and save at https://bit.ly/4cNXeJq Bon Charge - Save 15% at https://bit.ly/3UsB1KI with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: what a high protein label promises
01:03 - Protein-ification and the labeling gap
04:10 - Myth 1: protein and kidney function
06:01 - Myth 2: the 0.8 gram RDA
07:04 - Nitrogen balance and the 2026 guideline change
07:45 - Where the clinical target lands above the RDA
08:43 - Myth 3: acid ash and bone density
11:01 - Myth 4: leucine and the per meal threshold
12:12 - Four product categories in your pantry
14:44 - The 25 to 30 gram complete protein rule
15:08 - Myth 5: daily total versus per meal distribution
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 03 Sep 2026 - 16min - 233 - STOP Treating Low Testosterone As Depression: The 160 Reading Navy Doctor Refused | Tim Parlatore
A Navy captain with 24 years of service went to medical for exhaustion, weight gain, and low mood, and was told to see a therapist and eat less. When he asked for a testosterone test his physician asked whether he had erectile dysfunction, and refused to order it when he said no. His level came back at 160; the cutoff we use in this country is 300. I've treated this population for 15 years, and roughly 27% of operators test below that number. Tim Parlatore is the attorney who wrote the Pentagon memo that now puts testosterone on the annual physical, and we get into what it says and why most men never have this hormone checked again after they leave pediatrics.
Studies & References
Cardiovascular Safety of Testosterone-Replacement Therapy - https://pubmed.ncbi.nlm.nih.gov/37326322/You Can Conquer Trauma and PTSD with Chris Frueh, PhD - https://www.youtube.com/watch?v=0olunOZM2lcSupport Kaczkowski Family's GoFundMe campaign
https://impact.navysealfoundation.org/campaign/827807/donate?utm_source=ig&utm_medium=social&utm_content=link_in_bioWant ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSRe
📱Connect with Tim Parlatore:
Website: https://parlatorelawgroup.com/
YouTube: https://www.youtube.com/channel/UCSSQE0_WrlegQk09nFi4QZw
Instagram: https://www.instagram.com/tparlatore/
Facebook: https://www.facebook.com/tparlatore
X.com: https://x.com/timparlatore
LinkedIn: https://www.linkedin.com/in/timothy-parlatore/
🙌Thank you to our sponsors:
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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📱Connect with Dr. Gabrielle Lyon:
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Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 - Intro of show
02:32 - Why military service lowers testosterone
04:15 - Treated like an anabolic steroid
06:52 - Screening first, not bodybuilding
08:07 - 27% of operators test low
09:34 - The three groups of users
10:52 - The BUD/S student who died
13:00 - A captain's testosterone was 160
15:39 - Denied the test, then the wait
18:58 - Why men skip baseline testing
19:46 - Beyond operators: the wider force
21:56 - The three effects on the force
26:37 - The best biomarker for men
27:40 - Why they wanted a study first
29:04 - Health, media, and politics
37:44 - Testing and treating women
44:57 - Voluntary treatment and options
48:20 - The friend Tim lost
51:00 - Selling the science to the Pentagon
53:00 - Building a research dataset
1:05:29 - Naval Academy to defending Gotti
1:11:54 - Trial as psychological warfare
1:21:03 - The fitness turnaround
1:26:02 - The email spying scandal
1:31:06 - "I am the storm"
1:35:32 - Prosecutorial misconduct
1:41:11 - Secondary trauma and the human cost
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 01 Sep 2026 - 1h 45min - 232 - Nobody Told You This About Creatine
You might think creatine is a bodybuilder's steroid you have to cycle, load, and fear for your kidneys, but it's a compound your own body already makes from three amino acids, with one of the deepest safety records in all of nutrition science. The problem isn't the creatine; it's the noise around it.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why the bump creatine causes in your creatinine lab value is a metabolic artifact, not a sign of kidney damage in healthy peopleWhere the hair-loss fear came from. A single unreplicated study in one rugby player showing a 56% DHT rise, and why no research has ever directly linked creatine to hair lossHow men and women respond differently (roughly 1.5 kg of lean mass in men vs. about a third of a kilogram in women), and why women still gain real strength, grip, cognition, and recoveryWhy you can't realistically eat your way to 5 grams a day: it would take 2.5 to 3 pounds of cooked meat and fish daily, so a single scoop closes the gapThe protocol: 3–5 grams of plain monohydrate every day, no loading phase, no cycling, timing barely mattersMuscle is your organ of longevity, the tissue that clears most of the glucose in your bloodstream and defends your metabolism as you age. Creatine won't build it for you, but it raises the ceiling on the work you can do, so the training that protects that muscle pays off more. Understanding what's real and what's fearmongering is the difference between avoiding a proven tool and using it well.
Studies & References
PubMed study: https://pubmed.ncbi.nlm.nih.gov/1327657/Sports Nutrition Society: https://www.sportsnutritionsociety.org/Thank you to our sponsors:
Egg life - CTA - Find egglife wraps chillin’ in the fridge at Aldi, Whole Foods, Kroger, Target, Walmart & more - Visit https://bit.ly/3UghRHV to find a retailer near youBodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4gP6VtpOneSkin - Get 15% off at https://bit.ly/4xpFWuE with code DRLYONDavid Bars - Subscribe and save 10% on every order’ at https://bit.ly/4zAflMBExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
02:47 - What Creatine Is and Isn't
03:24 - The Phosphocreatine Energy System
04:22 - Lean Mass: Water and Training Capacity
05:08 - Men vs Women Respond Differently
06:29 - Vegans, Older Adults, and Sarcopenia
07:11 - Creatine and the Brain
08:53 - The Real Safety Profile
09:31 - The Kidney and Creatinine Myth
09:57 - The 56% DHT Hair Loss Claim
10:37 - Contraindications and Screening
12:19 - Why You Can't Eat Enough Creatine
14:26 - Muscle-Centric Medicine
16:44 - How to Dose It Correctly
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 27 Aug 2026 - 19min - 231 - Are You Aging Faster Than You Should? - Dr. Kristen Holmes
Most of what we call "aging" may not be about time at all. It may be a nervous system stuck in stress, quietly draining your sleep, your recovery, and your long-term health.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Kristen Holmes to discuss:
Why the hallmarks of aging- inflammation, mitochondrial dysfunction, cellular decline may be symptoms of a dysregulated autonomic nervous system, and how much of your HRV (47–65%) is genetic versus trainableHow your sleep is decided during the day, not at night, and why perceiving your day as "threatening" keeps your HRV suppressed and robs you of deep, restorative sleepThe circadian "amplitude" formula for bright days and dark nights that predicts everything from menopause symptom severity to longevity, plus the ~90 minutes of natural light almost no one getsWhy late-night eating rivals alcohol for damaging your resting physiology, and how a simple 12-hour eating window gets you most of the way thereWhy the fittest people sleep less, and how all-day movement and "exercise snacks" beat a single gym blockWhen you understand that your nervous system sits underneath your sleep, energy, and pace of aging, you stop chasing fragmented fixes and start pulling the few daily levers light, movement, meal timing, consistency that move the needle.
Studies & References
Stress and Heart Rate Variability: A Meta-Analysis and Review of the Literature — https://pmc.ncbi.nlm.nih.gov/articles/PMC5900369/How to Improve Your Circadian Rhythm with Satchin Panda PhD: https://youtu.be/gM_b4t0ARG8?si=QKfpYEAh1O5lyMw8Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSRe
Listen to “The Line” on all your favorite platforms!
YouTube: https://www.youtube.com/@TheLine-Podcast
Apple Podcasts: https://podcasts.apple.com/us/podcast/the-line-with-dr-kristen-holmes/id1846864184
Spotify: https://open.spotify.com/show/3zc3BCKHlFAlffRnd6kZXy
Get Dr. Kristen Holmes’s book, “Aligned” here: https://sites.prh.com/dr-kristen-holmes
📱Connect with Dr. Kristen Holmes:
Website: https://drkristenholmes.com/#top
YouTube: https://www.youtube.com/@TheLine-Podcast
Instagram: https://www.instagram.com/drkristenholmes/
LinkedIn: https://www.linkedin.com/in/kristen-holmes/
🙌Thank you to our sponsors:
Egg life - CTA - Find egglife wraps chillin’ in the fridge at Aldi, Whole Foods, Kroger, Target, Walmart & more - Visit https://bit.ly/3UghRHV to find a retailer near you
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OneSkin - Get 15% off at https://bit.ly/4xpFWuE with code DRLYON
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
📱Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
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Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 - Intro of show
02:44 - Two types of people
03:01 - Aging as nervous system dysregulation
04:49 - The stellate ganglion block and trauma
07:34 - How much of HRV is genetic
11:13 - Emotions of trust versus fear
16:57 - Threat versus challenge appraisal
19:20 - Why modern life breaks your biology
23:24 - Structuring travel around sleep
26:16 - Circadian amplitude and contrast
28:00 - Amplitude and menopause symptoms
30:17 - What heart rate variability means
32:34 - Biggest levers for perimenopause
37:04 - Light dose and exercise snacks
40:18 - Why fit people sleep less
44:34 - Cycle syncing and training
51:56 - Meal timing and late-night eating
55:55 - Sleep-wake consistency and aging
59:43 - Exercise timing and pregnancy
01:04:54 - Why behavior precedes thought
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 25 Aug 2026 - 1h 12min - 230 - The Gut Yeast That Brews Ethanol From Every Carb You Eat
Blowing four times the legal limit on a breathalyzer usually means one thing, but in 2015, a judge dismissed a DWI because the driver's own gut was fermenting alcohol from an ordinary carb-heavy dinner. It's called auto-brewery syndrome, and the fuel it runs on is the same load your muscle is supposed to be clearing from your blood.
In this solo episode, Dr. Gabrielle Lyon discusses:
How gut yeast overgrowth turns everyday carbs like pasta, bread, and rice into ethanol that registers as real intoxication, brain fog, dizziness, and allThe specific risk factors that open the door: dysbiosis, SIFO, repeated antibiotic use, and poorly controlled diabetes or fatty liverThe three-part protocol to correct it, reduce the yeast burden, remove the carbohydrate fuel, and rebuild the microbiome, plus the carbohydrate challenge test, most doctors never runWhy skeletal muscle is your body's primary site for clearing blood sugar, and how an under-muscled body drifts into the same insulin-resistant, dysbiotic state that lets fermentation take holdWhether or not you'll ever face this rare diagnosis, you'll walk away understanding that gut health and muscle health share one supply chain and that defending your muscle is how you starve the problem at its root.
Study & References:
Woman beats DWI — her body brews alcohol (CBS News, 2015): https://www.cbsnews.com/news/woman-beats-dwi-with-rare-defense-her-body-brews-alcohol/
Cordell & McCarthy (2013), Int. J. Clin. Med. — foundational U.S. case study: https://doi.org/10.4236/ijcm.2013.47054
Malik, Wickremesinghe & Saverimuttu (2019), BMJ Open Gastroenterology: https://doi.org/10.1136/bmjgast-2019-000325
Painter, Cordell & Sticco — Auto-Brewery Syndrome, StatPearls (NIH): https://www.ncbi.nlm.nih.gov/books/NBK513346/
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Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
01:06 - The 2015 DUI dismissed in court
01:39 - Auto brewery syndrome defined
03:10 - The 2013 brewer's yeast case
03:46 - Why the evidence is thin
04:37 - How gut yeast ferments carbs
06:45 - Five conditions that trigger it
07:21 - SIFO vs SIBO explained
08:12 - Antibiotics and metabolic disease
10:00 - The carbohydrate challenge test
11:07 - Three non-negotiable treatments
12:53 - Muscle: the metabolic sink
15:07 - The under-muscled phenotype
17:03 - Your four directives
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 20 Aug 2026 - 20min - 229 - The 1 Macronutrient High Performers Skip After 60 | Arthur Brooks, PhD
Most people chase happiness as a feeling and wait for certainty before making big decisions, and both instincts quietly backfire. Dr. Arthur Brooks joins Dr. Gabrielle Lyon to break down what happiness is and how to act on it.
In this episode, Dr. Gabrielle Lyon and Dr. Arthur Brooks discuss:
The three "macronutrients" of happiness - enjoyment, satisfaction, and meaning, and why pursuing pleasure alone leads to detox, not happinessA usable rule for any hard decision: aim for roughly 80% excitement, 20% fear, and near-zero "deadness" once you have about 80% situational awarenessWhy solo pleasures don't stick if you're doing it alone, you're probably doing it wrong, and how enjoyment requires people plus memoryHow GLP-1s, SSRIs, and hormonal shifts can dull motivation, reward, and desire, and why knowing this gives you power over itSimple tech protocols: phone-free first hour, meals, and last hour that protect oxytocin, meaning, and connectionUnderstand happiness as something you build rather than something you wait to feel, and you walk away with concrete tools to decide better, connect deeper, and stop mistaking achievement for love.
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Listen to “Office Hours” on all your favorite platforms!
YouTube: https://www.youtube.com/playlist?list=PLDksUNNE9g_ZC6YJ3eG9lhZrMOG6IVuGR
Apple Podcasts: https://podcasts.apple.com/no/podcast/office-hours-with-arthur-brooks/id1832119842
Spotify: https://open.spotify.com/show/3fT0FLFsPgV2mbVjuOo3JV?si=e4d69f6725194d48
Get Dr. Arthur Brooks’ books here: https://www.arthurbrooks.com/books
📱Connect with Arthur Brooks:
Website: https://www.arthurbrooks.com/
YouTube: https://www.youtube.com/@drarthurbrooks
Instagram: https://www.instagram.com/arthurcbrooks/
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LinkedIn: https://www.linkedin.com/in/arthur-c-brooks/
🙌Thank you to our sponsors:
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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Spotify: https://bit.ly/4cWTbLG
📱Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
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LinkedIn: https://bit.ly/3N1nrdL
Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 - Intro of show
02:14 - Enjoyment, satisfaction, and meaning
02:55 - Pleasure vs enjoyment
05:04 - Why strivers can't enjoy life
07:05 - The four affect profiles
13:46 - Meaning: the protein of happiness
14:26 - Satisfaction and struggle
18:10 - Suffering equals pain times resistance
23:57 - The mistakes that sabotage happiness
28:12 - How to make hard decisions
30:00 - Excitement, fear, and deadness
33:39 - GLP-1s, motivation, and desire
36:08 - SSRIs, birth control, and attraction
38:00 - The meaning crisis and screens
41:25 - Boredom and the shock experiment
43:07 - Tech-free protocols
49:50 - Transcendence and daily practice
56:35 - The striver's lament
57:44 - Why love can't be earned
1:02:42 - Falling in love, and staying in love
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 18 Aug 2026 - 1h 08min - 228 - Why You're So Bloated on Ozempic
You might think the number dropping on the scale is the whole win, but on a GLP-1, a meaningful share of what you're losing may be muscle, not fat, and the fiber that's supposed to help can quietly make things worse.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why 25–40% of the weight lost on GLP-1 medications can be lean mass, and how to protect your muscle with adequate protein (1.2–1.5 g/kg) and resistance trainingThe GLP-1 fiber paradox and why these drugs need fiber to work, but make it hard to tolerate, and why 40–70% of patients hit GI side effects like bloating and constipationWhen to fiber max vs. fiber mine, plus how to reintroduce fiber gradually so you get the gut benefits without the bloat, bezoars, or obstruction riskGet this balance right, and you keep your muscle, calm your gut, and let the medication do its job instead of ending up bloated, constipated, and quietly losing strength.
Thank you to our sponsors:
Square - Get up to $200 off Square hardware when you sign up at square.com/go/drlyonBodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/3TJVSsv Upgrade your kitchen with Our Place today. Visit https://bit.ly/4q3ggRp and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4q3ZYb4 with the code DRLYON.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
00:46 - The pear bezoar and bowel obstruction
02:07 - Why 95% of Americans fall short
03:32 - The GLP-1 fiber paradox
04:18 - Why GLP-1 drugs make fiber hard to eat
05:50 - How GLP-1s slow the gut
07:40 - Bezoars, psyllium, and the 87-case series
09:12 - Fiber as therapy: titrating it right
10:03 - The muscle loss problem
11:28 - Getting the fiber and GLP-1 balance right
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 13 Aug 2026 - 14min - 227 - Taryn Smith - The Crash Nobody Warns You About After a Huge Win
You'd think fear is what stops you from doing hard things. At 25, with zero rowing experience, Taryn Smith crossed the Atlantic alone. 3,000 miles, 46 days, and I learned that the fear was never the obstacle. It was the signal she was finally in the right place.
In this episode, Dr. Gabrielle Lyon and Taryn Smith discuss:
Why fear is a "metric of success," not a stop sign, and how to train yourself to move toward discomfort instead of away from itHow food becomes visible performance fuel when you're the only engine, and how to preserve muscle on limited calories using protein and daily amino acidsThe "long-term optimist, short-term realist" mindset that carries you through a slog with no end in sightThe post-achievement crash nobody warns you about, and why the low after a big win is predictableWhether or not you'll ever touch an oar, you'll walk away with a portable mental framework for facing anything you've been avoiding, and a clearer sense of who you are when no one's watching.
Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSRe
📱Connect with Taryn Smith:
Website: https://www.tarynsmithmovement.com/
Instagram: https://www.instagram.com/tarynsmithmovement/
🙌Thank you to our sponsors:
Square - Get up to $200 off Square hardware when you sign up at square.com/go/drlyon
BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/3TJVSsv
Upgrade your kitchen with Our Place today. Visit https://bit.ly/4q3ggRp and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.
Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4q3ZYb4 with the code DRLYON.
📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
📱Connect with Dr. Gabrielle Lyon:
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TikTok: https://bit.ly/3OFK3kJ
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Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 - Intro of show
02:44 - From landlocked Nebraska to the ocean
03:37 - Chasing discomfort and stacking bigger adventures
05:17 - Fear as the real metric of success
08:57 - The unglamorous first steps of training
10:51 - College, family, and why criminal defense
14:06 - Trusting the instinct and the "calling"
16:00 - Impermanence, grief, and losing her grandfather
19:08 - 46 days, the weather, and the daily slog
21:05 - Training the body: ERG, lifting, injury prevention
30:11 - Solitude and the voice in your own head
31:12 - Food as fuel: eating to power the boat
36:08 - Supplements, aminos, and protecting muscle
38:37 - The storm that almost capsized the boat
43:17 - Sharks, marlin, and the real ocean dangers
46:36 - Music, dolphins, and the bird named Jo
52:11 - Long-term optimist, short-term realist
59:41 - The question no one asks her
1:00:50 - Five beautiful things: a journaling reframe
1:11:17 - The post-row crash nobody warns you about
1:19:02 - Recovery, appetite, and relearning hunger cues
1:24:02 - Training now: flexibility over rigid discipline
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 11 Aug 2026 - 1h 30min - 226 - What Glyphosate Does to Your Body
You've probably worried that the glyphosate on your bread is slowly harming you. The evidence points somewhere far less obvious and far more fixable.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why the real concern isn't cancer risk from your toast, but glyphosate's effect on your gut, where it can act like a selective antibiotic, hitting beneficial bacteria while sparing the harmful onesWhere the residue concentrates (grains and legumes like oats up to 1100 ppb) and why meat, milk, and eggs carry negligible amounts, so your organic dollars belong on oats and bread, not chickenThe three NHANES analyses linking higher glyphosate to weaker grip strength and greater sarcopenia risk, and why protein and resistance training matter more than agonizing over parts per billionHow switching to organic staples cuts urinary glyphosate by 71% in six days, and why "detox" products aren't the answerWhy banning glyphosate isn't a clean win, the leading alternative, 2,4-D, was a component of Agent OrangeUnderstanding where glyphosate genuinely matters lets you stop worrying about the wrong foods, spend smarter at the grocery store, and protect the two things that move the needle: your gut and your muscle.
Thank you to our sponsors:
Manukora - Go to https://bit.ly/4h6XYMQ to save 31% plus $25 worth of free gifts.Timeline - up to 20% off when you subscribe and save at https://bit.ly/3S2zg64Egglife - Find egglife wraps chillin’ in the fridge at Aldi, Whole Foods, Kroger, Target, Walmart & more. Visit https://bit.ly/3U5u55R to find a retailer near youExplore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: the glyphosate question
01:15 - Is my bread killing me?
03:15 - What glyphosate is and why we spray it
05:00 - Why 82% of us test positive
05:45 - Carcinogen or not: IARC vs EPA
06:45 - Hazard vs risk and the shark
08:15 - Pure glyphosate vs Roundup
09:45 - Your gut bacteria as the target
11:00 - The fecal transplant experiment
12:00 - Glyphosate and muscle loss
13:30 - Where the residue hides
15:30 - The GMO and Agent Orange problem
17:15 - The protocol: organic swaps, gut, muscle
18:24 - Key takeaways
19:10 - The answer for my patient
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 06 Aug 2026 - 20min - 225 - Juliet and Dr. Kelly Starrett - Your Back Pain Isn't Your Back
Most people think low back pain means something is wrong with their back. It's usually the hips — and the fix often starts on your living room floor.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Kelly Starrett and Juliet Starrett, JD to discuss:
Why 100% of the people who fly across the country to get a consult for stubborn low back pain are missing hip extension, and how to test yours with the couch stretchThe "injury vs. incident" framework that tells you when pain needs a doctor and when you can manage it yourselfHow 20–30 minutes of floor sitting each evening restores the range of motion you thought you'd lost to ageWhy mobility is the missing third leg of the longevity triangle that roughly 90% of people skipBy the end, you'll have a simple, no-equipment way to move without pain and keep the strength and mobility that let you do what you love as you age.
Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSRe
Listen to “The Ready State Podcast” on all your favorite platforms!
YouTube: https://youtube.com/playlist?list=PLB67wXqPqtMe7CcPnz12-_Ds4PRl2fiSZ&si=H4mVbg_kZbe7mszf
Apple Podcasts: https://podcasts.apple.com/us/podcast/the-ready-state-podcast/id1334232884
Spotify: https://open.spotify.com/show/53ma83Tknipc7b3ost1RNb
📱Connect with The Ready State:
Website: https://thereadystate.com/
YouTube: https://www.youtube.com/@TheReadyState
Instagram: https://www.instagram.com/thereadystate/
TikTok: https://www.tiktok.com/@the_readystate
Facebook: https://www.facebook.com/thereadystate
X.com: https://x.com/thereadystate
🙌Thank you to our sponsors:
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
📱Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
TikTok: https://bit.ly/3OFK3kJ
X.com: https://bit.ly/4l3YlaX
Facebook: https://bit.ly/3MBrJso
LinkedIn: https://bit.ly/3N1nrdL
Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 - Intro of show
02:33 - From performance to healthy aging
05:22 - Movement as an exercise prescription
08:21 - The movements the body should do
09:21 - Why walking isn't optional
11:07 - The gym as a movement language
14:04 - Range of motion as a pain generator
17:02 - The longevity triangle
22:19 - Why athletic people all have pain
23:12 - Injury vs. incident
25:34 - Pain is a request for change
30:22 - Humanity's lost hip extension
38:02 - Floor sitting: where to start
42:54 - Soft tissue work and foam rolling
48:20 - The couch test explained
53:24 - Why pickleball injures untrained bodies
55:11 - The ten movement vital signs
59:15 - Mobility vs. flexibility
1:00:04 - Mobility and muscle mass
1:04:34 - What kids lose in first grade
1:10:58 - The walking school bus
1:13:05 - Non-negotiables: pull-ups and shape
1:22:29 - Play as your warm-up
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 04 Aug 2026 - 1h 30min - 224 - DON'T Inject What You Can't Verify: Compounded Peptide Safety Explained
Over 500 published papers stand behind one of the internet's most popular peptides, but fewer than 30 of the humans studied are in them. Dr. Gabrielle Lyon separates the molecule from the marketplace so you can tell real evidence from good marketing.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why BPC-157's "mountain of evidence" collapses to a 99.7% animal-to-human ratio - 544 papers, but fewer than 30 humans across three uncontrolled pilot trialsHow to place any peptide on the spectrum from FDA-approved (GLP-1s like semaglutide) to investigational to compounded, and why "GLP-1s work, so peptides work" is a trapWhat the FDA quietly did in April 2026, and why removing a dozen peptides from its safety-concern list was driven by policy pressure, not new safety dataThe 4 questions to run on any peptide before you inject level of evidence, what the study measured, where it's sourced from, and whether it's banned in tested sportWhy the "boring work", resistance training, protein-anchored nutrition, and real recovery beat almost anything in a vialIf something is going into your body through a needle, the standard has to be higher than three words on a label that say "research use only." This episode gives you the framework to protect yourself before spending a dollar or taking a shot.
Thank you to our sponsors:
Head to https://bit.ly/4ftfObn and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4vZs75j OneSkin - Get 15% off at https://bit.ly/44XXQYy with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
01:30 - What a peptide is
03:40 - The first mistake: treating peptides as one category
05:50 - GLP-1s and the "peptides work" fallacy
09:30 - FDA-approved peptides: tesamorelin and s
15:40 - Repair peptides: BPC-157 and the Wolverine stack
16:30 - 544 studies, 30 humans: the evidence gap
20:00 - The strongest case for peptides
25:30 - The strongest case against peptides
29:00 - Compounded peptides and contamination risk
30:00 - What the FDA quietly did in April 2026
33:40 - The 4 questions to ask before any peptide
37:40 - The boring work that changes your life
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 30 Jul 2026 - 24min - 223 - 5 Hidden Causes of Bone Loss (#4 Is a Shock) - Dr. Douglas Lucas
Everyone on a GLP-1 is watching the scale; almost no one is watching their bones. Bone loss isn't an inevitable part of aging; it's a reversible signal that something deeper is going wrong, and it starts far earlier than most people are ever warned.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Douglas Lucas, a former Stanford-trained orthopedic surgeon turned bone-health specialist, to discuss:
Why bone loss begins around 45 during perimenopause, not 50, and why waiting for your first DEXA scan at 65 is far too late to prevent itThe blind spots in the standard DEXA scan: a scan-to-scan margin of error near 6% and no read on bone quality, only quantityBone turnover markers (CTX and P1NP) you can test from blood to see whether you're building or breaking down bone in real timeWhy the "protein is bad for bones" and "alkalize your diet" beliefs are myths and why protein, minerals, and adequate calcium matter more than calcium aloneWhat rebuilds bone at home: resistance training, real impact like heel drops, and vertical vibration plates used ~10 minutes a dayUnderstanding your bones as a living, changeable organ system means you can catch loss early, measure it honestly, and reverse the trajectory, instead of accepting decline as your fate.
Thank you to our sponsors:
Head to https://bit.ly/4ftfObn and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4vZs75jOneSkin - Get 15% off at https://bit.ly/44XXQYy with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Doug Lucas at:
YouTube: https://www.youtube.com/@Dr_DougLucasWebsite: https://drdouglucas.com/Instagram: https://www.instagram.com/dr_douglucas/LinkedIn: https://www.linkedin.com/in/doug-lucas-b0243522/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: Why a Stanford surgeon quit
02:00 - The 3 a.m. case that changed everything
04:35 - Bone as a dynamic organ system
06:14 - When bone loss begins
08:20 - Rejecting age-related bone loss
09:27 - Why the conventional playbook fails
10:55 - The two classes of bone drugs
14:38 - Bone quantity vs. bone quality
17:23 - Best tests for bone quality
20:52 - T-score vs. Z-score explained
26:59 - Hormones directed at bone
27:08 - Bone turnover markers P1NP and CTX
34:57 - Bone loss starts at 45, not 50
39:23 - Calcium myths and what to eat
45:42 - How to destroy your bones
50:12 - Medications that weaken bone
54:46 - Why an ultra-runner still lost bone
55:53 - Heel drops and impact training
57:54 - Vibration plates and osteogenic loading
1:12:38 - Know your starting point
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 28 Jul 2026 - 1h 18min - 222 - The Hidden Meat Allergy Millions Don’t Know They Have
You've eaten red meat your whole life, so why does a steak dinner suddenly leave you covered in hives at 1 AM? A single Lone Star tick bite can rewire your immune system into a delayed allergy to red meat, and most people (and even their doctors) never connect the two.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why alpha-gal reactions are delayed 2–6 hours after eating meat, and how that delay causes ER visits to be repeatedly misdiagnosedHow your blood type changes your risk (type A and O are higher-risk; type B appears protected) and why a mismatched transfusion has proven fatalThe simple alpha-gal IgE blood test to ask for, and what the numbers meanThe hidden sources beyond food: gelatin, vaccines, heparin, thyroid meds, and even heart valvesThe tiered treatment approach that resolves symptoms in about 80% of patients on meat-avoidance aloneLearn to recognize a condition that's increasingly common yet widely missed, so if it's happening to you, you'll know exactly what to test for and how to get your life back. It's not all in your head.
Thank you to our sponsors:
Cozy Earth - Go to https://bit.ly/3RLZNEv for up to 20% off!Timeline - Get 20% off your Mitopure order at https://bit.ly/4ptIchfSquare - Get up to $200 off Square hardware when you sign up athttps://bit.ly/4gOCfZP #squarepodExplore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
00:38 - How to spot the Lone Star tick
02:15 - Why this tick hunts you
03:40 - Where the tick is spreading now
05:10 - Diseases the Lone Star tick carries
06:30 - What alpha-gal syndrome is
08:45 - Why the reaction is delayed 2 to 6 hours
10:20 - Cofactors that make reactions worse
12:05 - Blood type and your risk level
14:30 - The transfusion danger nobody screens for
16:15 - The blood test and what the numbers mean
19:40 - Foods and hidden sources to avoid
23:10 - The three-tier treatment approach
27:00 - Hidden alpha-gal in meds, vaccines, and implants
31:20 - Preventing tick bites and getting tested
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 23 Jul 2026 - 24min - 221 - GLP-1's Dark Side No One Warns You. What Rapid Weight Loss Does to Your Face and Skin - Dr. Kristy Hamilton
Everyone celebrates the weight GLP-1s take off, almost no one warns you about the volume they quietly pull out of your face and the loose skin you can't train away. The fix depends entirely on the diagnosis, and knowing which category your concern falls into is what saves you time, money, and regret.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Kristy Hamilton, a board-certified plastic surgeon, to discuss:
Why rapid GLP-1 weight loss deflates facial volume and creates loose skin and why the leaner and more muscular you get, the more visible that laxity becomesThe muscle-sparing breast augmentation (Preserve) that gets active women back to full training in about a week, and why placing an implant in front of the muscle protects your strengthWhich skin-tightening treatments reset structure (like internal radiofrequency) versus the surface treatments and "expensive coat rack" machines that won't touch real laxityThe real NIH data on breast implant illness and why you don't need a $30,000 detox or to have healthy tissue cut out to get reliefBy the end, you'll know what rapid weight loss really does to your skin, which procedures match which problem, and how to avoid wasting money on fixes that were never going to work for your specific situation.
Thank you to our sponsors:
Cozy Earth - Go to https://bit.ly/3RLZNEv for up to 20% off!Timeline - Get 20% off your Mitopure order at https://bit.ly/4ptIchfSquare - Get up to $200 off Square hardware when you sign up athttps://bit.ly/4gOCfZP #squarepodExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Kristy Hamilton at:
Website: https://www.drkristyhamilton.com/Instagram: https://www.instagram.com/drkristyhamilton/Facebook: https://www.facebook.com/drkristyhamilton/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: GLP-1s and the plastic surgery boom
01:53 - The dark side: losing facial volume
02:40 - Fat transfers and donor-fat products
03:10 - Alloclae and the "zombie" fat
06:04 - The Miami Thong Lift explained
11:15 - Thong lift vs. BBL recovery
13:05 - Pec muscle-sparing breast augmentation
15:30 - Behind vs. in front of the muscle
20:43 - Silicone vs. saline implants
21:39 - Breast implant illness and the NIH data
24:16 - Predatory explants and the $30K program
31:33 - Implant size and the ballerina breast
37:00 - Non-surgical tightening with Quantum RF
41:00 - Are you a candidate? The pinch test
46:43 - Why surface treatments miss the structure
1:00:12 - Collagen banking for aging skin
1:03:01 - A new non-opioid pain drug
1:15:24 - Why fit women still fight loose skin
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 21 Jul 2026 - 1h 18min - 220 - Is Your Protein Aging You? What the Longevity Science Gets Wrong
The longevity world has convinced a generation of women that protein is shortening their lives. The science says they've got it backwards and the people hurt most are the ones who need protein most.
In this episode, Dr. Gabrielle Lyon breaks down the protein-and-longevity fear, steelmans the strongest case against protein, then walks through what the evidence shows:
The RDA (0.8 g/kg) is a deficiency floor, not a target, the intake one camp calls "dangerously high" is what federal guidelines and expert groups now recommend (1.2–1.6 g/kg)The IGF-1–cancer link is tiny (a 3–11% risk bump vs. smoking's 1,000–2,000%), and the IGF-1–mortality curve is U-shaped: the lowest levels carry ~40% higher death riskSarcopenia roughly doubles death risk (3.5× with frailty) and perimenopause stacks anabolic resistance on top, exactly when women are told to fear the foods that defend themBy the end, you'll understand the mTOR and IGF-1 science well enough that nobody online can scare you off your own dinner, plus a simple Monday-morning plan: adequate protein, front-loaded, built on minimally processed foods, with heavy lifting to match.
Thank you to our sponsors:
BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4f7ZqM5 Our Place - Upgrade your kitchen with Our Place today. Visit https://bit.ly/4vT4cEr and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Lucy Get 20% off your next order with code DRLYON at https://lucy.co/, or find yours in store at https://bit.ly/4ybQCxHExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: Is Protein Really Shortening Your Life?
02:30 - Who the Protein Fear Hurts Most
03:29 - What mTOR Is (Two Complexes)
07:29 - The RDA Deception: High vs Low Protein
12:00 - The Falcone Reanalysis of Levine 2014
16:00 - The Strongest Case Against Protein
21:00 - Why Rodent Data Isn't Human Data
26:08 - The IGF-1 Cancer Story, Link by Link
29:00 - The U-Shaped Mortality Curve
32:00 - Insulin, Carbs, and Active IGF-1
34:30 - Sarcopenia, Frailty, and Death Risk
35:55 - Perimenopause and Anabolic Resistance
38:00 - Red Meat, TMAO, and Plant Protein Myths
39:51 - The Honest Verdict: Processed Meat
44:00 - How Much Protein and Your Monday Plan
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 16 Jul 2026 - 33min - 219 - Dr. Peter Hotez - 1 in 20 Americans Has This Parasite and Doesn't Know It!
The parasites most Americans think of as a tropical problem are already here; showing up as fatigue, asthma, and gut issues that standard tests keep calling "normal." An estimated 1 in 20 people may carry one and never know it.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Peter Hotez, a tropical-medicine physician and vaccine scientist, to discuss:
Why toxocariasis, a worm shed by household dogs and cats, may affect 5–6% of the U.S. population, with larvae migrating through the lungs and brainWhy standard PCR panels come back negative and which specific tests (antibody, fecal, eosinophil count) to ask forHow to lower your risk at home, from deworming pets on a vet schedule to knowing which symptoms warrant a targeted testWhy the popular "worm therapy for autoimmune disease" idea has the relationship backwards, worms are a leading driver of IBD and asthma, not a cureWhether you've been told your labs are fine but still feel off, this conversation gives you a clear, evidence-based framework for what to test for and how to protect your family from infections hiding in plain sight.
Thank you to our sponsors:
BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4f7ZqM5Our Place - Upgrade your kitchen with Our Place today. Visit https://bit.ly/4vT4cEr and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4yNdfJ7 with the code DRLYON.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Peter Hotez at:
Website: https://peterhotez.org/Instagram: https://www.instagram.com/peterhotez/Book - “Science Under Siege: How to Fight the Five Most Powerful Forces that Threaten Our World” - https://a.co/d/07P0iANSConnect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction: trust in science and nutrition
04:11 - Anti-parasitic drugs sold as snake oil
06:43 - How misinformation gets weaponized
18:23 - The turbo cancer claim debunked
24:41 - Finding experts you can trust
30:52 - Hepatitis B vaccine and how babies get infected
31:56 - The 75 vaccine myth: eight diseases to seventeen
35:42 - Why the COVID vaccine wasn't rushed
40:18 - Toxocariasis: the worm in stray dogs and cats
43:50 - Why parasite tests come back negative
45:57 - Hookworm in rural Alabama
48:05 - Eosinophils and how to test
50:21 - Worm therapy for autoimmune is backwards
54:19 - Deworming pets and family transmission
57:19 - Liver fluke and bile duct cancer
1:01:11 - Climate change and parasites in the US
1:03:16 - Lyme, ticks, and genomic surveillance
1:08:00 - Flu and COVID as cardiovascular threats
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 14 Jul 2026 - 45min - 218 - The Truth About Microplastics No One Is Telling You
You might think microplastics are just an environmental nuisance that passes through your body, but the latest tissue studies tell a very different story. As a physician, Dr. Gabrielle Lyon breaks down where the science lands, past both the fear-mongering and the dismissiveness.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why over 58% of patients in a landmark NEJM study had plastic embedded in their arterial plaque and the 4.5x higher risk of heart attack, stroke, and death that came with itHow microplastics act as a "Trojan horse," carrying endocrine-disrupting chemicals into your blood, testes, brain, and reproductive tissueWhy perimenopause and menopause are an especially vulnerable window for plastic-driven hormone disruptionThe five low-cost "Lyon Protocol" rules to cut your exposure, starting with never microwaving plastic and letting food cool before you store itThis matters because you don't need to overhaul your life or wait twenty years for perfect data to protect your cellular health; you just need the handful of small, automated decisions that move the needle on your metabolic and hormonal baseline.
Thank you to our sponsors:
Our Place - Upgrade your kitchen with Our Place today. Visit https://bit.ly/3RnCYH0 and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Timeline - Get 20% off your Mitopure order at https://bit.ly/4wJpFzZ Bon Charge - Save 15% at https://bit.ly/44bIoYx with code DRLYONExplore More from Dr. Gabrielle Lyon
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
01:30 - What microplastics and nanoplastics are
03:00 - Where plastics show up inside us
04:30 - The UCSF systematic review
06:10 - Inflammation, cytokines, and thyroid
07:40 - Plastic in arterial plaque and the 4.5x risk
10:10 - The strongest skeptic arguments
13:00 - Lead, asbestos, and trans fats
14:40 - The Trojan horse for hormone disruptors
16:10 - Reproductive aging and menopause
17:50 - Where Dr. Lyon lands
19:40 - The Lyon protocol: five rules
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 09 Jul 2026 - 23min - 217 - Cardio vs Strength Is a Myth and the Science Proves It - Dr. Alyssa Olenick
You've been told that 10,000 steps a day is enough to keep you healthy but when it comes to your bones and your muscles, walking falls short, and the science explains exactly why. The real drivers of strength, bone density, and lasting health are load, intensity, and resistance, not just movement.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Alyssa Olenick, a PhD in exercise metabolism and ultramarathoner who blends endurance and strength training, to discuss:
Why the "interference effect," the fear that cardio cancels your strength gains, is overblown for almost everyone, and what causes the carryover fatigueHow most women train too lightly, believing they're at a 9 out of 10 when they're closer to a 5, and never trigger real muscle adaptationWhy estrogen is not the primary driver of muscle, resistance training is, and what that means through the menopause transitionThe early warning signs of low energy availability, including cycle changes that show up long before a missed period, and the rapid bone loss that followsHow to structure strength, power, and cardio together, and fuel it properly without sabotaging recoveryYou'll walk away knowing how to train for strength, power, and bone density that lasts and why being undertrained, not fragile, is the real problem for most women.
The July Forever Strong Foundations Challenge begins July 6, 2026. This 4-week challenge is designed to help you build a stronger, more energized you through sustainable nutrition, training, and lifestyle habits. Register here: https://bit.ly/4p3DW7U
Thank you to our sponsors:
Our Place - Upgrade your kitchen with Our Place today. Visit https://bit.ly/3RnCYH0 and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Timeline - Get 20% off your Mitopure order at https://bit.ly/4wJpFzZBon Charge - Save 15% at https://bit.ly/44bIoYx with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Alyssa Olenick at:
Website: https://doclyssfitness.com/Instagram: https://www.instagram.com/doclyssfitness/The Running Ebook: https://doclyssfitness.com/running/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
02:09 - Hybrid vs. concurrent training defined
05:03 - Where beginners should start
10:12 - Movement vs. exercise vs. training
11:30 - The interference effect: the boogeyman
16:55 - Nervous system fatigue and bar speed
20:07 - Why running fatigues you more than cycling
26:04 - Fuel use, fat oxidation, and the crossover
34:39 - Mitochondria and metabolic flexibility
39:13 - What we don't know about women's physiology
44:18 - Type one vs. type two muscle fibers
46:00 - Testosterone, training age, and muscle gain
48:02 - What we confidently know about women and muscle
49:43 - Estrogen is not the muscle driver
53:14 - Menstrual cycle, performance, and perception
58:03 - Training the mind, not just the body
1:02:18 - The aerobic guidelines and doing more
1:06:26 - The 2026 resistance training guidelines
1:16:49 - Squat, hinge, push, pull explained
1:22:04 - Why walking isn't enough for bone
1:26:14 - Power, plyometrics, and power-penia
1:35:33 - Programming cardio without killing gains
1:41:03 - Low energy availability and warning signs
1:47:38 - Protein and carbs for the hybrid athlete
1:53:52 - The seasons approach: spend a year lifting
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 07 Jul 2026 - 2h 03min - 216 - The Testosterone Myth Men Have Been Lied To About
You were told your testosterone is "normal" so why do you still feel exhausted, weak, and off? The number on your lab report was never built for you, and your own genetics may be the reason it doesn't match how you feel.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why the standard 300–1000 ng/dL range ignores your age, comorbidities, and genetics, and why two men with identical labs can feel completely differentHow CAG repeats determine whether your body "catches" the testosterone you produce, meaning you might need 400 to feel great while someone else needs 800Why the 80-year-old fear that testosterone fuels prostate cancer is built on a single flawed 1941 study, and what the androgen saturation model proves insteadHow everyday endocrine disruptors BPA in receipts, phthalates in personal care, atrazine in tap water quietly lower your testosterone even when you eat clean and train hardThe correct AUA testing protocol your doctor may be skipping: two early-morning, fasted measurements plus actual symptoms, not one afternoon blood drawUnderstanding how your own body uses testosterone lets you walk into your doctor's office armed with facts instead of frustration and stop being told you're "fine" when you don't feel it.
Thank you to our sponsors:
OneSkin - Get 15% off at https://bit.ly/4ekX9gt with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
00:55 - Why one reference range fails everyone
01:45 - Men with normal labs who feel terrible
02:40 - Dismantling the prostate cancer myth ahead
03:40 - Testosterone decline by age data
04:30 - It's comorbidities and environment, not just age
05:10 - Endocrine disruptors and how they work
06:30 - How EDCs lower testosterone
08:00 - Common offenders and where they hide
09:00 - Receipts, atrazine, and performance apparel
10:30 - Reducing your chemical exposure
11:45 - The prostate cancer paradigm shift
12:20 - The flawed 1941 study
13:00 - The androgen saturation model
14:00 - Testosterone therapy with prostate cancer data
15:00 - What happens when you block androgens
15:45 - Androgens and brain protection
16:45 - CAG repeats and genetic variability
18:30 - The rain and buckets analogy
19:30 - AUA testing and diagnosis protocol
21:00 - Symptoms, targets, and safe monitoring
22:15 - Muscle-centric application and recap
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 02 Jul 2026 - 25min - 215 - Is the Protein RDA Too Low for You? What 40 Years of Studies Show - Dr. Don Layman & Dr. Heather Leidy | GLS #214
The July Forever Strong Foundations Challenge begins July 6, 2026. This 4-week challenge is designed to help you build a stronger, more energized you through sustainable nutrition, training, and lifestyle habits. Register here: https://bit.ly/4gCmoNR
For 40 years you've been told 0.8 grams of protein per kilogram is "enough" but the scientists who contributed the reports behind the new 2025–2030 Dietary Guidelines say not a single study has ever shown that number beats eating more.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Don Layman and Dr. Heather Leidy, the protein researchers who developed the scientific reports informing the new U.S. Dietary Guidelines, to discuss:
Why the guidelines reprioritized protein to a healthy range of 1.2–1.6 g/kg and why that still isn't technically "high protein"
Why you don't really have a protein requirement, but an essential amino acid requirement and what that means for your brain, mood, and antioxidant production
Who's quietly falling short: roughly 20% of women over 60 sit below the RDA, and adolescent girls are among the most consistently deficient
How to spot real protein on a label (Layman's 10-gram threshold) and why most "+protein" snacks are just fairy dust
What a higher-protein breakfast does to afternoon cravings, backed by fMRI brain-reward data
Walk away knowing how much protein you actually need, why "enough to avoid deficiency" and "enough to thrive" are two different numbers, and how to build every meal around protein first so you're covered on the nutrients that matter most.
Thank you to our sponsors:
OneSkin - Get 15% off at https://bit.ly/4ekX9gt with code DRLYON
Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.com
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Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/
Find Dr. Donald K. Layman at:
Website: https://www.metabolictransformation.com/
Instagram: https://www.instagram.com/layman.don
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/
TikTok: @drgabriellelyon
X (Twitter): https://x.com/drgabriellelyon
Facebook: https://www.facebook.com/doctorgabriellelyon
Chapters
00:00 - Introduction
02:00 - The biggest change in 45 years
03:36 - Why the guidelines are so controversial
06:09 - Process complaints vs. the science
08:25 - Protein was always there, just hidden
10:26 - Is 1.6g really high protein?
13:00 - Half of people are below average
13:45 - The randomized trials that say no benefit
16:57 - Why cherry-picked studies mislead
18:42 - Amino acids are essential, fiber isn't
21:17 - Does protein only matter with lifting?
33:33 - Nitrogen balance and its blind spot
40:02 - The carbohydrate RDA everyone ignores
47:37 - The nine essential amino acids
49:49 - Why aging makes deficiency worse
53:36 - Going below 50% animal protein
58:25 - Protein quality and carbohydrate dilution
1:04:34 - Hitting protein when you're small
1:08:53 - High-protein breakfast and the teen brain
1:10:19 - fMRI: blunted food cravings
1:18:40 - The saturated fat sticking point
1:26:30 - The 10% number from thin air
1:40:17 - Is protein in everything fairy dust?
1:46:42 - Smart high-protein snacks
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 30 Jun 2026 - 1h 56min - 214 - Nobody Tells You What GLP-1s Do to Your Sex Drive | GLS #213
The receptor that switches off your appetite on a GLP-1 drug is the same one wired into your reward circuitry, your hormones, and your blood vessels, which means when you turn down hunger, something else may be getting turned down too, and for most people taking these drugs, nobody ever checked.
In this solo episode, Dr. Gabrielle Lyon discusses:
Why the same drug class can improve sexual function in men with obesity while potentially dampening it in lean or postmenopausal women — and why the deciding factor isn't the drug, it's the bodyHow rapid weight loss raises SHBG, the protein that soaks up free testosterone, so a "normal" total testosterone result can hide a real deficit your bloodwork won't flagWhy women make up 60–70% of GLP-1 prescriptions yet the entire evidence base for female sexual function is two case reports, with zero validated questionnaires in any pivotal trialThe three-tier action plan for anyone on or about to start a GLP-1 — baseline your sexual function first, get free testosterone tested, and protect muscle with protein and resistance trainingWhether you're on a GLP-1 drug or considering one, you'll walk away knowing exactly what to measure before you start and what to watch for after — so a change in your sexual health gets caught as the vital sign it is, instead of being quietly dismissed.
Thank you to our sponsors:
Cozy Earth - Go to https://bit.ly/44qcXtu for up to 20% off! Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/3QEpYMX or find yours in store at https://bit.ly/3SGAEv3 .Kettle & Fire - Head to https://bit.ly/4oJokGu and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok:https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
01:30 - The 35-year-old patient case
04:00 - The question: harm or help?
05:00 - The case against: the 4.5x ED study
06:30 - FAERS database and 182 reports
08:00 - Reward circuits, blood flow, and SHBG
11:00 - Women are 70%, the data is two case reports
12:30 - The case for: detection bias explained
15:00 - Validated studies show testosterone rising
17:00 - GLP-1 vs testosterone therapy and fertility
19:00 - Same receptor, different body
22:00 - Cross-examination: holes in both sides
26:00 - Why the drugs may not all be the same
30:00 - Confidence levels: what Lyon actually believes
33:00 - Tier 1: baseline, hormones, protein, training
35:00 - Tier 2 and 3: dose, molecule switch, adjuncts
36:30 - Your sexuality is a vital sign
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Thu, 25 Jun 2026 - 37min - 213 - Why Strength Beats Cardio After 50: Muscle, Longevity & Bone Density - Lisa Smith-Batchen
You might think more cardio is the key to aging well but Lisa Smith-Batchen, who has run 135 miles through Death Valley ten times, says it's strength that actually carries you through the decades.
In this episode, Dr. Gabrielle Lyon sits down with Lisa Smith-Batchen, one of the most decorated ultra-endurance athletes in American history and a 10-time Badwater 135 finisher, to discuss:
Why being strong matters more than being fast and why "it's not the running that helps me run, it's being strong"The first movement everyone should train at any age: sit to stand, followed by squats, wall sits, lunges, and pushupsWhy cutting protein after 60 backfires, and why Lisa fuels on roughly 80% protein calories during racesHow to start lifting late, her 85-year-old client went from 5-pound weights to 230-pound farmer carriesThe fall that ended her father's life, and why "pick your feet up" became her mission for aging athletesYou'll walk away with a clear, muscle-first blueprint for staying strong, mobile, and independent for life — and the motivation to start today instead of waiting for another Monday.
Thank you to our sponsors:
Cozy Earth - Go to https://bit.ly/44qcXtu for up to 20% off!Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/3QEpYMX or find yours in store at https://bit.ly/3SGAEv3 .Kettle & Fire - Head to https://bit.ly/4oJokGu and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Lisa Smith-Batchen at:
Website: https://dreamchaserevents.com/Instagram: https://www.instagram.com/coachlisasmithbatchenFacebook: https://www.facebook.com/lisa.smithbatchenConnect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok:https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
02:10 - From marathon to the Badwater 135
05:31 - The first race and learning the hard way
06:41 - Inside the pain cave
13:46 - Why she went back ten times
16:51 - Bonking, hydration, and what changed
21:12 - Finding your why
28:04 - Running for something greater
33:25 - Strong over fast: the real secret
35:59 - The lifting myths men and women believe
44:13 - Where a beginner should start
47:02 - Sit to stand: the non-negotiable move
48:56 - The habit that killed her father
51:11 - Why falls are so devastating
54:14 - The danger of low-protein advice for older adults
59:00 - Stop waiting for Monday
01:01:37 - Fueling: protein, sodium, and calories per hour
01:13:01 - Why a DNF isn't failure
01:18:13 - Unfinished business and the right choice
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 23 Jun 2026 - 1h 23min - 212 - Laura Horvath, Chris Hinshaw & James Sprague: What Separates Champions From Everyone Else
What does it actually mean to win at the highest level? In this powerful compilation, I’m with 2024 CrossFit Games champion James Sprague, 2023 CrossFit Games champion Laura Horvath, and legendary endurance coach Chris Hinshaw to unpack the mental game behind elite performance, the vulnerability that follows victory, and why champions are often more fragile in the moments just after they win. What does winning mean to you right now?
Connect with James Sprague
Website: https://games.crossfit.com/athlete/900251
YouTube: https://youtube.com/@spraguerrrr?si=zTrH9d5valcjlq-t
Instagram: https://www.instagram.com/spraguerrrr/
Facebook: https://www.facebook.com/spraguerrrr/
Connect with Laura Horvath
Website: https://games.crossfit.com/athlete/591912
YouTube: https://youtube.com/@kaduzs23?si=3j8mXAnf38H7uGvi
Instagram: https://www.instagram.com/laurahorvaht/?hl=en
Facebook: https://www.facebook.com/laurhorvath/
TikTok: https://www.tiktok.com/@laurahorvaht
X: https://x.com/laurahorvaht
Connect with Chris Hinshaw
Website: https://www.aerobiccapacity.com/
Instagram: https://www.instagram.com/hinshaw363/
Facebook: https://www.facebook.com/hinshaw363/
Thank you to our sponsors:
Bodyhealth - Use the code “LYON20” to get 20% off your first order! https://bit.ly/4r2ImeF
Our Place - Use code “DRLYON” for 10% of sitewide. https://bit.ly/4r77SiU
Manukora - save 31% plus $25 worth of free gifts. https://bit.ly/4sglER1
Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/
TikTok: https://www.tiktok.com/@drgabriellelyon
X (Twitter): https://x.com/drgabriellelyon
Facebook: https://www.facebook.com/doctorgabriellelyon
Timestamps:
00:00 - Intro of Show
00:52 - The Rogue Invitational and qualifying
01:41 - Applying friction in elite training
02:27 - Why winners are vulnerable
02:47 - CrossFit and HYROX recovery demands
03:23 - Active versus passive rest
04:14 - Why records keep breaking
05:18 - Training by feel without wearables
06:16 - Mastering movement before intensity
07:21 - Reframing pain as growth
08:25 - How CrossFit events are structured
09:47 - Building structural integrity
10:38 - The three bases of the sport
11:34 - Getting comfortable being uncomfortable
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Thu, 18 Jun 2026 - 13min - 211 - What Your ED Is Really Telling You About Your Heart, Blood Sugar & Hormones - Urology Roundtable
Most men think erectile dysfunction is a bedroom problem and low testosterone is just a fact of getting older. This roundtable makes the case that both are early warning lights for your heart, your metabolism, and your long-term health and that ignoring them can cost you a decade.
In this episode, Dr. Gabrielle Lyon sits down with urologists and men's health specialists Dr. Mohit Khera, Dr. Larry Lipshultz, and Dr. Tobias Köhler to discuss:
Why a 35-year-old with ED carries a ~15% risk of heart attack or stroke within 7 years, ~3.5x the risk of depression, and ~30% odds of diabetes or prediabetes and why a prescription alone misses all of itWhy "age-related" testosterone decline is largely a misnomer: a healthy man shouldn't drop significantly with age, so falling T usually signals something reversible underneathHow testosterone became the single best blood marker of a man's overall health, and the case for annual screening that almost no man getsWhat the TRAVERSE trial changed when the FDA removed testosterone's cardiovascular warning in 2025, debunking the prostate-cancer and heart-attack fearsThe 2-minute monthly self-exam every man should do to catch testicular cancer early, when it's ~99% curableIf you've been told your symptoms are "just aging" or you love a man who refuses to see a doctor. This conversation shows you how to read the signals your body gives long before a crisis hits.
Thank you to our sponsors:
Body Health - Use the code LYON20 to get 20% off your first order https://bit.ly/4efgBuMTimeline - Get 20% off your Mitopure order at https://bit.ly/49LSbYzBranch Basics - Save 15% at https://bit.ly/4uuw4x3 with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Larry Lipshultz at:
Instagram: https://www.instagram.com/lipshultzmd?igsh=NTc4MTIwNjQ2YQ==Website: https://www.larrylipshultz.com/YouTube: https://www.youtube.com/@DrsAmyandLarryFind Dr. Tobias Kohler
Instagram: https://www.instagram.com/tobiaskohlermd?igsh=NTc4MTIwNjQ2YQ==X: https://x.com/sexhealthmd?s=11Find Dr. Mohit Khera
Instagram: https://www.instagram.com/drmohitkhera?igsh=NTc4MTIwNjQ2YQ%3D%3DX: https://x.com/DrMohitKheraWebsite: https://drmohitkhera.com/Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
01:30 - What doctors got wrong about testosterone
05:05 - The prostate cancer myth, debunked
07:12 - The best marker of a man's health
11:51 - Is age-related decline actually real?
14:15 - How obesity crushes testosterone
18:11 - Testosterone and reversing diabetes
20:06 - GLP-1 versus testosterone
25:20 - What "low testosterone" really means
29:05 - Dosing, CAG repeats, and microdosing
42:34 - The TRAVERSE trial and FDA reversal
47:10 - The prostate saturation point
56:49 - Peptides, explained
01:03:00 - Why ED is a check engine light
01:08:26 - The desert of men's health care
01:11:06 - The case for annual screening
01:16:45 - Varicoceles and male fertility
01:20:03 - How to check for testicular cancer
01:26:44 - Final advice for men
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 16 Jun 2026 - 1h 33min - 210 - How to Stay Calm in a Crisis and Why Detachment Is a Trainable Skill - Jamie Cochran
Your ego isn’t the enemy, but if you’re not actively controlling it, it is running your team, your home, and your most important relationships. Jamie Cochran, COO of Echelon Front, has spent 13 years helping leaders fix the root cause most of them never look for.
The Women’s Leadership Assembly live event runs January 5–7, 2027 in Palm Springs. A free monthly webinar series runs year-round. More details here:https://events.echelonfront.com/product/assembly-004/?utm_source=google&utm_medium=cpc&utm_campaign=22652941380&utm_content=&utm_term=&utm_source=google&utm_medium=paid&utm_campaign=22652941380&utm_content=&utm_term=&gadid=&gad_source=1&gad_campaignid=22662710098&gclid=CjwKCAjwxITRBhBYEiwA6mZm7VZs1jY-jUq1ugoigo8XEDkYsRsSEpOs2eblax5TQOW-9LT_K-hVhBoC1RkQAvD_BwE
Thank you to our sponsors:
Timeline - Get 20% off your Mitopure order at https://bit.ly/4dW6BGNBodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4uR4NWBUpgrade your kitchen with Our Place today. Visithttps://bit.ly/4dSD4Pz and use code DRLYON for 10% off sitewide.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Jamie Cochran at:
Website:https://echelonfront.com/
YouTube:https://youtube.com/@echelonfront?si=2x5aCudkXTvicfJO
Instagram:https://www.instagram.com/jamielynncochran/
Facebook:https://www.facebook.com/jamie.cochran.7/
LinkedIn:https://www.linkedin.com/in/jamie-lynn-cochran-5ab79013
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 Intro of Show
01:33 The Spartan Warrior Selection
02:25 Why Female Leadership Is Misunderstood
06:35 Are Leadership Tools Evolving or Constant?
07:12 What Is Extreme Ownership?
11:44 Owning It All vs. Doing It All
12:34 Female Leadership: Strength vs. Confidence vs. Aggression
17:57 Imposter Syndrome: Healthy or Dangerous?
23:37 Leadership Skills: Natural or Trainable?
31:00 Detachment from Emotion: On Making Better Decisions
32:32 Healthy Competition Against Women
36:20 Jamie’s Thyroid Cancer Diagnosis and Practicing Detachment
48:12 Avoidant Leaders and Default Aggressive Bias for Action
51:96 Top 3 Mistakes Leaders Make
52:43 The Leadership Capital Framework
57:54 The PIOS Framework: Problem, Impact, Ownership, Solution
1:00:10 When to End a Professional Relationship
1:04:29 The Women’s Leadership Assembly: Origin Story
1:07:05 Impact of Social Media on the Confidence of Young Girls
1:13:35 Compounding Habits that Improve Leadership over Time
1:14:55 Discipline as a Parenting Tool
1:22:07 Recognising when your Leadership Capacity is Failing
1:24:51 Women’s Assembly in January 2027: Palm Springs
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 09 Jun 2026 - 1h 26min - 209 - Penis Health, What Every Man Needs to Know - Dr. Amy Pearlman
Most men think erectile dysfunction is a bedroom problem. It's actually one of the earliest warning signs of cardiovascular disease, capable of showing up three to five years before a heart attack.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Amy Pearlman, a urologist trained in men's sexual health, to discuss:
Why ED is a symptom of vascular health, not a standalone disease and how the artery feeding the heart is roughly double the size of the one feeding the penis, so problems show up "down there" firstWhy "normal" testosterone can be meaningless, and the questions to ask before accepting a lab result that didn't flagHow daily erections preserve penile tissue the way water keeps a sponge supple and why disuse can cost noticeable size over just a few monthsThat cardiovascular exercise can rival ED medication for improving erectile function, making your heart health the real fixHow to track erectile fitness before there's a problem, instead of waiting until something breaksBy the end, you'll understand the single signal your body uses to flag heart and metabolic risk early and the simple, mostly drug-free steps that protect both your cardiovascular health and your sexual function for life.
Thank you to our sponsors:
Manukora - Go to https://bit.ly/3RCMrKx to save 31% plus $25 worth of free gifts.Timeline - Get 20% off your Mitopure order at https://bit.ly/4dW6BGNBon Charge - Save 15% at https://bit.ly/433Xi2B with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Listen to "Pearls of Wisdom" on all your favorite platforms!
Spotify: https://open.spotify.com/show/4uOhWn5DeVXO7D2ppa0RoV
Apple Podcasts: https://podcasts.apple.com/us/podcast/pearls-of-wisdom/id1617916659
Find Dr. Amy Pearlman at:
Website: https://www.primeinstitute.us/
YouTube: https://youtube.com/@docamyurology?si=oJ2LZ_sxMPYTaK41
Instagram: https://www.instagram.com/amypearlmanmd/
LinkedIn: https://www.linkedin.com/in/amy-pearlman-54a2b0208
Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonTimestamps
00:00 - Introduction
01:25 - Erections predict cardiac events
01:41 - The pen and artery analogy
03:40 - No health milestones for men
07:52 - Normal structure and function
11:45 - The five S's of men's health
21:24 - Why "normal" testosterone misleads
25:00 - Testosterone and fertility risk
31:05 - Steroids versus FDA-approved agents
41:13 - The untreated 25-year-old
43:56 - Sperm health and home testing
52:02 - Peyronie's disease and injury
1:01:34 - Protein, nutrition, supplements
1:05:09 - Daily Cialis as a pre-workout
1:13:32 - The sponge analogy
1:15:31 - Erectile fitness tracking
1:23:05 - The penis pump, used right
1:27:24 - Restoring lost size
1:35:00 - Traction and girth enhancement
1:46:00 - Women's anatomy and pleasure
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 02 Jun 2026 - 1h 52min - 208 - Your Doctor Is Watching the Wrong Number. LDL, ApoB & Heart Risk Explained. - Dr. Kevin Maki
Most people think the cholesterol number on their lab report tells them whether their heart is at risk. But former National Lipid Association President Dr. Kevin Maki explains that LDL is just one piece of a much bigger picture and focusing on it alone can mean missing the markers that matter most.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Kevin Maki, former President of the National Lipid Association and co-editor-in-chief of the Journal of Clinical Lipidology, to discuss:
Why ApoB and Lp(a) are better predictors of heart risk than LDL and why only about 2% of people ever get Lp(a) testedWhat a beef-vs-chicken feeding study revealed about red meat and cholesterol (the LDL results came back identical at 112 mg/dL)The evidence behind the seed oil debate, including why higher linoleic acid levels tracked with lower inflammation markers across a 2,000-person datasetWhy the balance of cholesterol-raising and cholesterol-lowering foods matters more than saturated fat aloneThe simple "ABCs" framework: A1c, blood pressure, cholesterol - for actually lowering long-term cardiovascular riskBy the end, you'll know which numbers actually predict heart risk, which tests to ask your doctor for, and how to cut through the conflicting noise around fat so you can make evidence-based decisions for the long haul.
Thank you to our sponsors:
OneSkin - Get 15% off at https://bit.ly/4tZnOpk with code DRLYONBodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/48SJ7AC Amp - Visit https://bit.ly/3RcmqBz to get your AI-powered at-home gym for smarter, personalized training.Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Kevin Maki at:
Midwest Biomedical Research:https://www.mbclinicalresearch.com/ LinkedIn:/ kevin-c-maki-phd-497ba34Connect with Dr. Gabrielle Lyon:
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 - Introduction
00:31 - Dr. Kevin Maki and the National Lipid Association
01:04 - New dietary guidelines and the LDL confusion
02:04 - What raises and lowers LDL cholesterol
03:51 - Cholesterol levels from birth through puberty
05:11 - The lipid panel kids should get before age 11
06:42 - Lp(a): the test only 2% of people get
08:18 - ApoB and the three risky particle types
11:35 - Do we have evidence for "lower is better"?
14:09 - The FLASH-GLICK risk factor framework
17:10 - The 10% saturated fat guideline explained
19:36 - Many dietary patterns can be healthy
24:50 - Beef vs. chicken: identical LDL results
27:10 - The balance of fatty acids that matters
29:24 - Olive oil vs. corn oil feeding study
31:00 - Lower for longer: 40-year risk reduction
34:15 - Genetic cholesterol disorders and risk
40:33 - The omega-3 index and why it matters
49:10 - Are seed oils really driving inflammation?
53:11 - How seed oils are processed and refined
1:07:48 - Inherited beliefs and outdated nutrition science
1:08:54 - Butter vs. cheese and high-fat dairy surprises
1:14:48 - Exercise effects on HDL and triglycerides
1:21:20 - The ABCs of reducing cardiovascular risk
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 26 May 2026 - 1h 25min - 207 - The Cancer Doctors Keep Missing in Young Adults - Dr. Michelle Pearlman
Colorectal cancer is now the leading cancer killer in adults under 50, and patients in their 20s are presenting with metastatic disease that has nothing to do with family history. Most physicians are still telling young patients with rectal bleeding that it's probably just hemorrhoids and that's costing lives.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Michelle Pearlman, a board-certified gastroenterologist and founder of a Miami-based gastro-metabolic clinic, to discuss:
The specific warning signs every adult under 50 should never ignore, regardless of age including rectal bleeding, unintentional weight loss, and persistent abdominal painWhy GLP-1 medications like Ozempic and Zepbound are being miscategorized as weight loss drugs when they're actually metabolic reprogrammers with applications in fatty liver, sleep apnea, and inflammationThe protein, fiber, and resistance training protocol Dr. Pearlman uses to protect muscle mass in patients on GLP-1 therapyHow hormone replacement therapy combined with GLP-1s is changing body composition outcomes for perimenopausal women and why current guidelines are still 20 years behind the dataDr. Pearlman's personal osteoporosis diagnosis at 39, despite being a lifelong bodybuilder, and what it revealed about the diagnostic gaps in standard medicineThis conversation gives you the framework to recognize the warning signs most physicians are still missing, and the foundational habits; nutrition, resistance training, and hormone optimization that protect your gut, bones, and muscle through midlife and beyond.
Thank you to our sponsors:
Cozy Earth -Go to https://bit.ly/4teXQhz for up to 20% off!
Timeline - Get 20% off your Mitopure order at https://bit.ly/4eLBWhB
Lucy -Get 20% off your next order with code DRLYON at https://bit.ly/42HiUlc, or find yours in store at https://bit.ly/3RfGnYa
Amp - Visit https://bit.ly/3RcmqBz to get your AI-powered at-home gym for smarter, personalized training.
Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes contenthttps://foreverstrong.supercast.com
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Apply to become a patient:Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/
Find Dr. Michelle Pearlman at:
Instagram: https://www.instagram.com/michellepearlmanmd/
Website: https://www.primeinstitute.us/
Connect with Dr. Gabrielle Lyon
Instagram:https://www.instagram.com/drgabriellelyon/
TikTok: https://www.tiktok.com/@drgabriellelyon
X (Twitter):https://x.com/drgabriellelyon
Facebook:https://www.facebook.com/doctorgabriellelyon
Chapters
00:00 - Introduction: Colorectal cancer under 50
01:15 - The gastro-metabolic approach explained
03:30 - Why nutrition isn't taught in GI fellowship
05:45 - When the colonoscopy is normal but patients suffer
07:00 - Weight, reflux, and visceral fat
09:15 - PPIs, bone density, and long-term risk
11:30 - Three things to never do for gut health
14:00 - Ultra-processed food and early-onset cancer
16:45 - Rectal bleeding, warning signs, and age
19:00 - Screening guidelines and the obesity gap
22:30 - GLP-1 medications: history and mechanism
27:15 - Hunger, cravings, and food noise
30:00 - The stigma around metabolic medications
33:45 - Side effects: nausea, reflux, constipation
38:30 - Compounded formulations and pharmacy safety
42:00 - Hair loss, protein, and supplementation
45:15 - Pill versus injection delivery systems
49:30 - Fiber, the microbiome, and short-chain fatty acids
54:00 - GLP-1s plus hormone replacement therapy
58:45 - Testosterone, Kyzatrex, and women's bone health
1:03:00 - Pearlman's osteoporosis diagnosis at 39
1:09:30 - The diagnostic gap in standard medicine
1:14:00 - Building Bite MD and the future of nutrition tech
Disclaimers:This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 19 May 2026 - 2h 02min - 206 - Jocko Willink - Parenting, Apex Kid Myth, Failure, & Leadership
Most parents are quietly paving the road their kids were supposed to learn to walk on by themselves and Jocko Willink has spent 20 years watching what happens when that road is too smooth.
In this episode, Dr. Gabrielle Lyon sits down with Jocko Willink, retired Navy SEAL commander, founder of Echelon Front, and bestselling author of Extreme Ownership and Discipline Equals Freedom, to discuss:
Why the "apex parent / apex kid" mindset is a quiet trap, and what to do instead of paving the roadHow nature vs nurture actually plays out and what you can and cannot shape in your childThe one trait Jocko wants his kids to inherit (and why every virtue becomes a vice when pushed to the extreme)The lie that successful, high-functioning people tell themselves about wanting moreThe single most important trait of a great leader and the one habit Jocko says will make every other part of your life better starting tomorrowYou'll walk away with a clearer operating system for the kind of parent, leader, and person you actually want to be and the one habit Jocko swears is the highest-ROI move any human can make.
Thank you to our sponsors:
BodyHealth - Use the code LYON20 to get 20% off your first orderhttps://bit.ly/48SJ7ACOur Place -Visithttps://bit.ly/4c8OrAB and use code DRLYON for 10% off sitewide.Branch Basics -Get 15% off the Premium Starter Kit at https://bit.ly/4eu4Mm8 with the code DRLYON.Amp - Visithttps://bit.ly/41BvjXj to get your AI-powered at-home gym for smarter, personalized training.Watch on Spotify. If you’re subscribed to Spotify Premium, you don’t get any Spotify ads on my video.
Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes contenthttps://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient:Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find JOCKO WILLINK at:
Instagram: https://www.instagram.com/jockowillink/?hl=en
Facebook: https://www.facebook.com/jkowillink/
Tiktok: https://www.tiktok.com/@jocko_willink
X: https://x.com/jockowillink
YouTube: https://www.youtube.com/@JockoPodcastOfficial
Linkedin: https://www.linkedin.com/in/jocko-willink-260b289/
Get Jocko Willink’s books: https://jocko.com/books/
Connect with Dr. Gabrielle Lyon
Instagram:https://www.instagram.com/drgabriellelyon/
TikTok: @drgabriellelyon
X (Twitter):https://x.com/drgabriellelyon
Facebook:https://www.facebook.com/doctorgabriellelyon
Chapters
00:00 - Introduction: Leadership and parenting are the same skill
03:24 - Nature vs nurture and the kids who won't compete
06:56 - The guardrails of failure
07:48 - Dharma and the path kids are meant to walk
09:17 - The one trait Jocko wants his kids to inherit
11:33 - What daughters should learn about men from their fathers
13:32 - How men and women experience fear differently
14:24 - Rebuilding trust after good people do bad things
18:34 - Letting your daughter do cheerleading
21:22 - Hiring people by putting them in the real environment
24:22 - The lie successful people tell themselves
29:16 - Strategic thinking vs the donut decision
35:18 - What failure teaches that success cannot
38:25 - Why Jocko stopped being about himself
44:09 - Aging, losing movements, and rage against the dying of the light
46:49 - Why a leader has to be in physical shape
50:41 - The single most important trait of a leader
54:09 - The one habit that changes everything
If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers:This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 12 May 2026 - 1h 04min - 205 - Doctors Are Removing Testicles for This | Dr. Susan Macdonald
Most men don't know they have a pelvic floor, and most doctors aren't trained to look for dysfunction in it. The result: testicles are being surgically removed for pain that's actually neuropathic, at double the rate of a far more effective nerve-sparing procedure.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Susan Macdonald, a board-certified urologist, surgical program director at Penn State, and one of only ~30 U.S. specialists treating chronic pelvic pain in men, to discuss:
Why "prostatitis" is often the wrong diagnosis, and how rounds of antibiotics mask the real problemThe male pelvic floor anatomy almost no medical school teaches, and how to recognize dysfunction in yourself or a patientOff-label medications (Cymbalta, gabapentin, amitriptyline) that are quietly transforming chronic pelvic pain treatmentWhy erectile dysfunction is rising sharply in teenagers, and the role pornography plays in rewiring young brainsWho actually qualifies for a penile implant, and what the surgery really involvesIf you've been told your pain is "all in your head," or you're a clinician seeing patients fall through the cracks, this conversation gives you the framework, the language, and the next steps to find real answers.
Thank you to our sponsors:
Manukora - Go to https://www.MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts.Timeline - Get 20% off your Mitopure order at https://www.timeline.com/lyonBONCHARGE - Save 15% at https://boncharge.com/ with code DRLYONExplore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Susan Macdonald at:
Instagram: https://www.instagram.com/drsusanmacdonald/
X (Twitter): https://x.com/smacdonald_md
LinkedIn: https://www.linkedin.com/in/susan-macdonald-506324191/
Connect with Dr. Gabrielle Lyon
Instagram: https://www.instagram.com/drgabriellelyon/
TikTok: @drgabriellelyon
X (Twitter): https://x.com/drgabriellelyon
Facebook: https://www.facebook.com/doctorgabriellelyon
Chapters
00:00 - Introduction
01:42 - Meet Dr. Susan Macdonald
03:00 - The high-powered lawyer nobody could help
05:01 - Why testicle pain is 5% of urology visits
07:49 - Men have a pelvic floor (and what it does)
12:46 - How a man knows he has pelvic floor dysfunction
21:30 - Why these muscles are "too tight" in men
26:33 - Chronic pain rewires the brain
29:21 - Stress, trauma, and the mind-body connection
33:29 - Stretching, breathing, and self-treatment at home
36:21 - The medications that actually work (Cymbalta, gabapentin)
44:34 - Muscle relaxers, acupuncture, and the guidelines panel
55:09 - Sexual trauma and chronic pelvic pain
01:00:08 - The "pain plus" diagnostic framework
01:05:23 - The micro-surgical denervation surgery
01:08:36 - Erectile dysfunction in 17-year-olds
01:11:00 - How porn rewires young men's brains
01:18:27 - 40% of men by 40, 50% by 50
01:23:39 - Penile implants: who qualifies, how they work
01:28:10 - Stage 4 cancer at 42 and the pivot to teaching
01:34:17 - Living big with finite time
01:39:00 - Closing message to chronic pain patients
If you found this episode valuable, share it with someone who would benefit from it.
This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 05 May 2026 - 1h 41min - 204 - Mark Bell on Fat vs. Carbs, What’s Really Making You Fat?
Most people are chasing the wrong version of strength and paying for it with pain, poor movement, and a body that breaks down faster than it should. In this episode, Dr. Gabrielle Lyon sits down with Mark Bell, elite powerlifter, entrepreneur, and founder of Slingshot, to discuss:
Why strength training is essential at every age but most people are defining "strength" too narrowlyHow modern life has created an "exercise deficiency," and why artificial exercise is the only fixThe truth about fat, protein, and the biggest nutrition mistakes holding people back from lasting weight lossThe emerging peptide and drug landscape, and what it means for the future of health optimizationWhy forcing your kids to move isn't cruelty, it's one of the most protective things you can do as a parentWhether you're 25 or 75, this episode will challenge how you think about movement, muscle, and what it actually means to be strong physically and mentally.
Thank you to our sponsors:
OneSkin - Get 15% off with code DRLYON — https://bit.ly/4tZnOpkAmp - Get your AI-powered at-home gym for smarter personalized training — https://bit.ly/41BvjXjBranch Basics - Get 15% off the Premium Starter Kit with the code DRLYON — https://bit.ly/4eu4Mm8BodyHealth - Get 20% off your first order with the code LYON 20 — https://bit.ly/4etWlr5Explore More from Dr. Gabrielle Lyon
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content — https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights — https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team — https://drgabriellelyon.com/new-patient-inquiry/Find Mark Bell at:
https://www.instagram.com/marksmellybell/https://www.youtube.com/@MarkBellSuperTrainingSlingshot: https://originmaine.com/Connect with Dr. Gabrielle Lyon
Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters
00:00 – Introduction
02:48 – Mark Bell's Motto
07:00 – Mind-Body Strength Connection
10:45 – Wrestling > Powerlifting > Entrepreneurship Journey
17:37 – Rationale of Goals
22:04 – Effects of Consistency and Efficiency in Training
32:55 – Recommended Training and Lifestyle Modalities
37:32 – Artificial Exercise vs. Exercise Deficiency
37:47 – "Artificial Exercise" and "Exercise Deficiency"
39:36 – Impact of Physical Activity in Children
44:57 – Biggest Mistake in Weight Loss
50:46 – Overconsumption is a Problem
53:17 – Era of GLP-1, Peptides, and Steroids
1:02:28 – Training to Decrease Mortality
1:03:33 – Cancer Research Updates
1:04:36 – Collective Research on Supplementation
1:16:50 – Influencing Children to Engage in Physical Activities
Share This Episode If you found this episode valuable, share it with someone who would benefit from it.
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 28 Apr 2026 - 1h 19min - 203 - GLP-1 Side Effects, Risks, And Who Should Actually Be Using It | Dr. Christle Guevarra
We are living through one of the most significant shifts in medicine in generations, and most people don’t fully understand what it means. Dr. Christle Guevarra joins me to zoom out on the entire GLP-1 landscape; from the drug’s origins as a modest diabetes treatment in 2005 to today’s third-generation medications still moving through clinical trials, and what all of it means for the future of obesity, performance, and longevity.
🙌Thank you to our sponsors:
🌍 Cozy Earth - Go to https://bit.ly/4teXQhz for up to 20% off!
🤍 Timeline - Get 20% off your Mitopure order at https://www.timeline.com/lyon
🚲 Carol Bike - Visit https://bit.ly/4tg4cxa and use code LYON for $100 off your CAROL Bike
Explore More from Dr. Gabrielle Lyon:
Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.com
Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/
Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/
Connect with Dr. Christle Guevarra
YouTube: https://bit.ly/4vDMVQa
Instagram: https://bit.ly/4mxnfAc
Get Dr. Christle Guevarra’s book, “Bodybuilding Anatomy”: https://bit.ly/3ODIDYd
📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
📱Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
TikTok: https://bit.ly/3OFK3kJ
X.com: https://bit.ly/4l3YlaX
Facebook: https://bit.ly/3MBrJso
⏰Timestamps:
00:00 Intro of Show
06:48 Changes in the Fat Loss Landscape
06:54 Engagement in Competitive Powerlifting
11:29 Perspectives on GLP-1 Medication
26:10 Perimenopause Journey
27:13 Topamax
28:03 Urosepsis
30:23 Weight Loss Programming
31:43 Patients' Decision to Take GLP-1
37:44 Risks and Effects on Taking GLP-1
38:10 Pancreatitis
41:40 Fen-Phen (Fenfluramine/phentermine) / Ephedra
45:59 Who Should Not Take GLP-1?
49:24 Proper Nutrition to Support Taking GLP-1
52:14 Recommendation for the New Dietary Guidelines
59:01 Residency and Sports Medicine Fellowship
1:02:38 Are Athletes Recommended to Take GLP-1?
1:08:49 Lack of Randomized, Controlled Trials for Peptides
1:10:38 Key Take-away's from Dr. Christle
1:13:24 Should Women Weigh Themselves?
1:21:02 Should Women Lift Weights?
1:21:55 What's Next for Dr. Christle?
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 21 Apr 2026 - 1h 22min - 202 - Dominique Sachse on Aging Well, HRT, and Building Muscle After 50
The moment you decide to show up publicly, you open the door to opinions from people who would never say those things to your face. Dominique Sachse, journalist, author, and content creator who has lived her life on camera for over three decades, gets honest about what it costs to put yourself out there, why online cruelty is a psychology problem more than a content problem, and how “Teflon Dom” developed the thick skin to let none of it redirect her.
Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSRe
Get Dominique Sachse’s book, “Life Makeover: Embrace the Bold, Beautiful, and Blessed You”: https://bit.ly/4meV7lk
Listen to "Over 50 & Flourishing" on all your favorite platforms!
YouTube: https://bit.ly/4meCeyY
Spotify: https://bit.ly/4cwdvTs
Apple Podcasts: https://bit.ly/4bVin4s
📱Connect with Dominique Sachse:
Website: https://bit.ly/41VFUfC
YouTube: https://bit.ly/41YNk1C
Instagram: https://bit.ly/3OgHXHU
Facebook: https://bit.ly/41G41iB
TikTok: https://bit.ly/4sXBbWB
LinkedIn: https://bit.ly/3PYRvIf
🙌Thank you to our sponsors:
💪BodyHealth - Use the code LYON 20 to get 20% off your first order https://bit.ly/4mhPTVS
🍳Our Place - Our Place - Visit https://bit.ly/4c8OrAB and use code DRLYON for 10% off sitewide
😁Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/48xF5NK with the code DRLYON
❤️Amp - Visit https://bit.ly/4cwLoDJ to get your AI-powered at-home gym for smarter, personalized training
📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
YouTube: https://bit.ly/4boCFC3
Spotify: https://bit.ly/4cWTbLG
📱Connect with Dr. Gabrielle Lyon:
Instagram: https://bit.ly/4uk9adc
TikTok: https://bit.ly/3OFK3kJ
X.com: https://bit.ly/4l3YlaX
Facebook: https://bit.ly/3MBrJso
LinkedIn: https://bit.ly/3N1nrdL
Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 Intro of Show
02:10 Dominique’s Mission
05:13 Women’s Reinvention with Aging
12:07 Handling People’s Opinions in the Media
18:03 Why Dominique Wrote “Life Makeover”
26:08 Activating One’s Faith through Life’s Challenges
29:16 Decision to Leave the News Business
34:12 Traditional Media Transitioning to Online Media
37:09 How to Curate Information
38:42 Effectively Communicating with Journalism and Research Skills
43:17 Managing Conflicts On-and-Off Air
45:28 The Aging Process
49:53 Personal Training with Body Builders
52:33 Changes in Training and Nutrition
54:49 Importance of Discipline
1:00:28 How Dominique Makes Decisions
1:04:03 Dominique’s Goal and Message
1:08:46 Midlife Wellness Protocols
1:14:29 What’s Next for Dominique?
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 14 Apr 2026 - 1h 21min - 201 - The Truth about Saturated Fat, Omega-3 Fatty Acids and Total Mortality | Dr. Tom Brenna
Only nine scientists were asked to advise on the 2025 Dietary Guidelines for Americans, and Dr. Tom Brenna was one of them. In this conversation, he pulls back the curtain on how dietary guidelines are actually made, why the process has never been the same twice, and what it was like to watch a decades-old saturated fat recommendation get carried forward despite a lack of evidence supporting it at the level of total mortality. This is the dietary guidelines conversation the internet has been missing: straight from someone who was actually in the room.
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Website: https://bit.ly/3O3cNUv
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LinkedIn: https://bit.ly/4shYfyl
References:
https://ajcn.nutrition.org/article/S0002-9165(24)00527-6/fulltext
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Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 Intro of Show
00:14 Dr. Tom Brenna’s Background
05:19 Working with IBM
08:46 Family Life
10:38 2015 vs. 2025 Dietary Guidelines for Americans
28:06 American Society for Nutrition: Behind-the-Scenes of Dietary Guidelines
32:10 History of Saturated Fat
42:17 Different Types of Fat
45:23 How Are People Eating during World War II
51:09 The Whole Milk for Healthy Kids Act of 2025
53:58 What is Saturated Fat?
57:57 Link between Saturated Fat and Cardiovascular Diseases
1:05:53 Saturated Fat vs. Total Mortality
1:13:13 Best Studies on Saturated Fat
1:14:42 Reduction of Saturated Fat = Lowered LDL Cholesterol
1:22:35 Pregnancy and Fish Consumption Myths
1:37:55 Recommended Nutrition
1:39:59 Different Types of Oil and Effects on Health
1:42:04 Omega 3’s and 6’s Recommendation
1:50:02 Omega 3 Fatty Acids and ADHD
1:50:54 What’s Next: Precision Nutrition and Genetics
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 07 Apr 2026 - 1h 31min - 200 - GLP-1 Drugs & Bariatric Surgery Explained by a Top Obesity Researcher | Dr. David Allison
In a world flooded with conflicting health advice, how do you actually figure out what’s true? Dr. David Allison, one of the most rigorous scientific minds in obesity and nutrition research, shared the exact framework he uses to evaluate evidence, from peer-reviewed trials to podcast recommendations to AI-generated summaries. He explains the difference between trusting science as a process and trusting individual studies, why most nutrition epidemiology functions more like advertising than research, and how ordinary people can build a reliable filter for health claims without a PhD.
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📱Connect with Dr. David Allison
LinkedIn: https://bit.ly/3O6quC2
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Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 Intro of Show
03:55 Dr. David Allison’s Background
09:50 Principles vs. Scientific Data
14:48 What is Doubly-Labeled Water?
16:42 Misconceptions on Diet
21:08 Concept of Human Discomfort
24:18 Childhood Obesity
28:49 Research: What Really is the Purpose?
31:14 Can We Trust Science?
40:54 INSERT LINK: NEWSLETTER ON OBESITY AND ENERGETICS
40:54 Obesity: Causes and Treatments
50:29 Different Outcomes from Weight Loss Drugs
57:21 Safety is a Social Judgment
1:00:18 Making Decisions in a Noisy Landscape
1:08:29 Podcasts as a Good Source of Information
1:16:09 Stance on Ultra-Processed Foods and Seed Oils
1:22:50 Dr. David’s New Projects
1:29:40 How to Make Good Decisions
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 31 Mar 2026 - 1h 35min - 199 - Dr. Tommy Wood: Can Cognitive Decline Be Reversed?
Up to 70% of dementia may be preventable, so why aren’t more people talking about what actually drives cognitive decline? In this episode, I’m with Dr. Tommy Wood, neuroscientist and author of “The Stimulated Mind,” to explore the lifestyle levers that protect your brain across a lifetime. Learn how white matter hyperintensities develop and whether they can reverse, what MCTs and ketones actually do for a glucose-starved brain, and why social connection may be the most underrated variable in cognitive aging. What is the one change you could make today that would most protect your brain tomorrow?
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Get Dr. Tommy Wood’s book, “The Stimulated Mind”: https://bit.ly/4bYIUxE
Listen to "Better Brain Fitness" on all your favorite platforms!
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📱Connect with Dr. Tommy Wood:
Website: https://bit.ly/3NIV4RX
YouTube: https://bit.ly/3NVWWHa
Instagram:https://bit.ly/40L6w2z
LinkedIn: https://bit.ly/4c0iETw
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 Intro of Show
01:52 Elite Athlete’s Brain and Emotional Regulation
06:51 How to Regulate Emotions
11:30 Mindset Impacting Hormonal Responses
15:39 Future-Proofing the Brain
19:42 Brain Development vs. Shrinkage
26:11 Dementia Types, Causes, and Prevention
39:29 Social Isolation Influencing Cognitive Function
50:00 Social Stress’ Drivers
52:34 Non-Negotiable’s to Avoid Dementia Risks
57:42 Seafood Consumption Beneficial for Brain Function
1:03:35 Alcohol and Sleep Impacting the Brain
1:10:16 Is Brain Function Recovery Possible?
1:18:43 Use of Ketones and Glucose for Cognitive Recovery
1:23:09 Power of Mindfulness
1:27:06 Get Dr. Wood’s Book
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 24 Mar 2026 - 1h 30min - 198 - HIIT vs. Moderate Intensity Exercise - Which Is Better for Your Health? | Dr. Martin Gibala
Metabolic flexibility is your body’s ability to efficiently burn fat or carbohydrate depending on demand, may be one of the most important and least understood markers of long-term health. In this episode, I’m with Dr. Martin Gibala to explore the emerging science of Fat Max, why mitochondrial quality is central to both performance and longevity, and how sprint interval training produces comparable mitochondrial adaptations to traditional endurance work in a fraction of the time. Could the key to better metabolic health be less about the hours you log and more about how hard you’re willing to push?
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Get Dr. Martin Gibala’s book, “The One-Minute Workout” here: https://bit.ly/4lxBchq
Connect with Dr. Martin Gibala
Website: https://bit.ly/3P8ROjd
Website: https://bit.ly/3Nfz410
Instagram: https://bit.ly/40qrVhl
X.com: https://bit.ly/4b9usCP
YouTube: https://bit.ly/3PiVkYh
Email: realexercisescience@gmail.com
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 Intro of Show
01:26 What is High-Intensity Interval Training?
05:04 HIIT to Improve Health Fundamentally
08:23 Exercise Ratio for General Individuals vs. Athletes
14:29 Dr. Lyon's Workout Routine
16:47 High-Intensity Interval vs. Sprint Interval Training
20:23 New Studies on Sprint Interval Training
24:57 The One-Minute Workout
26:57 CAROL Bike Mechanics
28:59 Benefits of High-Intensity Interval Training
37:21 Fuel Utilization: Sprint Interval vs. Slow, Steady-State Training
45:38 Metabolic Flexibility Definition
46:41 Fat Max Definition and Evaluation
50:26 Zone Training Model
58:00 Designing the Health of the Nation
1:04:04 How to Improve Body Composition
1:11:40 REHIT: Reduced Exertion, High-Intensity Training
1:21:59 Does HIIT Prevent Sarcopenia?
1:27:27 VO2 Max: Factoring Age and Sex
1:34:28 Designing the Ideal Workout Week
1:39:14 Importance of Rest Intervals
1:45:14 Connect with Martin
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 17 Mar 2026 - 1h 46min - 197 - Danica Patrick Opens Up About Breast Implant Illness, Inflammation, and Starting Over
The most decorated woman in motorsports history will tell you she feared losing far more than she loved winning, and that fear is exactly what drove her to the top. In this episode, I’m with racing legend Danica Patrick to unpack the psychology of elite performance, from the “blind faith” that carried her through two decades of racing to the nervous system conditioning she built starting at age 10. What would be possible for you if you learned to channel pressure instead of escaping it?
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YouTube: https://bit.ly/4cyZPrt
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Apple Podcasts: https://bit.ly/4s4I1cH
Get Danica Patrick’s book, “Pretty Intense” here: https://bit.ly/4rXdH3r
📱Connect with Danica Patrick
Website: https://bit.ly/4lfA9SQ
YouTube: https://bit.ly/3OVYeCk
Instagram: https://bit.ly/4bht0Ni
TikTok: https://bit.ly/4sCyDNf
Facebook: https://bit.ly/3Nuajhw
X.com: https://bit.ly/3Pdog3X
LinkedIn: https://bit.ly/4cWK6mn
🙌Thank you to our sponsors:
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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📱Connect with Dr. Gabrielle Lyon:
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Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
00:00 Intro of Show
02:05 Understanding the Idea of Pressure and Challenge as a Kid
05:00 Managing Wins and Losses
09:45 Automaticity to Fear
11:44 Managing Nervous System under High Pressure
17:34 Danica's Pre-Performance Rituals
20:21 Performance Becoming One's Identity
21:23 Danica Working with Dr. Lyon
26:24 Discipline for Proper Recovery
28:47 Tips for Someone Going through the Same Issues
31:01 Working with Different Doctors
34:01 Women's Intuition in Hiring
37:14 Women in Male-Dominated Industries
41:42 There Are No Shortcuts to Success
43:01 Performing in High-Pressure Situations
45:51 Importance of Having Alone Time
48:34 What is Home Energy?
51:20 Flow of State: Passion and Creativity
55:51 Medicine in the AI Era
59:32 Rapid Fire Q&A
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 10 Mar 2026 - 1h 04min - 196 - Hormone Replacement Therapy, What Every Woman Needs to Know in 2026 | Dr. Heather Hirsch
I’m joined by Dr. Heather Hirsch to debunk the persistent myths surrounding hormone replacement therapy and explain why the 2002 Women’s Health Initiative data was so widely misinterpreted. We discuss how optimized estrogen, progesterone, and testosterone levels can protect your heart, bones, and brain health, helping you move past "normalized suffering" and into a proactive state of longevity. Whether you are in perimenopause or well past the ten-year window, you'll learn how to navigate personalized dosing and clinical data to reclaim your vitality and extend your health span.
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Listen to “Women’s Health by Heather Hirsch, MD” on all your favorite platforms!
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Get Dr. Heather Hirsch’s book, “The Perimenopause Survival Guide” here:
📱Connect with Dr. Heather Hirsch:
Website: https://bit.ly/4smy4qJ
YouTube: https://bit.ly/3NdevSH
Instagram: https://bit.ly/4sfj11P
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📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:
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Website: https://bit.ly/3NdV2kT
Books: https://bit.ly/4r6ugZK
Newsletter: https://bit.ly/402QCAj
⏰Timestamps:
0:00 Intro of Show
6:00 Hormone Replacement Therapy: Where Are We Now?
11:25 What is Menopausal Hormone Therapy?
13:39 How Safe is Hormone Replacement Therapy?
18:39 Access on the Studies on HRT
23:10 Risks of Hormone Replacement Therapy
27:24 Estrogen Does Not Cause Breast Cancer
31:19 Estrogen and Accelerated Bone Loss
34:51 Preventative Benefits of Estrogen
38:47 Lifespan vs. Health Span
39:22 When to Start Hormone Replacement Therapy?
45:15 Blood Markers
47:26 Progesterone: Effects, Timing, Dosage
52:38 Testosterone: Effects, FDA Approval, Benefits, Risks
1:00:44 Analysing the Numbers
1:04:13 Link of HRT and Cognitive Function
1:09:28 What Are Women Doing Wrong?
‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 03 Mar 2026 - 1h 11min - 195 - Male Fertility and Sperm Health: What Your Sex Drive and Testosterone Really Mean | Dr. Michael Eisenberg
Male fertility is declining, and most men have no idea why.
In this episode of The Dr. Gabrielle Lyon Show, Dr. Gabrielle Lyon sits down with Dr. Michael Eisenberg, Director of Male Reproductive Health at Stanford University and Chief Medical Advisor of SwimClub, to break down what truly determines sperm health and reproductive success.
They discuss:
- How metformin, GLP-1 medications, testosterone therapy, and anabolic steroids affect male fertilityWhy sperm count is a powerful biomarker for long-term health and longevityThe role of sleep, muscle mass, exercise, diet, marijuana, and environmental toxins like microplasticsWhether platelet-rich plasma, or PRP, can help severe male infertilityDaily habits that quietly reduce a couple’s chances of conceiving
If you care about fertility, hormones, metabolic health, or the future of men’s health, this conversation is essential.
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Thank you to our sponsors:
- BodyHealth - Get 20% off your first order with code LYON20 https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/Carol Bike - Visit https://carolbike.com/ and use code LYON for $100 off your CAROL BikeOneSkin - Get 15% off at https://www.oneskin.co/ with code DRLYON
Find Dr. Michael Eisenberg at:
- Eisenberg Lab: https://med.stanford.edu/eisenberglab.htmlLinkedIn: https://www.linkedin.com/in/michael-eisenberg-9230a429X: https://x.com/DrMEisenberg
Find Dr. Gabrielle Lyon at:
- Instagram:@drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageOrder my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623
Chapters:
00:00 Sex habits, libido, GLP-1s, and what counts as male infertility
01:46 Metformin and male fertility, what the Denmark study found
07:27 How long sperm take to regenerate after meds, illness, or chemo
09:24 GLP-1 medications, weight loss, and semen quality in men
10:52 Testosterone therapy, anabolic steroids, and why sperm shuts down
16:41 Sperm as a vital sign, fertility as a window into long term health
19:14 Microplastics and environmental toxins found in semen
22:21 Paternal age and sperm quality, DNA fragmentation and pregnancy risk
26:03 Supplements and nutrients for sperm quality, what matters and why
30:00 Sex frequency, masturbation, libido, and fertility myths
35:38 Male infertility guidelines and medications that quietly lower fertility
48:41 Semen quality and future disease risk, diabetes, cancer, mortality
54:45 Anabolic agents, sperm banking, and how long frozen sperm lasts
1:04:14 PRP for severe male infertility, azospermia and real outcomes
1:16:41 New frontiers in male fertility, immune profiles, genomics, omics
Disclaimers:This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 24 Feb 2026 - 1h 19min - 194 - Why You Don’t Believe in Yourself (And How to Fix It) | Dr. Shadé Zahrai
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Self-doubt holds more people back than lack of skill or intelligence.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Shadé Zahrai to explore the science of confidence, self-trust, and peak performance. They break down why confidence comes after action, how self-image shapes success, and the four psychological drivers that determine whether you thrive or stay stuck.
You will learn how body language influences perception, why high performers plan for failure, how perfectionism leads to burnout, and the subtle communication habits that undermine credibility. Most importantly, you will discover how to build what Dr. Zahrai calls Big Trust so you can back yourself before you feel ready.
If you struggle with overthinking, imposter thoughts, or feeling capable but not fully confident, this conversation will give you practical tools to change how you show up.
CHAPTERS
00:00 Confidence science: feeling vs appearing
00:51 The opposite of self-doubt and why confidence comes after action
01:53 Self-trust before confidence
03:03 Nonverbal confidence cues: posture, eye contact, smile, pace
07:30 Body language feedback loop: posture and recall
09:26 Shadé’s PhD on self-doubt under pressure
12:22 What makes people successful: self-image
12:30 Self-image blueprint and why change does not stick
14:29 The Four A’s: Acceptance, Agency, Autonomy, Adaptability
20:26 The self-awareness gap and changing personality traits
22:30 Expectation bias and the scar experiment
25:54 Self-doubt types: signal vs verdict
28:30 Visibility, influence, and the people around you
31:16 Which traits are easiest to change
35:56 Why capable people still stay stuck
40:25 Michael Phelps and visualizing failure recovery
42:30 Stop rumination: stimulus control for worry
47:45 Self-improvement vs perfectionism vs burnout
56:53 The 4 inner deceivers: Judge, Protector, Neglecter, Ringmaster
1:11:22 Peak performance and Big Trust
1:19:19 Communication habits that kill credibility
1:24:18 Stop over-apologizing and reframe emotion
1:29:47 Daily habits to build Big Trust and audit your circle
Thank you to our sponsors:
- Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyonBodyHealth - Get 20% off your first order with code LYON20 https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/Four Sigmatic - Go to http://foursigmatic.com/gabrielle for a free bag of their dark roast ground coffee with a subscription (just pay for shipping & handling).
Find Dr. Dr. Shadé Zahrai at:
- IG: https://www.instagram.com/shadezahrai/YouTube: https://www.youtube.com/shadezahraiBig Trust by Dr. Shadé Zahrai gives you the tools to quiet self-doubt and step forward with clarity, agency, and confidence. Get your copy here: https://www.amazon.ca/Big-Trust-Self-Doubt-Confidence-Success/dp/0063378159
Find Dr. Gabrielle Lyon at:
- Instagram: @drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 17 Feb 2026 - 1h 34min - 193 - How to Eat for Strength, Metabolism, and Longevity
Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com
This episode brings together standout moments from The Forever Strong Experience,packed into one powerful episode.
Featuring highlights from:
- Dr. Mark Hyman – Founder of the Cleveland Clinic Center for Functional Medicine, co-founder and CMO of Function Health, director of The UltraWellness Center, host of The Dr. Hyman Show (300M+ downloads), and 15x New York Times bestselling author, including Young Forever and Food Fix Uncensored.Layne Norton, PhD – Nutritional scientist, 4x USA Powerlifting National Champion and 2024 IPF M1 World Champion (93kg), record-setting deadlifter, coach to 1,700+ clients, and founder of Outwork Nutrition.Michelle Shapiro, RD – Integrative/functional dietitian who helps clients reverse anxiety, heal complex gut and immune issues, and approach weight with compassion. Host of the Quiet the Diet podcast.Alan Aragon, MS – Veteran nutrition researcher, co-author of 30+ peer-reviewed papers (including JISSN’s most-viewed article), ISSN Position Stand lead author, and founder of Alan Aragon’s Research Review and the Fit Advancement Mentorship (FAM).
In this mashup, they break down:
- How to eat for long-term metabolic and muscle healthWhy protein and resistance training are non-negotiables as you ageThe role of stress, mindset, and past experiences in how you eat and feelWhat it really means to be “forever strong” in body and mind
Perfect if you’re tired of conflicting nutrition advice and want clear, evidence-based guidance you can actually use.
Thank you to our sponsors:
Our Place -Visit https://www.fromourplace.com/DRLYON and use code DRLYON for 10% off sitewide.
Four Sigmatic - Go to http://foursigmatic.com/gabrielle for a free bag of their dark roast ground coffee (just pay for shipping & handling).
Cozy Earth -Go to https://www.cozyearth.com/DRLYON for up to 20% off!
Chapters:
00:00:00 The truth about nutrition
00:01:06 Why is it so hard to follow health advice?
00:03:07 What actually holds people back from progress?
00:05:26 When “clean eating” backfires
00:05:57 The nutrition “rule” that does more harm than good
00:06:37 Why medicine got obsessed with BMI and fat
00:08:47 Body composition fundamentals: what to do first
00:10:53 “Rules” for better body composition (practical guidelines)
00:13:20 Do you have to lift heavy to build muscle?
00:16:24 Strength vs hypertrophy: what matters most as you age
00:17:46 Sponsor: Our Place + What if muscle were taught as an organ system?
00:20:14 Is obesity actually the root cause?
00:21:24 Midlife: why “nothing’s working” (what’s really happening)
00:23:21 Is it metabolic change or lifestyle, sleep, and stress?
00:28:40 The most impactful shift for a muscle-centric nutrition plan
00:30:44 Food anxiety: can you scare yourself into being fit?
00:32:41 Digestion and absorption: making a muscle-centric lifestyle work
00:33:42 The truth about nutrition: eat real food, food is medicine, personalize
00:36:23 Sponsor: Four Sigmatic + Biggest myths in training and nutrition
00:44:06 One thing to stop doing immediately
00:45:31 Stress and the nervous system: how it affects digestion
00:46:29 Practical tips for staying consistent under high stress
00:48:09 The danger of sarcopenia (where we’re headed)
00:50:14 Midlife expectations: slower progress, better strategy
00:53:52 The long-term impact of eliminating food groups
00:55:04 Healing vs cutting foods: what to do instead
00:57:15 Sponsor: Cozy Earth + The myth you wish would die
01:01:21 Travel: how to create “safety” and stay fed
01:02:37 The airport backup plan (the “oh no” foods list)
01:04:49 Expected challenges: planning so you don’t act surprised
01:06:03 Boundaries and resistance training: what’s the standard?
01:07:43 Mindset, trauma, and wellness (ACE questionnaire)
01:13:13 Final question: What does “Forever Strong” mean to you?
Find Dr. Mark Hyman:https://www.instagram.com/drmarkhyman/
Find Layne Norton: https://www.instagram.com/biolayne/
Find Michelle Shapiro: https://www.instagram.com/michelleshapirord/
Find Alan Aragon https://www.instagram.com/thealanaragon/
Find Dr. Gabrielle Lyon at:
- Instagram: @drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Order The Forever Strong PLAYBOOK - https://drgabriellelyon.com/playbook/
Tue, 10 Feb 2026 - 1h 17min - 192 - Protein First: How the New Dietary Guidelines Shift Nutrition
Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com
In this episode, Dr. Gabrielle Lyon sits down with Dr. Donald Layman, one of the world’s leading protein researchers and a key contributor to the newly released U.S. Dietary Guidelines. They explore why the old food pyramid failed, how nutrition science became driven by ideology instead of evidence, and what the updated guidelines finally get right about protein, fats, and carbohydrates. Dr. Layman explains why the long-standing protein recommendation of 0.8 g/kg was never intended for optimal health and how higher protein intake supports body composition, metabolic health, and nutrient adequacy.
The conversation also dives into controversial topics including saturated fat, carbohydrate tolerance, animal versus plant protein, and the limitations of epidemiology in nutrition research. Gabrielle and Dr. Layman discuss how dietary guidelines shape school lunches, hospitals, and public institutions, and why a protein-first framework empowers individuals to make better nutrition decisions, especially as we age. This episode offers a clear, science-backed roadmap for understanding modern nutrition — cutting through misinformation and outdated dogma to focus on strength, longevity, and real-world application.
Thank you to our sponsors:
Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyon
Bon Charge - Save 15% at https://boncharge.com/ with code DRLYON
Manukora - Go to https://www.MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts.
Chapters:
00:00 Why Dietary Guidelines Exist and Why This Moment Matters
01:20 The Hidden Origins of the Food Pyramid (World War II + Public Health)
02:55 The Original Protein RDA: A Basement Number, Not Optimal Health
05:50 Why the Old Guidelines Focused on What Not to Eat
07:25 Why Protein Was Avoided for Decades
08:50 Nitrogen Balance: Why It Never Predicted Health Outcomes
11:10 Epidemiology vs Controlled Trials in Nutrition Science
13:05 How the Protein Evidence Was Evaluated for the New Guidelines
14:15 Why Higher Protein Improves Weight, Fat Loss, and Lean Mass
15:35 Is “Too Much Protein” Actually Dangerous?
16:40 Nutrient Deficiencies Risk on Low-Protein Diets
17:35 Animal vs Plant Protein: Bioavailability and Amino Acids
18:45 Why 0.8 g/kg Was Never Better Than Higher Protein
20:15 Empowering Consumers Instead of One-Size-Fits-All Nutrition
21:10 How Guidelines Shape School Lunches, Hospitals, and the Military
23:05 Protein-First Meal Planning Explained
24:50 Why the First Meal Matters More as You Age
27:15 Does Protein Distribution Matter After 50?
30:00 Protein, Satiety, and Appetite Control
31:05 Why “Ounce Equivalents” Between Plant and Animal Protein Don’t Work
34:05 The Saturated Fat Myth and Why the 10% Rule Persists
38:30 Where Saturated Fat Really Comes From in the Modern Diet
39:45 Updated Fruit, Vegetable, and Grain Recommendations
40:45 Carbohydrate Tolerance and Energy Needs
42:45 Why RDAs, DRIs, and Guidelines Create Confusion
44:20 Politics, Institutions, and Resistance to Change
46:10 Why These Guidelines Are Different This Time
47:25 Science Over Ideology: What the Report Gets Right
48:35 Where to Find the Full Guidelines and Supporting Evidence
50:50 Final Takeaway: Protein as the Organizing Principle of Nutrition
Find Dr. Layman on X:https://x.com/donlayman
Find Dr. Gabrielle Lyon at:
- Instagram: @drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Order The Forever Strong PLAYBOOK - https://drgabriellelyon.com/playbook/
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 03 Feb 2026 - 51min - 191 - The Forever Strong PLAYBOOK: Your 6-Week Field Manual for Muscle-Centric Longevity
Order The Forever Strong PLAYBOOK: https://drgabriellelyon.com/playbook/
Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com
In this solo episode, Dr. Gabrielle Lyon shares the deeper mission behind The Forever Strong PLAYBOOK and the philosophy that has guided her work for decades.
This conversation is not about trends, quick fixes, or aesthetics. It is about building strength as a lifelong responsibility and understanding why skeletal muscle is the foundation of health, resilience, and independence across the lifespan.
Dr. Lyon introduces the Forever Strong ethos and walks through the four foundational pillars that support a strong life: how to think, how to eat, how to move, and how to recover. She explains why information alone does not change behavior and why clarity, discernment, and disciplined action are the true drivers of lasting health.
Throughout the episode, Dr. Lyon challenges conventional narratives around aging, nutrition, exercise, and recovery. She reframes longevity through the lens of muscle span, the length of time a person lives with healthy, functional skeletal muscle, and explains how physical strength supports metabolic health, emotional regulation, and cognitive resilience.
This episode is an invitation to step out of confusion and into a clear framework for living with intention. Strength is not something we inherit. It is something we build, choice by choice, day by day.
Thank you to our sponsors:
- Timeline -Get 35% off a Mitopure subscription at https://www.timeline.com/drlyonFour Sigmatic - Go to http://foursigmatic.com/gabrielle for a free bag of their dark roast ground coffee (just pay for shipping & handling).
Find Dr. Gabrielle Lyon at:
- Instagram:@drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyon
Timestamps:
00:00 – The Forever Strong Mission
01:15 – The Forever Strong Ethos
06:00 – Muscle as the Organ of Longevity
09:40 – How to Think
10:24 – Using the Body to Train the Mind
19:41 – Discernment and Mental Strength
28:43 – How to Eat
38:10 – Protein, Carbohydrates, and Metabolic Health
48:04 – Food Quality and Nutrient Density
51:30 – How to Move
57:59 – Training for Strength and Sustainability
1:06:39 – How to Recover
1:12:00 – Forever Strong
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 27 Jan 2026 - 1h 12min - 190 - You Don’t Need Confidence, Just Do THIS | Leila Hormozi
Pre-order The Forever Strong PLAYBOOK today to unlock over $400 in free bonuses and learn how to build the muscle, resilience, and metabolic health that actually determine how well you age. https://drgabriellelyon.com/playbook/
Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com
In this episode, Gabrielle Lyon sits down with Leila Hormozi to discuss the journey from grit to empathy in both personal and professional life. Leila shares candid stories of building her first business, the sacrifices involved, and how her experiences in fitness shaped her entrepreneurial mindset. The conversation explores the value of failure, the importance of discipline, and what it truly takes to achieve business success, reflecting on the unique challenges and rewards that women encounter in leadership roles.
Gabrielle and Leila also open up about balancing ambition, relationships, and personal well-being. They address how to build trust, practice self-belief, and handle the pressures of being public figures with authenticity. You will find practical insights on navigating discomfort, the importance of continuous growth, and on creating a fulfilling life based on clear priorities and honest reflection. The episode is filled with relatable stories and actionable advice for anyone focused on self-development and leadership.
Chapters:
0:00 – From Grit to Empathy: How Leila’s Perspective Shifted
1:33 – Why Fitness Built the Foundation for Business Success
3:38 – Confidence, Self-Belief, and the Difference Between Rookie and Seasoned Entrepreneurs
8:23 – Discomfort, Anxiety, and Paying the Price for Growth
12:58 – Becoming Public-Facing and Outgrowing the Persona You Created
16:01 – Creating Content Without a Funnel or Ego-Driven Motives
19:32 – Why Fewer Women Teach Business at Scale
22:42 – What Actually Makes a Business Legitimate
24:23 – Trust, Relationships, and Learning to Trust Yourself
26:38 – Success vs Happiness and the Tradeoffs People Ignore
31:56 – Sacrifice by Season: Constraints, Focus, and Capacity
35:14 – Personal Trade-Offs and the Real Cost of Success
36:50 – Growth Levels Are About Exposure, Not Time
37:25 – Why You Should Stress Yourself Out More (Short-Term)
43:04 – Social Media, Authenticity, and Being Fully Human
46:15 – Reading Psychology and Understanding Culture
48:19 – Maintaining Relationships Between High Achievers
54:19 – Renegotiating Relationship Roles as Life Evolves
59:54 – Belief Is an Output, Not an Input
1:04:07 – Changing Your Relationship With Discomfort
1:04:55 – What’s Next: Expansion, Health, and Long-Term Vision
Thank you to our sponsors:
- OneSkin - Get 15% off at https://www.oneskin.co/ with code DRLYONBodyHealth - Get 20% off your first order with code LYON20 https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/Bon Charge - Save 15% at https://boncharge.com/ with code DRLYON
Find Leila Hormozi at:
Find Dr. Gabrielle Lyon at:
- Instagram: @drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 20 Jan 2026 - 1h 07min - 189 - Willpower vs. Systems: Why Your Diet Fails & How to Fix Your Relationship w/ Food | Sohee Carpenter
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/
Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com
In this episode, Dr. Gabrielle Lyon is joined by Sohee Carpenter, PhD, to explore the complex intersection of psychology, eating behavior, and resistance training. Dr. Carpenter shares her personal journey from struggling with eating disorders to becoming a leading expert in sports science, offering a unique perspective on why high achievers often struggle with diet adherence.
They dive deep into the science of behavior change, emphasizing that willpower is a finite resource and that true success lies in building automatic, cognitively effortless habits. Dr. Carpenter debunks common fitness myths, including the necessity of "lifting heavy" and the supposed ineffectiveness of circuit training, while providing practical strategies like "habit stacking" and "designing for laziness" to help listeners navigate their own health journeys.
Chapter Markers
- 0:00 - Intro: The finite nature of exercise vs. the 24/7 challenge of nutrition.
- 1:22 - Meet Sohee Carpenter, PhD: Her academic journey from Stanford Biology to a PhD in Sports Science.
- 4:33 - Personal Struggles: Overcoming anorexia, bulimia, and long-term binge eating.
- 5:41 - Cultural Pressures: Growing up with the beauty standards of Korea vs. the US.
- 8:38 - The Fitness Hobbyist: Discovering weights and the "clean eating" trap in 2011.
- 13:10 - The Career Pivot: Choosing Psychology and Fitness over Medical School.
- 17:52 - The Binge-Restrict Cycle: Why trying "harder" and being stricter backfires.
- 21:54 - Defining RMR: Understanding Resting Metabolic Rate as your caloric floor.
- 29:26 - Binge Eating Triggers: Emotion regulation and poor stress coping mechanisms.
- 33:10 - The Freedom of No "Food Noise": Intuitive eating as a learned skill.
- 36:08 - Gentle Nutrition: The "Add, Don’t Restrict" mindset.
- 38:46 - The Willpower Battery: Why habits are superior to brute force discipline.
- 45:47 - Habits and Environment: How to "Design for Laziness".
- 50:00 - Habit Stacking: Pairing new behaviors with existing daily rituals.
- 55:04 - Last Chance Syndrome: The logic of a binge and the "all or nothing" mentality.
- 1:00:13 - Cognitive Distortions: Catastrophizing and the "bird's eye view" reframe.
- 1:04:36 - Dichotomous Thinking: Why black-and-white mindsets lead to binging.
- 1:06:48 - Intrinsic vs. Extrinsic Motivation: Finding a "why" that lasts.
- 1:12:34 - Identity Change: Perceiving yourself as the person you want to become.
- 1:14:27 - Resistance Training for Women: Determining the ideal frequency and style.
- 1:19:16 - National Muscle Health Month: Elevating muscle as a pillar of health.
- 1:21:39 - The "Heavy Lifting" Myth: Using rep ranges and reps in reserve (RIR).
- 1:26:13 - The Circuit Training Study: Similar muscle gains in 25 minutes less time.
- 1:29:44 - Training Fasted: Dispelling misconceptions for women’s metabolic health.
- 1:30:57 - Running while Pregnant: Staying capable and medically cleared.
- 1:33:34 - Final Takeaways: Incremental change and a holistic view of health.
Thank you to our sponsors:
Four Sigmatic - Go to http://foursigmatic.com/gabrielle for a free bag of their dark roast ground coffee (just pay for shipping & handling).
Cozy Earth - Go to https://www.cozyearth.com/DRLYON for up to 20% off!
Our Place - Visit https://www.fromourplace.com/DRLYON and use code DRLYON for 10% off sitewide.
Find Sohee Carpenter at:
- IG: https://www.instagram.com/soheefit
- Youtube: @SoheeFit
Find Dr. Gabrielle Lyon at:
- Instagram:@drgabriellelyon
- TikTok: @drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- YouTube: youtube.com/@DrGabrielleLyon
- X (Twitter): x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
- Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions. This episode includes paid sponsorships.
Tue, 13 Jan 2026 - 1h 35min - 188 - The Gut-Muscle-Immune Axis: How Mitophagy Rewires Your Body for Longevity
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/
Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com
Are your immune cells aging faster than you are? In this episode, Dr. Gabrielle Lyon sits down with Dr. Anurag Singh, a leading physician-researcher and Chief Medical Officer at Timeline, to discuss a groundbreaking discovery: the gut-muscle-immune axis.
While we often focus on muscle mass for longevity, new research published in Nature Aging reveals that our immune system undergoes a similar decline, with youthful sentinel cells (naive CD8 T-cells) dropping by 75% as we reach age 50.
Dr. Singh explains how mitophagy —the targeted recycling of damaged mitochondria—is the key to "rewiring" an aging immune system to fight infection 20% more effectively. In this episode: Alzheimer’s of the Muscle: Why sporadic inclusion body myositis (sIBM) is often misdiagnosed as simple aging.
The Power of Urolithin A: How this postbiotic compound induces mitophagy to increase mitochondrial abundance by 20% in just 28 days. Immune Imprinting: Why children get 6-8 colds a year while adults only average 2-4. Repurposing Longevity Drugs: Dr. Singh’s take on Metformin, Rapamycin, and GLP-1s for life extension. The 1:1 Exercise Rule:Why 150 minutes of moderate activity is the threshold for mitochondrial biogenesis.
Thank you to our sponsors:
BodyHealth - Use the code LYON 20 to get 20% off your first order https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/
Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyon
Manukora - Go to https://www.MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts.
Chapters:
0:00 - Can You Tell If Your Immune System Is Healthy?
1:37 - Alzheimer’s of the Muscle: Muscle-Immune Dysfunction
5:59 - The Thymus Design Flaw: Why Our Immune "Ammo" Disappears
8:44 - Naive CD8 T-Cells: The Elite Forces of Immunity
12:24 - The Axis of Aging: Mitochondria and Immune Cells in Muscle
16:15 - Mitophagy vs. Autophagy: Targeted Cellular Recycling
19:11 - Study Review: Rewiring the Immune System with Urolithin A
24:13 - Mitochondrial Remodeling: Switching from Glucose to Fatty Acids
27:45 - The Trifecta: Gut-Muscle-Immune Axis Connection
31:13 - Parkinson’s and the PINK1/Parkin Mitophagy Pathway
35:04 - Clinical Results: Improving Leg Strength in 4 Months
38:51 - Joint Health: Can We Remodel Cartilage with Mitophagy?
43:34 - Targeted Mitophagy Inducers: Exercise vs. Postbiotics
46:44 - Precision Nutrition: The Ideal Muscle Longevity Supplement
53:33 - Why Alzheimer’s is Now Considered an Inflammatory Disease
1:00:13 - The Placebo Effect: You Cannot Deceive the Immune System
1:03:13 - Lymphocyte Counts: The Clinical Marker for Immune Aging
1:08:14 - Rapamycin and Metformin: The Future of Longevity Drugs
1:11:42 - Optimal Dosing: Why 1,000mg of Urolithin A is the Standard
1:15:13 - Sports Medicine: Reducing Muscle Damage Markers (Creatine Kinase)
1:20:03 - The Final Frontier: Brain Aging and Selenium Repair
Connect with Dr. Anurag Singh
Instagram: @timeline_longevity
Website: https://www.timeline.com
Find Dr. Gabrielle Lyon at:
- Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 06 Jan 2026 - 1h 23min - 187 - The Joint Health Blueprint: Preventing Arthritis, Frozen Shoulder, and Bone Loss as You Age
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/
Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com
If you are only focusing on building muscle, you are missing half the equation for long-term mobility. In this mashup episode, Dr. Gabrielle Lyon brings together top orthopedic experts to discuss the critical importance of joint and tendon health.
While muscle develops relatively quickly, your tendons and ligaments can take 6 to 9 months to fully adapt to a new training stimulus. This gap is where most injuries happen. We dive deep into the biological mechanics of tendons, the"athletic accommodation timeline," and why you must progressively overload your connective tissue—not just your muscle bellies.
You will learn:
- The Menopause Connection: Why women face a 30% higher risk of arthritis and rapid bone loss after age 50, and the role of estrogen in joint inflammation.Osteoporosis Prevention: Why high-impact "flight" exercises (jumping) are more effective for bone density than traditional lifting alone.The Frozen Shoulder Mystery: How to identify the warning signs and why this condition is often linked to hormonal shifts rather than trauma.Injury Recovery & Prehab: The truth about PRP, needle tenotomy, and the "anti-fragility" mindset needed to build a resilient body.The History of Muscle: How ancient Greek views of "pneuma" and the "gift of strength" shaped our modern misunderstanding of movement.
Stop training until you break. Learn how to track your progress, prioritize stability over raw mobility, and design a life built for anti-fragility.
0:00 - The Gap Between Muscle and Tendon Adaptation
1:32 - What Are Tendons? Visco-Elasticity and Force Dissipation
4:36 - The Rotator Cuff: Stabilizing the "Golf Ball on a Tee" 6:40 - The Athletic Accommodation Timeline: Why 6-9 Months Matters
8:36 - Progressive Overload for Connective Tissue, Not Just Muscle
11:36 - GLP-1s and Bone Health: Does Ozempic Increase Fracture Risk?
14:34 - Preventing Osteoporosis: The Power of Impact Training
18:15 - Bisphosphonates vs. Mechanical Loading for Bone Quality
21:10 - The Hidden History of Muscle: From Galen to Ancient Greece
26:48 - The Myth of "Pneuma" and the Soul in the Muscle
30:55 - Supercompensation: The "Gift from Zeus" in Performance
36:35 - Defining Impact Exercise: Why "Flight" is Better for Bones
39:48 - Building Your Base: Why Bone Health is Won Before Age 30
42:38 - Oral Contraceptives and Peroperative Blood Clot Risks
45:21 - The Hard Truth: How Nicotine Destroys Orthopedic Healing
47:55 - Testosterone and Muscle Mass vs. Bone Density in Women
51:41 - Relative Energy Deficiency in Sport (RED-s) and Stress Fractures
55:53 - Long-Term Menopause Consequences: Mobility and Hip Fractures
1:01:58 - Tendinopathy Treatments: Needle Tenotomy, 10X, and PRP
1:07:26 - Full Thickness vs. Incomplete Tendon Tears
1:12:05 - Prehab is Real: The Push-Up with a Plus and Skater Squats
1:13:58 - The Biomechanics of the Gate Cycle & Pelvic Stability
1:17:31 - Medications that Destroy Tendons: Fluoroquinolones & Statins
1:20:02 - Corticosteroids: Balancing Short-Term Relief with Repair Issues
1:24:12 - Nutrition for Joint Health: Collagen, Vitamin C, and Leucine
1:27:11 - Thyroid and Sex Hormone Influence on Tendon Metabolism 1:31:50 - The "Menopause Arthritis" Phenomenon
1:54:04 - Mobility vs. Stability: The 2x2 Evaluation Table
2:11:06 - Zone 2 vs. HIIT: Raising the Ceiling of Human Performance
2:24:21 - Anti-Fragility: Using Stressors to Get Stronger
Thank you to our sponsors:
- PaleoValley - Get 15% off automatically at https://paleovalley.com/DRLYONOneSkin - Get 15% off with the code DRLYON – https://www.oneskin.coBranch Basics -15% off and free shipping on the Starter Kit when you use code DRLYON at BranchBasics.com/DRLYONPIQUE - Get 20% off for life + a complimentary gift Piquelife.com/DRLYON
Find Dr. Jocelyn Wittstein at:
Duke Health - https://www.dukehealth.org/find-docto...
Instagram - @jocelyn_wittstein_md
The Complete Bone and Joint Health Plan - Find it at Amazon and Barnes & Noble
Find Gerard D'Onofrio, MD
Web: https://www.summithealth.com/doctors/provider/1376049130
LinkedIn: linkedin.com/in/gerarddonofrio27
Find Dr. Gabrielle Lyon at:
- Instagram:@drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 30 Dec 2025 - 2h 29min - 186 - Hormone Replacement Therapy Decoded: Why the FDA Removed the Blackbox Warning on HRT
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Find Dr. Gabrielle Lyon at:
- Instagram:@drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Timestamps:
0:00 - FDA Lifts Blackbox Warning on HRT
1:08 - Definitions: Viralization & Androgens
3:08 - The New Landscape of Women's Health
4:46 - Gold Standard Testing: Mass-Spec
5:52 - Finding the Estrogen Sweet Spot for Men
8:07 - Testosterone Lab Ranges for Women
10:16 - Is Testosterone Safe for Women?
13:30 - Anabolic vs. Androgenic Steroids
16:56 - HRT Red Flags: Who Should Not Start
18:19 - Longevity Benefits of HRT
21:23 - Estrogen's Role in Brain Health
24:32 - Performance Impact in Young Women
33:03 - Type 2 Muscle Hypertrophy
37:06 - Monitoring Hematocrit & Safety
41:44 - Delivery: Injections vs. Gels
42:31 - How TRT Can Mask Anemia
46:36 - Impact on Cholesterol & Lipids
51:48 - Non-Negotiable Baseline Lab Panels
53:23 - Case Study: 60-Year-Old Transformation
58:15 - The Future of FDA Approval
59:06 - Can DHEA Move the Needle?
Tue, 23 Dec 2025 - 1h 02min - 185 - Dr. Jen Ashton on Unimaginable Loss, Mental Health, and Post-Traumatic Growth
If you or someone you know is experiencing suicidal thoughts, emotional distress, or a mental health crisis, call or text 988, or chat via 988lifeline.org.
Support is available 24/7. You are not alone, and help is available.
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Dr. Gabrielle Lyon sits down with renowned medical correspondent and OB/GYN, Dr. Jen Ashton, for a profoundly personal and candid conversation about navigating life's most intense tragedies while maintaining a public career.
Dr. Ashton bravely opens up about the devastating suicide of her first husband, a world-class surgeon, 18 days after their divorce was finalized. She shares the raw reality of being in clinical shock and how the immense tragedy became an unexpected catalyst for post-traumatic growth.
Dr. Ashton, who holds a Master's degree in Nutritional Sciences, also brings her medical expertise to current health debates:
The Power of Fitness: Learn how resistance training became Dr. Ashton's lifeline to snap her out of emotional numbness and shock.The Hormone Misinformation Crisis: They discuss the flawed data and flawed media that led to 20 years of women being under-treated for menopause after the Women's Health Initiative (WHI).GLP-1 Myths: Dr. Ashton breaks down the top myths surrounding GLP-1 medications, the difference between absolute vs. relative risk, and the non-weight related benefits that are just beginning to emerge.The Problem with Extremes: They address the societal tendency to seek out quick-fix solutions in health, menopause, and obesity care, arguing that the true sweet spot is in a nuanced, moderate position.Finding Love Again: Dr. Ashton shares the unexpected miracle of finding profound love with her current husband, legendary sports executive and TV producer, Tom Werner.About Jen Ashton: Retiring stiff paper gowns and unrelatable medical advice, Dr. Jennifer Ashton, a Board-certified Ob-Gyn, author, and TV medical correspondent, breaks the barrier between doctor and patient. Affectionately referred to as your all-in-one ‘BFF’/Ob-Gyn, Dr. Jennifer Ashton marries an unparalleled medical background with an accessible‘girl’s-girl’ attitude. Though Dr. Ashton can easily speak to the latest beauty and fashion trends, this Ivy League graduate means business when it comes to women’s health.
Thank you to our sponsors:
Timeline - Get 20% off your order at https://timeline.com/LYON OneSkin - Get 15% off with the code DRLYON – https://www.oneskin.coFind Jen Ashton at:
Book: Life After Suicide - https://a.co/d/0HvOeSHIG: https://www.instagram.com/drjashtonWeb: https://www.joinajenda.comFind Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Timestamps:
0:00 - Intro: Tragedy and The Journey of Dr. Jen Ashton 2:05 - The Suicide of a Spouse: The Aftermath of Unimaginable Loss 4:26 - The Clinical Definition of Shock and Shattered Reality 5:10 - How Motherhood Becomes a Lifeline Through Trauma 6:32 - Writing the Book: The Obligation to Talk About Suicide 10:12 - Mental Health vs. Longevity: We Can’t Separate Mind and Body 11:40 - Social Media and the Real-Time Human Experiment on Mental Health 14:12 - The Anchor: How Fitness and Lifting Saved Dr. Ashton 16:29 - Post-Traumatic Growth: Her Children’s Incredible Wisdom 18:20 - Prioritizing Mental Health: The Checkup From the Neckup 19:18 - Suicide is a Disease: It's Not Something You Can "Think Your Way Out Of" 22:25 - Finding Love Again: The Miracle of Tom Werner 24:39 - Meeting Her Husband: A Harvard Grad and Titan in Sports/TV 28:13 - The Responsibility of a Public Figure to Be Transparent 30:04 - Transition to Correspondent: The Iron Man of Medical Communication 34:04 - Distilling Health Information: Why Credentials Matter 34:41 - The Economist Who Wrote a Pregnancy Book (Stay In Your Lane) 37:25 - The Humility of Science: We Must Be Prepared to Be Wrong 38:04 - The WHI Disaster: Flawed Data and Misrepresenting Menopause 40:08 - The Problem with Extremes: Why Moderation is Missing in Health 41:33 - The Narrative Risk: Why Telling Women They Are "Passive Victims" is Insulting 46:33 - Menopause Done Well: A Holistic Approach with Options 48:07 - Are Hormones Safe? Insights from a Practicing OB/GYN 51:08 - Non-Hormonal Options for Menopause Symptoms 53:27 - Favorite Hormone Delivery Method (Pill vs. Patch) 54:14 - GLP-1 Myths: Risk vs. Benefit and Thinking Like a Doctor 56:16 - Non-Weight Related Benefits of GLP-1s (Cognitive, Cardiac, Renal) 57:38 - Absolute vs. Relative Risk: The Math Behind Rare Side Effects 58:42 - Future of Obesity Management: Low-Dose GLP-1, HRT, and Anabolic Agents 1:00:15 - Maintenance Protocols: Why Physicians are DIYing Long-Term Care 1:00:54 - The Biggest GLP-1 Concern: Losing Too Much Muscle Mass 1:02:16 - The Hypothalamic Set Point: Why 90% of Diets Fail 1:06:39 - Society's Fat Shaming Bias: Obesity is a Chronic Disease 1:08:00 - Nutritional Gynecology: Connecting Food and Reproductive Stages 1:10:07 - Meeting the Four S’s: Safe, Simple, Sustainable, and Low Sugar 1:11:50 - Foundational Principles: Why Protein is Everything 1:14:35 - The Biggest Myth: Women Should Never Do Intermittent Fasting 1:16:26 - Hormesis and Adaptation: Applying Pressure to the System 1:17:33 - Resilience is a Practice: The Mental Framework for Internal Strength 1:20:57 - The Sisterhood of Women: Community is Crucial for Support 1:25:24 - Home Base: Tom Werner's Legacy of Helping Veterans
Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 16 Dec 2025 - 1h 27min - 184 - STOP Inflaming Your Body: The #1 Enemy to Egg Quality and Conception
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Dr. Gabrielle Lyon sits down with fertility specialist Dr. Natalie Crawford to tackle the urgent rise in infertility across both men and women. Dr. Crawford, an advocate for proactive reproductive health, reveals why inflammation is hijacking your fertility and why the old dogma that "age is the only factor" for egg quality is dangerously incomplete.
They cover critical, actionable steps—from the most important lifestyle changes you can make before IVF, to the toxic habits that are directly lowering sperm counts and causing miscarriages. Learn the three essential fertility awareness methods (FAMs) and what your doctor is missing when they check your thyroid.
Who is Natalie Crawford:
Natalie Crawford is a double board-certified fertility doctor with a nutrition background, here to help you understand your body and hormones, optimize your lifestyle, and take control of your reproductive future with confidence.
Thank you to our sponsors:
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Web: https://www.nataliecrawfordmd.com/https://www.youtube.com/c/NatalieCrawfordMD/videosPODCASThttps://www.nataliecrawfordmd.com/blog-1Find Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Timestamps:
0:00 - Inflammation is Hijacking Your Fertility
2:00 - The Infertility Crisis: 1 in 5 Couples Struggle
3:41 - Male vs. Female: Who is Becoming More Infertile?
4:03 - Sperm Counts Down 50% & The Rise of Premature Menopause
4:57 - The #1 Cause of Infertility: Chronic Inflammation
6:08 - Egg Quality: You CAN Influence Your Mitochondrial Health
8:18 - The 5 Pillars of Fertility: Sleep, Stress, Muscle, Diet, Toxins
8:53 - The Foundation: Why Sleep is Non-Negotiable for Hormones
11:13 - Fertility is a Team Sport: Why Sleep Impacts Men More Quickly
12:55 - How Much Sleep Do You Need? (Circadian Rhythm is Crucial)
15:19 - Supplements and Herbs: The Danger of Chaste Tree Berry (Vitex)
18:38 - The Problem with Glandular & Adrenal Support Supplements
22:31 - Alcohol and Cannabis: Why They are Profoundly Inflammatory
24:49 - Miscarriage Risk: Male Cannabis Use & Uterine Septum
25:57 - Autoimmune Disease: Celiac, Thyroid, and Miscarriage
28:03 - Celiac Disease: Treating the Root Cause of Inflammation
29:32 - The Fellow's Journey: Why Dr. Crawford Studied Natural Fertility
33:24 - The 12-Month Prep Plan: Screening for Autoimmunity (Thyroid/Celiac)
34:07 - Hashimoto's & Thyroid: Why Your TSH Range is Misleading
37:34 - Period Problems: When a "Regular" Cycle Isn't Ovulating Optimally
40:27 - Thyroid Treatment: Synthetic vs. Animal-Derived Hormones
44:09 - Environmental Toxins: Their Huge Role in Fertility & Ovarian Reserve
46:09 - Where to Start: Water, Air Filters, and Non-Teflon Cookware
48:54 - Toxins: Stainless Steel, Glass, and Avoiding Hot Plastic
50:45 - Processed Foods and Takeout: The Danger of Packaging
54:24 - Sex for Conception: How Much is Enough? (No Need to Abstain)
56:41 - Use It or Lose It: Why the Vagina Can Atrophy
57:56 - The 3 Fertility Awareness Methods (FAMs) to Track Ovulation
1:00:59 - Basil Body Temperature & Wearable Tech for Ovulation
Tue, 09 Dec 2025 - 1h 02min - 183 - Carbs vs. Protein: Which Macronutrient Is Actually More Dangerous to Overconsume?
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Dr. Gabrielle Lyon reveals the biggest mistakes Americans make with their nutrition and body composition, especially after age 40. With 75% of Americans overweight or obese, the problem is clear: excess calories from cheap, processed carbohydrates.
Dr. Lyon dissects the metabolic science, explaining why skeletal muscle—the largest organ—is not designed to dispose of the massive carb loads found in the average American diet. Learn the essential strategies, including the 1:1 Protein-to-Carbohydrate Ratio Rule and the importance of Carbohydrate Tolerance, to design a meal plan that maximizes muscle, controls insulin, and guarantees success.
Nick Barringer is an expert on nutrition and performance for the tactical athlete. Nick Barringer currently serves as the Program Director for the Army-Baylor University Master’s Program in Nutrition. Barringer has a Doctorate degree in Kinesiology from Texas A&M University and received his undergraduate degree in dietetics from the University of Georgia. Barringer previously served as an assistant professor at the United States Military Academy at West Point and as the Regimental Nutritionist and as a member of the Ranger Athlete Warrior (RAW) program at the 75th Ranger Regiment. Nick has gone through physically demanding courses such as Ranger School, Survival Evasion Resistance Escape(SERE), Airborne, Air Assault as well as having deployed to both Iraq and Afghanistan.
Thank you to our sponsors:
BodyHealth - Use the code LYON 20 to get 20% off your first order bodyhealth.com
PIQUE - Get 20% off for life + a complimentary gift Piquelife.com/DRLYON
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OneSkin - Get 15% off with the code DRLYON – https://www.oneskin.co
Find Nick at:
https://www.instagram.com/nickbarringer.phd.rdnhttps://drnickbarringer.com/Find Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimers: This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 02 Dec 2025 - 54min - 182 - Over 70 and Shredded: The Guide to Building Muscle at Any Age | Michelle & Joan MacDonald
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In this empowering episode, Dr. Gabrielle Lyon sits down with the incredible mother-daughter duo, Michelle and Joan MacDonald, to share the blueprint for radical physical transformation at any age. Joan, who began her journey nearing 71 years old, proves it's never too late, while coach Michelle, a Certified Strength and Conditioning Specialist (CSCS), cuts through the noise on training, nutrition, and mindset.
They tackle deeply personal topics, including Michelle's 15-year struggle with a severe eating disorder and the shame that surrounds women's health. This is a must-watch to learn the non-negotiable pillars for building a strong, resilient, and healthy body, no matter your starting point.
Michelle MacDonald is a trailblazer in the global movement to redefine aging and female
empowerment through strength. As the founder of The Wonderwomen, a world-class coaching
brand built on her signature methodology, The Fitness Model Blueprint™, Michelle has
transformed thousands of women—inside and out—with evidence-based strategies that merge
mindset, muscle, and metabolic mastery.
Joan MacDonald (Fitness Icon and Mother)
At 70, Joan MacDonald was getting winded walking up a flight of stairs and now, at 74, she is doing weighted pull-ups and 200 lb hip thrusts.
This episode is sponsored by:
- Branch Basics - 15% off and free shipping on the Starter Kit when you use code DRLYON at BranchBasics.com/DRLYON
- BON CHARGE Holiday Sale https://boncharge.com for 25% off
- Manukora - BLACK FRIDAY SALE: Save $151 on Manukora Starter Kit MANUKORA.com/DRLYON
Chapters:
0:00 - The ED Crisis: Michelle’s 15-Year Battle & Recovery
2:04 - Joan Started Lifting at 71: Debunking the Age Myth
6:16 - Pillars of Transformation: Mindset, Sleep, Food
8:52 - Finding Your "Why": Aesthetics vs. Longevity
12:01 - Why Strength Training Must Come First
14:28 - Grittiness: The Secret to Joan's Radical Success
24:54 - Hard Truths: The "Nursing Home" Speech That Changed Joan's Life
26:47 - The Transformation Container: Non-Negotiables for Success
47:03 - Disordered Eating: When to Get Expert Therapy vs. Coaching
50:11 - GLP-1s and the "Food Noise" Solution
58:12 - 3 Essential Beginner Exercises (Joan's Choices)
1:04:22 - Strength Goals: The 3 Exercises a Strong 40-Year-Old Must Master
1:10:29 - The Hip Thrust: #1 Glute Builder and Muscle Mandate
1:14:09 - Training is a Skill: How to Prevent Injury
1:19:11 - Core Strength: Why Glutes and Abs Prevent Falls
1:33:37 - Training the Individual: Why Age Doesn't Matter
1:37:29 - Nutrition Blueprint: Protein First for Satiety and Adherence
Find Michelle at:
https://www.instagram.com/yourhealthyhedonista/
http://MichelleMacdonaldOfficial.com
Podcast: https://podcasts.apple.com/us/podcast/the-wonder-women-official/id1677831398
Find Joan at:
https://www.instagram.com/trainwithjoan
https://www.trainwithjoanofficial.com
Find Dr. Gabrielle Lyon at:
- Instagram:@drgabriellelyon
- TikTok: @drgabriellelyon
- Facebook: facebook.com/doctorgabriellelyon
- YouTube: youtube.com/@DrGabrielleLyon
- X (Twitter): x.com/drgabriellelyon
- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
- Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 25 Nov 2025 - 1h 43min - 181 - TRT: Your Complete Guide to Safe Dosing, Risks, and Boosting Longevity
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In this compilation episode, Dr. Gabrielle Lyon is joined by the top experts in Testosterone and men's health treatments.
You'll learn:
Why aging alone doesn't drop T levels and why acquisition of conditions like obesity is the real culprit.Why the standard "low T" cutoff is misleading and why you must check your Free Testosterone.How erectile dysfunction is a sensitive marker of overall health and heart risk.The efficacy of Cialis/Viagra for both erections and cardiac protection, and the risks of unchecked influencer advice on steroids.The direct link between muscle mass, exercise, and sexual function—and why the penis is the "first to go" when overall health declines.Chapter Markers:
0:00 - Testosterone is a Brain Hormone
0:40 - Debunking the Myth: Male Menopause (Andropause) Doesn't Exist
1:33 - The Dangers of Unchecked Influencer Advice on Testosterone
3:07 - Defining Testosterone Deficiency: Symptoms vs. Signs
5:10 - The Arbitrary Number: Why Guidelines Disagree on Low T
8:29 - Free Testosterone: The Most Reliable Indicator of Male Health
15:28 - TRT vs. Steroids: Defining the Line and Risks
18:59 - The Real Risks of TRT: Infertility and Hematocrit
22:36 - The Shocking Backstory: Challenging the Prostate Cancer Myth
26:40 - Erectile Dysfunction (ED) and Lifestyle Modification
29:21 - Shockwave Therapy for ED: The Science and the Cash Business
33:53 - Penile Tissue Atrophy and Venous Leak
37:25 - The Role of Muscle Mass, Sarcopenia, and Sexual Function
39:41 - The Single Best Marker for Male Health: Erectile Function
42:02 - The Science of Cialis and Viagra (PDE5 Inhibitors)
45:49 - The Viagra Story: From Heart Drug to ED Cure
50:50 - Tadalafil (Cialis) as a Triple-Threat Drug (Cardiac, Urinary, Sexual)
53:57 - The Role of Testosterone in Female Sexual Function
55:20 - Hypogonadism: Diagnosis, Treatment, and Fertility Risk
About the guests:
Dr. Abraham Morgentaler is an Associate Clinical Professor of Urology at Harvard Medical School and founder of Men's Health Boston. He is an internationally recognized expert in men's health, particularly known for his pioneering work in testosterone therapy. Dr. Morgentaler is credited with reversing the long-held belief that testosterone therapy causes prostate cancer and is the author of several books on men's health.
YouTubeLinkedInT4L EducationX/TwitterDr. Tobias Kohler is the co-founder of the Erectile Restoration Outcomes Study (EROS) penile implant registry. In addition to his clinical and research activities, Dr. Kohler is active in education, providing mentorship to residents and fellows.
Mayo ClinicResearchGateLinkedInX(Twitter)Dr. Mohit Khera, M.D., M.B.A., M.P.H., is a urologist and professor at Baylor College of Medicine. He is an expert in male and female sexual dysfunction and testosterone replacement therapy, and his work focuses on male infertility, sexual dysfunction, and declining testosterone levels. He is also the President of the Sexual Medicine Society of North America.
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The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
This episode includes paid sponsorships.
Tue, 18 Nov 2025 - 1h 39min - 180 - Neuroscientist Explains MDMA and The Science of Social Connection | Dr. Ben Rein Ph.D.
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In this fascinating episode, Dr. Gabrielle Lyon talks with neuroscientist Dr. Ben Rein, PhD (author of Why Brains Need Friends), about the science of social connection, emotion, and cognitive health. Dr. Rein, an expert in neurobiology and psychedelic research, reveals the cutting-edge studies that explain why loneliness is as damaging as smoking and how our digital world is affecting our brain's ability to connect.
They discuss the neurochemistry of love, the controversial use of MDMA in therapy, and whether AI can ever truly replace human intimacy. This conversation provides an essential look at the biological drivers of happiness, performance, and long-term brain health.
Chapter Markers:
0:00 - MDMA (Molly): The History & Therapeutic Benefits
5:59 - The Legal Status of MDMA for PTSD
6:44 - The Safety and Effectiveness of MDMA in Clinical Trials
8:29 - PTSD (The Amygdala Alarm)
9:41 - How MDMA Soothes the Amygdala to Access Memory
11:42 - Is There an Alternative to MDMA? (Ketamine's Mechanism)
13:16 - Ketamine and Neuroplasticity for Depression
15:48 - Botox and Empathy:
18:12 - The Problem of Volume: How Screens Depersonalize Interaction
19:48 - The Virtual Disengagement Hypothesis Explained
25:00 - Defining Cognitive and Emotional Empathy
29:43 - MDMA's Link to Serotonin & Social Reward
31:04 - Do SSRIs Have Pro-Social Effects?
36:10 - The Science of Likability and "Easy to Read" Faces
40:10 - Top 3 Ways to Be More Likable
49:49 - The Likability Gap: Why You Underestimate How Well-Liked You Are
56:59 - The Neurobiology of Oxytocin, Dopamine, and Serotonin
1:09:23 - The Goldilocks Zone of Empathy
1:15:58 - Narcolepsy
1:18:16 - Alcohol: Why the Neurotoxin is Bad for Brain Health
1:21:47 - Exercise and Neurogenesis
1:22:27 - Sex, Orgasm, and Oxytocin Release
1:25:06 - Oxytocin During Childbirth
Who is Ben Rein:
Dr. Ben Rein is an award-winning neuroscientist and Chief Science Officer of the Mind Science Foundation, where he supports early-career researchers in neuroscience. He earned his PhD from SUNY Buffalo and completed postdoctoral training at Stanford University, publishing over 20 peer-reviewed papers on autism, empathy, MDMA, and digital behavior. Recognized by the NIH, the Society for Neuroscience, and Sigma Xi, he also serves as a scientific advisor to more than 20 organizations. With over one million followers and 75 million video views, Dr. Rein is celebrated for making neuroscience accessible to the public and has been featured by outlets such as Good Morning America, ABC News, and PopularMechanics.
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Find Ben Rein at:
Website: https://www.benrein.com/Instagram: https://www.instagram.com/dr.benrein/#TikTok: https://www.tiktok.com/@dr.benrein?lang=enFacebook: https://www.facebook.com/benreinneuroscience/Youtube: @dr.benreinFind Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimers:
This episode includes paid sponsorships.
The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 11 Nov 2025 - 1h 27min - 179 - Sex Therapist explains The Science-Backed Guide to a Better Sex Life | Marianne Brandon
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In this explosive episode, Dr. Gabrielle Lyon sits down with relationship expert Marianne Brandon to confront the modern crisis of intimacy and sexual wellness. They dive into how the digital world—including porn, AI companions, and VR technology—is creating an evolutionary mismatch that clashes with our primal needs for bonding, leading to rising loneliness and sexual dysfunction.
Dr. Lyon and Marianne Brandon explore the science behind what truly impacts performance, from erectile dysfunction (ED) and hormonal imbalances to the neurological effects of stress. This is a must-watch for couples, parents, and anyone navigating romance in the digital age.
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Chapter Markers
0:00 - Intro
0:49 - The Primal Need for Sex vs. The Digital World
1:10 - The Hidden Cause of Erectile Dysfunction (ED)
2:10 - The Loneliness Crisis: Gen Z, AI, and Intimacy
3:50 - Do Women and Men Experience Desire Differently?
5:15 - Stress is the #1 Libido Killer
6:30 - Porn and AI: Is Sexting with a Bot Cheating?
8:05 - The Surprising Impact of VR Porn on Sperm Quality
9:30 - Action Plan: The #1 Move to Improve Your Sex Life Today
Who is Marianne Brandon:
Dr. Marianne Brandon is a licensed clinical psychologist and a diplomate in sex therapy, recognized for her expertise in technologies impact on intimacy, evolutionary influences on human sexuality, and cultivating a more exciting sexual connection in long-term relationships. Dr. Brandon is best known for her forward-thinking work on the future of intimacy through blogging, lecturing, and podcasting. Her popular Psychology Today blog, “The Future of Intimacy,” explores emerging trends in technology and human connection. As a continuing education provider, she lectures on sex tech’s impact on intimacy as well as the impact of technology on humanity. Together with her husband, urologist Dr. Abraham Morgentaler, she co-hosts the podcast “The Sex Doctors,” bringing expert insight and candid dialogue to listeners on all aspects of sex, relationships, and technology’s transformative role in our lives. Drawing from nearly three decades of clinical experience, she offers psychotherapy focused on relationship issues and sexual concerns, with a reputation for blending clinical skill and compassionate care.
This episode is brought to you by:
BodyHealth - Get 20% off your first order with code LYON20 - https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/Timeline - Get 20% off your order - https://timeline.com/LYONOneSkin - Get 15% off with the code DRLYON – https://www.oneskin.coFind Marianne Brandon at:
Website: https://www.drbrandon.net/LinkedIn: https://www.linkedin.com/in/mariannebrandon-59224513X: https://x.com/drbrandonFind Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 04 Nov 2025 - 1h 19min - 178 - The Menstrual Cycle DECODED: Fertility, PCOS, and the New Science of Hormones
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In this episode, Dr. Gabrielle Lyon sits down with Dr. Heidi van den Brink; one of the only scientists in the world studying the ovarian transition from fertility to menopause. Together, they unpack what textbooks and wellness influencers often miss: the biology behind how your ovaries, uterus, metabolism, and nutrition interact across every stage of a woman’s life.
Dr. Heidi reveals the never-before-seen dynamics of the ovarian cycle, how follicles develop in “waves,” and what really happens during the menopause transition. They discuss how undernutrition, obesity, and metabolic health shape reproductive hormones; why early menarche and delayed ovulation matter for long-term health; and the surprising connection between your gut microbiome, bile acids, and fertility.
If you’ve ever been told to “balance your hormones” with seed cycling, apps, or supplements, this episode separates myths from mechanisms. It’s a masterclass in understanding the science of your hormones and how to truly support reproductive health through every decade of life.
Chapter Markers
0:00 - Can You Get Pregnant While on Your Period?
1:21 - Intro to Dr. Heidi & Ovarian Cycle Research
3:39 - The Uterine Cycle vs. The Ovarian Cycle
6:19 - Follicle Waves: The Hidden Drama in Your Ovaries
10:38 - Novel Discovery: Follicle Waves in the Luteal Phase
12:00 - Why One Follicle is Selected for Ovulation
13:17 - Does Nutrition Affect Ovarian Function?
14:48 - The Variation in Menstrual Cycles (It's Not Always 28 Days)
17:23 - The Impact of Obesity on the Ovarian Cycle
18:11 - The Problem of Luteal Phase Defects & Fertility
24:52 - Ovarian Morphology as a Bio-Marker of Health
26:54 - How Undernutrition Affects Ovarian Health
31:56 - The Metabolic Tipping Point of PCOS (Polycystic Ovary Syndrome)
33:26 - The Myth of the "String of Pearls" Ovary
35:25 - The Menopause Transition & Rogue Follicles
39:04 - Can We Predict Menopause by Scanning Ovaries?
45:59 - Early Menarche (First Period) and Long-Term Disease Risk
48:33 - The Surprising Link Between Puberty Timing and Environment
52:28 - The Role of Leptin in Reproductive Health
55:50 - Debunking the Myth: Can Nutrition Cure PCOS?
59:07 - PCOS Diet Myths (Fruit, Timing, and Supplements)
1:04:40 - Fish Oil for Menstrual Cramps (Dysmenorrhea)
1:08:37 - Breakthrough: Bile Acid, The Gut Microbiome, and Ovulation
1:11:50 - Closing Remarks
Who is Heidi Vanden Brink:
Dr. Vanden Brink is a reproductive physiologist with over a decade of research in nutrition, metabolism, and female reproductive health. Her work focuses on how diet and metabolic conditions like obesity influence reproductive development during adolescence, with the goal of preventing disorders such as PCOS.
Find Heidi Vanden Brink at:
Texas A&M University: https://nutrition.tamu.edu/people/vanden-brink-heidi/ Google Scholar: https://scholar.google.com/citations?user=ZzOJRY0AAAAJ&hl=enFind Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623This episode is brought to you by:
BON CHARGE - Use code DRLYON to get 15% off your entire order - https://boncharge.com/DRLYON Timeline - Get 20% off your order at https://timeline.com/LYONDisclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 28 Oct 2025 - 1h 12min - 177 - TRT Risks & Rewards: Your Testosterone Replacement Therapy Questions Answered
In this highly requested AMA, Dr. Gabrielle Lyon addresses the most critical questions surrounding male hormone health. Dr. Lyon tackles the fear, stigma, and misinformation surrounding Testosterone Replacement Therapy (TRT), revealing why a low testosterone level is a major predictor of serious health issues like heart disease, bone fracture, and obesity.
She breaks down the current medical consensus on TRT, the risks of replacement, the truth about dosing, and what every man over 40 needs to know about their hormone health. This is a must-watch to separate the bodybuilding myths from the medical facts.
Chapter Markers
0:00 - Intro: Low Testosterone is a Predictor of Heart Disease
1:12 - The Penile Shrinking Myth: What Caused the Viral Frenzy
2:20 - Testosterone Levels: The Truth About Aging in Men
3:44 - The First Step: What Labs to Ask Your Doctor for
4:22 - Why Men Need to Check Their Estrogen (Estradiol)
6:13 - The Medical Cutoff for Low T and Androgen Sensitivity
7:27 - Low T is Linked to Fatigue, Depression, and Fat Deposition
9:27 - TRT and Cardiovascular Health: Is it Protective or a Risk?
10:36 - Erectile Dysfunction Predicts Heart Attack Within 3-5 Years
12:30 - The Stigma: Why Doctors Don't Check Testosterone
13:00 - TRT vs. Steroids: Defining the Line
14:21 - Infertility and TRT: What You Must Know
15:18 - Safety: What are the Risks of TRT for Men?
16:33 - The Stigma: Why Doctors Don't Treat Low T
17:15 - TRT and Obesity: Treat Concurrently or Wait?
18:10 - Menopause vs. Andropause: Why Men Don't Have to Decline
19:34 - Testosterone Boosters (Ashwagandha, Tongkat Ali)
26:11 - Different Forms of Testosterone Administration
28:09 - Intranasal Testosterone for Less Impact on Fertility
30:38 - Managing Expectations: How Long Until You Feel Better?
33:00 - TRT and Muscle Gain: The Highs and Lows of Dosing
36:47 - The Win-Win: Low Risk, High Reward
39:00 - Blood Flow & Erectile Function: Cialis and Exercise
40:17 - Semen Quality as a Marker for Overall Male Health
41:29 - Parenting and the Cost of Unhealthy Humans
41:45 - How to Raise Testosterone Naturally (The Pillars)
42:29 - Low-Dose Cialis for Cardiovascular Health (Preemptive Strategy)
43:59 - Dr. Lyon's TRT Journey and Early Concerns
46:00 - Outro
Key Takeaways:
Low Testosterone is a major health risk. Low T is linked to an increased risk of bone fracture, heart disease, obesity, and diabetes.TRT is often protective. Contrary to the long-standing myth, replacing low testosterone to a healthy range does not increase the risk of cardiac events. It is, in fact, protective against cardiovascular disease.Erectile Dysfunction (ED) is a canary in the coal mine. ED can predict a heart attack within 3 to 5 years.Men can maintain high T levels. Testosterone levels in a healthy 75-year-old can be just as good as in a man in his 20s.The solution is often concurrent. For an obese or overweight man with low T, concurrent treatment with TRT and a lifestyle intervention is often the most responsible approach to provide the motivation needed for weight loss.Low-dose daily Cialis (2.5mg to 5mg) may be a viable preemptive strategy for cardiovascular health due to its blood flow benefits.This episode is brought to you by:
Manukora - Get $25 off your Starter Kit at https://manukora.com/DRLYON Our Place - Use Code DRLYON for 10% off sitewide at https://fromourplace.com/DRLYONFind Nick Barringer PhD at:
https://drnickbarringer.com/ https://www.instagram.com/nickbarringer.phd.rdnFind Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 21 Oct 2025 - 44min - 176 - The Cancer Scare That Taught Jeremy Miner What Really Matters
In this powerful episode, Dr. Gabrielle Lyon sits down with legendary sales expert and entrepreneur Jeremy Miner to discuss the foundation of success. Jeremy, the founder of Seventh Level, reveals the mental frameworks, communication skills, and commitment required to achieve peak performance in any area of life.
Drawing from his own harrowing health scare and decades of experience coaching top performers, Jeremy shares candid insights into what separates the top 1% from everyone else. This conversation is not just about sales—it’s about the psychology of human connection, overcoming fear, and unlocking your full potential to build a more resilient and successful life.
Who is Jeremy Miner:
Jeremy Miner is an internationally recognized sales trainer and entrepreneur, best known as the founder of the sales training company 7th Level. He is the creator of the Neuro-Persuasion Sales Method and has a background in behavioral science, which he uses to train sales professionals. Previously, he was a highly successful, commission-only salesperson who was ranked among the top earners globally before retiring to start his training company.
Timestamps:
0:00 - Intro
3:06 - The Psychology of Success
10:31 - How Fear Can Drive You
14:40 - Communication Skills
33:14 - The Power of Problem-Finding
39:33 - The 4 Categories of Performance
1:00:21 - Jeremy’s Cancer Scare
1:12:32 - Advice for Mental Toughness
This episode is brought to you by:
Puori - Use code DRLYON for 20% off - https://puori.com/DRLYONCozy Earth - Use code DRLYON for up to 20% off - cozyearth.com/DRLYONBON CHARGE - Use code DRLYON to get 15% off your entire order - https://boncharge.com/DRLYONOneSkin - Get 15% off with the code DRLYON – https://www.oneskin.coFind Jeremy Miner at:
Tiktok: https://www.tiktok.com/@jeremy_miner)Instagram: https://www.instagram.com/jeremyleeminer/)Facebook: https://www.facebook.com/JeremyLeeMiner/Offers:
7q.ai (http://7q.ai/) Waitlist: https://7q.ai/waitlistThe NEPQ PRIMER Community: https://nepqtraining.com/primer?utm_campaign=nepq-primer&utm_content=Instagram-&utm_medium=organic&utm_source=InstagramJoin the Salesteam: https://hardlyselling.hirebus-careers.com/closer-7th-level
Find Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 14 Oct 2025 - 1h 13min - 175 - The Future of Prostate Cancer Treatments & Non-Invasive Techniques with Less Side Effects | Dr. Sanjay Mehta
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When you hear the word “radiation,” do you think of cancer, Chernobyl, or an airport scanner? In this powerful episode, Dr. Gabrielle Lyon sits down with Dr. Sanjay Mehta, a radiation oncologist, to completely redefine your understanding of radiation as a tool for medicine.
Dr. Mehta reveals how modern technology has made radiation oncology incredibly precise, minimizing side effects for cancer patients. He also shares groundbreaking insights into the underutilized field of low-dose radiation therapy, a safe and effective treatment for common inflammatory conditions like arthritis, tendinitis, and plantar fasciitis. This conversation is a must-watch for anyone with chronic pain or a fear of radiation, offering a new path to health and healing.
Chapter Markers
0:00 - Intro
0:42 - The biggest myths about radiation
1:33 - Dr. Sanjay Mheta's introduction
2:07 - Radiation as a treatment for prostate cancer
3:41 - The side effects of surgery vs. radiation
4:32 - The training of a radiation oncologist
5:34 - Full-body scans and diagnosis
7:48 - What is radiation?
9:00 - The difference between medicine and poison
10:50 - The electromagnetic spectrum
12:21 - Ionizing vs. Non-ionizing radiation
13:42 - How we are naturally exposed to radiation
15:50 - The biggest myth about radiation
18:50 - Hormesis and low-dose radiation
21:10 - The evolution of radiation technology
22:38 - Radiation in daily life (dentist X-rays)
25:00 - Can all cancers be destroyed by radiation?
26:43 - Why radiation doesn't always burn skin
28:25 - How radiation treatment is planned
32:27 - Side effects of prostate cancer surgery
33:09 - Penile shortening and prostate surgery
36:00 - The role of testosterone in prostate cancer
38:37 - How radiation affects bodybuilders
39:09 - Who is not a candidate for radiation?
41:33 - Is radiation the standard of care for all cancers?
42:32 - Debunking radiation fear (microwaves, etc.)
44:38 - The airport scanner debate
47:03 - Other sources of radiation exposure
52:32 - Grounding and radiation
54:40 - Low-dose radiation for musculoskeletal injuries
55:50 - The history of low-dose radiation
57:22 - The use of radiation in the 1800s
59:42 - Cortisone vs. low-dose radiation for pain
1:03:00 - Dr. Ma's personal story of treatment
1:04:07 - The duration and protocol of low-dose radiation
1:08:16 - Inflammation and low-dose radiation
1:10:59 - The durability of radiation therapy
1:12:00 - Reversal of disease
1:17:22 - Radiation's effect on hip pain
1:18:29 - Treating rheumatoid arthritis
1:20:29 - Post-operative radiation
1:22:11 - Low-dose radiation for Peyronie's disease
1:24:42 - What's holding back adoption of this therapy in the US?
1:26:45 - The future of low-dose radiation
1:27:31 - How to book an appointment with Dr. Mehta
1:28:09 - Closing Remarks
Who is Dr. Sanjay Mehta?
Dr. Sanjay Mehta has been treating cancer patients for over 25 years using state of the art radiation oncology technology. He is now successfully treating patients with arthritis, tendonitis, and plantar fasciitis with low dose radiation using proven European regimens. It is non invasive, painless, and covered by Medicare and most insurance plans.
This episode is brought to you by:
PaleoValley - Get 15% off automatically at https://paleovalley.com/DRLYONTimeline - Get 20% off your order at https://timeline.com/LYON Needed - Use code DRLYON for 20% off your first order at https://thisisneeded.com LMNT - Free sample pack with any purchase at https://drinklmnt.com/DRLYONFind Dr. Sanjay Mehta at:
Web: https://drsanjaymehta.comFacebook: https://www.facebook.com/profile.php?id=100066466934049Find Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 07 Oct 2025 - 1h 28min - 174 - A Parent's Guide to Vaccines & Obesity: Protecting Your Child in a Confusing World | Dr. Joel Gator
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Description
In this episode, Dr. Gabrielle Lyon sits down with pediatrician Dr. Joel Gator Warsh to confront the most concerning trends in children's health. Dr. Warsh, author of A Shot and a Hard Place, reveals the staggering rise of chronic disease and autism in children, arguing that it's a crisis that demands a deeper, more open conversation.
This is a brave and necessary discussion that moves beyond political rhetoric and into the science. Dr. Warsh, an epidemiologist, offers a candid perspective on the vaccine debate, challenging the notion that the "science is settled." He reveals the surprising truth about what research has and hasn't been done on the long-term effects of the cumulative vaccine schedule.
This episode is a must-listen for any parent who wants to be empowered with the knowledge to make informed decisions for their family and understand the true impact of our food system, environmental exposures, and sedentary lifestyles on the next generation.
Chapter Markers:
0:00 - The Chronic Disease Epidemic in Kids
2:51 - The Vaccine Debate: Risks vs. Benefits
4:06 - A Pediatrician's Take on the Newborn Hep B Vaccine
12:50 - The Alarming Rise in Autism Rates
15:09 - The Missing Research on the Vaccine Schedule
19:30 - How to Navigate Conflicting Information from RFK Jr.
40:01 - The Role of Environmental Toxins in Chronic Illness
44:50 - The Food System & The Epidemic of Childhood Obesity
50:11 - Screen Time & The Sedentary Child
55:50 - The Presidential Fitness Test Debate
1:00:03 - Safe Workouts for Kids & The Importance of Movement
1:11:31 - Final Thoughts on CDC, Personal Choice & The Road Ahead
Who is Joel Gator Warsh:
Joel Gator Warsh is a Board-Certified Pediatrician in Los Angeles, California who specializes in Parenting, Wellness and Integrative Medicine. He grew up in Toronto, Canada and completed degrees in Kinesiology, Psychology and Epidemiology and Community Health before earning his medical degree from Thomas Jefferson Medical College. He completed his Pediatric Medicine training at Children’s Hospital of Los Angeles (CHLA) and worked in private practice in Beverly Hills before founding his current practice, Integrative Pediatrics and Medicine Studio City, in 2018. Dr. Gator has published research in peer-reviewed journals on topics including childhood injuries, obesity and physical activity. He has been featured in numerous documentaries, films, summits, podcasts and articles including CBS, Fox, LA Parent, Washington Post, MindBodyGreen, and many others. He is also the founder of the Parenting Masterclass Platform Raising Amazing which can be found at RaisingAmazingPlus.com. Dr. Joel Gator may be best known for his popular Instagram DrJoelGator where he offers weekly parenting and integrative pediatric support.
This episode is brought to you by:
Timeline - Get 20% off your order at https://timeline.com/LYONOneSkin - Get 15% off with the code DRLYON – https://www.oneskin.coLMNT - Free sample pack with any purchase at https://drinklmnt.com/DRLYONPuori - Use code DRLYON for 20% off - https://puori.com/DRLYONFind Joel Gator at:
Instagram: https://instagram.com/drjoelgator/Website: https://www.raisingamazingplus.com/Find Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 30 Sep 2025 - 1h 24min - 173 - The TRUTH About Makeup, Sunscreen and Skin Cancer | Teo Soleymani
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In this episode, Dr. Gabrielle Lyon sits down with Dr. Teo Soleymani, a fellowship-trained skin cancer surgeon and dermatologist, to cut through the noise of the skincare industry. They discuss everything from viral trends like "glass skin" to the science behind hormones, sun protection, and the lifestyle factors that truly determine your skin's health and longevity.
Dr. Teo Soleymani debunks common myths and provides actionable, no-nonsense advice on what to use—and what to avoid—to build a powerful, evidence-based skincare regimen. This conversation is a must-watch for anyone who wants to stop guessing about their skin and start seeing real results.
Join the Forever Strong Menopause Challenge today and get your 4-week, science-based plan to build strength, improve sleep, and feel in control again: https://drgabriellelyon.com/forever-strong-menopause-challenge/
Chapters:
0:00 - Intro: K-Beauty, Multi-Step Routines & The Makeup Debate
6:15 - The Dangers of Makeup & Environmental Toxins
11:50 - The Shocking Effects of Hormones on Skin & Hair
16:59 - How Testosterone & Estrogen Impact Your Skin
22:58 - The Best Way to Use Hormones for Skin Health
29:20 - The Rise of Social Media Doctors & Medical Misinformation
33:24 - The TRUTH About Sun Exposure, Skin Cancer & Aging
46:00 - The Crucial Role of Diet & Protein in Skin Health
48:13 - Oral Collagen, Vitamin C & Skin Hydration
54:12 - Treating Crepey Skin with Lasers & Topicals
1:02:47 - Dr. Solommani's Perfect Anti-Aging Regimen
1:14:03 - The Beef Tallow Debate & How to Choose a Moisturizer
1:16:53 - Red Light Therapy for Skin & Hair Growth
1:21:26 - The Truth About Minoxidil, PRP & Exosomes
1:28:40 - The Best Oral Supplements for Internal Sun Protection
1:34:01 - Sun Powder: An Internal Sunscreen
1:40:56 - Final Thoughts & The Future of Skincare
Who is Dr Soleymani:
A Los Angeles native, Dr. Soleymani completed his undergraduate studies in Evolutionary Biology at UCLA. He went on to graduate from the University of California, Irvine School of Medicine, during which time he was awarded numerous accolades for academic excellence and was inducted into the prestigious Alpha Omega Alpha honor society, considered widely to be the highest award bestowed in medical school. Dr.Soleymani completed his internship at Cedars-Sinai Medical Center, where he was awarded the UCLA David Geffen School of Medicine Excellence in Teaching with Humanism Award. He then went on to complete his residency at Stanford University in Palo Alto, California, one of the world’s most premier dermatology training programs. While at Stanford, Dr. Soleymani worked with world-renowned experts in cutaneous oncology and complex skin diseases and was the recipient of various academic awards and distinctions.
This episode is brought to you by:
Puori - Use code DRLYON for 20% off - https://puori.com/DRLYONARMRA - Use code DRLYON to get 15% off your first order - https://tryarmra.com/DRLYONBON CHARGE - Use code DRLYON to get 15% off your entire order - https://boncharge.com/DRLYONManukora - Get $25 off your Starter Kit at https://manukora.com/DRLYONFind Dr Soleymani at:
Instagram: https://www.instagram.com/teosoleymanimdWebsite: https://www.californiadermatology.com/provider/teo-soleymani-md-faad-facmsFind Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://drgabriellelyon.com/sign-up/Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 23 Sep 2025 - 1h 41min - 172 - Why Navy SEALs Aren't Scared Like Everyone Else | Rich Diviney
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In this powerful episode, Dr. Gabrielle Lyon sits down with former Navy SEAL Commander and author, Rich Diviney, to break down what it takes to thrive under extreme pressure. Rich, author of "The Attributes and Mastering Uncertainty", reveals the psychology of elite performance, explaining why true toughness has less to do with physical strength and more to do with your mental attributes.
He shares candid insights into the realities of SEAL training, the mental tools used in combat, and why the "little tragedies" of everyday life are your training ground for resilience. This is a must-watch for anyone who wants to build the mental fortitude to overcome anxiety, step outside their comfort zone, and reach their full potential.
Who is Rich Diviney:
Rich Diviney is a bestselling author, leadership and human performance expert, and retired Navy SEAL commander. During his career in the US Military, spanning more than twenty years, Rich has completed more than thirteen deployments overseas.
Chapters
0:00 - What makes a Navy SEAL not normal?
1:13 - Introduction to Rich Diviney
2:27 - The difference between SEALs, Delta, and CIA
3:35 - The "best at what" question
5:10 - Are SEALs knuckle-draggers?
7:47 - The dark side of deployment
10:45 - The sacrifice of military families
13:51 - Marriage in the special operations community
15:19 - Why empathy can be a challenge for a "team guy"
17:40 - The evolution of empathy
19:34 - Rich's mission: From SEALs to humans
20:58 - Stepping outside your comfort zone
24:08 - The Attributes Test & Compatibility
26:29 - The truth about BUD/S and athleticism
29:21 - Why athleticism is not a predictor of success
30:43 - The dopamine reward of hard things
33:57 - The challenge of mentally hard things
36:34 - Mastering the "little tragedies"
37:25 - The psychology of fear (uncertainty + anxiety)
41:56 - The Horizon Shifting technique
47:25 - The problem of free-floating anxiety
48:51 - How to reframe anxiety
51:08 - How to combine a physiological sigh with horizon shifting
53:41 - The "nail the exit" story
56:12 - Identity and its role in uncertainty
1:00:54 - Leading alpha types
1:01:52 - The power of hard things
1:03:50 - The subjectivity of failure
1:04:15 - A particular set of attributes
1:04:47 - Living a civilian life
1:07:37 - The edge
1:08:44 - The next horizon
1:09:50 - My dad's story
1:10:52 - What are the top two attributes of success?
1:14:13 - The courage switch
1:15:23 - The neurology of anxiety
1:16:46 - What advice would you give to someone who wants to be tougher?
1:18:13 - Closing remarks
1:21:18 - A funny story
1:24:00 - The Five Remembrances
1:25:01 - A moment of meditation
1:31:16 - Closing remarks
This episode is brought to you by:
LMNT - Free sample pack with any purchase at https://drinklmnt.com/DRLYON
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OneSkin - Get 15% off with the code DRLYON – https://www.oneskin.co
Our Place - Use Code DRLYON for 10% off sitewide at https://fromourplace.com/DRLYON
Find Rich Diviney at:
Instagram: https://www.instagram.com/rich_divineyX: https://x.com/richdivineyWebsite: https://theattributes.com/Buy His Book Masters of Uncertainty:https://theattributes.com/buy/book-masters-of-uncertaintyFind Dr. Gabrielle Lyon at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pagePre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 16 Sep 2025 - 1h 18min - 171 - The Truth About Hormones: Why Every Woman Should Consider Menopause Therapy
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In this episode, I sit down with nutritional physiologist and friend Nick Barringer, PhD, to tackle a crucial, yet often misunderstood, topic: women's hormonal health. We expose the devastating impact of the Women's Health Initiative study and why millions of women are left untreated for menopause symptoms, leading to an increased risk of issues like osteoporosis and Alzheimer's.
This is a no-nonsense guide for every woman, regardless of age, who wants to understand her hormones and advocate for her health. We cover everything from the importance of muscle and a low-inflammation lifestyle to the truth about Testosterone Replacement Therapy (TRT) for women.
This episode is sponsored by:
Puori - Use code DRLYON for 20% off - https://puori.com/DRLYON
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BON CHARGE - Use code DRLYON to get 15% off your entire order - https://boncharge.com/DRLYON
Needed - Use code DRLYON for 20% off your first order - https://thisisneeded.com
Chapter Markers
0:00 - Intro: Why women need to consider hormone therapy
1:24 - The shocking signs of low estrogen
2:31 - How the Women's Health Initiative did more harm than good
5:34 - The role of testing and delivery systems for estrogen
6:30 - Why women are undertreated for menopause
7:05 - The dangers of oral birth control
8:49 - Debunking "natural" hormone balancing
10:05 - The best delivery system for estrogen (patch vs. cream)
13:00 - The controversial topic of testosterone for women
14:48 - Debunking the myths of testosterone side effects
15:58 - The best way to dose testosterone for women
18:28 - Why hormone replacement alone won't change body composition
19:19 - Starting hormone therapy for perimenopause
20:53 - Vaginal estrogen for atrophy and UTIs
22:25 - A word from our sponsor, Paleo Valley
23:19 - Supplements for fat loss
27:38 - Modern anti-obesity drugs
31:18 - A word from our sponsor, AG1
32:48 - The best supplements for health and performance
40:07 - Testosterone, blood pressure, and side effects
41:51 - How women can take testosterone
43:10 - The importance of getting your blood work
43:40 - The risks of hormone replacement therapy
45:40 - Conclusion: A call to action for women's health
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Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 09 Sep 2025 - 45min - 170 - Ultimate Fat Loss Guide - Gabrielle Lyon - Mike Israetel - Layne Norton - Don Saladino
In this compilation, Dr. Gabrielle Lyon brings together the top minds in health and fitness to deliver the ultimate guide to fat loss. Featuring the best moments with Dr. Mike Israetel, Dr. Layne Norton, and Don Saladino, this video cuts through the confusion and gives you a no-nonsense, science-backed approach to transforming your body.
You’ll hear from the experts on everything from the flawed science of calories to the truth about muscle, metabolism, and modern weight loss drugs like Ozempic. This is not about fads or quick fixes—it’s a masterclass in building a sustainable, healthy body.
Dr. Mike Israetel: The fundamental principles of diet, the reality of "under-eating," and how to manage diet fatigue.
Dr. Layne Norton: The truth about flexible dieting, why calories still count, and the role of protein in weight loss.
Don Saladino: How to optimize your training for fat loss, the importance of consistency, and building a stronger mindset.
This is the only fat loss guide you'll ever need.
Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com
Chapters
0:00 - The Protein Debate Begins
1:31 - Debunking the Flawed Science of Protein
15:00 - The Myth of "Wasted" Protein
22:42 - The Truth About the RDA & What "Deficiency" Really Means
50:41 - The Problem with Plant Proteins & Caloric Cost
1:05:22 - The 100-Gram Protein Tipping Point
1:09:10 - Carbs vs. Protein: A Metabolic Showdown
1:13:15 - How to Diagnose a Protein Deficiency
1:18:13 - Final Thoughts: The Path Forward
This episode is sponsored by:
PaleoValley - Get 15% off automatically at https://paleovalley.com/DRLYON
AG1 - FREE gift with your first order at https://DrinkAG1.com/DRLYON
Timeline - Get 20% off your order at https://timeline.com/LYON
LMNT - Free sample pack with any purchase at https://drinklmnt.com/DRLYON
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Mon, 01 Sep 2025 - 1h 49min - 169 - Cancel Your Fear of Dying: How to Live Fully by Facing Death | Elena Brower
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We have all heard the sayings and clichés, but what is the truth behind being afraid of dying? In this episode, Dr. Gabrielle Lyon sits down with Elena Brower, a best-selling author, meditation teacher, and hospice volunteer, to discuss the profound topics of impermanence, living intentionally, and preparing for the end of life.
Drawing from her own experience with the loss of her mother, Elena shares her journey into hospice work and Buddhist chaplaincy, revealing how embracing the reality of death has become her most sacred practice. This conversation is not about morbidity but about using the awareness of death to live a more vibrant, present, and meaningful life.
Discover Elena Brower’s powerful new book, Hold Nothing, available now at https://elenabrower.com/holdnothing
Chapters:
0:00 - Intro
1:24 - The Five Remembrances
3:16 - Living with Impermanence
5:11 - The Two Kinds of Physicians
6:14 - Elena's Journey as a Hospice Volunteer
9:22 - Why Not Just Wait to be Afraid?
10:05 - The Power of Day-by-Day Awareness
13:34 - The Practice of Letting Go of Your Personality
15:40 - Making the Room Sacred
17:06 - Why Our Culture Turns Away from Death
23:02 - Do We Need Rituals?
26:39 - Talking to Children about Death
28:27 - Trauma, Grief, and Meeting Death Differently
30:20 - Zen Meditation vs. Other Modalities
38:54 - The Power of Friendship
45:45 - The Lightning Speed of Letting Go
46:33 - Cultivated Things
47:07 - Redefining Success
48:10 - Emptying Self-Doubt
49:30 - The Purpose of Self-Doubt
53:16 - Navigating Too Much Information
54:23 - Sitting Still and Weight Training
56:49 - Intergenerational Healing
59:09 - The Grandmother's Passing
1:01:36 - How Does Someone Become So Capable?
1:07:39 - The Most Powerful Form of Action
1:10:38 - Boundary Setting as an Act of Love
1:17:45 - The Altar of the Heart
1:19:22 - What to Say to Someone Who is Afraid of Dying
1:21:18 - A Quick Story
1:23:58 - Five Remembrances
1:25:01 - Meditation
1:31:16 - Closing Remarks
This episode is brought to you by:
Puori - Use code DRLYON for 20% off - https://puori.com/DRLYON
Manukora - Get $25 off your Starter Kit at https://manukora.com/DRLYON
BON CHARGE - Use code DRLYON to get 15% off your entire order - https://boncharge.com/DRLYON
ARMRA - Use code DRLYON to get 15% off your first order - https://tryarmra.com/DRLYON
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 26 Aug 2025 - 1h 31min - 168 - The Protein Debate: Dr. Layman Reacts to Dr. Gardner's claims on The Huberman Lab
In a powerful episode of the Dr. Gabrielle Lyon show, I sit down with my mentor, Dr. Donald Layman, to directly address some of the most common protein myths. We react to a controversial clip from the Huberman Lab podcast with Dr. Christopher Gardner, offering a different perspective on the conversation about protein intake, metabolic science, and dietary guidelines.
Dr. Layman, a pioneer in protein research, breaks down the outdated science behind the Recommended Dietary Allowance (RDA), the flaws of nitrogen balance studies, and why a protein-conscious approach is crucial for your long-term health, not just for building muscle.
This conversation is a must-listen for anyone who wants to cut through the confusion and understand what the science really says about protein, from its role in metabolism to why a grain-based diet may be leaving you deficient.
Want ad-free episodes, exclusive takeaways, and direct access to community Q&As? Subscribe to Forever Strong Insider and join me for deeper conversations, behind-the-scenes access, and more, every single week. Sign up here: https://foreverstrong.supercast.com
Chapters
0:00 - Intro: The Protein Debate
0:32 - Reacting to the Huberman Lab clip
1:31 - The flawed science of nitrogen balance studies
4:15 - The RDA's misleading "average requirement"
7:47 - The gross extrapolation of "deficiency"
10:41 - The original protein study subjects
12:15 - Why the RDA is much higher than the "minimum"
13:17 - Debunking the average American's protein intake
15:00 - Is there a storage depot for excess protein?
17:34 - The myth of protein being "wasted"
19:30 - Why some say protein metabolism is misunderstood
22:42 - Defining the RDA and EER
25:06 - Why Dr. Gardner's argument is flawed
27:17 - Why the nitrogen balance technique is wrong
32:37 - How to rectify the protein conversation
34:04 - Why we need to compare protein to carbs
41:09 - Comparing metabolic consequences of overeating carbs vs. protein
48:00 - Why a protein-conscious approach is critical
50:41 - Debunking the "incomplete" plant protein myth
55:28 - Do plant proteins have enough leucine?
1:02:45 - The myth of complimentary proteins
1:05:22 - The minimum protein for metabolic benefits
1:07:38 - The upper limit of protein
1:09:10 - The problem with "amino acid oxidation"
1:10:46 - The problem with amino acid supplements
1:13:15 - How do you diagnose protein deficiency?
1:18:13 - Debunking the "Americans eat the most meat" myth
PaleoValley - Get 15% off automatically at https://paleovalley.com/DRLYON
Timeline - Get 20% off your order at https://timeline.com/LYON
LMNT - Free sample pack with any purchase at https://drinklmnt.com/DRLYON
Our Place - Use Code DRLYON for 10% off sitewide at
https://fromourplace.com/DRLYON
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 19 Aug 2025 - 1h 21min - 167 - Erections & Testosterone - Shocking Link to Muscle Mass & Men's Health | Dr Tobias S Kohler
In this groundbreaking episode, Dr. Gabrielle Lyon sits down with Dr. Tobias Kohler, a professor of urology at the Mayo Clinic, to discuss a topic most people are afraid to talk about: men's sexual health.
Dr. Kohler shares eye-opening insights, backed by over two decades of clinical experience and research, on the powerful link between foundational health habits and male sexual function. They reveal why erectile dysfunction is a critical "check engine light" for heart disease and how building muscle and exercising can improve not just your erections, but your overall longevity.
This conversation goes beyond simple fixes, providing actionable, science-based information that every man needs to hear.
Looking to go deeper with The Dr. Gabrielle Lyon Show? Become a Forever Strong Insider for ad-free listening, written takeaways, behind-the-scenes access, and exclusive Q&A with our guests. Subscribe here: https://foreverstrong.supercast.com
This episode is brought to you by:
Puori - Get 20% off sitewide with code DRLYON → https://puori.com/DRLYON Cozy Earth - Use code DRLYON for up to 40% off - https://cozyearth.comBONCHARGE - Use code DRLYON for 15% off your entire order - https://boncharge.com/DRLYONOneSkin - Get 15% off with the code DRLYON – https://www.oneskin.coChapters
0:00 - Link between muscle mass & erections
0:52 - Erectile function
1:13 - The truth about penis size & penile implants
2:32 - The foundational pillars of men's health
8:48 - Erectile dysfunction is an early sign of heart disease
16:14 - The role of anxiety, alcohol & cannabis on ED
24:29 - The "use-it-or-lose-it" organ
29:31 - The truth about PDE5 inhibitors (Viagra & Cialis)
46:46 - The "C"s of urinary frequency
54:43 - The connection between muscle, testosterone & sexual function
1:02:07 - Is there a point of no return for penile health?
Erections: A “Check Engine Light” for Your Health
One of the most striking points from the discussion was Dr. Kohler’s perspective on erectile dysfunction (ED). He described it not just as a sexual problem, but as one of the earliest "check engine lights" for heart disease. The blood vessels leading to the penis are much smaller than those in the heart. As we age, plaque can build up in these vessels. This process, known as atherosclerosis, affects the smaller vessels first.
This means if you're experiencing persistent issues with erections, it's a strong indicator that you may have vascular problems that could soon affect your heart. As Dr. Kohler put it, "If the penis is failing, you should assume you're going to have problems with your heart soon until proven otherwise." The good news is that anything good for your heart—like exercise and a healthy diet—is also good for your penis.
The "Use-It-or-Lose-It" Organ
The conversation also tackled the surprising phenomenon of penile shortening. When the penis goes into a "garage" for an extended period—meaning there is a consistent lack of erections—it can lose length. Dr. Kohler shared that a consistent lack of erections for just three months can lead to a loss of 1-2 centimeters in length due to the formation of scar tissue. This is why he calls the penis a "use-it-or-lose-it" organ. The key to maintaining penile health is to exercise the penis through erections, and tools like a vacuum erection device can be used for penile rehabilitation.
Muscle Mass, Testosterone, and Sexual Function
For many men, this is where the conversation gets personal. Dr. Kohler highlighted the direct correlation between muscle mass and erectile quality. Studies show that men with more muscle mass have better erections and higher testosterone levels. The reverse is also true: men with less muscle mass often have lower testosterone, lower libido, and worse erections.
In fact, a modest 10% decrease in body weight can be as effective as ED medication in improving erections. Regular exercise also plays a huge role. Dr. Kohler cited a study that found 150 minutes of exercise per week decreased the rate of ED by 20%, while 300 minutes decreased it by nearly 40%. The takeaway is clear: if you want to improve your sexual function and overall longevity, you have to move iron and get strong.
The Pillars of Health and the Point of No Return
Dr. Kohler emphasized that before considering surgical options like a penile implant, men should focus on the foundational pillars of health: diet, exercise, sleep, and stress mitigation. These core tenants are the first line of defense against ED and other chronic diseases.
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 12 Aug 2025 - 1h 11min - 166 - The Truth About Sleep: Myths, Tips, and Longevity Secrets with Dr. Rebecca Robbins
Are you struggling to get a good night's rest?
Do you think you can thrive on just a few hours of sleep? In this eye-opening episode, Dr. Gabrielle Lyon sits down with renowned sleep scientist Dr. Rebecca Robbins to debunk the biggest sleep myths and reveal the profound connection between sleep and your health, longevity, and daily performance. They dive into the science of sleep, from the homeostatic sleep drive to the crucial role of your circadian rhythm. You’ll learn why sleep isn't just a passive state for your brain and discover the shocking truth about "social jet lag" and how hitting the snooze button is sabotaging your day.
In this episode, we cover:
Why sleep is your ultimate longevity accelerator and its impact on cognitive health and Alzheimer's.The dangers of sleep deprivation and how it affects your blood pressure, emotional regulation, and appetite.Actionable, evidence-based tips for improving your sleep, including the best time for naps and the surprising truth about sleep medication.The fascinating inner workings of your brain during different sleep stages, including deep sleep and REM sleep.The connection between your environment, exercise, and sleep quality.The future of sleep science and the exciting role of technology in tracking and improving your rest.The top 3 sleep myths you need to stop believing right now!
This conversation will change the way you think about sleep, empowering you to prioritize rest and unlock your full potential.
This episode is brought to you by:
LMNT - Free sample pack with any purchase at https://drinklmnt.com/DRLYON Timeline - Get 20% off your order at https://timeline.com/LYONMUD\WTR - Use code DRLYON to get up to 43% off your starter kit at https://mudwtr.com/DRLYONNeeded - Use code DRLYON for 20% off your first order at https://thisisneeded.comChapter Markers:
0:00 - Introduction & The Ultimate Accelerator of Good Health
0:10 - Sleep is a Product of Two Processes
0:30 - The Sleep Medication vs. Behavioral Change Debate
1:18 - The Importance of Sleep
2:21 - The Best Productivity Hack
3:16 - The Evolution of Sleep Science
5:52 - How Much Sleep Do We Really Need?
8:54 - The Two Processes That Drive Sleep
12:38 - Circadian Rhythm & Social Jet Lag
15:01 - Can You Repay Sleep Debt?
18:54 - What Happens to Your Brain When You Sleep?
20:10 - The Gold Standard of Sleep Measurement
22:35 - REM Sleep: The "Software Update" for Your Brain
26:42 - How to Find Your Child's "Sweet Spot"
30:32 - Navigating Jet Lag & Travel
33:10 - A Deep Dive into Melatonin
38:03 - The Impact of Exercise on Sleep
43:31 - The Power of Naps
47:01 - Tips & Tricks to Improve Your Sleep
50:18 - How to Create a Bulletproof Routine
58:50 - The Impact of Regular Sleep on the Brain
1:03:00 - Sleep Medication: The Pros and Cons
1:04:30 - The Future of Sleep Science
1:08:58 - The Top 3 Sleep Myths Debunked
1:12:35 - The Final Takeaway
Disclaimer:The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 05 Aug 2025 - 1h 13min - 165 - MCAS, POTS & Histamine Intolerance: Hidden Drivers of Chronic Symptoms | Michelle Shapiro, RD
Mysterious symptoms. Confusing diagnoses. Years of being dismissed.
In this episode, Michelle Shapiro joins me to unpack the often misunderstood and overlooked world of mast cell activation syndrome (MCAS), histamine intolerance, postural orthostatic tachycardia syndrome (POTS), and hypermobility conditions.
Drawing from her own health journey and experience with thousands of clients, Michelle unpacks why conventional medicine often overlooks these complex, overlapping conditions—and how a root-cause, systems-based approach can lead to real healing. From nervous system regulation to low-histamine nutrition, this episode is a must-listen for anyone struggling with unexplained chronic symptoms.
You’ll learn:
What MCAS is and why so many people are misdiagnosedThe link between MCAS, POTS, and connective tissue disordersHow nervous system regulation impacts immune reactivityWhich foods trigger histamine flares and how to build a low histamine dietThe surprising connection between hormones and histamine Why building muscle is critical for recovery from MCAS, POTS, and hypermobilityWhether you’re a clinician or someone living with these symptoms, this conversation offers insight, hope, and a roadmap forward.
Who is Michelle Shapiro?
Michelle Shapiro, RD is a functional/ integrative Registered Dietitian who has helped over 3,000 clients transform their health over the past 11 years. As the founder of an NYC-based virtual private practice, Michelle leads a team of six expert nutritionists who specialize in complex cases including histamine issues, gut dysfunction, chronic anxiety, and weight concerns. She is the creator of the viral Histamine Essentials Webinar, which is available now on replay, and the host of the top-rated podcast Quiet the Diet, where she breaks down the science behind chronic illness in a way that actually makes sense and makes you feel seen. Michelle is the go-to expert for people who have tried everything and are ready for a real plan.
This episode is brought to you by:
OneSkin - Get 15% off with the code DRLYON – https://www.oneskin.coNed - Get 15% off with code DRLYON – https://helloned.com/DRLYONBeef.org – Your go-to resource – https://BeefItsWhatsForDinner.comLMNT - Get your free LMNT Sample Pack with any purchase – https://DrinkLMNT.com/DRLYONFind Michelle Shapiro at:
Instagram - https://www.instagram.com/michelleshapirord Histamine Webinar Replay - https://michelleshapirord.com/histamine-webinar Apply to work with Michelle’s team: https://airtable.com/appzFCkAqbbL4J2Qu/pagw0ynsqYbBzMjes/formFind Me At:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Timestamps:
00:00 – Introduction: Dismissed symptoms and hidden syndromes
01:43 – What is mast cell activation syndrome (MCAS)?
03:33 – Why histamine is the “loudest” chemical messenger
06:39 – MCAS symptoms: from flushing to anxiety
08:22 – Root causes: mold, toxins, and the “bucket” theory
11:15 – Diagnosing MCAS: blood, urine, and biopsy challenges
15:11 – Food patterns: how "healthy" foods trigger MCAS
16:53 – MCAS vs histamine intolerance: what’s the difference?
25:06 – High-histamine foods: what to avoid (and why)
27:37 – Nervous system & immune system: the feedback loop
29:45 – Pepcid and unexpected MCAS symptom relief
33:23 – Protocols: antihistamines, electrolytes, and nervous system support
35:27 – What to eat on a low-histamine diet
40:02 – Vasodilation, migraines, and POTS explained
42:41 – How POTS mimics cardiac symptoms
45:15 – MCAS and POTS: which to treat first?
48:25 – How to safely exercise with POTS and MCAS
53:20 – The role of hypermobility and Ehlers-Danlos Syndrome
59:23 – Estrogen, progesterone, and histamine sensitivity
1:03:39 – Why building muscle is essential for stability and recovery
1:07:00 – Infrared, cold therapy, and root-cause detox (after stabilization)
1:12:32 – Supplements: quercetin, resveratrol, PEA, and more
1:13:37 – Hope for recovery—and why belief matters
1:20:15 – Final reflections and message of resilience
Tue, 29 Jul 2025 - 1h 22min - 164 - The Truth About Women’s Heart Health | Dr. Martha Gulati
Heart disease is the leading cause of death for women—yet it's still treated like a man’s disease. In this powerful conversation, Dr. Martha Gulati, a cardiologist and pioneer in women’s cardiovascular health, exposes the systemic gaps that leave women underdiagnosed, undertreated, and often unheard. Together, we unpack the critical differences in how heart disease presents in women, why standard diagnostic tools fall short, and what every woman needs to know about risk factors like pregnancy complications, hormone therapy, statin use, and even environmental exposures. Dr. Gulati also reveals the truth behind hormone therapy myths, explains how soft plaque really forms, and why fitness should be considered frontline prevention.
You’ll learn:
Why women’s heart symptoms are often mistaken for anxietyWhat tests to ask for to asses your risk of heart disease How statins, hormone therapy, and fitness interact with riskWhat the new “Prevent" risk score includes—and why it mattersWhy women get more benefits from exercise than menHow pollution, stress, and pregnancy complications shape long-term riskWhether you’re in your 20s or postmenopausal, this episode will empower you to take charge of your heart health, ask better questions, and get the care you deserve.
Who is Dr. Martha Gulati?
Dr. Martha Gulati is a professor of cardiology at the Smidt Heart Institute at Cedars-Sinai, where she serves as Director of Prevention and Associate Director of the Barbra Streisand Women’s Heart Center. She is the immediate past president of the American Society for Preventive Cardiology and previously served as the inaugural Chief of Cardiology at the University of Arizona. A leading voice in women’s heart health, Dr. Gulati chaired the first national chest pain guidelines and is the author of the best-selling book Saving Women’s Hearts.
This episode is brought to you by:
Manukora - Get $25 off the starter kit – https://manukora.com/DRLYON ARMRA – Code DRLYON for 15% off your first order – https://tryarmra.com/DRLYON Masa Chips - Code LYON for 25% off your first order – https://masachips.com/LYON Our Place – Code DRLYON for 10% off sitewide – https://fromourplace.com/DRLYONFind Dr. Martha Gulati At:
Website - https://drmarthagulati.com/ LinkedIn - https://www.linkedin.com/in/martha-gulati-9b410496/Instagram - https://www.instagram.com/drmarthagulati/X/Twitter - https://x.com/drmarthagulatiCedars-Sinai - https://www.cedars-sinai.org/provider/martha-gulati-2036029.htmlHer book Saving Women's Hearts: https://www.amazon.ca/Saving-Womens-Hearts-Conventional-Strategies/dp/0470678453Find Me At:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Timestamps:
00:00 – Intro and framing the crisis of heart disease in women
01:27 – Why women’s heart attack symptoms are often missed
04:28 – Why breast cancer awareness eclipsed heart disease awareness
07:01 – The legacy of excluding women from clinical trials
10:35 – The Women's Health Initiative and its impact on heart disease mortality
20:26 – The 3 key blood markers to assess heart disease risk in women
26:29 – Hormone replacement therapy: What went wrong
30:05 – Mythbusting: HRT does not replace statins
41:02 – Soft plaque vs. calcified plaque: what really matters
51:59 – Statins and brain health: separating fact from fiction
56:01 – INOCA: When women have symptoms without artery blockages
1:11:47 – Why “220 minus age” is inaccurate for women’s heart rate training
1:33:11 – Men’s vs. women’s hearts: anatomical and physiological differences
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 22 Jul 2025 - 1h 38min - 163 - Why Protein Isn’t Always Enough: Anabolic Resistance, Obesity, and Protein Efficiency | Dr. Nick Burd
Muscle health isn’t just about how much protein you eat—it’s about how your body uses it. And for people with obesity or advancing age, that process can become less effective, even with optimal nutrition.
In this episode, I am joined by Dr. Nick Burd, one of the world’s leading researchers in muscle metabolism, to unpack the concept of anabolic resistance—when muscle doesn’t respond normally to protein and/or exercise. Together, we explore how aging, obesity and even the way foods are combined on your plate can impact muscle remodeling, recovery, and growth. Dr. Burd also shares why plant-based proteins often fall short, why protein efficiency matters more than quantity, and how endurance and resistance training affect nutrient use differently.
You’ll learn:
What anabolic resistance is—and why it matters How to improve protein efficiency and muscle quality over timeWhy food matrix, and timing can change your resultsKey differences in nutrition strategies for endurance vs. strength athletesWhether you're focused on longevity, performance, or helping someone break through a plateau, this episode delivers the research-backed information you’ve been looking for.
Who is Dr. Nick Burd?
Dr. Nick A. Burd is a muscle-metabolism scientist and professor at the University of Illinois at Urbana-Champaign, where he leads the Nutrition & Exercise Performance Research Group. Originally from the Midwest, he trained under renowned experts around the world before focusing his research on how protein and exercise influence muscle health across the lifespan. His work uses advanced tracer methods and muscle biopsies to explore optimal protein intake, plant vs. animal protein quality, and strategies to combat anabolic resistance.
This episode is brought to you by:
LMNT - Get your free LMNT Sample Pack → https://drinklmnt.com/DRLYONCozy Earth - Use code DRLYON for up to 40% off - https://cozyearth.comTimeline - Get 20% off your order of Mitopure - https://timeline.com/LYONOneSkin - Get 15% off with code DRLYON → https://oneskin.coFind Dr. Nick Burd At:
University of Illinois at Urbana-Champaign: https://ahs.illinois.edu/burd X (Twitter): https://x.com/Nicholas_BurdGoogle Scholar: https://scholar.google.com/citations?user=BMvk_GMAAAAJ&hl=en LinkedIn: https://www.linkedin.com/in/nicholas-burd-5972b783/Find Me At:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Timestamps:
02:15 – Burd defines anabolic resistance and why it matters
03:30 – 36g of protein didn’t overcome anabolic resistance in obesity
05:00 – Obesity impacts myofibrillar, not mitochondrial synthesis
09:00 – Mechanisms of anabolic resistance in obese muscle vs. aging
12:50 – Muscle mass is intact, but quality is compromised in obesity
19:30 – Muscle protein synthesis is for remodeling, not always growth
27:30 – Leucine threshold depends on lean mass and age
30:20 – Obese muscle doesn't need more protein, needs better function
43:35 – Resistance training can improve protein efficiency
49:55 – Weightlifters often overeat protein without harm
54:00 – Protease enzymes may help older adults digest protein
1:02:56 – Vegan vs animal diets on muscle protein synthesis
1:44:30 –Ground meat matrix impaired anabolic response post-training
1:48:54 – Food matrix effects are food-specific—no one-size-fits-all answer
Disclaimer:The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 15 Jul 2025 - 1h 05min - 162 - How to Prevent Heart Disease with Mitochondria, Muscle, and the Endothelial Glycocalyx | Dr. Michael Twyman
Did you know every 40 seconds someone in the U.S. has a heart attack—and 1 in 5 never even see it coming? This week, I am joined by preventive cardiologist Dr. Michael Twyman as we discuss cutting-edge diagnostics, the endothelial glycocalyx, nitric oxide biology, and why muscle mass is your heart’s best friend. Learn the practical steps and questions to ask to protect your heart before symptoms appear.
Together, we explore:
Why silent heart attacks are so prevalentThe role of nitric oxide and the endothelial glycocalyx in vascular healthThe critical link between muscle mass, VO₂ max, and heart resilienceHow advanced imaging and testing are changing preventionDebunking common myths around cardiovascular riskSupplements and diagnostics Dr. Twyman uses to optimize cardiovascular healthThis episode is a masterclass in heart disease prevention—don’t miss it.
Who is Dr. Michael Twyman
Dr. Twyman is a board-certified cardiologist specializing in early detection and prevention of cardiovascular disease. Founder of Apollo Cardiology in St. Louis, he’s recognized for integrating advanced arterial imaging, mitochondrial health strategies, and personalized medicine to optimize long-term heart health. Dr. Twyman’s mission is to educate his patients on how to live better and longer by optimizing their mitochondrial function to become heart attack proof.
This episode is brought to you by:
Puori – Get 20% off sitewide with code DRLYON → https://puori.com/DRLYON Ned – Get 15% off with code DRLYON → https://helloned.com/DRLYON LMNT – Get your free LMNT Sample Pack → https://drinklmnt.com/DRLYONNeeded – Get 20% off your first order with code DRLYON https://thisisneeded.comFind Michael Twyman at:
Website - https://drtwyman.com/ Apollo Cardiology - https://drtwyman.com/apollocardiology/LinkedIn - https://www.linkedin.com/in/drtwyman/Instagram - https://www.instagram.com/drtwyman/X (Twitter) - https://x.com/michaeltwymanmdFind Me At:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Links to At-Home Tools/Testing Mentioned in the Episode:
Prebiotic Nitrate and Nitric Oxide salivary test strips (https://myfitstrip.com/) Blood pressure monitors: Omron Evolve (https://omronhealthcare.com/)and Cardiex Conneqt Pulse (https://cardiex.com/products/conneqt-pulse/)EKG monitor: Kardia (https://kardia.com/)Heart Rate Monitor with VO2Max and 1 lead EKG: Frontier (https://fourthfrontier.com/products/frontier-x) iHeart Internal Age App (https://goiheart.com/pages/iheart-internal-age)Oura Ring (https://ouraring.com/)Timestamps:
00:00 – Intro: The silent crisis of cardiovascular disease
03:00 – What is heart disease really, and who is at risk?
09:30 – How to screen for early cardiovascular disease
13:45 – What is a calcium score and why it matters
17:00 – The endothelial glycocalyx: Your artery’s armor
21:10 – Nitric oxide: The overlooked key to vascular health
26:00 – Red light therapy, UVA light, and nitric oxide production
32:45 – Biomarkers that matter more than LDL
40:10 – The truth about stress tests and cardiac imaging
45:00 – Erectile dysfunction as an early heart warning sign
51:00 – Testosterone, estrogen, and cardiovascular risk
56:20 – GLP-1s and new therapies for heart health
1:00:00 – Can diet and exercise reverse heart disease?
1:05:00 – Supplements Dr. Twyman recommends
1:10:00 – At-home tools for tracking heart health
1:15:00 – Muscle and VO₂ Max as heart disease predictors
1:20:00 – Final thoughts: Don’t guess—test.
Disclaimer:The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 08 Jul 2025 - 1h 43min - 161 - Stronger: The Untold Story of Muscle, Strength, and Human Potential | Michael Joseph Gross
In this episode, I’m joined by journalist and author Michael Joseph Gross, whose book, Stronger: The Untold Story of Muscle in Our Lives, reveals the powerful and often overlooked role of muscle in human health and society—tracing its importance from ancient civilizations to modern science. We explore how our understanding of muscle has evolved through history, from symbols of strength and vitality in antiquity to current misconceptions in modern society. Michael shares insights from his extensive research, highlighting the incredible resilience of muscle tissue, debunking common myths about strength and aging, and providing compelling evidence for why everyone—no matter their age or background—should prioritize building and preserving muscle.
We cover:
How muscle was viewed and valued from ancient cultures through modern timesWhy muscle mass is one of the strongest predictors of overall health and longevityHow muscle acts as an endocrine organ influencing metabolism, immunity, and cognitionThe common misconceptions about strength training, especially in women and older adultsHow the science of muscle can change your approach to fitness and longevityThe societal impact of muscle loss—and how we can turn it aroundThis conversation will leave you with a renewed appreciation for muscle—past, present, and future—and actionable insights to help you stay forever strong.
Who is Michael Joseph Gross?
Michael Joseph Gross is an accomplished journalist and author, widely recognized for his deeply researched, insightful explorations of human health and societal trends. His latest book, Stronger: The Untold Story of Muscle in Our Lives, delves into the transformative power of muscle from a biological, societal, and cultural perspective, offering groundbreaking insights into how muscle impacts our health, aging process, and overall quality of life.
This episode is brought to you by:
MASA Chips – Get 25% off your first order → https://masachips.com/LYONOneSkin – Get 15% off with code DRLYON → https://oneskin.coMUD\WTR – Get up to 43% off with code DRLYON → https://mudwtr.com/DRLYONLMNT – Get your free LMNT Sample Pack → https://drinklmnt.com/DRLYONFind Michael Joseph Gross at:
Get the book: https://www.michaeljosephgross.com/LinkedIn: https://www.linkedin.com/in/michael-joseph-gross-2937a5/Instagram: https://www.instagram.com/michaeljosephgrossFind Me At:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Timestamps:
00:00 – Introduction: Why muscle is the foundation of lifelong health
03:45 – Michael Gross’s journey into researching muscle health
08:20 – How muscle mass impacts metabolism, immune health, and cognition
14:50 – Debunking the myths around muscle loss and aging
21:05 – Muscle as an endocrine organ: How muscle influences systemic health
28:30 – Why strength training is essential, especially as we age
35:15 – The societal and economic impacts of widespread muscle loss
42:00 – Practical ways to build and maintain muscle at any age
50:00 – Michael’s key takeaways from his research on muscle and longevity
58:15 – Final thoughts: Prioritizing muscle for a stronger, healthier future
Disclaimer:The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 01 Jul 2025 - 1h 22min - 160 - Food & Metabolomics: How Your Diet—Starting in Childhood—Shapes Your Brain | Dr. Alexis Wood
In this episode, Dr. Alexis Wood, a leading researcher at Baylor College of Medicine, joins me to unpack insights into childhood nutrition, genetics, and cognitive health. Dr. Wood's work bridges genetics, dietary practices, and brain development, highlighting how early-life nutrition can shape lifelong outcomes. We explore cutting-edge research, practical strategies for parents, and the surprising factors influencing children's cognitive and metabolic health.
We cover:
Why childhood nutrition and genetics have been historically overlooked—and what it means for your family.ADHD and diet: Separating fact from fiction.Debunking popular diet myths: What the research actually says about red meat and processed foods.Cognitive self-regulation: The hidden link between diet, obesity, and ADHD. Precision nutrition & metabolomics: The future is more than one-size-fits-all advice.Whether you're a parent, educator, or health professional, this conversation offers guidance on navigating the complex relationship between nutrition, genetics, and childhood development.
Who is Dr. Alexis Wood?
Dr. Alexis Wood, Ph.D., F.A.H.A., is an Associate Professor of Pediatrics–Nutrition at Baylor College of Medicine’s USDA/ARS Children’s Nutrition Research Center. Her research integrates genetics, child development, and nutrition, focusing on how genetic factors influence responses to diet and behavior.
This episode is brought to you by:
PaleoValley - Get 15% off at https://paleovalley.com/drlyonARMRA – Use code DRLYON to get 15% off your first order at https://tryarmra.com/DRLYONOur Place - Use code DRLYON for 10% off sitewide – https://fromourplace.com/DRLYON Timeline - Get 20% off your order of Mitopure - https://timeline.com/LYONFind Dr. Alexis Wood at:
Linked In - https://www.linkedin.com/in/lekkiwood/Baylor College of Medicine - https://www.bcm.edu/people-search/alexis-wood-33281USDA/ARS Children's Nutrition Research Center - https://www.bcm.edu/research/research-centers/usda-ars-childrens-nutrition-research-centerAlexis Wood Lab - https://www.bcm.edu/research/faculty-labs/alexis-lekki-wood-labFind Me At:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Timestamps:
00:00 - Introduction and overview
01:25 - Current landscape of childhood nutrition and genetics
04:00 - Challenges and opportunities in studying child nutrition
07:39 - ADHD, genetics, and dietary myths
12:23 - Clinical evidence on diet and ADHD
14:18 - The Mediterranean diet and childhood nutrition
17:48 - Debunking myths around red meat consumption
22:55 - Metabolomics: Precision nutrition’s new frontier
28:39 - The genetics of cognitive self-regulation and obesity
34:50 - Nutrition’s role in cognitive health across the lifespan
39:57 - What are metabolites and why do they matter?
44:29 - Interpersonal variability in nutrition responses
48:52 - The milestone "MILES" metabolomics study
52:21 - Processed foods: Balancing health and reality
58:19 - Early life behaviors and aging
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 24 Jun 2025 - 1h 10min - 159 - Are Red Meat Warnings Based on Flawed Science? Dr. David Klurfeld on Nutrition Myths and Industry Bias
In this episode, I sit down with Dr. David Klurfeld—longtime USDA scientist and one of the few insiders to publicly challenge the WHO's classification of red meat as a carcinogen. We go deep into the flawed evidence behind the infamous 2015 IARC report, why nutritional epidemiology often fails to prove causality, and how a small group of researchers helped shape global policy with low-quality science. If you've ever felt confused about meat, saturated fat, or dietary guidelines, this conversation will help you think critically about what “counts” as evidence—and who gets to decide.
We cover:
Dr. Klurfeld’s personal journey and lessons from a career in public healthWhy the 2015 IARC red meat classification was based on weak and inconsistent evidenceHow observational studies and “allegiance bias” mislead nutrition scienceThe politics of dietary guidelines and the role of the USDA and WHOWhat the media got wrong—and why red meat remains a nutrient-dense foodWhether you're a clinician, dietitian, or simply trying to make better nutrition decisions, this episode is a powerful reminder that bias, groupthink and weak data can distort science and mislead the public. We need to be discerning about the nutrition and health advice we follow.
Who is Dr. David Klurfeld?
Dr. David Klurfeld is a nutritional scientist and former National Program Leader for Human Nutrition at the USDA’s Agricultural Research Service. He also served as Professor and Chair of Nutrition and Food Science at Wayne State University and Associate Editor of The American Journal of Clinical Nutrition. He has authored more than 200 scientific publications and was one of 22 experts invited to the 2015 IARC working group on red meat and cancer. He is a longtime advocate for scientific integrity in public health policy.
This episode is brought to you by:
LMNT- Free Sample Pack with any purchase, visit https://DrinkLMNT.com/DRLYONTimeline - Get 20% off your order of Mitopure - https://timeline.com/LYONMUD\WTR - Use code DRLYON to get up to 43% off your starter kit - https://mudwtr.com/DRLYONNeeded - Use code DRLYON for 20% off your first order - https://thisisneeded.comFind Dr. David Klurfeld at:
Indiana University Bloomington - https://publichealth.indiana.edu/about/directory/David-Klurfeld-dmklurfe.htmlGoogle Scholar - https://scholar.google.ca/citations?user=Ym5Og20AAAAJ&hl=en LinkedIn - https://www.linkedin.com/in/david-klurfeld-812845209/Find me at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Timestamps:
00:00 – Dr. Gabrielle Lyon introduces Dr. David Klurfeld and the controversy around red meat and cancer.
03:18 – Dr. Klurfeld explains his unconventional path into nutrition science and his early influences.
06:07 – He describes how "allegiance bias" distorts nutrition research outcomes.
09:08 – Klurfeld calls the IARC red meat classification “the most frustrating professional experience of my life.”
12:15 – He explains why epidemiology and food questionnaires are unreliable for determining dietary risk.
15:30 – Red meat is misleadingly grouped with engine exhaust and radiation in cancer risk categories.
22:15 – Many IARC scientists had pre-existing biases and used the panel to reinforce prior publications.
26:08 – Klurfeld critiques the misuse of correlation in nutrition
32:06 – He debunks the commonly cited 17% increase in colorectal cancer risk from red meat.
38:50 – Klurfeld details his role overseeing USDA human nutrition research and Dietary Guidelines input.
48:44 – Activist groups filed FOIA requests to access years of Klurfeld’s emails during public-private research.
1:09:21 – He explains why nitrogen content alone is an inadequate way to assess protein quality.
Disclaimer:The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 17 Jun 2025 - 1h 49min - 158 - Why Men’s Fertility Is Declining: The Truth About Testosterone | Dr. Larry Lipshultz
Dr. Larry Lipshultz. is one of the world's leading experts in men's reproductive health. In this week's episode, we discuss testosterone therapy, male fertility, and the hidden environmental factors threatening men’s health. Dr. Lipshultz shares groundbreaking insights into why male fertility is declining, common myths surrounding testosterone and prostate cancer, and innovative strategies to safely enhance men's reproductive and overall health.
We cover:
The alarming 50% drop in male fertility since the 1980s—and what’s driving itTestosterone therapy myths: prostate cancer, fertility, and what’s actually truePractical treatments for restoring fertility while on testosterone therapyAnabolic agents: risks, benefits, and smart usePersonalized, patient-centered care to optimize male reproductive and overall healthIf you care about men's health, fertility, or hormone optimization, this conversation is a must-listen.
Who is Dr. Larry Lipshultz?
Dr. Lipshultz’s research focuses on male reproductive dysfunction, testosterone therapy, cardiovascular risk, and the genetics of infertility. He has pioneered innovations in testicular sperm extraction, vasectomy reversal, and testosterone optimization therapies. With over 460 peer-reviewed publications and as co-author of a foundational textbook on andrology, his contributions have significantly enhanced diagnostic approaches in male infertility. An early recipient of the American Urological Association Research Scholar award, he advocates for integrative andrologic health as a foundation for lifelong wellness.
This episode is brought to you by:
Puori - Get 20% off sitewide with Code DRLYON - https://Puori.com/DRLYONCozy Earth - Use code DRLYON for up to 40% off - https://cozyearth.comTimeline - Get 20% off your order of Mitopure - https://timeline.com/LYONManukora - Get $25 off the Starter Kit - https://manukora.com/DRLYONFind Dr. Lipshultz at:
Website - https://www.larrylipshultz.com/Baylor College of Medicine - https://www.bcm.edu/people-search/larry-lipshultz-25437 LinkedIn - https://www.linkedin.com/in/larry-lipshultz-md-93977344/Find Me At:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Timestamps:
00:00 – Introduction & the critical but overlooked importance of male fertility for men's health.
02:29 – Dr. Lipshultz describes pioneering the specialty of male infertility early in his medical career.
08:38 – Confirmation of a significant decline (50%) in global sperm quality since the 1980s.
15:00 – Discussion on how environmental toxins negatively affect male fertility.
25:46 – The importance of age & female fertility; highlighting risks after age 35.
29:50 – Practical advice on improving sperm quality through lifestyle changes, antioxidants, and avoiding excessive heat.
40:19 – Overview of testosterone therapy's potential negative effects on sperm production.
46:47 – Dr. Lipshultz reflects on training over 100 fellows as his most impactful career contribution.
55:38 – Insights on the cautious and safe clinical use of anabolic agents
1:02:15 – The necessity of preserving muscle mass in older adults through anabolic support.
1:27:36 – Benefits of microdosing testosterone to minimize side effects such as elevated hematocrit.
1:42:47 – Strategies for restoring male fertility after testosterone therapy.
Disclaimer:The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 10 Jun 2025 - 1h 47min - 157 - How to Train Your Mind: Ancient Wisdom, Modern Science, and the Mindset of Excellence | Brian Johnson
What if your biggest challenge isn’t motivation but missing structure? In this episode, I sit down with Brian Johnson to unpack the science and philosophy of lasting behavior change. We explore the power of ancient wisdom, stoicism, and the neuroscience of excellence, and why most wellness apps fail to deliver real transformation.
Brian shares his personal journey from startup success to creating a global movement around character, discipline, and identity-based habits. We talk about the science of anti-fragility, how muscle mirrors virtue, and why the gap between who you are and who you could be is the true source of suffering. Whether you're a high performer or someone who wants to stop breaking promises to yourself, this conversation will help you build the structure to show up as your best—no matter the circumstance.
What You’ll Learn:
Why most behavior change fails—and what the science says worksThe philosophy of Areté: how to close the gap between potential and actionHow ancient stoicism aligns with modern recovery, resilience, and muscleWhy building muscle is a metaphor (and mechanism) for building characterThe true definition of anti-fragility—and how to train itIf you're ready to bridge the gap between knowing and doing, this episode is the roadmap you've been looking for.
Who is Brian Johnson?
Brian Johnson has spent half of the last 25 years as a Founder/CEO and the other half as a Philosopher. As a Founder/CEO, he’s made crowdfunding history and built and sold two market-leading social platforms. As a Philosopher, he created Philosopher’s Notes, wrote the bestselling book Areté: Activate Your Heroic Potential, and developed a protocol integrating ancient wisdom, modern science, and practical tools that has been scientifically proven to help people change their lives. Brian is featured in the documentary Finding Joe on the modern Hero’s Journey and has trained some of the world’s most elite performers. He lives in the country outside of Austin with his wife and two kids and is all in on fulfilling Heroic’s mission to help create a more noble and virtuous world in which 51% of humanity is flourishing by 2051.
This episode is brought to you by:
LMNT- Free Sample Pack with any purchase, visit https://DrinkLMNT.com/DRLYONAG1 - FREE bottle of AG D3K2, an AG1 Welcome Kit + 5 travel packs with your first order – https://drinkAG1.com/DRLYONOneSkin - Use Code DRLYON for 15% off OneSkin – https:// www.oneskin.coTimeline -20% off your order of Mitopure visit https://timeline.com/LYONFind Brian Johnson at:
Learn more about Brian Johnson and Heroic and get some free content just for my listeners: heroic.us/drlyon Tiktok: https://www.tiktok.com/@heroicbrianInstagram: https://www.instagram.com/heroicbrian/Facebook: https://www.facebook.com/heroicbrian/Linkedin: https://www.linkedin.com/in/heroicbrian/YouTube: https://www.youtube.com/@HeroicBrianFind Me At:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Timestamps:
00:00 – Introduction: Philosophy meets behavioral science and the art of heroic living.
01:14 – Welcoming Brian Johnson and his journey into philosophy and personal growth.
03:27 – Brian’s early career and building online platforms pre-Facebook.
05:02 – Discussion about stoicism, virtues, and how Brian became interested in philosophy.
20:23 – The importance of teaching foundational principles like willpower and virtue to children.
22:44– Identifying behaviors to optimize energy, work, and love.
31:23 – How tranquility, calm, and greatness require intentional thinking and reflection.
41:46 – Balancing ambition, virtue, and influence; discussion on noble motivations and leadership.
53:09 – Using physiology to control psychology, mental resilience, and self-management.
56:21 –The importance of quickly recovering emotional balance and equanimity.
1:01:22 – How recognizing and learning from past mistakes contributes to personal growth.
1:03:11 – Raising heroic children and living against the norms of a "sick society."
1:12:31 – Brian’s mission to help humanity flourish and his personal commitment symbolized by a tattoo.
1:14:36 – Brian discusses his book, Arete, and how to cultivate personal excellence.
Disclaimer:The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 03 Jun 2025 - 1h 15min - 156 - Understanding Heart Rate Variability: Improving Your Health & Performance | Joel Jamieson
When it comes to performance, more isn’t always better. In this episode, I sit down with conditioning expert Joel Jamieson to explore the science of recovery, aerobic fitness, and how to use heart rate variability (HRV) to train smarter. They dive into why elite athletes recover so quickly, the long-term value of zone 2 training, and how HRV reflects your resilience—not just your readiness. Joel shares lessons from two decades of working with fighters, Olympians, and NFL players, along with powerful insights from his own cardiovascular health journey. Whether you’re a high performer or simply want to live longer and stronger, this episode is packed with practical takeaways.
In this episode, you’ll learn:
What HRV actually tells you—and what it doesn’tWhy aerobic fitness is one of the strongest drivers of recovery and longevityThe surprising downside of too much strength trainingHow to monitor training load and avoid overtrainingWhy lifestyle stress matters more than your workoutThis episode will change the way you think about training—and reveal why recovery deserves a central role in your performance strategy.
Who is Joel Jamieson?
Joel Jamieson is a leading coach and educator in recovery-based training and heart rate variability (HRV). With over 20 years of experience working with professional athletes, including NFL players and world champion fighters, he’s known for translating complex performance science into practical tools. He’s the creator of Morpheus, a system that helps tailor training to daily recovery status, and the founder of 8WeeksOut, a resource for conditioning and performance education.
This episode is brought to you by:
Puori - Code DRYLYON to get 20% off sitewide - https://Puori.com/DRLYONMUD\WTR - Code DRLYON to get up to 43% off your starter kit - https://mudwtr.com/DRLYONBON CHARGE - Code DRLYON to get 15% off your entire order - https://boncharge.com/DRLYONARMRA - Code DRLYON to get 15% off your first order - https://tryarmra.com/DRLYONFind Joel Jamieson at:
Instagram: @coachjoeljamieson8WeeksOut: https://8weeksout.com/Morpheus: https://trainwithmorpheus.com/Find Me At:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Timestamps:
0:00 – Intro: Why recovery matters more than you think
4:10 – Joel’s early coaching career and discovery of HRV
9:45 – Lessons from training world-class combat athletes
14:50 – What HRV really measures—and what it doesn’t
20:00 – Genetic advantages: Why elite athletes recover faster
24:05 – Aerobic fitness as the foundation for recovery and longevity
28:40 – How to improve HRV with zone 2 and low-intensity training
35:15 – Joel’s personal heart health wake-up call
43:10 – Why bloodwork isn’t enough: What CT angiograms can reveal
50:20 – Lifestyle stress vs. training stress: What matters more
57:00 – The limitations of wearables and how to use HRV properly
1:03:45 – Cold plunges, breathwork, and the two types of recovery
1:11:05 – The real-world data: Why most people train too hard
1:17:30 – Final thoughts on resilience, training smarter, and the future of recovery
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 27 May 2025 - 1h 59min - 155 - Why Do Most Diets Fail? The Science of Nutrient Deficiencies | Ty Beal PhD
In this episode, I’m joined by Dr. Ty Beal—global nutrition researcher and Senior Technical Specialist at the Global Alliance for Improved Nutrition (GAIN)—to uncover the hidden epidemic of micronutrient deficiencies worldwide. From food access and affordability to ultra-processed diets and nutrient bioavailability, we explore how modern food systems are failing billions and what needs to change to truly make the world healthier.
We cover:
Why 3 billion people can’t afford a healthy diet—and how that affects nutrient statusThe most common global and U.S. micronutrient deficiencies (and why they’re often overlooked)Why women and children are especially vulnerable during pregnancy, infancy, and adolescenceThe role of ultra-processed foods in displacing nutrient-rich optionsHow bioavailability, anti-nutrients, and the “food matrix” impact your real nutrient intakeWhy plant-based diets aren’t always safer—and the hidden risks of nutrient shortfallsThe science behind biofortification, food system reform, and why animal-source foods stil matterWhat the U.S. gets wrong about food guidelines, global trade, and nutritional equityWhether you care about maternal health, child development, or just making better nutrition decisions, this is a vital conversation about nutrient density, food justice, and global health.
Who is Dr. Ty Beal?
Dr. Ty Beal is a Senior Technical Specialist and global nutrition scientist at the Global Alliance for Improved Nutrition (GAIN) where he leads research on global food systems, nutrient inadequacy, and diet quality. His work bridges science and policy to help address the world’s most pressing nutrition challenges—especially among vulnerable populations. He’s published extensively on micronutrient gaps, ultra-processed foods, and global dietary patterns, and is one of the most cited voices on nutrition equity in developing nations.
This episode is brought to you by:
LMNT – Code DRLYON for a free LMNT Sample Pack! → https://drinklmnt.com/drlyonTimeline – Get 10% OFF Mitopure with code DRLYON → https://timelinenutrition.com/LYONNed – Get 15% off with code DRLYON → https://helloned.comOur Place – Get 10% off sitewide with code DRLYON → https://fromourplace.com/DRLYONFind Dr. Ty Beal at:
GAIN Health - https://www.gainhealth.org/ty-beal Google Scholar - https://scholar.google.com/citations?user=3y5uHRIAAAAJ&hl=en X (Twitter) - https://x.com/TyRBeal LinkedIn - https://www.linkedin.com/in/tybeal/Find Me at:
Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageGet my book – https://drgabriellelyon.com/forever-strong/Timestamps:
00:00 – Why global food systems are broken—and why it matters in the U.S. too
02:06 – 3 billion people can’t afford a healthy diet: what that really means
05:16 – The most common micronutrient deficiencies in women and children
09:10 – How early nutrient gaps impact growth, cognition, and lifelong health
13:28 – The hidden risks of plant-based diets for nutrient shortfalls
17:35 – Food matrix vs. supplements: why real food still matters most
20:47 – How ultra-processed foods displace nutrient-dense options
29:42 – Are Americans really eating too much meat? The data says otherwise
36:00 – What’s wrong with global dietary guidelines and who sets them
44:06 – How to produce nutrient-dense food without harming ecosystems
50:00 – Biofortification: breeding crops to fight nutrient deficiencies
52:15 – What balance of plant and animal foods actually supports health
Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Tue, 20 May 2025 - 1h 10min
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