Filtra per genere
Welcome to Biohacking Beauty, the definitive exploration of skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, this podcast moves beyond "single-molecule" trends to uncover the multi-mechanism protocols required to optimize the body’s largest organ. We bridge the gap between systemic longevity research and topical application. By hosting world-renowned experts in mitochondrial health, epigenetic signaling, and regenerative medicine, we translate complex research into actionable strategies for biological recalibration. From the 12 Hallmarks of Aging to the latest in bio-harmonizing lifestyle shifts, Biohacking Beauty provides the molecular tools and insights needed to align your skin’s appearance with your body’s peak biological potential.
- 277 - 278. Dr. Amy Spizuoco: Ozempic Hair Loss, Biotin Myths, and Hair Treatments That Actually Work
Most people treat hair, scalp, and skin as three separate problems, each with its own shelf of products. But all three are built from keratin and run on the same growth signals, so thinning hair can say as much about how you're aging as a new wrinkle.
We dive deeper into this in the Biohacking Beauty Podcast with Dr. Amy Spizuoco. We also chat about what's really behind Ozempic hair loss, which hair loss treatments hold up in the evidence, and the popular hair supplement she calls the biggest waste of money.
Dr. Amy Spizuoco, DO, FAOCD, FAAD, is a board-certified dermatologist and dermatopathologist and the founder of True Dermatology in New York City. She is a Clinical Instructor of Dermatology at the Icahn School of Medicine at Mount Sinai, past president of the American Osteopathic College of Dermatology, and serves on the editorial boards of Practical Dermatology and Dermatology Times. She is also co-founder and co-chair of the DermVIP Summit, a dermatology conference dedicated to hair loss and scalp conditions.
What’s Discussed:
(01:25) Why hair, scalp, and skin are more connected than three product shelves suggest.
(04:14) How collagen 17 links thinning hair and thinning skin.
(07:17) Why the future of collagen is protecting what you have, not just rebuilding it.
(10:09) What gray hair and cell senescence reveal about aging in the rest of the body.
(15:26) When to start scalp care, and the scalp symptoms that need attention right away.
(20:33) How the hair growth cycle shortens as you age.
(29:31) What's really behind Ozempic hair loss, and what to put in place before starting a GLP-1.
(37:17) PRP, red light caps, and exosomes: which hair loss treatments actually hold up.
(45:46) The truth behind retinoid "thinning" and finasteride side effects.
(49:54) The hairline changes that mean you should see a dermatologist now.
(53:16) The hair supplement Dr. Amy calls the biggest waste of money.
Listen to this episode of Biohacking Beauty before you spend another dollar on biotin, scalp serums, or rosemary oil.
Resources Mentioned:
Xtressé Nutrient Hair Growth Gummies:shop.advancedderm.com
Related Episodes:
Dr. Alan Bauman: Why Biohackers Are Losing Their Hair Faster Than Everyone Else
Q&A: Your Questions Answered on Exosome Skincare (Everything You Need to Know Before You Try)
Find more from Young Goose:
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at younggoose.com
Instagram: @young_goose_skincare
Find more from Dr. Amy Spizuoco & True Dematology:
Website: true-dermatology.com
Instagram: @drspizderm
Wed, 04 Nov 2026 - 54min - 276 - 277. Dr. Carrie Jones: Perimenopause Skin Changes, Hidden Histamine Triggers, and the Labs Worth Asking For
In your 40s, skin can suddenly turn red, itchy, flaky, or reactive, sometimes in random places, and most women assume it is just aging or blame their skincare. But the estrogen and progesterone shifts of perimenopause can change how mast cells release histamine at the skin barrier, which means the trigger may be happening inside the body, not inside the bottle.
We dive deeper into this in the Biohacking Beauty Podcast with Dr. Carrie Jones. We also chat about why a retinoid you have used for years can suddenly irritate your skin, why wine hits so differently in your 40s, and the overlooked lab that could explain hair loss and fatigue.
Dr. Carrie Jones, ND, FABNE, MPH, MSCP, is a naturopathic physician who completed a two-year residency in women's health and endocrinology, is board certified through the American Board of Naturopathic Endocrinology, and is a Menopause Society Certified Practitioner. She was the first medical director for Precision Analytical (the DUTCH Test) and the first head of medical education at Rupa Health. She has more than 20 years of experience in women's health and hormones and hosts the Hello Hormones podcast.
What’s Discussed:
(00:21) Why skin can suddenly turn red, itchy, and reactive in your 40s.
(02:20) Why a retinoid you have used for years can start irritating your skin in perimenopause.
(06:00) How mast cells and histamine create redness, welts, and itching that seem random.
(09:43) How bone broth and fermented foods can add to an already full histamine bucket.
(12:01) Why wine affects your liver, hormones, and skin differently in perimenopause.
(16:59) Alcohol-free ways to wind down at night, from holy basil tea to magnesium.
(20:50) What it means if an antihistamine before bed helps you wake up feeling better.
(23:28) Why progesterone is often the first hormone to drop and how that affects mast cells.
(27:46) The overlooked histamine trigger that can worsen PMS and skin, plus the biggest lever of all.
(35:01) Why ferritin belongs on your blood work, how low is too low, and when supplements are not enough.
(43:27) What to ask your doctor for, so you leave with more than another cortisone cream.
(48:27) Rapid fire: estrogen dominance, seed cycling, red wine, and the one thing every woman over 40 should stop doing.
Listen to this episode of Biohacking Beauty before you blame your next flare on aging or your skincare routine.
Resources Mentioned:
Mira Hormone Monitor:miracare.com
Find more from Young Goose:
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at younggoose.com
Instagram: @young_goose_skincare
Find more from Dr. Carrie Jones:
Website: drcarriejones.com
Instagram: @dr.carriejones
YouTube: Dr. Carrie Jones
Podcast: Hello Hormones with Dr. Carrie Jones
Wed, 28 Oct 2026 - 54min - 275 - 276. Skincare Routine by Age: The Science-Backed Protocol for Your 20s, 30s, 40s and 50s
Most skincare routines are built by accumulation: a serum that went viral, a cream a friend swore by, whatever promised firmer skin that month. But what drives skin aging at 25 is not what drives it at 45, so a routine that never changes its priorities can spend years working on the wrong problem.
And your birthday is only part of the picture. Some people's skin is running a decade ahead of their age, perimenopause can change what skin needs years before the 40s arrive, and the routine you will actually stick with is usually shorter than the one you think you need. So before you add another product, it is worth knowing what changes in your skin from one decade to the next and what each stage should prioritize.
In this Biohacking Beauty Class, we walk through a skincare protocol for every decade, from protection in your 20s to correction in your 30s and recovery in your 40s, 50s, and beyond. We get into the research tying sun exposure to 80% of visible facial aging, why NAD+ declines in aging skin, what makes many exosome formulas questionable, how to tell if your skin is aging ahead of your age, and the red light specs that actually matter.
What’s Discussed:
(02:17) Why your skin's age matters more than the number on your birthday.
(03:09) The "attention budget" and why a shorter routine often gets better results.
(04:44) The research linking sun exposure to 80% of visible facial aging.
(06:20) What happened when adults used sunscreen every day for four and a half years.
(12:06) Why NAD+ declines in aging skin and what changes after 30.
(15:03) How spermidine and autophagy help skin clear out what has expired.
(22:08) Why exosomes cannot survive alongside vitamin C, acids, and peptides in the same formula.
(24:04) The part of aging in your 40s that sunscreen cannot fully cover.
(26:10) Why perimenopause and menopause mean moving up a stage, whatever your age.
(31:22) A first look at the Youth Activating Ampoule and why some actives have to stay freeze-dried.
(42:05) What to use at home in the weeks around microneedling and laser treatments.
(45:25) What the research says about red light therapy and the specs worth paying for.
(51:53) How to find out if your skin is aging ahead of your age.
Listen to this episode of Biohacking Beauty before you add another product to your routine, so you know what your skin needs at the stage it is actually in.
Resources Mentioned:
Skincare by Age protocol: https://www.younggoose.com/pages/science
Decade-by-Decade Skincare Field Guide
Find a Young Goose Professional
Previous Episodes Mentioned:
Anastasia and Amitay with Dave Asprey on The Human Upgrade
Find more from Young Goose:
Website:Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Wed, 21 Oct 2026 - 50min - 274 - 275. Dave Asprey: The Uncomfortable Conversation About Aging Naturally vs. Biohacking
There is an interesting contradiction in the way we talk about aging. We celebrate using technology to improve sleep, metabolism, cognition, recovery, and longevity, but when the same mindset is applied to appearance, the conversation can suddenly become much more judgmental.
In this episode of Biohacking Beauty, we sit down with Dave Asprey to explore that tension. We get into why he chose a facelift after major weight loss, whether cosmetic procedures belong in the biohacking conversation, and why wanting to look younger is often treated differently from wanting the rest of your body to function younger.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, CEO of Upgrade Labs, host of The Human Upgrade, and co-founder of Unlimited Life. We also talk about how he prepares his body before procedures, what he thinks people misunderstand about peptides, and his takes on GLP face, collagen supplements, Botox, stem cells, and the other tools people are using to change how they age.
What’s Discussed:
[13:02] Why Dave ultimately chose a facelift after major weight loss.
[15:24] Where non-surgical skin treatments reached their limit for the amount of excess skin he wanted to address.
[18:58] Why copying someone else’s longevity or supplement stack can backfire.
[28:59] Where to start when your biological-age markers look good but you still do not like what you see in the mirror.
[30:07] Why sleep, recovery, HRV, and other foundational markers still matter when thinking about aging.
[37:52] The stigma around cosmetic procedures in biohacking and why Dave questions where that line is drawn.
[44:56] Why he believes fear around aging and medical procedures can affect the body’s stress response.
[54:25] GLP-1s, muscle loss, and the changes people notice in facial appearance after weight loss.
Listen to this episode of Biohacking Beauty for a conversation about where “aging naturally” ends, where biohacking begins, and why that line becomes much more complicated when appearance enters the picture.
Find more from Young Goose:
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off atyounggoose.com
Instagram: @young_goose_skincare
Find more from Dave Asprey:
Website:daveasprey.com
LinkedIn: Asprey
Instagram:@dave.asprey
Facebook: Daveaspreyofficial
YouTube: DaveAspreyBPR
TikTok: @daveaspreyofficial
Book: “Heavily Meditated”: https://daveasprey.com/heavily-meditated/
Wed, 14 Oct 2026 - 48min - 273 - 274. The Peptide Skincare Boom: Separating Skin Science From Marketing
Peptides are everywhere in skincare right now. They are in serums, moisturizers, lip products, cleansers, body washes, and even shampoos, all promising some version of smoother skin, more collagen, or fewer visible signs of aging.
But seeing “peptides” on a label tells you very little about whether the product can actually deliver those results. Which peptide is being used? Is there research behind that specific ingredient? Is there enough of it in the formula? Can it get through the skin barrier? And what happens when it is combined with everything else inside the bottle? So before you buy another peptide serum because the ingredient sounds impressive, it is worth knowing what actually makes a peptide useful for your skin and how formulation, delivery, concentration, and the rest of your routine can affect whether it works at all.
In this Biohacking Beauty Class, we are separating the science from the marketing around topical peptides. We get into which ones have more evidence behind them, what “Botox in a bottle” gets wrong, why some peptide products make more sense than others, and what to look for if your goal is supporting collagen, softening fine lines, and keeping your skin functioning well as it ages.
What’s Discussed:
(01:47) Do peptides actually belong in everything from serums to body wash?
(05:17) The biggest red flag when a skincare product uses peptides as the main selling point.
(08:26) What should actually back up an anti-aging peptide claim.
(11:11) Which topical peptides have more evidence behind them.
(13:01) Why neuropeptides are not really “Botox in a bottle.”
(15:54) What to know about using peptide products with vitamin C, retinoids, and other actives.
(17:46) Why pH, concentration, and the other ingredients in a formula can affect peptide stability.
(21:14) What actually makes a topical peptide product more likely to work.
(22:45) Why healthy skin function still matters when you are trying to support collagen and repair.
(25:09) If you could only add one peptide product to your routine, which type should it be?
Listen to this episode of Biohacking Beauty before another peptide claim on a skincare label convinces you to spend more without knowing what is actually inside the formula.
Previous Episodes Mentioned:
Nathalie Niddam: Peptides, Bioregulators, and the Truth About Skin Longevity
Nathalie Niddam: The Potential of Peptides in Skin Health and Anti-Aging
Peptides episodes to watch:
Peptides, Bioregulators & The Truth About Skin Longevity | Nathalie Niddam:
:https://www.youtube.com/watch?v=2AoqcXJ_MMc
Why Peptides Are Not the Shortcut Biohackers Think They Are with Chris Duffin:https://www.youtube.com/watch?v=UNPhDZXY6kw
Peptides, Hormones, and the Anti-Aging Protocol Most Women Start Too Late:https://www.youtube.com/watch?v=b_CTcFjeyqQ&t=428s
GHK-Cu Explained: The Copper Peptide That Signals Collagen Repair:https://www.youtube.com/watch?v=qGDNyVtZjl4
Find more from Young Goose:
Website:Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Wed, 07 Oct 2026 - 25min - 272 - 273. Dr. Staci Whitman: The Surprising Oral Causes Behind Facial Asymmetry and How Your Face Ages | Part 2
You probably know which side of your face you prefer in photos. One jawline may look sharper. One cheek may sit differently. One under-eye may look darker. And while some facial asymmetry is completely normal, the way you use your mouth can also influence how the two sides of your face function over time.
In Part 2 of our conversation with Dr. Staci Whitman, we look at facial aging from inside the mouth. We get into how one-sided chewing, bite patterns, tongue function, palate width, airway health, and jaw structure can influence facial symmetry and the way changes become visible in the face. We also explore what adults can realistically do when the issue is structural rather than purely cosmetic. Dr. Staci breaks down the conversations happening around mastic gum, myofunctional therapy, palate expansion, MARPE, oral appliances, and tongue-tie releases, including why changing the way the mouth functions is much more complicated than trying the latest jawline trend online.
Dr. Staci Whitman is a board-certified pediatric dentistandFunctional Medicine Certified Practitioner whose work focuses on functional dentistry, airway health, craniofacial development, the oral microbiome, and the mouth-body connection. She is the co-founder of the Institute for Functional Dentistry and founder of Bloom + Brighten.
What’s Discussed:
[1:37] Why persistent dark under-eyes may sometimes point to airway issues, inflammation, and facial structure rather than pigmentation alone.
[3:32] What happens to the jaw and the bones supporting the face as we age.
[6:44] How chewing predominantly on one side may contribute to differences between the two sides of the face.
[10:55] What your chewing patterns, saliva, and cavities may reveal about how you are using your mouth.
[17:09] Whether mastic gum and jaw exercises can actually change the appearance of an adult face.
[20:00] How tongue function, swallowing, and breathing are addressed through myofunctional therapy.
[21:50] Why a narrow palate may require more than simply changing your tongue position.
[22:30] What adults should know about palate expansion, MARPE, and oral appliances.
[31:26] Why finding a tongue tie does not automatically mean releasing it is the first step.
[40:49] Who to see when you suspect your bite, tongue, airway, or jaw function may be affecting your face.
Listen to this episode of Biohacking Beauty to learn why facial asymmetry may be giving you clues about what is happening inside your mouth.
Find more from Young Goose:
Website:www.younggoose.com/
Use code PODCAST10 to get 10% OFF your first purchase, and if you are a returning customer use code PODCAST5 to get 5% OFF.
Instagram:@young_goose_skincare
Find more from Dr. Staci Whitman:
Website:doctorstaci.com
Instagram: @doctor_staci
TikTok:@doctor_staci
YouTube: youtube.com/channel/
Book:SPIT: Why Your Mouth-and Its Microbes-Are the Secret to Whole-Body, Lifelong Health
Read Dr. Staci’s newsletter:substack.com/@doctorstaci
Resources
Find an oral-systemic health practitioner through AAOSH: aaosh.org/find-a-practitioner
Search the IAOMT directory for a biological dentist or health professional: iaomt.org/for-patients/Search/?ppage=dashboard
Find an airway-focused practitioner through AAPMD:aapmd.org/find-aapmd-professional
Search The Breathe Institute provider directory: breatheops.com/directory/the-breathe-institute
Learn more about the Institute for Functional Dentistry:functionaldentistry.org/
Wed, 30 Sep 2026 - 45min - 271 - 272. Dr. Staci Whitman: The “Harmless” Oral Habits That Could Be Reshaping Your Face and Aging Your Skin | Part 1
You can invest in your skincare, protect your collagen, and do everything you can to age well, while completely overlooking something that sits only a few inches away from your skin: your mouth. The way you breathe, chew, swallow, care for your gums, and support your oral microbiome can influence far more than your teeth.
In this episode of Biohacking Beauty, we sit down with Dr. Staci Whitman to explore how oral health connects to facial structure, airway health, under-eye darkness, inflammation, blood flow, and the appearance of your skin. We also get into the everyday oral habits that may be working against you, what actually matters in an oral routine, and the facial signs that can make Dr. Staci suspect something deeper is going on.
Dr. Staci Whitman is a board-certified pediatric dentist and Functional Medicine Certified Practitioner who specializes in the mouth-body connection, airway development, craniofacial growth, and the oral microbiome. She is the co-founder of the Institute for Functional Dentistry and founder of Bloom + Brighten, bringing functional medicine and systems biology into a part of health that is still often treated separately from the rest of the body.
What’s Discussed:
(01:17) Why humans chew dramatically less today and what that can mean for facial development.
(05:57) How mouth breathing, narrow airways, and modern eating habits can show up in the face.
(11:23) The oral bacteria involved in nitric oxide production and why blood flow matters for skin.
(13:02) Why saliva is one of the most overlooked parts of oral health and what happens when your mouth stays dry.
(16:50) Why Dr. Staci believes dentistry is missing a major piece of the longevity conversation.
(24:20) What actually matters in an oral-health routine, from meal timing and nasal breathing to flossing and microbiome testing.
(31:40) How hormones, pregnancy, perimenopause, and menopause can change oral health.
(40:52) What tongue scraping actually does and what your tongue may reveal about your health.
(46:02) What Dr. Staci notices about your face, eyes, lips, posture, and breathing before she even looks at your teeth.
Listen to this episode of Biohacking Beauty to learn why the way your face looks may be influenced by habits you have never considered part of your beauty routine.
Find more from Young Goose:
Website:www.younggoose.com/
Use code PODCAST10 to get 10% OFF your first purchase, and if you are a returning customer use code PODCAST5 to get 5% OFF.
Instagram:@young_goose_skincare
Find more from Dr. Staci Whitman:
Website:doctorstaci.com
Instagram: @doctor_staci
TikTok:@doctor_staci
YouTube:youtube.com/channel/
Book:SPIT: Why Your Mouth-and Its Microbes-Are the Secret to Whole-Body, Lifelong Health
Wed, 23 Sep 2026 - 54min - 270 - 271. Dr. Mamina Turegano: What Your Skin Reveals About Your Health, Aging & Hormones
Most of us assume that if something serious was happening inside our body, we would know. We would feel sick. Something would hurt. A blood test would catch it. But some health problems can develop quietly for years, and sometimes the clue that finally gets your attention is sitting right where you can see it: on your skin.
In this episode of Biohacking Beauty, we get into the skin changes that can point to something happening beyond the surface, from psoriasis and multiple skin tags to persistent rashes, hair loss, and subtle signs of skin cancer. We also talk about what makes a dermatologist look deeper, how long sun damage can build before it becomes visible, and when a skin concern deserves more than another product or treatment.
Dr. Mamina Turegano is a triple board-certified dermatologist, internist, and dermatopathologist, giving her a unique perspective that connects what is happening on the skin with what may be happening throughout the body. Her background in internal medicine and dermatopathology allows her to look beyond the appearance of a skin change and consider the metabolic, autoimmune, inflammatory, and systemic conditions that may be connected to it.
What’s Discussed:
(01:25) Why you can feel perfectly healthy while something is already changing internally.
(02:48) Why psoriasis can warrant looking at cardiovascular and metabolic health too.
(04:49) What multiple skin tags may tell you about insulin resistance.
(16:07) When an unexplained rash or chronic itching deserves a deeper workup.
(19:18) The skin cancer signs people may overlook and when hair loss needs more attention.
(23:14) How sugar, alcohol, stress, sleep, and circadian disruption can accelerate skin aging.
(35:31) Why Dr. Mamina is comfortable with topical peptides but not injectable peptides yet.
(45:24) Whether Google, AI skin scanners, and self-diagnosis are helping or hurting.
(48:53) How long sun damage may be building before you finally see it.
Listen to this episode of Biohacking Beauty to learn which skin changes are worth paying closer attention to, and why treating what you see is not always the end of the conversation.
Resources mentioned:
Want to find out more about Autophagy?
Listen here: The Overlooked Side of Autophagy Causing Aging - Part 1
The Overlooked Side of Autophagy Causing Aging - Part 2
Find more from Young Goose:
Website:younggoose.com
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use code PODCAST5 to get 5% OFF.
Instagram:@young_goose_skincare
Find more from Dr. Mamina Turegano:
Website: DrMamina.com
Instagram: @dr.mamina
TikTok: @dr.mamina
YouTube: @dr.mamina
Wed, 16 Sep 2026 - 57min - 269 - 270. Your Most-Asked Skincare Questions, Answered With Science
Social media has made skincare information easier to access than ever. One video can convince you to increase your retinol. Another influencer can tell you an ingredient is “toxic.” Then someone else swears your skin has stopped responding because you have used the same product for too long.
But think about what that can do to your skin when you follow every new rule without understanding what the product is actually doing. More stimulation is not always better. “Clean” does not automatically mean effective. A rosacea flare is not always something another soothing serum can fix. And moving to a stronger retinol just because your current one feels less intense may be the wrong move entirely.
In this Biohacking Beauty Class, we are answering the skincare questions our community keeps asking and unpacking the advice that sounds simple online but becomes much more complicated once you understand how skin actually responds. We also get into collagen supplements and share a few of the new Young Goose products and technologies we have been working on behind the scenes.
What’s Discussed:
(02:25) Can your skin actually get used to skincare products?
(07:44) Why “clean skincare” does not automatically mean better skincare.
(16:20) What may be driving rosacea when nothing seems to help.
(19:09) Why stronger retinol is not always the smarter next step.
(25:29) Do collagen supplements actually help your skin?
(30:10) The new cleanser and eye product coming to Young Goose.
(34:28) The new skincare technology we are testing in ampule form.
Listen to this episode of Biohacking Beauty before the next skincare tip on your feed convinces you to change something that may not need changing at all.
And before you go, we have a little listener bonus.
If you want to receive a product from us, leave us a review on Apple Podcasts. That is all you have to do.
If we read your review out loud on the podcast, we will send you a product in the mail. So leave us a review, make it cute, make it honest, and you might hear it in an upcoming Biohacking Beauty Class episode.
Find more from Young Goose:
Website:Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Wed, 09 Sep 2026 - 33min - 268 - 269. Cynthia Thurlow: What Midlife Gut Changes Have To Do With Your Skin
When your skin starts changing in midlife, it is easy to assume the products that used to work suddenly stopped working. And when changing the routine does not fix it, hormones usually get the blame.
But there is another shift happening at the same time that rarely gets brought into the skin conversation: your gut. In this episode of Biohacking Beauty, we get into what starts changing in the gut through perimenopause and menopause, the surprising ways those changes can show up far beyond digestion, and why some of the health strategies women swear by before 40 may need to be reconsidered later.
Cynthia Thurlow is a nurse practitioner, host of the Everyday Wellness podcast, author of The Menopause Gut, and an international speaker with more than 25 years of experience in women’s health, metabolic health, perimenopause, menopause, and intermittent fasting.
What’s Discussed:
(04:01) The health crisis that changed the way Cynthia understood midlife health.
(19:12) The gut-hormone connection most women do not know exists.
(23:14) What changes when estrogen, immunity, and the gut start shifting together.
(29:13) The early signs that progesterone may be changing.
(35:49) What your gut may have to do with ovarian and mitochondrial aging.
(41:46) The part of longevity Cynthia thinks we are seriously underestimating.
(47:54) Why Cynthia changed her own approach to intermittent fasting after 40.
Listen to this episode of Biohacking Beauty to learn what midlife gut changes may have to do with your skin, and why the answer may go much deeper than changing your skincare routine.
Find more from Young Goose:
Website: Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Find more from Cynthia Thurlow:
Twitter: @_CynthiaThurlow
Instagram: @cynthia_thurlow_
LinkedIn: cynthia-thurlow
YouTube: cynthiathurlow
Website: cynthiathurlow.com/
The Midlife Pause supplements: themidlifepause.com
Wed, 02 Sep 2026 - 52min - 267 - 268. 10 Habits for Younger Skin That Have Nothing To Do With Skincare
Everyone wants skin that looks brighter, firmer, smoother, and healthier for longer.
But sometimes the thing holding your skin back is not the serum you forgot to buy. It is the blood sugar spike you keep missing, the protein you are not getting enough of, the sleep window you keep pushing, the strength training you keep delaying, or the daily stress your skin has to keep recovering from.
In this Biohacking Beauty Class episode, we are talking about the habits we actually use to support skin health outside of skincare. We get into the choices that help your skin repair better, age slower, respond better to treatments, and build the kind of foundation no product can fully replace.
What’s Discussed:
(03:10) The dessert rule that helps reduce daily sugar exposure.
(05:37) Why fiber matters beyond digestion.
(06:26) What a glucose monitor can show you about foods that look “healthy.”
(08:04) Why lifting weights can change how your skin looks over time.
(10:13) What protein and micronutrients have to do with collagen support.
(11:24) How morning sunlight, sleep, and circadian rhythm connect to skin repair.
(16:16) Where red light therapy, antioxidants, and consistency fit into the bigger skin longevity picture.
Listen to this episode of Biohacking Beauty to learn the habits we swear by when we want our skin to have more to work with than skincare alone.
And before you go, we have a little listener bonus.
If you want to receive a product on us, leave us a review on Apple Podcasts. That is all you have to do.
If we read your review out loud on the podcast, we will send you a product in the mail. So leave us a review, make it cute, make it honest, and you might hear it in an upcoming Biohacking Beauty Class episode.
Find more from Young Goose:
Website:Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Wed, 26 Aug 2026 - 19min - 266 - 267. Dr. Amie Hornaman: The Thyroid Mistake That Keeps Women From Getting Answers
Thyroid dysfunction is often treated like it is easy to rule out. You ask for labs, your doctor checks TSH, and if that one marker is not flagged, you are told your thyroid is fine.
But what if that is the problem?
In this episode of Biohacking Beauty, we sit down with Dr. Amie Hornaman to unpack what most thyroid conversations skip: the difference between being “normal” on paper and having enough active thyroid hormone available to your cells. She explains why TSH is not a thyroid hormone, why T4-only medication may not be enough for many people, and why women can keep struggling even after being told their thyroid is not the issue.
Dr. Amie is known as The Thyroid Fixer, a functional medicine doctor, host of The Thyroid (and Hormone) Fixer podcast, founder of the Advanced Thyroid and Hormone Clinic, and author of The Thyroid Fix. After being misdiagnosed by six different doctors, she built her practice around helping patients get the answers conventional medicine often misses.
What’s Discussed:
(01:22) Why so many women feel like their body is rebelling against them.
(04:32) Why the diagnosed hypothyroidism number may not reflect the real problem.
(07:11) The difference between being undiagnosed, undertreated, and mistreated.
(10:54) Why skin aging after 40 is not only an estrogen conversation.
(14:22) How quickly thyroid and hormone changes can show up in the skin.
(20:57) Why skin aging needs an inside-out and outside-in approach.
(28:35) What markers belong on a full thyroid panel beyond TSH.
(30:55) Why free T3, reverse T3, and thyroid antibodies matter.
(38:48) What thyropause is and why it can overlap with perimenopause and menopause.
(45:01) A one-morning plan to support thyroid, insulin, protein, sleep, and skin health.
Listen to this episode of Biohacking Beauty to understand why your thyroid labs may not be telling the whole story, and why your skin, hair, metabolism, mood, and energy may be showing what one marker missed.
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Find more from Dr. Amie Hornaman:
Website: dramie.com
Instagram: @dramiehornaman
Podcast: dramie.com/podcast/
Wed, 19 Aug 2026 - 55min - 265 - 266. Q&A: Your Questions Answered on Exosome Skincare (Everything You Need To Know Before You Try)
Exosomes have become one of the most talked-about ingredients in advanced skincare, but the conversation around them can get confusing fast. Some people hear “cellular messaging” and worry about DNA. Others see plant exosomes, stem cell claims, growth factors, or vampire facial comparisons and assume all exosome products are working the same way.
The problem is that the word “exosome” does not tell you enough. Exosomes are messengers, and the message depends on the source. A plant-derived exosome, a mesenchymal-derived exosome, and a platelet-derived exosome are not carrying the same type of signal for the skin. So before you trust the trend, it helps to understand what kind of message your skin is actually receiving.
In this Biohacking Beauty Q&A, we break down the biggest questions listeners have been asking about exosomes. We get into why exosomes do not change your DNA, what microRNA messaging means, why consistency matters, how plant exosomes compare to human-derived options, why platelet-derived exosomes may be especially relevant for skin repair, and what makes Vampire Exosomes® different from other exosome serums.
What’s Discussed:
03:05 Whether exosomes can change your DNA or transfer genetic material.
07:08 How exosomes work through microRNA messaging instead of changing your genome.
09:21 Why exosome messages do not stick around forever and need consistency.
11:02 Where exosomes come from and why the source of the message matters.
13:45 Why plant exosomes may offer some benefits, but may not be the strongest fit for skin repair.
21:34 How mesenchymal-derived and platelet-derived exosomes differ in their relationship to skin repair.
27:29 What makes Vampire Exosomes® different from other exosome serums, including dose, NAD support, barrier support, and batch verification.
32:25 How Vampire Exosomes® compares to a vampire facial and why topical exosomes work differently.
Listen to this episode of Biohacking Beauty to understand what exosomes actually are, what questions to ask before buying an exosome product, and why the source, dose, formula, and proof matter as much as the word “exosome” itself.
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Young Goose Vampire Exosomes® https://www.younggoose.com/products/vampire-exosomes
Instagram: @young_goose_skincare
Wed, 12 Aug 2026 - 39min - 264 - 265. Anastasia (Beauty Fascia) Part 2: The Hidden Cost of Fillers, Botox, and Skin Tightening Devices
A lot of beauty treatments are sold around the result people want most: tighter skin, fewer lines, more volume, and a face that looks refreshed without going under the knife.
And because these treatments have become so common, it can feel like the decision is simply about when to start, who to go to, or which device or injectable will give the most natural-looking result.
But Anastasia looks at the face through a different lens. In Part 2 of this conversation, she challenges the idea that a visible result is the only thing worth paying attention to. She brings the conversation back to the tissue underneath the skin, the movement of the face, how the body responds, and what people may want to question before choosing treatments that promise to tighten, fill, freeze, or stimulate the face.
What’s Discussed:
35:15 Why tightening devices are often positioned as an alternative to plastic surgery.
36:55 What people may want to consider before choosing treatments that rely on stimulation or controlled damage.
41:51 Why the risks of beauty shortcuts are not always obvious at first.
45:24 What to know about training, devices, and the person performing the treatment.
51:15 What Anastasia wants people to think about before getting fillers.
53:53 Why the body’s response to fillers deserves more attention.
1:02:47 Why preventative Botox deserves a deeper conversation than wrinkle prevention.
1:12:21 Where Anastasia lands on sun exposure, SPF, and skin protection.
1:19:43 What she wants women to start questioning about beauty, aging, and the tissue underneath the skin.
Before choosing the next treatment that promises to lift, tighten, smooth, or freeze time, this conversation asks you to slow down and look at what may be happening beneath the result.
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Find more from Anastasia:
Website: BeautyFascia.com/
Instagram: @anastasiabeautyfascia
Wed, 05 Aug 2026 - 53min - 263 - 264. Anastasia (Beauty Fascia) Part 1: Do Red Light Masks, Gua Sha, and Facial Devices Actually Work?
Red light masks, facial sculpting devices, gua sha tools, and at-home lifting treatments are everywhere. And when a tool promises less puffiness, a sharper jawline, or younger-looking skin, it is easy to believe the right device could finally create the change you have been looking for.
But a face is not a collection of surface-level problems. The way it looks and ages is also influenced by muscle tension, facial structure, breathing patterns, soft tissue, posture, and how fluid moves through the tissue. So when a beauty tool does not create the result you expected, the problem may be that the tool was never addressing what was actually driving the change.
Anastasia, a board-certified Structural Integration Therapist and founder of Beauty Fascia, returns to explain what she looks at beyond skin appearance and what some of the biggest at-home beauty trends can realistically do. She shares why she prefers a red light panel over a mask, where facial devices may fall short, when gua sha can help, and why doing more is not always better for the skin.
What’s Discussed:
03:13 What Anastasia looks at beyond wrinkles and skin appearance.
04:35 How facial structure, muscle tension, breathing, and fluid flow influence the way the face looks.
09:02 Why Anastasia prefers a red light panel over a mask.
10:04 What to consider before spending money on a red light device.
17:54 Why buying a beauty tool does not automatically create a self-care habit.
23:56 What at-home facial devices can realistically change.
28:48 When gua sha may help, why under-eye bags are not always a lymphatic problem, and how overdoing it can backfire.
Before investing in another device or adding another technique to your routine, it helps to know what problem you are actually trying to solve and whether the tool was designed to address it.
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Find more from Anastasia:
Website: BeautyFascia.com/
Instagram: @anastasiabeautyfascia
Wed, 29 Jul 2026 - 37min - 262 - 263. Q&A: The Skincare Trends Worth Questioning Before You Buy
Skincare trends are moving fast, and it can be hard to tell what is actually worth your attention. One day everyone is talking about red light masks, then peptide lip balms, at-home microneedling, men’s skincare, acne protocols, or another product claiming to be the next thing your skin needs.
The problem is that some of these tools can be useful, but the way they are marketed often leaves out the context that matters most. A red light device is not just about wavelength. Acne is not just about bacteria. Peptides in skincare are not automatically effective just because the word is on the label. And not every trend deserves to become the center of your routine.
In this Q&A episode of Biohacking Beauty, we’re answering the skincare questions you sent in and breaking down what to look at before buying into the hype. We get into acne, red light therapy masks, at-home microneedling, men’s skincare, and the peptide skincare problem so you can think about these trends with more science and less noise.
What’s Discussed:
(03:14) Why acne is not just a bacteria problem.
(07:24) What to know before buying a red light therapy mask.
(13:36) The red light devices we actually use at home.
(16:06) At-home microneedling, skin barrier risk, and where to draw the line.
(21:02) Why men’s skincare is mostly marketing.
(25:10) What performance skincare may actually mean.
(29:41) Why peptide skincare claims are harder to verify than they seem.
Listen to this episode of Biohacking Beauty to understand which skincare trends deserve a closer look, what questions to ask before buying, and where the science matters more than the marketing.
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Wed, 22 Jul 2026 - 33min - 261 - 262. Chris Duffin: The Peptide Mistake That Keeps Regenerative Protocols From Working
Peptides are being treated like the missing piece in recovery, skin longevity, fat loss, performance, and aging. The usual belief is that if you find the right compound, the right dose, or the right stack, the body will finally respond the way you want it to. But what if the protocol is not the first thing that needs to be fixed?
In this episode of Biohacking Beauty, I sit down with Chris Duffin to unpack what most peptide conversations skip: the state of the body receiving the signal. They get into why cellular terrain matters, what happens when people chase regenerative tools before the foundation is ready, and how skin can reveal whether the body is actually prepared to adapt, repair, and age well.
Chris Duffin is the Human Performance Expert, an internationally recognized authority in human performance science, and the first person in history to squat and deadlift over 1,000 pounds for multiple reps. His work sits at the intersection of strength, resilience, peptide science, executive performance, and regenerative health, which makes this conversation a rare look at what it actually takes to build a body that can respond to advanced tools instead of just relying on them.
What’s Discussed:
(02:15) Why peptides are powerful, but not the whole answer.
(05:12) What cellular terrain has to do with regeneration.
(09:18) Why looking healthy does not always mean the body is resilient.
(15:07) How peptides fit into a bigger recovery and longevity strategy.
(27:09) What peptide reactions may reveal about the body underneath.
(50:06) Why skin rejuvenation depends on the body’s ability to respond.
(01:06:05) How peptide hype is changing the longevity conversation.
Listen to this episode of Biohacking Beauty to understand what needs to happen inside the body before peptides, procedures, or any regenerative tool can actually move the needle.
Resources Mentioned:
Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/
FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Find more from Chris Duffin:
Instagram: @mad_scientist_duffin
Website: enhancedexecutive.com/
Wed, 15 Jul 2026 - 1h 10min - 260 - 261. Reacting To Allure’s LED Mask Advice: What To Know Before Spending Money On a LED Mask
If you have been thinking about buying a LED mask, the hardest part is knowing what actually matters. The price range is all over the place, every brand seems to have some version of “FDA cleared” on the page, and a lot of the buying advice sounds scientific enough to trust. But none of that automatically tells you whether the device is strong enough to do anything meaningful for your skin.
That is why we wanted to take a closer look at an Allure post called So You Wanna Buy a LED Mask. The guide brings up the same things people usually look at before buying one: price, number of bulbs, FDA clearance, clinical trials, and how often you have to use it. Some of those details can be useful, but they can also distract from the real questions: how much light does the device actually deliver, what wavelengths does it use, and is the coverage strong enough to create meaningful stimulation?
That matters if you are about to spend a few hundred dollars on a device and you are using the wrong signals to decide. A high price, FDA clearance, or a small clinical study can make a mask sound more credible, but those details do not always answer the question you actually care about: Will this device give my skin enough stimulation to be worth using?
What’s Discussed:
(04:22) Why we are reacting to Allure’s LED mask buying guide.
(05:12) Why the $100 to $1000 LED mask price range is not very helpful.
(07:31) Why diode count matters, but output matters more.
(08:33) Whether you actually need to use a LED mask every day.
(10:55) What FDA clearance does and does not tell you.
(13:35) Why a five-subject clinical trial is not strong proof.
(15:45) The wavelengths that matter for red light therapy.
Listen to this episode of Biohacking Beauty to understand what actually matters before buying a LED mask, and why the most scientific-sounding claims are not always the ones that tell you if a device will work.
Resources Mentioned:
Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/
FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Wed, 08 Jul 2026 - 19min - 259 - 260. Dr. Jennifer Berman: Peptides, Hormones, and the Anti-Aging Protocol Most Women Start Too Late
We have been getting the same question in our DMs for months now. Peptides are everywhere. Everyone is talking about them. But what actually has evidence behind it, what is hype, and where do hormones fit into all of this? So we went and found someone who has been living this conversation for 35 years, not just talking about it.
Dr. Jennifer Berman is a urologist, New York Times bestselling author, and one of the leading voices in female sexual and menopausal health. She pioneered the field at UCLA, runs the Berman Women's Wellness Center in Beverly Hills, and has been her own first patient through every transition she now treats. She is the kind of doctor who was doing things a decade before they became mainstream and has the clinical receipts to back all of it up.
In this episode we get into why peptides are the missing piece of the menopause puzzle, what hormones are really doing to your skin from the inside out, and how treatments that were written off as fringe became the new gold standard for longevity.
What's Discussed:
(01:42) Why peptide production declines with age and what that actually means for how women look and feel in perimenopause.
(04:04) The regulatory reality around peptides right now and why medical grade from a 503B pharmacy is the only route worth taking.
(06:07) The specific peptides with the strongest evidence for skin, muscle, fat loss, recovery, and cognitive function.
(13:12) Why your mid to late 30s is already perimenopausal by definition and why that changes when you start.
(15:02) C-Link, C-Max, and PE22-28 for mood, neuroplasticity, and cognitive protection and why Dr. Berman stacks them together.
(39:17) The exact point where topical skincare stops being enough and what hormone imbalance is doing to skin that no cream can fix.
(53:08) Why cycling your peptides matters, what receptor attenuation actually is, and why the protocol on your feed is not a clinical protocol.
By the end of this episode you will know which peptides have actual evidence behind them, where topical skincare stops working without hormonal support, and what an inside-out longevity protocol looks like from a doctor who has lived every transition she treats.
Resources Mentioned:
Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/
FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Find more from Dr. Jennifer Berman:
Website: bermansexualhealth.com/
Instagram: @jenbermanmd
Wed, 01 Jul 2026 - 1h 05min - 258 - 259. Dr. Dan Pardi: How Creatine Supports Brain Function, Skin Health, and DNA Repair
Creatine has been boxed in as a gym-bro supplement for decades, but the latest research shows it's doing far more than building muscle. It buffers brain energy under sleep deprivation, supporting bone density and mood stability through perimenopause, and freeing up methyl groups for detoxification and DNA repair.
We dive deeper into this in the Biohacking Beauty Podcast with Dr. Dan Pardi. We also chat about why the bloating myth is backwards, how creatine and NAD work synergistically to support mitochondrial energy, and what topical creatine could mean for the future of skincare.
Dr. Dan Pardi is a researcher whose first study in the 1990s focused on creatine, and he has spent three decades following the science as it expanded from sports performance into brain health, healthspan, and women's physiology. He is the Chief Health Officer at Qualia Life Sciences, where the team has earned recognition from the Nutrition Business Journal for science and innovation.
His work focuses on translating peer-reviewed research into formulations that support cellular energy, methylation, and longevity.
Let's dive in.
Use code YOUNGGOOSE at https://www.qualialife.com/ for a special discount.
What's Discussed:
(4:32) Why creatine went from a niche Olympic edge to a billion-dollar category after the 1992 Games.
(11:18) The sloping-surface analogy that explains why 5 grams saturates muscle but barely touches the brain.
(15:47) How creatine buffers cognitive performance under sleep deprivation, with no decrement at baseline.
(22:05) Why the bloating myth is backwards and what intracellular hydration actually feels like.
(28:40) Topical creatine, the dermal layer, and why molecule size matters for skin delivery.
(36:22) The decade of creatine in women: bone density, mood, and energy fluctuations through menopause.
(42:15) Where the hair loss rumor really came from, and why creatine took the blame.
(51:08) Why 40% to 70% of your body's methylation goes to making creatine, and what that means for NAD stacking.
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Find more from Dr. Dan Pardi:
Instagram: @drdanpardi
Substack: @drdanpardi
Find more from Qualia:
Website: qualialife.com
Instagram: @qualialife
Qualia Creatine: qualialife.com/shop/qualia-creatine
Wed, 24 Jun 2026 - 51min - 257 - 258. SPF Is Not Enough: The Cellular Repair Protocol Your Skin Needs This Summer
When summer skin starts looking dull, congested, tired, or slower to recover, it is easy to blame the obvious things: heat, sweat, sunscreen, long days outside, or the wrong moisturizer. So the conversation usually stays on the surface. Use SPF. Cleanse better. Switch to lighter products. Add antioxidants. But before we treat summer skin like another product problem, there is a deeper question worth asking: what is the sun doing to the cell before you ever see the damage in the mirror?
In this episode of Biohacking Beauty, I want to take the sun conversation past burns, wrinkles, and dark spots. I’m walking through what UV exposure does to the systems your skin depends on to keep up with summer: cellular energy, NAD, mitochondrial function, and DNA repair. Because the skin does not only need protection from the sun. It also needs enough repair capacity to deal with the damage that gets through.
Young Goose's Skin Under the Sun campaign is active from June 15 through June 28 at younggoose.com
What’s Discussed:
(01:50) The light-activated repair tool humans lost.
(06:10) Why NAD matters for skin energy and repair.
(10:15) How UV exposure increases oxidative stress and disrupts NAD supply.
(16:44) What UV-induced DNA lesions are and why CPDs matter.
(22:21) Why L.A.D.R. serum was built around light-activated repair-inspired science.
(31:52) Why the sun is one of the biggest controllable inputs into biological skin aging.
(35:43) The five protocol-level moves for supporting skin through summer.
Listen to this episode of Biohacking Beauty to understand what UV is doing under the surface and how to build a smarter summer protocol around protection, energy, and repair.
Resources Mentioned:
Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/
FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Wed, 17 Jun 2026 - 39min - 256 - 257. The Mitochondria Problem Behind Aging Skin + How to Recharge Your Skin and Look Younger
Every fibroblast inside your dermis right now is asking 200 to 2,000 mitochondria to power its work in real time, and those mitochondria are descendants of a free-living bacterium swallowed by a larger cell 2 billion years ago. As you age, those mitochondria run slower and your cells build fewer of them to replace the ones that fail.
In this solo episode, Young Goose co-founder Amitay Eshel breaks down the two sides of mitochondrial decline that drive skin aging and explains why the science-led skincare category has spent the last decades addressing only one of them.
The first side of skin aging is where most skincare brands have built their products around. The other side is the one almost no skincare on the market is formulating for, and it is where the next chapter of skin longevity is being written.
If you have outgrown the antioxidant-and-peptide era of skincare and want to understand what is actually happening underneath your skin as it ages, this episode is for you.
What's Discussed:
(01:35) The 2-billion-year-old contract inside every skin cell that is now fraying.
(04:10) Why skin is one of the most mitochondria-dense organs in your body.
(08:20) The 2012 paper that showed NAD drops by half between 35 and 70.
(13:15) How a refugee fired in 1933 figured out the chemistry your cream still runs on.
(16:30) The second half of the decline almost no skincare addresses.
(19:45) The master regulator that decides whether your cells can hire.
(24:00) The two columns of mitochondrial biology and why most brands only work in one.
(32:10) Why this is a ten-year strategy, not a two-week one.
Resources Mentioned:
Download the Cellular Energy Protocol: https://www.younggoose.com/pages/the-mitochondrial-skin-stack
Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/
FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Wed, 10 Jun 2026 - 34min - 255 - Dr. Tyler Panzner: Hidden Trade-Offs of Longevity Supplements and the Advantage of Topical Delivery
Roughly 25% to 30% of the population carries slow variants in the MAOA or COMT genes, the two enzymes responsible for clearing adrenaline, dopamine, and serotonin from the brain.
For these individuals, common polyphenols marketed for inflammation and longevity, including curcumin, act as weak MAOA inhibitors that further slow neurotransmitter breakdown. The result is a quiet buildup of stimulation that gets misread as anxiety, insomnia, or unexplained agitation, with no obvious connection to the supplement bottle that caused it.
In this episode of Biohacking Beauty, Dr. Tyler Panzner joins us to translate exactly this kind of pharmacological nuance into protocols people can actually use. He is a PhD pharmacologist with research in neuropharmacology and breast cancer metastasis, and has worked with over 900 clients, particularly highly sensitive people, to identify their genetic weak points and remove the supplements quietly working against them.
If you are stacking longevity supplements, feel wired without explanation, or want to understand why your body responds differently than the marketing promises, this episode is for you.
What's Discussed:
03:15 Why supplements are the "Wild West" of holistic health.
08:42 The hidden problem with curcumin, resveratrol, and EGCG for sensitive people.
15:30 The four gas pedals of the brain: adrenaline, histamine, glutamate, and sulfur.
22:18 Stress vs. anxiety and how the brain builds narratives around physiological activation.
29:45 Why your meditation practice may be failing because of a supplement.
37:20 NMN degradation, the NAMPT "toll booth," and topical vs. systemic delivery.
46:08 The future of multi-omics testing and personalized protocols.
Find more from Young Goose:
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at younggoose.com
Instagram: @young_goose_skincare
Find more from Dr. Tyler Panzner:
Website: drtylerpanzner.com
Instagram: @drtylerpanzner
Facebook: Dr. Tyler Panzner
Linkedin: Tyler Panzner, Ph.D.
YouTube: @drtylerpanzner
FREE Guides: drtylerpanzner.com/free-guides
1:1 Genetic Coaching: https://drtylerpanzner.com/startyourjourney
Quieting an Overactive Mind Webinar: https://overstimulated.drtylerpanzner.com/webinar-registration-page
Wed, 03 Jun 2026 - 1h 09min - 254 - The Death of Anti-Aging Skincare & The Longevity Framework That Replaces It
Your skin has a biological age and for most people, it's not the same as their chronological one. Mayo Clinic published the SkinSpan framework this year specifically to quantify it, and the 12 Hallmarks of Aging now have a direct application to dermal tissue.
This raises an uncomfortable question: if you're already optimizing everything below the neck with NAD IVs, peptides, and red light, why is the skincare on your face still operating on a paradigm from 1987?
In this new episode of the Biohacking Beauty Podcast, we give you a preview of the keynote we're delivering at Dave Asprey's Beyond Conference and walk you through the 3-pillar framework that replaces traditional anti-aging skincare with longevity science in mind.
Because the results you can feel today and results you can measure in ten years are not the same thing. And we think you deserve both.
Let's dive in.
What's Discussed:
(2:29) The gap no one in longevity talks about.
(3:06) Why your moisturizer is 38 years behind your supplements.
(6:21) The 12 Hallmarks of Aging, decoded.
(9:42) Pillar 1: The master pathway of skin aging.
(12:18) Why NAD in a jar doesn't work (and what does).
(14:22) The cellular housekeeping system that quietly shuts down with age.
(15:17) The peptide that affects 32% of your skin's genome.
(16:55) Pillar 2: The software updates your cells stop sending.
(20:09) The PRP lineage that changed regenerative aesthetics.
(22:54) Pillar 3: The pillar our community doesn't want to hear about.
(29:09) The protocol, tiered by where you're starting.
(37:55) How Young Goose fits into what you're already doing.
(40:32) The two tests we're building to measure skin longevity.
Find more from Young Goose:
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareHead to younggoose.com/products/youth-body-cream for 20% offFri, 29 May 2026 - 45min - 253 - The Overlooked Side of Autophagy Causing Aging - Part 2
The melanocytes giving pigment to your skin right now might be older than your car. They have been sitting in your dermis for decades, and unlike the cells on your skin's surface, they do not get replaced. They have to keep themselves clean which happens through autophagy.
In Part 2 of our autophagy deep dive, we get specific about how skin handles autophagy differently from other parts of the body. We unpack why long-lived cells like fibroblasts and melanocytes depend on this cleanup process, what happens when it fails, and how it ties directly to gray hair, hyperpigmentation, sagging skin, and that brownish dullness no serum seems to fix.
We also introduce one of the most overlooked players in this entire conversation, and explain why we believe it is the next NAD. If you want to understand what is actually happening underneath your skin as it ages, and what tools we have to intervene at the cellular level, this episode is for you.
What's Discussed:
(01:06) Why skin needs autophagy more than almost any other organ(03:07) The cells on your face that may be older than your car(04:25) The 2013 paper that linked autophagy failure to dermatitis(08:44) Zombie mitochondria and why photo-aged skin makes bad collagen(12:25) Senescent cells, SASP, and how a few bad cells poison the dermis(18:38) The 2019 Drexel rapamycin trial that proved this works in humans(23:22) The 2024 spermidine study that changes how we think about autophagy(29:51) Why your skin barrier collapses without this one moleculeResources Mentioned:
Biohacking Beauty Podcast with Dr. Scott Sherr: Stress & Light on Your Skin Are Aging Your Entire Body Podcast/dr-scott-sherr-stress-light-on-your-skin-are-aging/
2024 Study on endogenous spermidine as essential for rapamycin-induced autophagy and longevity: pubmed.ncbi.nlm.nih.gov/39212197/
Young Goose Companion Booklet: younggoose.com/pages/autophagy-skin-activate-your-bodys-anti-aging-system
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.comInstagram: @young_goose_skincareWed, 27 May 2026 - 31min - 252 - The Overlooked Side of Autophagy Causing Aging - Part 1
What if your skin could literally rebuild itself from the inside out? In this episode, we break down one of the most powerful and misunderstood biological processes in the human body: autophagy.
From its Nobel Prize-winning discovery to the molecular machinery that drives it, we walk you through exactly what autophagy is, how it works at the cellular level, and why it matters far more than most people realize for skin aging.
We explore the two master switches that control autophagy, mTOR and AMPK, and how the constant tug of war between them determines whether your cells are in build mode or cleanup mode. We also explain why most people in the modern world are stuck in permanent mTOR activation, and what that means for how their skin ages over time.
This is Part 1 of our deep dive. In Part 2, we go skin-specific and break down exactly how autophagy renews your skin at the tissue level.
What's Discussed:
(0:19) The "phoenix process": the cellular mechanism rebuilding your skin from the inside out
(3:14) What autophagy actually means, and why the science world ignored it for 30 years
(4:47) How baker's yeast cracked the code that won the 2016 Nobel Prize
(7:14) Inside a single skin cell: the step-by-step breakdown of how autophagy actually works
(10:22) Why autophagy is not destruction, and what this means for your collagen supplements
(16:44) The two master switches controlling whether your cells build or clean
(20:10) The everyday habit silencing your body's most powerful anti-aging system
(26:17) Why aging skin isn't broken, it has just never been told to clean
Resources Mentioned:
Biohacking Beauty Podcast: Ben Azadi: Why 93% of Americans Are Aging Too Fast + What to Do About It: podcasts.apple.com/us/podcast/ben-azadi
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com
Instagram: @young_goose_skincare
Wed, 20 May 2026 - 26min - 251 - Chris Mirabile: Why One Ingredient Will Never Stop You From Aging (And What Actually Does)
Most of what the supplement and skincare industry sells for aging targets one pathway at a time. But your biology does not age that way. It declines across 12 interconnected processes simultaneously, and by the time one of them shows up on your skin, the others have already been running for years.
We at Young Goose believe that skin longevity is not a topical problem. It is a whole biology problem, and the ingredients you choose, how they interact, and whether anyone has actually tested them together matters more than any single molecule ever could.
In this episode, we are joined for the second time around by Chris Mirabile, founder of NOVOS which is the first biotech company to target all 12 biological causes of aging. Chris collaborates with leading researchers at Harvard and MIT and has built his work around one premise: that real interventions require real testing on real humans, not just promising ingredients.
Let's dive in.
What's Discussed:
(2:14) Why single ingredient marketing is a commercial story, not a scientific one.(9:56) The three hallmarks hitting skin hardest and how they feed each other.(12:02) How UV damage depletes 90% of NAD in the skin from a single exposure event.(22:14) Why stacking molecules requires human testing, not just ingredient research.(33:48) The NOVOS cardiovascular study and results that surprised the researchers.(48:12) Why spending more on your biology does not make your protocol safe.(1:02:18) What omics testing reveals that epigenetics alone cannot tell you.(1:09:45) Where skin longevity is heading in the next five years.Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.comInstagram: @young_goose_skincareFind more from Chris Mirabile & Slow My Age:
Instagram: @slowmyage
YouTube: @slowmyage
TikTok:@slowmyage
X: @slowmyage
Personal Blog: slowmyage.com
Find more from NOVOS:
Website: NOVOSlabs.com
Instagram: @NOVOSlabs
Facebook: NOVOS
Youtube: @NOVOSlabs
TikTok: @NOVOSlabs_
X: @NOVOSLabs
Wed, 13 May 2026 - 51min - 250 - Biohackers React To Viral SkinTok Videos on Dermaroller, Red Light Therapy Wands & Tretinoin
Most of what goes viral on SkinTok is missing one thing. The part where someone actually checks if it works.
In this bonus episode, Amitay and Anastasia break down three of the most viral skincare trends circulating today, red light therapy wands, at-home dermarolling, and tretinoin, and run each one through a biohacker's lens. Not to dismiss them outright. But to ask the questions the original videos never do.
What is actually happening at the cellular level? What are the real risks? And where does the marketing stop and the science start?
What’s Discussed:
(2:03) Why red light therapy wands are closer to a flashlight than a treatment.(4:26) What photon accumulation actually means and why moving a wand around your face defeats the purpose.(10:42) Why "sold out" is a marketing claim, not proof that something works.(14:00) What dermarolling actually does to the skin and where the real risks are.(15:21) Why elastin claims in skincare are almost always wrong.(17:06) The difference between at-home dermarolling and professional microneedling.(19:51) How to use a dermaroller safely if you choose to.(28:32) Why tretinoin makes skin worse before it gets better and what that actually means.(32:58) The half-life of vitamin A and why twice a week use barely moves the needle.(34:06) How retinoids accelerate cellular turnover but also drive senescence.(35:44) What can counteract the long-term tradeoffs of tretinoin use.Check out our Mother’s Day Special:
Explore the Mother’s Day gift sets at younggoose.com/pages/mothers-day
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.comInstagram: @young_goose_skincareWed, 06 May 2026 - 33min - 249 - Real Talk on Motherhood, Postpartum Skin, and Rebuilding from the Inside Out with Anastasia Khodzhaeva
Mothers sacrifice so much of themselves to carry another human being in their body for nine months. Even after childbirth, there's a phase called the fourth trimester because babies are still heavily dependent on moms for their survival.
Motherhood looks different for every woman. For Anastasia, who is a first-time mom, motherhood looked particularly different since her family is overseas and she's also running Young Goose with Amitay. Yet, there's something unique when a biohacker becomes a mom that new moms can learn from.
In this Young Goose Mother's Day Special, we celebrate every mother who gives selflessly to their family. We also take a peek into Anastasia's life as a new mom, what changed in her body and mindset, and how she maintained her self-care while taking care of the family and the business.
This episode will make you realize that it takes a village to raise a kid, but it takes a great mom to raise a kid and still come back to herself. Because the only way she can show up fully for others is when she can show up for herself first.
What's Discussed:
(3:11) Who Anastasia was before motherhood: the risk-taker who crossed the world.(6:03) Why Anastasia loves a small circle and how she protects it.(10:09) Why Anastasia went back to work early, and the regret she wants other new moms to avoid.(12:00) Why motherhood is the hardest thing she has ever done, more than building a company.(15:49) How motherhood flipped the dynamic: why the assertive co-CEO becomes the soft parent.(25:26) Postpartum breakouts, cortisol, and why her skin told the story before anything else did.(29:25) What her early postpartum self-care actually looked like.(30:33) The non-negotiables: PEMF mat, lymphatic drainage suit, and red light therapy.(34:04) Anastasia's postpartum bounce-back stack: spermidine, NAD+, and PC.(1:58) How a biohacker reconnects with a body that no longer feels like her own.(4:05) The self-massage course that changed everything.(5:42) What self-care actually looks like in this season of motherhood.(10:02) Redefining energy as a mother: capacity, limits, and the cost of burnout.(16:01) Mindfulness as a skincare tool: why lowering cortisol shows up on your face.(26:06) The 20-minute practice that can stand in for hours of lost sleep.(27:45) The 4-7-8 breathing technique for moms who do not have 20 minutes.(43:28) Advice for new moms who feel self-care is unrealistic in this season.(43:45) The reframe that changes what self-care means for a new mom forever.Check out our Mother’s Day Special:
Explore the Mother’s Day gift sets at https://www.younggoose.com/pages/mothers-day
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at https://younggoose.comInstagram: @young_goose_skincareWed, 29 Apr 2026 - 1h 01min - 248 - Why Niacinamide Is Not the NAD+ Hero You Think It Is
Most of the NAD+ skincare on shelves right now is built on a misunderstanding. And if you've been trusting niacinamide to do the heavy lifting, this episode is going to change how you read a label.
This episode is Part 2 of our NAD+ deep dive. Here, we get into what actually works to raise NAD+ in the skin, the real precursors, the delivery technology that gets them where they need to go, and the mitochondrial support system most brands leave out. We also walk through the lifestyle levers that move the needle, and why one of them becomes non-negotiable for women after a certain age.
If Part 1 explains what steals your NAD+, this episode is where the science gets practical and eye-opening.
What's Discussed:
(5:07) What the clinical data actually says about topical niacinamide(7:21) Why most niacinamide products on your shelf are underdosed(8:16) The roundabout pathway that makes niacinamide a poor NAD+ precursor(9:03) Niacinamide is a brightening agent, not an NAD+ booster(10:15) Why NMN can't cross the skin barrier alone(11:19) CD38 and blocking the enzyme that destroys NAD+(13:03) NAD+ alone is potential energy, not usable energy(13:45) Liposomal encapsulation and how real precursors get into the skin(17:02) The five mitochondrial pathways your skin actually needs(18:53) Senescent cells and the next telomeres conversation(25:17) Why NAD Apex targets NAD+ in three dimensions(26:39) Lifestyle strategies: fasting and the AMPK pathway(28:47) How to get 30 to 50% more NAD+ from caloric restriction through fasting(30:37) The fun fact behind why 16:8 fasting became the standard(33:02) HIIT and its compounding effect on baseline NAD+(34:51) Sleep is an NAD+ dependent repair session, not just rest(39:15) Your skin does 8x more renewal at night(41:38) Sun protection as an NAD+ strategy(44:49) Why you should expose your back more than your face(45:29) Contrast therapy, heat shock proteins, and cold-driven biogenesis(50:32) Why stacking NAD+ boosting activities at 50% beats maxing out one modality(52:49) The perimenopause problem no one is talking about(56:29) Why niacinamide creates homework for the body(1:01:46) You recycle more NAD+ daily than you can ever supplement(1:02:19) 5-Amino-1MQ, the peptide that recycles NAD+(1:05:35) Mitophagy, autophagy, and the role of spermidine(1:06:44) Ergothioneine, the only antioxidant with a direct mitochondrial transporter(1:07:46) Fermented resveratrol and activating SIRT1Check out resources mentioned:
Part 1 of our NAD+ deep dive: The NAD+ Thief Your Skin Can't Escape: CD38, Zombie Cells, and the Decline
Check out our NAD+ Guide: NAD+ & SKIN AGING -The Cellular Energy Connection
Sleep is Skincare episode: How Timing Unlocks Your Body’s Best Skincare Repair
Find more from Young Goose:
Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at https://younggoose.comInstagram: @young_goose_skincareVampire Exosomes: Professional Exosome Serum for Regeneration and Post-Treatment Recovery https://younggoose.com/products/vampire-exosomesWed, 22 Apr 2026 - 59min - 247 - Dr. Alan Bauman: Why Biohackers Are Losing Their Hair Faster Than Everyone Else
A lot of us treat hair loss the way skincare treats wrinkles, as a cosmetic problem to cover up. But almost every case of thinning, recession, or shedding has something deeper driving it, and by the time it shows up in the mirror, a significant amount of density is already gone.
We at Young Goose believe that beauty is whole body care, and hair is one of the most metabolically active tissues in the body. It is also one of the first places systemic stress, hormone shifts, nutrient deficiencies, and inflammation show up.
In this episode, Dr. Alan Bauman joins us to break down the biology of hair aging and the protocols that actually move the needle. Dr. Bauman is the founder of Bauman Medical in Boca Raton and one of the pioneers of modern hair restoration, with nearly three decades of clinical practice and more than 35,000 patients treated.
His core message is simple and urgent: time equals follicles. Every week of delay is density you do not get back. And most people have no idea it is happening until the loss is already visible.
We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover the hidden hair loss risks of GLP-1s and testosterone optimization, the precision diagnostics replacing guesswork, and the red light therapy details almost no one talks about.
Let's dive in!
What's Discussed:
(2:20) How Dr. Bauman became a hair restoration pioneer and the patient who changed everything.(9:50) Why hair is an emotional organ and a biomarker for systemic health.(12:14) Time equals follicles: why every week of delay costs you density.(13:38) The mechanism of androgenetic alopecia and how DHT miniaturizes the follicle.(16:30) Why DHT is not the only driver: stress, inflammation, nutrient deficiency, and GLP-1s.(18:55) The hidden hair loss risks of weight loss peptides and caloric deficits.(21:06) Precision diagnostics: AI-powered microscopy, DNA testing, and preservation first.(23:36) What genetic testing actually tells us about your DHT metabolism pathways.(29:40) Minoxidil and finasteride explained, and why oral microdose is the modern approach.(32:20) Dutasteride, topical finasteride, and when to escalate.(39:41) Copper tripeptide, zinc thymulin, and the peptides with real hair growth data.(42:18) The hair loss side effect of TRT and hormone optimization nobody warns you about.(48:09) Red light therapy for hair: the science, the studies, and what actually works.(52:00) Wavelength precision, power density, and why most devices will not move a follicle.(59:06) Why movement destroys the premise of photobiomodulation.(1:04:36) PRP and modern dual spin protocols for hair regeneration.(1:08:28) Autologous hair follicle stem cell banking and the future of restoration.Find more from Young Goose:
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareVampire Exosomes: Professional Exosome Serum for Regeneration and Post-Treatment Recovery https://younggoose.com/products/vampire-exosomesFind more from Dr. Alan Bauman:
Instagram: @dralanbauman
Youtube: @AlanBaumanMD
Facebook: Bauman Medical Group
Shop:https://dralanbauman.com/
Website: https://www.baumanmedical.com/
Wed, 15 Apr 2026 - 1h 17min - 246 - The NAD+ Thief Your Skin Can't Escape: CD38, Zombie Cells, and the Decline
Most people know NAD+ as a supplement trend. But very few understand what's actually happening inside their skin cells when it runs out or what's stealing it in the first place.
By the time you're 45, you've lost half of the molecule that powers virtually every function keeping your skin young. Sadly, it only gets worse from there.
The enzyme your skin uses for DNA repair can wipe out up to 90% of what's left after a single afternoon in the sun. This isn't a slow, graceful decline. It's a collapse happening beneath the surface long before the wrinkles appear.
In this episode, we will nerd out and break down exactly why NAD+ disappears, who the thieves are, and what the science actually says about getting it back. From the sirtuin-PARP-CD38 trifecta to the zombie cell feedback loop that accelerates the drain with age, this is the most complete picture of NAD+ and skin aging we've put together to date.
We also cover the real differences between NMN, NR, and niacin, why the precursor you choose actually matters, and what to stack with it to protect your methylation pathways.
Ready to nerd out in this with us?
Let's dive in!
What's Discussed:
(4:00) The number that changes how you think about skin aging.(6:03) What NAD+ actually does and why "rechargeable battery" undersells it.(8:18) The three enzyme families consuming your NAD+ as a substrate.(8:23) Sirtuins: the police of your cells and what they cost you.(9:42) PARPs: the fire brigade and why one sunburn nearly wipes you out.(11:16) CD38: the NAD+ Pac-Man that gets worse with age.(15:10) The five-fold decline: what the 2012 tissue study actually found.(16:15) CD38 and the zombie cell feedback loop driving the decline.(19:39) What the depletion actually looks like in the mirror.(28:04) Why NAD+ decline is reversible & supplementation deep dive.(28:41) NMN: how it works and what the studies actually show.(31:50) NR: the most clinically studied precursor and who it's best for.(33:27) Niacin: the $5 option and why most people can't tolerate it.(38:14) Why timing your NAD+ to your circadian rhythm matters.(38:35) TMG and methylation: what to stack and the two-to-one ratio.Learn more about NAD from our previous podcasts and videos:
Previous NAD YouTube Videos:
NAD+, Skincare Science + The Future of Skincare: https://www.youtube.com/watch?v=ZmwYLywwcsA Biohack Your Way to Better Skin - Benefits of NAD Boosting Supplementation for Skincare & Anti-Aging: https://www.youtube.com/watch?v=KIz5MvW7X1M Why Your NAD+ Supplement Isn't Helping Your Skin | The Truth: https://www.youtube.com/watch?v=euIj0eLt4Aw The Science Behind NAD+, Link Between NAD+ Skin Aging, Importance of Precursors: https://www.youtube.com/watch?v=wmsUeQklYY0 The NAD+ Protocol That Could Reverse Skin Aging (Doctors Won't Tell You) | Dr. Scott Sherr: https://www.youtube.com/watch?v=iYJgVSoj_XMPrevious NAD Podcasts:
NAD 101: Unlocking The Secrets To Youthful Skin: https://podcasts.apple.com/us/podcast/nad-101-unlocking-the-secrets-to-youthful-skin/id1552026927?i=1000652231123 The Relationship Between NAD+ and Your Skin, NAD+ Depletion, Bioavailability, Precursors, Sirtuins, and More: https://podcasts.apple.com/us/podcast/22-the-relationship-between-nad-and-your-skin/id1552026927?i=1000568088462 The Science Behind NAD+, the Link Between NAD+ and Skin Aging, and the Importance of Precursors: https://podcasts.apple.com/us/podcast/the-science-behind-nad-the-link-between-nad-and/id1552026927?i=1000615122098 Ben Azadi: How NAD+ Helps Reverse Aging + Skin Problems Connected to Deeper Health Issues: https://podcasts.apple.com/us/podcast/ben-azadi-how-nad-helps-reverse-aging-skin-problems/id1552026927?i=1000662495945 Turn Back the Clock: NAD and Skin Biohacking: https://podcasts.apple.com/us/podcast/turn-back-the-clock-nad-and-skin-biohacking/id1552026927?i=1000681105344Research Studies Mentioned:
Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042357 CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30225-7 Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages: https://www.nature.com/articles/s42255-020-00305-3 Enhanced SIRT1 Activity Mitigates UVB-Induced Senescence in Dermal Fibroblasts: https://pubmed.ncbi.nlm.nih.gov/39401943/ Slc12a8 is a nicotinamide mononucleotide transporter: https://www.nature.com/articles/s42255-018-0009-4 The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: https://link.springer.com/article/10.1007/s11357-022-00705-1 Nicotinamide riboside and nicotinamide mononucleotide facilitate NAD+ synthesis via enterohepatic circulation: https://www.science.org/doi/10.1126/sciadv.adl5154Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults: https://www.nature.com/articles/s41467-018-03421-7Find more from Young Goose:
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareHead to younggoose.com/products/youth-body-cream for 20% offBody Cream: Head to younggoose.com/products/youth-body-cream for 20% offWed, 08 Apr 2026 - 32min - 245 - Dani Conway: The Gut-Liver Detox Connection & How Gut Issues Show Up As Skin Issues
Most people treat their skin like a surface problem. But almost every persistent skin issue, from rosacea to eczema to accelerated aging, has something deeper driving it.
That deeper driver is almost always the gut, the liver, or a backed-up detox pathway. We at Young Goose, always believe that skincare is whole body care and we want our community to identify the deeper causes of skin issues that products alone can’t fix.
In this episode, functional nutrition practitioner Dani Conway joins us to break down why the skin is not the origin of the problem but the exit sign. When the body cannot eliminate toxins efficiently, they take the path of least resistance. For a lot of women, that path is the skin on their faces.
Dani brings nearly 20 years of clinical practice to this conversation, along with a sharp, evidence-grounded perspective on why fixing hormones first is often the wrong starting point and what to address instead.
We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover how to deal with food sensitivities, common misconceptions around hormones and blood sugar testing, and the use of GLP-1 and peptide use.
Let’s dive in!
What's Discussed:
(0:57) How poor detoxification shows up on the skin.
(2:09) The foundational actions to support detox.
(5:44) The lymphatic system explained.
(6:33) Why Dani stopped addressing hormones first.
(8:01) Microplastics, endocrine disruptors, and chemicals women apply to their skin.
(11:40) The gut-skin axis: How gut symptoms always end up on your face.
(13:55) NAD, CD38, and why a bacterial infection in your gut affects cell energy.
(16:59) Why peptides and NAD supplements don't work if the foundation isn't dialed in first.
(21:26) Can you actually fix hormones or just manage them?
(25:12) Real-world food sensitivity examples and how to figure out your personal triggers. (29:41) How to run an elimination diet correctly.
(34:39) The big picture nobody talks about: it's not the food, it's the immune system.
(36:06) The new science on acne: The bacteria and immune system response.
(38:06) Hot take: Why immune optimization is the next mitochondria.
(39:49) CGMs and skin aging: Why Dani actually pulls clients back from data obsession.
(42:09) Fasting insulin ranges: Why the lab's "normal" range is dangerously wide.
(43:35) The role of GLP-1s and how to use them as a therapy instead of a crutch.
(45:12) Dani's hot take on berberine and leptin resistance.
Find more from Young Goose:
- Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare
Find more from Dani Conway:
- Instagram: @DaniConwayOfficialWebsite:https://nutritionthenaturalway.com/The Wellness Collective:https://nutritionthenaturalway.com/drop-the-weight-shred-the-fat/Weight Loss Accelerator Program:https://go.nutritionthenaturalway.com/wlaFree Complimentary Guide:https://go.nutritionthenaturalway.com/hhh
Wed, 01 Apr 2026 - 57min - 244 - Skin Barrier Protocol: How One Reset Makes Every Other Skincare Step Work
Most people think that the stinging feeling, redness or tightness are always good signs of skin detoxification. Tricky enough, it can look like ‘glass skin’ or skin renewal. However, almost always the temporary tight and bright skin is a skin barrier issue in disguise.
Skin barrier damage is one of the most misread signals in skincare. It looks like purging but it is actually your skin telling you it has been pushed past its limit.
It’s easy to think there’s no damage at all because overexfoliation can temporarily give a satisfying baby skin at the cost of long-term skin wellness.
One of the best ways to distinguish normal skin stimulation versus barrier damage is to understand your skin biology. As Anastasia always says, "We're not chasing a 10-day glow. We're chasing a 10-year outcome."
We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover what real skin barrier repair should feel like, the pillars of skin wellness, and how to listen better to your skin to train it to become more resilient.
Resources mentioned:
Barrier Protocol: https://www.younggoose.com/pages/barrier-protocol
What's Discussed:
(04:20-05:11) Why a weak skin barrier makes every other skincare step stop working
(05:11-06:16) The four signs of barrier damage that looks like progress
(06:16-08:29) What is a skin barrier and what happens when the lipid ratio breaks down
(08:29-10:10) How barrier disruption can disguise as purging
(10:10-13:00) A case study of laser-induced barrier damage and the cycle of over-treatment
(13:00-15:11) The three pillars of skin wellness: performance, resilience, and longevity
(15:11-16:52) What your skin should be able to do before you add any heavy stimulation
(16:52-18:30) The three-step barrier reset protocol
(18:30-20:30) Morning versus nighttime barrier: defense vs. repair
(20:30-25:09) The truth about exfoliation culture and the glass skin trend
(25:09-27:00) How to build an exfoliation schedule that works for your skin type
Find more from Young Goose:
- VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare
Wed, 25 Mar 2026 - 31min - 243 - Sleep Is Skincare: How Timing Unlocks Your Body's Best Skin Repair
Did you know that the most powerful anti-aging protocol isn't about how long you sleep? It's about when. Getting eight hours of sleep for skincare feels like a tough feat to achieve especially when life gets in the way.
By understanding how your skin begins its optimal repair time, it’s still possible to achieve the best skin results without the guilt of not sleeping enough.
In our quest in finding the best skincare ingredient for our products, we discovered that hours of sleep do matter, but best skin results happen by following the skin’s optimal program sequences for deep repair.
We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover how melatonin onset, circadian rhythm, growth hormones, and inflammation play a huge role in giving your skin the environment it needs to do its best work.
What's Discussed:
- (1:54-5:09) Why sleep timing matters more than sleep hours for skin repair(07:01-15:19) The three repair windows your skin depends on every night: melatonin onset, growth hormone pulse, and barrier recovery(05:09-5:55) Why dull skin, slow healing, and crepey eyes are often a timing problem — not a product problem(13:28-17:10) How to build a recovery-first nighttime routine before adding any stimulation(37:47-40:47) The silk vs. cotton pillowcase: Which fabric choice is part of your skincare(43:29-47:36) Supplements that support skin repair at night(17:17-17:30) Red light therapy as the only exception to the no-stacking rule
Resources mentioned:
Sleep protocol: https://www.younggoose.com/pages/sleep-protocol
Episode with Anastasia (BeautyFascia): https://podcasts.apple.com/us/podcast/anastasia-beauty-fascia-facial-fascia-and-massage
Episode on Face Taping with Olga from Natural Face Bible: https://podcasts.apple.com/us/podcast/real-japanese-face-taping-explained-with-olga
Find more from Young Goose:
- The Elastin Action Protocol → Engineered for Skin Navigating Elasticity ChangeThe Winter Skin Protocol → Build for How Skin Actually Behaves in WinterVAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare
Wed, 18 Mar 2026 - 47min - 242 - Alex Tarnava: What Hydrogen Really Does to Your Skin
Molecular hydrogen is often described as a selective antioxidant, but that framing is incomplete. In this episode, we explore hydrogen as a mitochondrial hormetic signal that can influence redox balance, inflammatory regulation, and adaptive stress pathways. The key distinction is that delivery route changes mechanism. Oral, inhaled, and topical hydrogen act differently in the body, with different kinetics, tissue distribution, and biological implications.
We dive deeper into this in the Biohacking Beauty Podcast with Alex Tarnava. We discuss why topical hydrogen is gaining attention for skin outcomes, how gut-mediated signaling may drive systemic effects, and why interpreting evidence requires understanding study design, delivery method, and real-world product variability.
WHAT’S DISCUSSED:
(04:52) Why hydrogen is not a traditional antioxidant and what that actually means biologically
(06:17) How different delivery routes change tissue targeting and systemic signaling
(10:09) Why skin aging and inflammatory conditions behave more like a systems problem than a single pathway
(15:10) How mild oxidative stress can activate endogenous antioxidant production
(16:05) The hidden risk of reductive stress from excessive antioxidant use
(17:59) Why inflammation must be regulated rather than suppressed for long-term tissue repair
(28:52) The gut-driven mechanisms that may influence visible skin outcomes
(29:42) How corporate-owned research and investigator-led studies shape the hydrogen evidence landscape
(37:25) Why exaggerated longevity claims distort innovation and erode trust
(50:49) The growing issue of counterfeit hydrogen products and what it signals about market maturity
Find more from Young Goose:
- The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare
Find more from Alex Tarnava:
Website:https://hydrogenwatertablets.com
Instagram: https://www.instagram.com/alextarnava
Wed, 11 Mar 2026 - 58min - 241 - Dr. Scott Sherr: Why Chronic Stress Disrupts Mitochondria and Accelerates Visible Skin Aging
Chronic stress isn’t just a mental or emotional burden. It creates a biological cascade that disrupts mitochondrial function, accelerates inflammation, and shows up visibly in the skin long before deeper symptoms appear.
We dive deeper into this in the Biohacking Beauty Podcast with Dr. Scott Sherr. We also talk about the sympathetic spiral of doom, why skin reflects mitochondrial decline before other symptoms appear, and why sequencing interventions matter more than intensity.
Dr. Scott Sherr is a board-certified internal medicine physician certified in Health Optimization Medicine (HOMe) and a specialist in Hyperbaric Oxygen Therapy. He is the COO of Troscriptions and focuses clinically on mitochondrial health, stress physiology, and advanced recovery protocols.
What's Discussed:
- (01:52) Why chronic stress is not just mental and directly impacts cellular energy(05:17) How modern life keeps the nervous system stuck in chronic fight or flight(07:25) Cortisol and stress hormones disrupting mitochondria and accelerating skin aging(11:16) Why skin aging is often the first visible sign of mitochondrial decline(24:16) The sympathetic spiral of doom explained through energy loss and stress signaling(27:14) Why stress reduction and mitochondrial support must happen at the same time(46:22) Why aggressive skincare and biohacking fail without mitochondrial resilience(50:35) Hyperbaric oxygen therapy, sequencing, and why timing matters more than intensity
Find more from Young Goose:
- The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare
Find more from Dr. Scott Sherr:
Website: https://troscriptions.com
LinkedIn: @troscriptions
Instagram: @drscottsherr @troscriptions
Facebook: @Troscriptions
Youtube: @troscriptions
Tiktok: @troscriptions
Wed, 04 Mar 2026 - 1h 12min - 240 - Anastasia (Beauty Fascia): Facial Fascia and Massage + Lymphatic Drainage for Younger-Looking Skin
Fascia is one of the most overlooked conversations in skin aging. We spend so much time thinking about collagen, serums, injectables, and trending tools, but very few people are talking about the structural system underneath the skin that influences how we actually age.
If you are dealing with under-eye puffiness, jaw tension, posture changes, facial asymmetry, or feeling like your face looks more tired than it should, this episode explores a deeper layer of the conversation. We dive into fascia, fluid movement, breathing patterns, and why your neck and jaw may be playing a much bigger role in your appearance than you realize.
In this conversation, we break down what fascia really is in simple terms and how it connects to collagen production, lymphatic drainage, nervous system regulation, and facial structure over time.
Anastasia is a board-certified Structural Integration Therapist trained in kinesiology, facial muscle neuro rehabilitation, neurovascular release, myofascial release, traditional Chinese medicine, and acupressure. Over the past five years, she has pursued global mentorships and seminars focused on structural and facial regeneration, bringing together multiple disciplines to support facial health, tissue quality, and overall structural balance.
To watch this episode on Youtube click here: https://youtu.be/KRs4dlmfj8s
What's Discussed:
- (11:41) Why facial massage does not stretch skin and how tissue actually adapts(19:38) Under eye puffiness as a drainage issue, not a skin problem(23:12) Collagen cross linking and why fibroblasts avoid rebuilding on damaged matrix(27:23) Glymphatic dysfunction and how poor brain drainage shows up in the face(51:52) What happens to circulation and lymphatic flow when muscles are paralyzed with Botox(53:52) Why mewing fails without addressing neck tension and structural foundation(01:12:23) Phone posture, forward head position, and structural facial aging(01:14:39) Aging as a structural shift before wrinkles ever appear
Find more from Young Goose:
- The Elastin Action Protocol → Engineered for Skin Navigating Elasticity ChangeThe Winter Skin Protocol → Build for How Skin Actually Behaves in WinterVAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare
Find more from Anastasia (Beauty Fascia):
- Website: https://anastasia.beautyInstagram: @anastasiabeautyfasciaYoutube: @anastasiabeautyfasciaTikTok: @anastasiabeautyfascia
Wed, 25 Feb 2026 - 1h 24min - 239 - Dr. Jila Senemar, MD: How Early Perimenopause and Insulin Resistance Drive Skin Aging
Being told your labs are “normal” and your cycle is still regular does not mean your metabolism and hormones are stable. Early insulin resistance can quietly increase inflammation, drive midsection fat gain, and accelerate skin aging years before menopause is officially diagnosed.
In this Biohacking Beauty episode with Dr. Jila Senemar, we break down why regular periods do not rule out perimenopause, why building muscle is one of the most powerful metabolic tools in midlife, and how early testing like DEXA scans can reveal hidden bone loss long before standard guidelines would ever check.
Dr. Jila Senemar is a board-certified OB/GYN with more than 20 years of clinical experience. She is a menopause specialist certified by The Menopause Society and a longevity physician. Her clinical work focuses on perimenopause, menopause, hormone therapy, and midlife women’s health.
What's Discussed:
(02:57) Insulin resistance as an early midlife driver of inflammation and weight gain(03:35) Why more cardio and restriction can worsen midlife metabolic dysfunction(07:27) Regular periods and no hot flashes still align with early perimenopause(09:44) Night waking and unrefreshing sleep as overlooked perimenopause symptoms(15:01) Strength training as a metabolic and hormonal support tool in midlife(24:40) Using DEXA scans at 40 to detect early bone density loss(26:15) Hormone therapy framed around longevity, not just symptom relief(41:14) Progesterone’s role in sleep, mood stability, and early perimenopause supportFind more from Young Goose:
The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareFind more from Dr. Jila Senemar MD, FACOG, MSCP:
Website: https://www.jilamd.comInstagram: @drjilasenemarWed, 18 Feb 2026 - 51min - 238 - Jess Kane (BodyBio): How Omega Ratios, Low Fat Diets, and Damaged Cell Membranes Trigger Skin Aging
Advanced skincare routines are more popular than ever, yet dryness, laxity, and visible aging still persist. The issue isn’t effort or discipline. It’s that skin aging is being treated as a surface-level problem instead of a cellular and structural one.
We dive deeper into this in the latest Biohacking Beauty Podcast with Jess Kane. We also chat about how cell membrane health shapes visible aging, why omega fats are widely misunderstood, and how most “liposomal” supplements never reach the cell.
Jessica Kane is the Co-Owner and Chief Marketing Officer of BodyBio, a third-generation wellness company specializing in cellular health. She works alongside healthcare practitioners and researchers to translate complex cell membrane and lipid science into practical, evidence-based solutions.
What's Discussed:
(06:17) Why advanced skincare and red light therapy still fail without cellular building blocks(07:37) How low-fat nutrition and missing lipids weaken skin structure over time(09:55) Cell membranes explained as the foundation of skin barrier, tone, and elasticity(10:46) How phospholipids act as the “cement” between skin cells and prevent laxity(13:15) Why the omega-6 to omega-3 ratio matters more than taking fish oil alone(15:57) Why most phosphatidylcholine on the market is not truly liposomal(18:28) How “liposomal” labeling works and why most supplements fail cellular delivery(36:01) Why vitamin C and glutathione don’t impact collagen without proper absorptionFind more from Young Goose:
Find ourElastin Protocolhere:https://younggoose.com/pages/elastin-action-protocol-landingFind our Winter Protocolhere:https://younggoose.com/pages/winter-protocolVAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery: https://younggoose.com/products/vampire-exosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com/?utm_source=podcast&utm_medium=appleInstagram: http://instagram.com/young_goose_skincareFind more from Jess Kane:
Website: https://bodybio.com/Instagram: https://instagram.com/jesskaneInstagram: https://www.instagram.com/bodybio/Tiktok: https://tiktok.com/@jesskanebWed, 11 Feb 2026 - 58min - 237 - Valentine’s Day Special: Our Top Skincare Recommendations for Each Other as Co-Founders + Life Partners
It’s Valentine’s Day, and while we don’t usually shape our work around holidays, this one felt different because we’re not just co-founders of Young Goose, we’re life partners. For us, care has always shown up in daily choices and consistency, the same philosophy behind how we think about skin longevity.
In this special episode, we flip the format and recommend ingredients to each other based on real-time skin needs. We get into methylene blue, NAD support, ectoin, retinol, and repair-focused actives through the lens of cellular energy, inflammation control, repair, and long-term resilience.
If you’re listening on Valentine’s Day, we’re honored you’re spending it with us. And if you’re tuning in any other day, we’re just as glad you’re here. Either way, this conversation is about care that lasts and the small, intentional choices that add up over time.
What's Discussed:
(03:38) Why this Valentine’s episode feels different as co-founders and life partners(06:11) Recommending ingredients based on real-time skin needs, not bias(12:38) Methylene blue, red light synergy, and mitochondrial skin energy(17:04) NAD support as the currency behind repair and long-term resilience(20:49) Ectoin, deep hydration, and protection from blue light and pollution(25:10) Retinol results, limitations, and why peptide alternatives matter(27:36) Sun exposure, oxidative stress, and the missing piece of post-UV DNA repairFind more from Young Goose:
The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareFri, 06 Feb 2026 - 26min - 236 - Marina Moiseyeva: Skin Detoxification, GLP-1s, and What Actually Drives Facial Aging
Skin problems are often the body’s earliest warning sign that detoxification, inflammation control, and nutrient absorption are already compromised. When detox demand rises and recovery systems can’t keep up, skin changes and aging-related signs become more pronounced.
In this episode of the Biohacking Beauty Podcast, we sit down with Marina Moiseyeva to explore why medications and aggressive topicals increase detox load, how sweating and lymphatic movement support skin longevity, and why “Ozempic face” is driven by muscle, bone, and nutrient loss rather than fat alone.
Marina Moiseyeva is a Functional Medicine Practitioner and Board Certified Family Nurse Practitioner with 16 years of clinical experience. She is a Certified Diplomate in Anti-Aging and Regenerative Medicine, a member of the American Academy of Anti-Aging Medicine, and the author of Harmonious Healing Blueprint: Biohacking, Regeneration & Health Resilience.
What's Discussed:
(00:00) Why skin functions as a detox organ(07:03) How topical treatments and medications quietly increase the body’s detox burden(11:34) Sweating, hydration, and lymphatic movement as primary detox pathways(19:32) GLP-1s, nutrient absorption, and the real mechanism behind “Ozempic face”(26:09) Bone density, muscle loss, and why structural facial aging is hard to reverse(54:48) What ages skin faster than sun exposure and why sugar-driven inflammation mattersFind more from Young Goose:
Find ourElastin Protocolhere:https://younggoose.com/pages/elastin-action-protocol-landingFind our Winter Protocolhere:https://younggoose.com/pages/winter-protocolVAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery: https://younggoose.com/products/vampire-exosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at younggoose.comInstagram: @young_goose_skincareFind more from Marina Moiseyeva:
Website: https://liveharmoniouslife.comInstagram: @liveharmoniouslifeBooks' Amazon page links here:
Hardcover:https://a.co/d/asQyFGW Paperback: https://a.co/d/gRQhEWEWed, 04 Feb 2026 - 1h 09min - 235 - Joe Radich (R3 Health): Why Skin Treatments Work Better With Physiological Preparation
Advanced skin treatments often underperform for a reason rarely addressed: regeneration cannot occur in a chronically stressed or under-resourced system. Elevated cortisol, inflammation, and metabolic imbalance weaken collagen signaling and tissue repair before any device, injectable, or modality has a chance to work.
In this episode of the Biohacking Beauty Podcast, we sit down with Joe Radich from R3 Health to unpack why physiological preparation determines treatment outcomes.
We explore how internal factors like stress, hormones, micronutrients, and metabolic health shape skin regeneration, and why modalities like peptides, hyperbaric oxygen, and exosomes only work as well as the system they’re introduced into.
Joe Radich is an NCCPA board-certified Physician Assistant specializing in regenerative medicine and the founder of R3 Health. He trains physicians and mid-level practitioners in stem cells, PRP, exosomes, and biohacking-based clinical protocols, with expertise spanning orthopedic, aesthetic, hair restoration, and regenerative applications.
What's Discussed:
(06:42) Why chronic stress and cortisol are silent drivers of visible skin aging
(10:18) Preparing the body before skin treatments and why physiology determines outcomes
(14:07) Why microneedling success depends on internal biology, not just technique
(18:55) The most common lab patterns behind poor skin regeneration and chronic inflammation
(24:31) Hormonal imbalance vs hormone deficiency and how both affect skin aging
(33:41) GHK-Cu and peptides as signaling tools for connective tissue regeneration
(38:09) Hyperbaric oxygen as a force multiplier for skin repair, recovery, and longevity
(44:06) Exosomes and regenerative biologics and why sourcing and quality determine results
Find more from Young Goose:
VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com Instagram: @young_goose_skincareWinter Skincare Protocol: https://www.younggoose.com/pages/winter-protocolFind more from Joe Radich (R3 Health):
Website: https://josephradich.com, https://r3health.co
Instagram: @joeradich_
Wed, 28 Jan 2026 - 1h 09min - 234 - Collagen vs. Elastin For Skin Aging: Why Collagen Is Over-Credited
Skin sagging, crepiness, and loss of bounce are often blamed on collagen loss, yet the real driver sits elsewhere in the skin’s architecture. Elastin degradation accumulates quietly over time, shaping how skin functions long before changes fully register in the mirror.
In this Biohacking Beauty episode, we unpack why rebuilding elastin is largely a myth, how elastin breakdown differs fundamentally from collagen loss, and how even a single period of stress can influence skin integrity for decades.
We also examine how collagen is over-credited in conversations about sagging and how lasers and radiofrequency treatments can create temporary tightening while promoting long-term fibrotic remodeling that undermines true elasticity. Tune in.
What's Discussed:
(05:58) Why Elastin, Not Collagen, Drives Skin Bounce and Elastic Recovery
(07:54) Elastin’s 70-Year Half-Life and Why Skin Aging Is Mostly About Preservation
(11:39) Why Rebuilding Elastin Is Largely a Myth After Puberty
(21:10) Why Collagen Loss Is Over-Credited in Skin Sagging
(23:12) Lasers, RF and Fibrotic Remodeling vs True Skin Elasticity
(26:50) The Elastin Enemies: UV, Oxidative Stress, Glycation and Inflammation
(31:39) Preservation Over Correction: Building a Daily Elastin-Protective Strategy
(34:01) Signal-Based Remodeling: Supporting Elastic Function Without Chronic Inflammation
Find more from Young Goose:
VAMPIRE EXOSOMES: Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com Instagram: @young_goose_skincareFind our Winter Protocol here: https://www.younggoose.com/pages/winter-protocolFind our Elastin Action Protocol here: https://www.younggoose.com/pages/elastin-action-protocol-landingWed, 21 Jan 2026 - 53min - 233 - Dylan Gemelli: Injectable Peptides, PRP Exosomes and Skin Repair
Most conversations about advanced skin treatments stay at the surface, particularly around regenerative approaches, overlooking why lasting results are so hard to achieve.
We dive deeper into this in the latest Biohacking Beauty episode with Dylan Gemelli. We explore why oral peptides often fall short, and how BPC-157 relates to gut healing, inflammation resolution, and collagen repair. We also unpack the real mechanism behind PRP facials, and how neuromodulating peptides compare to Botox over the long term.
Dylan Gemelli is a prominent figure in the fitness and biohacking space and the host of the Dylan Gemelli Podcast. He is currently completing a master’s degree in dietetics and holds certifications as an integrative health professional and cellular health advisor, with his work centered on educating audiences about peptides, longevity, cellular health, nutrition, and neuroscience.
What's Discussed:
(09:07) The real risks of peptides, lack of regulation, and why quality matters(25:56) BPC-157 beyond athletics: gut healing, inflammation resolution, and collagen repair(29:44) Why injectable peptides outperform oral and one-off aesthetic treatments(32:51) Why consistency and loading phases determine peptide results(37:00) GHK-Cu and why copper peptides matter for skin, hair, and tissue repair(46:32) Neuromodulating peptides vs Botox and long-term wrinkle prevention(51:21) PRP facials work because of exosomes, not needlesFind more from Young Goose:
VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com Instagram: @young_goose_skincareFind out everything you need to know about our Winter Protocol here: https://www.younggoose.com/pages/winter-protocolFind more from Dylan Gemelli:
Website: www.dylangemelli.com
Instagram: @dylangemelli
Wed, 14 Jan 2026 - 1h 07min - 232 - How Winter Accelerates Skin Aging and the Best Protocols to Reverse It
Ever wonder why your skin changes so much in winter?
In this episode of Biohacking Beauty, we explain what actually happens when humidity drops, TEWL rises and indoor heating pulls moisture from the skin. We also talk about UVA exposure in cold months, lifestyle shifts that increase oxidative stress and why winter puts more pressure on your skin’s repair systems.
We break down the winter ingredients that matter most, like ceramides, barrier lipids, vitamin F, beta glucan, hyaluronic acid, peptides, NAD precursors and exosomes, and how to use them in a routine that supports barrier strength and cellular energy. We also share simple protocol adjustments for different climates and biological skin ages.
If you want a clear strategy for keeping your skin healthy and supported through the colder months, this episode gives you everything you need.
What's Discussed:
(00:36) How Winter Alters Skin Biology and Accelerates Aging
(03:01) TEWL and Barrier Breakdown: Why Skin Gets Drier and More Reactive
(06:26) The Hidden Winter Risk: UVA, Snow Reflection and Daily SPF Needs
(12:47) Glycation, Inflammaging and NAD Decline During Winter
(15:18) Essential Winter Ingredients: Ceramides, Lipids, Vitamin F and Smart Hydration
(21:43) Longevity Actives: NAD Precursors, Peptides, Exosomes and Mitochondrial Support
(28:11) Building the Winter Routine: Climate Adjustments and Repair Protocols
(37:41) Tiered Protocols for Every Age: 30s, 40s, 50s and Beyond
Links Mentioned in This Episode:
Watch our Instagram Reel on Red Light Therapy here!
You can find Young Goose's Winter Protocol here!
Find more from Young Goose:
- VAMPIRE EXOSOMES: Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com Instagram: @young_goose_skincare
Wed, 07 Jan 2026 - 1h 08min - 231 - Eva Hooft: How Emotions and Trauma Cause Aging Skin
What if fine lines, breakouts, and flare-ups are not just skin issues, but the body replaying old experiences it never got to resolve? In this episode, we explore how nervous system patterns, unresolved emotion, and the way we hold stress in the body can quietly shape how our skin ages over time. We look at the skin as a boundary, a canvas, and a reflection of how safe we feel in the world.
We talk with practitioner Eva Hooft about psychosomatics, face mapping, and the cell danger response, and how a chronically dysregulated system keeps inflammation and premature aging on a loop. Eva explains how somatic work can shift bowel function, circulation, and visible radiance, and why she often sees the liver and drainage as the missing link in chronic skin problems. We also dig into mineral balance, heavy metals, community, and why sustainable protocols have to respect both physiology and emotion.
Eva Hooft is a somatic and detox practitioner who combines nervous system work, subconscious reprogramming, and mineral-based detox to help clients unwind chronic symptoms from the inside out. Through group programs, one-to-one work, and education, she guides people to build safety in the body, restore drainage, and release stored burdens so their health and skin can reflect a more regulated state.
We Also Discuss:
(00:54) How Unresolved Emotion Shows Up on the Skin
(08:23) The Cell Danger Response and Chronic Inflammation
(13:25) Somatic Practices That Shift Physical Health
(19:41) Liver Congestion, Bowel Health, and Clear Skin
(24:28) Mineral Balance, Heavy Metals, and Nervous System Stress
(30:27) Community, Safety, and the Biology of Healing
(34:27) Blending Subconscious Work with Detox Protocols
(38:19) Botox, Natural Alternatives, and Sustainable Beauty
Find more from Young Goose:
Vampire Exosomes→ Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFind more from Eva Hooft:
Instagram: @eva.hooft
Website: evahooft.com
Wed, 31 Dec 2025 - 58min - 230 - Liz Kennedy: Magnetic Beauty, Where Consciousness Meets Biohacking
Everyone is chasing the next skincare hack, yet true beauty begins far deeper than a product. It grows through awareness, alignment, and how we move through life.
In this episode, we sit down with beauty expert and coach Liz Kennedy to explore how biohacking, mindset, and consciousness work together to create what she calls magnetic beauty. We discuss how affirmations, community, and daily rituals strengthen your energy, as well as how outer practices such as peptides, NAD, and red light therapy enhance results when your inner world is balanced.
Liz explains her approach to conscious biohacking and shares why practices like grounding, movement, and SPF are essential for long-term radiance. She also reveals how to integrate micro habits, her “pockets of peace” into modern routines while staying consistent, realistic, and connected.
Liz Kennedy is a celebrity beauty expert, coach, and speaker who merges skincare science with consciousness and community. Through her events, workshops, and social media, she helps women cultivate beauty that reflects vitality, confidence, and purpose.
We Also Discuss:
(00:54) The Real Meaning of Magnetic Beauty and Conscious Biohacking
(03:14) How Energy, Mindset, and Confidence Shape Physical Beauty
(08:00) Daily Habits That Boost Radiance: Movement, SPF, and Grounding
(12:20) Why Community and Female Connection Regulate Stress and Longevity
(20:39) Aging with Power: Reframing How We See Time and Self-Love
(31:14) Integrating Affirmations and Skincare for Emotional Resilience
(34:13) The Truth About Peptides, NAD, and At-Home Biohacking
(44:29) Cold Plunge Controversy: Why Some Methods May Disrupt Female Balance
Find more from Young Goose:
Blue Peptide Spray:Cellular hydration meets antioxidant power Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFind more from Liz Kennedy:
Instagram: @ Liz Kennedy
TikTok: lizkennedy__
Facebook: Liz Kennedy
Wed, 24 Dec 2025 - 55min - 229 - Exosomes 101: The Truth About Cellular Messaging in Skincare - Part 2
Many listeners asked us to go deeper into exosomes, and this episode expands on everything that most brands avoid talking about: count, consistency, purity, and microRNA composition. We explain why exosomes on a label don’t mean much without verified numbers, and how dose shapes whether the skin actually receives a biologically meaningful message.
We walk through why platelet-derived exosomes offer the clearest communication to human skin, why microRNAs matter more than growth factors alone, and how publishing full sequencing data creates a new standard for transparency in longevity skincare. We also explore the synergy between exosomes and NAD+, how cellular energy drives repair, and why combining messenger and fuel creates a regenerative loop the skin can sustain.
This episode gives listeners a clear, science-driven understanding of how exosome formulas should be evaluated and what truly defines high-performance regenerative skincare.
As founders of Young Goose Skincare, we focus on bringing advanced longevity science into daily routines through transparency, validated potency, and clinically guided innovation.
We Also Discuss:
(00:19) Why “Exosomes on the Label” Tells You Almost Nothing
(01:48) The Dose Problem: How Most Exosome Serums Miss Biological Activity
(03:11) Why microRNA is the Real Engine Behind Skin Repair
(05:16) The Transparency Gap in Skincare, and How We’re Closing It
(09:21) Exosomes as Messages, NAD+ as the Battery
(12:21) Clearing Senescent Cells and Restoring Youthful Function
Find more from Young Goose:
VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery →Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareWed, 17 Dec 2025 - 21min - 228 - Exosomes 101: The Truth About Cellular Messaging in Skincare - Part 1
Many listeners have been curious about exosomes, and this episode offers a simple, science-based foundation for understanding them. We explore what exosomes are, how they act as communication packets between cells, and why they play such an important role in skin rejuvenation.
We walk through the three main categories of exosomes found in skincare, plant, stem cell, and platelet-derived, and discuss how each behaves differently inside the skin. We explain what happens when cellular signals weaken with age, what we’ve learned through PRP and regenerative medicine, and why not every exosome speaks the same biological language. We also touch on dose, purity, and consistency, which shape how effective an exosome formula can be.
This episode gives listeners a clear, approachable starting point for navigating this rapidly growing area of skincare and understanding what truly supports long-term repair.
As founders of Young Goose Skincare, we focus on bringing advanced regenerative science into everyday skincare through education and clinically guided innovation.
We Also Discuss:
(00:00) Integrating Dermatology, Health Optimization, and Longevity Medicine
(04:38) How Skin Both Reflects and Influences Systemic Health
(08:39) The Connection Between Stress, Cortisol, and Skin Function
(10:17) Clarifying Sunscreen Science, Hormonal Changes, and Menopause
(13:51) Defining True Prejuvenation and the Role of Softwave Technology
(19:40) Exploring RLX201 (ReQ) and Innovations in Skin Longevity
(32:20) Linking Inflammation, Oxidative Stress, and Visible Aging
(37:56) Applying Critical Thinking to the Future of Longevity Medicine
(46:18) Rethinking Fillers, Structural Balance, and Subtle Aesthetic Enhancement
(58:42) Building Longevity Habits for Lifelong Skin Health
Find more from Young Goose:
VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareWed, 10 Dec 2025 - 22min - 227 - Real Japanese Face Taping Explained with Olga from Natural Face Bible
We have seen face taping explode across social media, yet very few people understand what real Japanese face taping actually does for the skin. Most viral videos show shortcuts or stickers that never interact with fascia, muscle tension, or lymphatic flow. In this episode, we explore the method behind true face taping and why the right tape, placement, and technique can support healthier aging at a biological level.
In this episode of Biohacking Beauty, we sit down withOlga fromNatural Face Bible to unpack how Japanese medical grade tape lifts the upper tissue layers, boosts blood flow, reduces stagnation, and encourages lymphatic drainage. Olga explains how this simple practice can soften dynamic wrinkles, support TMJ tension, and optimize circulation overnight. She also shares why technique matters, how anatomy guides proper placement, and why face taping pairs so well with facial massage, gua sha, and high quality skincare.
We also dive into common mistakes, what to avoid for skin barrier safety, how to integrate face taping with or without injectables, and the reason this tool works best as part of a long term routine rather than a quick hack. This conversation gives clarity to a trend that has been misunderstood and reveals how consistent, correct taping can become a powerful addition to any longevity focused skincare approach.
We Also Discuss:
(00:00) Why Japanese Face Taping Works When Stickers Do Not
(03:42) How Tape Lifts Fascia, Improves Flow, and Reduces Stagnation
(07:15) Dynamic Wrinkles, Muscle Tension, and TMJ Support
(11:28) Choosing the Correct Japanese Medical Grade Tape
(15:04) Safe Application for Sensitive, Acne Prone, or Reactive Skin
(19:10) How Taping Interacts with Facial Massage and Gua Sha
(24:36) What to Avoid After Botox, Peels, or Microneedling
(29:58) Techniques That Protect the Skin Barrier Long Term
(33:21) Turning Face Taping into a Consistent Longevity Habit
Find more from Young Goose:
VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFind more from Olga, Natural Face Bible:
Website: thenaturalfaces.com
Tik Tok: @naturalfacebible
Instagram: naturalfacebible
You Tube: @naturalfacebible
Wed, 03 Dec 2025 - 1h 08min - 226 - Dr. Doris Day: Reverse Skin Aging By Fixing Inflammation
We’ve always said that healthy skin starts from within, but few people understand how deeply skin and longevity are connected. Every wrinkle, blemish, or loss of elasticity begins with inflammation and cellular stress that ripple throughout the body.
In this episode, we sit down with world-renowned dermatologist Dr. Doris Day to explore how the skin doesn’t just reflect your health, it drives it. From managing inflammation to restoring collagen through sleep, nutrition, and resistance training, Dr. Day reveals why true skin longevity starts at the cellular level.
We also discuss the rise of prejuvenation, the science behind Softwave and exosomes, and how new molecules like RLX201 (ReQ) are changing the way we approach aging. Dr. Day shares how to rethink fillers, balance hormones, and build skin health that lasts decades, not months.
We Also Discuss:
(00:00) Blending Dermatology, Health Optimization, and Longevity
(04:38) How Skin Reflects and Affects Whole-Body Health
(08:39) Stress, Cortisol, and the Skin-Brain Connection
(10:17) The Truth About Sunscreen, Hormones, and Menopause
(13:51) Real Prejuvenation and the Rise of Softwave
(19:40) RLX201 (ReQ) and the Future of Skin Longevity
(32:20) Inflammation, Oxidative Stress, and Aging Skin
(37:56) Critical Thinking and the Future of Longevity Medicine
(46:18) Fillers, Balance, and the Art of Subtle Enhancement
(58:42) Longevity Habits for Better Skin and Health
Find more from Young Goose:
Blue Peptide Spray:Cellular hydration meets antioxidant power →Blue Peptide SprayUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFind more from Dr. Doris Day
Website: https://dorisdaymd.com
Instagram: @drdorisday
LinkedIn: Doris Day, MD
Wed, 26 Nov 2025 - 1h 05min - 225 - Fady & Marina: How Real-Time Hormone Data Extends Longevity
We’ve always believed that data drives better health, but even we were surprised by how powerful hormone data can be. Hormones influence everything from how we age to how our skin repairs itself, yet most people only test them once a year, if at all.
In this episode, we sit down with Fadyand Marina from Eli Health to explore how real-time hormone testing is changing the way we understand health optimization. Their saliva-based technology tracks cortisol and progesterone with over 90 percent lab-comparable accuracy, while their AI-powered app translates results into actionable lifestyle insights.
We also unpack how cortisol rhythm shapes energy, mood, and skin health, why “cortisol face” is real, and how frequent hormone tracking can help prevent stress-related aging before it appears on the skin. Fady and Marina, founders of Eli Health, are redefining hormone care with a science-driven, ethically designed platform that keeps data and decisions in your hands.
We Also Discuss:
(01:07) How At-Home Hormone Testing Works
(02:28) The Accuracy of Real-Time Cortisol and Progesterone Testing
(04:20) Understanding Your Diurnal Cortisol Curve
(07:13) AI-Powered Lifestyle Recommendations for Stress and Sleep
(10:52) Using Hormone Insights to Personalize Your Routine
(14:52) Cortisol, Skin Health, and “Cortisol Face”
(19:22) The Rise of Frequent Hormone Tracking (“Fitbit for Hormones”)
(24:11) Testosterone and Estradiol: The Next Frontier
(37:38) Timing Skincare Treatments to Your Hormone Cycle
(41:33) Ethics, Privacy, and Data Ownership in Health Tech
(47:52) The Future of Hormone Tracking and Longevity
Find more from Young Goose:
Blue Peptide Spray:Cellular hydration meets antioxidant power →Blue Peptide SprayUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFind more from Eli Health
Website: eli.health
Instagram: @myelihealth
LinkedIn: Eli Health
Wed, 19 Nov 2025 - 55min - 224 - Nathalie Niddam: Peptides, Bioregulators, and the Truth About Skin Longevity
Everyone online is talking about peptides like they’re the next collagen powder, but most people are skipping the most important part: is your body even in a state to heal?
In this episode, we sit down with longevity expert Nat Niddam to get clear on what peptides actually are, how they work in the body, and where people are getting this conversation dangerously wrong. We talk about the difference between signaling peptides and bioregulator peptides, why inflammation and gut integrity determine whether you’ll see real results, and why “anti-aging for skin” is not as simple as injecting the trendy thing from Instagram.
We also dig into BPC-157, TB-500, growth hormone secretagogues, and the pineal, thymus, and vascular bioregulators, including when they can accelerate repair, and when they’re a terrible idea. Nat explains why your skin is a mirror of internal stress, mitochondrial function, and recovery, and why trying to force aesthetic results on top of chronic inflammation is like trying to build a house that’s already on fire.
Nat Niddam is a certified nutritionist, longevity practitioner, and one of the most trusted voices in the peptide and bioregulator space. She helps clients approach repair, recovery, and aging with strategy instead of guesswork.
We Also Discuss:
(00:01) What Peptides Really Are, and Why Everyone’s Talking About Them
(08:45) Inflammation: The Silent Blocker That Stops Peptides from Working
(18:58) The Longevity Stack: Bioregulators, Immunity, and Cellular Repair
(29:39) Beginner Protocols: How to Start Peptide Therapy Safely
(37:31) From Gut to Glow: Peptides, Healing, and Immune Support
(51:18) The Growth Hormone Question, Repair, Recovery, and Real Risks
Find more from Young Goose:
Blue Peptide Spray:Cellular hydration meets antioxidant power →Blue Peptide SprayUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFind more from Nathalie Niddam:
Instagram: https://www.instagram.com/nathalien iddam
Website: https://www.natniddam.com/
Wed, 12 Nov 2025 - 1h 06min - 223 - Karin Adoni: What Most People Miss About GLP-s, Food, Inflammation, and Skin
What if the secret to better skin isn’t another serum or laser, but lowering inflammation from the inside out?
In this episode, I sit down with Karin Adoni, a certified holistic nutritionist, to talk about how food, sleep, and everyday toxins shape the way we age. Karin shares how she turned her own recovery from eating disorders into a mission to help women rebuild their metabolism and hormone balance naturally.
We break down why ultra-processed foods and seed oils accelerate aging, how gut health drives skin health, and why sustainable change starts with real food, clean water, and better sleep, not shortcuts.
Karin Adoni is a certified holistic nutritionist and founder of Karin Adoni Nutrition. She specializes in helping women heal inflammation, balance hormones, and age well through realistic, empowering nutrition and lifestyle changes.
We Also Discuss:
(00:01) From Eating Disorders to Empowered Nutrition
(07:44) The Real Pillars of Wellness (That Actually Work)
(13:21) How Food and Inflammation Shape Aging
(27:06) The Ugly Truth About “Skinny Shots” and GLP-1s
(34:13) Hormones, Toxins, and the Hidden Drivers of Skin Aging
(44:35) Building a Personalized Nutrition Plan That Lasts
Find more from Young Goose:
Blue Peptide Spray:Cellular hydration meets antioxidant power →Blue Peptide SprayUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFind more from Karin Adoni:
Website: https://karinadoni.com/
Instagram: @karinadoninutrition/
Tiktok: @karinadoninutrition
Wed, 05 Nov 2025 - 48min - 222 - Joel Marshall: Microneedling, Exosomes & Why RF Isn’t Really Microneedling
What if the best way to rejuvenate your skin isn’t lasers, peels, or expensive devices, but teaching your skin to repair itself?
In this episode, Joel Marshall, Founder and CEO of Dp Derm joins us to reveal how modern microneedling has evolved from rollers and stamps into the precision of the Dermapen 4. We explain how controlled micro-injuries stimulate natural collagen production, break down scar tissue, and restore youthful function without the risks of heat-based treatments. He also shares why so-called radiofrequency microneedling is misleading and potentially harmful.
We also explore the role of exosomes, NAD⁺, vitamin C, and licorice root extract in amplifying results, along with why pre-treatment preparation and post-care are essential for long-term outcomes. Joel’s mission is clear: make skin health accessible and effective through science-driven protocols, not marketing gimmicks.
Joel Marshall is the Founder and CEO of Dp Derm, the US home of DermapenWorld, and a global leader in professional microneedling technology. He has pioneered safer, smarter, and more effective approaches to skin rejuvenation.
We Also Discuss:
(00:01) Microneedling Uncovered: Why Tiny Injuries Transform Skin
(06:59) Lasers vs. Needles: Why Heat Isn’t Always Better
(12:10) The RF Controversy: Why It’s Not True Microneedling
(18:45) Inside the Industry: The Hidden Challenges of Microneedling
(25:00) Exosomes Explained: The Future of Skin Regeneration
(35:45) Supercharging Skincare: Can Microneedling Really Boost Absorption?
(45:38) Red Light, Cold Plunge, and Microneedling—What Actually Works?
(48:41) Truth or Hype: The Biggest Microneedling Myths Explained
Find more from Young Goose:
Blue Peptide Spray – Cellular hydration meets antioxidant power →Blue Peptide SprayAmplifying Essence – Prime skin for deeper absorption →Amplifying essenceThe YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for →Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/Instagram:@young_goose_skincareFind more from Joel Marshall:
Website: https://dpderm.com/
Instagram: @joel_dpderm
Instagram: @dpderm
Wed, 29 Oct 2025 - 56min - 221 - GHK-Cu Explained: The Copper Peptide That Signals Collagen Repair
Most people hear “copper peptide” and think “trend”. But GHK-Cu isn’t new, it’s a naturally occurring bioregulator your body already uses to repair, rebuild, and rejuvenate skin.
In this episode of Biohacking Beauty, we break down why GHK-Cu deserves its cult status in longevity skincare. We also unpack how this tripeptide binds copper to signal fibroblasts, activate collagen and elastin genes, and restore damaged tissue at the cellular level. You’ll learn why 3% is the sweet spot for results without irritation, how GHK-Cu works synergistically with retinol, vitamin C, methylene blue, and NAD+, and what makes pharmaceutical-grade sourcing critical for performance.
If you’ve ever wondered whether GHK-Cu can truly “reset” aging cells or how it compares to retinol, this episode connects the dots between biochemistry and visible results, showing how small, precise molecules can drive profound, measurable change in your skin’s longevity.
What's Discussed:
(00:00) What makes ghk-cu more than a “trendy copper peptide”
(02:20) How fibroblasts, collagen genes, and epigenetics work together
(07:19) Why 3% ghk-cu is the sweet spot for results without irritation
(10:22) Retinol, vitamin c, and ghk-cu, the synergy your skin actually needs
(18:24) Methylene blue, nad+, and the ultimate skin longevity stack
Find more from Young Goose:
Blue Peptide Spray – Cellular hydration meets antioxidant power → Blue Peptide SprayThe YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFri, 24 Oct 2025 - 21min - 220 - Can Vampire Exosomes Really Rebuild Aging Skin? Here’s the Science
Exosomes aren’t just a buzzword, they’re nanoscale messengers that deliver the body’s own repair instructions. In this episode of Biohacking Beauty, we unpack the science of platelet-derived, or “vampire,” exosomes and how they go beyond conventional growth factors to target aging at its root.
You’ll learn how microRNA inside platelet exosomes can reduce senescence signals, trigger collagen and elastin renewal, and activate autophagy for deeper cellular repair. The hosts also explore how formulation stability, ingredient compatibility, and third-party quantification make or break an exosome product.
If you’ve ever wondered how PRP exosomes compare to traditional PRP facials, or why pairing them with NAD-boosting actives can amplify skin longevity, this episode explains the real mechanisms behind the hype, helping you understand what it takes for skin to truly act younger, not just look it.
What's Discussed:
(00:00) Redefining Skin Longevity Through Cellular Repair
(06:07) How Exosomes Became the Next Frontier in Regenerative Skincare
(16:00) Why Platelet-Derived Exosomes Deliver the Most Potent Repair Signals
(23:54) The Real Anti-Aging Data Behind PRP Exosomes
(32:35) Exosomes vs. Retinoids, Fillers, and Lasers, What the Evidence Shows
(46:30) Elevating Repair Capacity: Exosomes Meet Rejuve NAD
Find more from Young Goose:
Vampire Exosomes: Experience the world’s highest-potency exosome serum here → Vampire ExosomesUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareWed, 22 Oct 2025 - 56min - 219 - The Skincare Ingredients That Don’t Live Up to the Hype
What if the products you’re being told to buy are doing more harm than good?
In this episode of Biohacking Beauty, we strip it back to unfiltered opinions, no scripts, no fluff, just real talk about the ingredients and habits that get way too much attention in skincare.
We call out why certain “hero” ingredients, like high-dose niacinamide, may actually backfire with chronic use, and why collagen powders in hot coffee aren’t the miracle they’re sold as. We dig into the over-exfoliation trap, explain why protecting your barrier is the foundation for every other biohack, and spotlight methylene blue as one of the most underutilized longevity tools for skin.
At the end of the day, trends will come and go, but your skin cells don’t follow hype — they respond to biology. This episode will change the way you think about your routine.
What's Discussed:
(00:07) The skincare lies influencers keep repeating
(00:40) Niacinamide: hero ingredient or hidden problem?
(10:28) The next-gen ingredients that actually reprogram skin aging
(22:08) Myths that won’t die: pores, collagen drinks & celebrity skincare lines
(29:23) Why your skin barrier is the foundation of true longevity skincare
Find more from Young Goose:
Blue Peptide Spray – Cellular hydration meets antioxidant power →Blue Peptide SpraySpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for →Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram:@young_goose_skincareWed, 15 Oct 2025 - 37min - 218 - Spirulina: The “Blue-Green” Secret Behind Youthful Skin
Most people know spirulina as a superfood: a bright green powder you toss into smoothies.
But what happens when this blue-green algae becomes a skincare ingredient?
In this episode of Biohacking Beauty, we go behind the science to explain why spirulina deserves a place in your longevity routine.
We break down how its unique peptides, antioxidants, and minerals defend against oxidative stress, boost collagen, and calm inflammation, all while keeping skin hydrated and resilient. We also share how spirulina fights acne, supports barrier repair, and even offers mild UV protection.
You’ll hear how Young Goose sources Spirulina AP, a purified, heavy-metal-free extract with clinical data behind it, and why the way it’s formulated makes all the difference between irritation and true repair.
If you’ve ever wondered whether spirulina works better in your smoothie or on your skin, this short and science-packed episode clears it up.
What's Discussed:
(00:00) Blue Peptide Spray + Why Spirulina Deserves the Spotlight
(03:42) How Spirulina Fights Aging, Inflammation, and Collagen Loss
(07:23) Spirulina for Acne, Hydration, and Brightening
(11:40) The Truth About Using Spirulina Orally vs. Topically
(16:29) Is Spirulina the Next Big Skincare Trend, or an Evergreen Classic?
Find more from Young Goose:
Blue Peptide Spray –Cellular hydration meets antioxidant power →Blue Peptide SprayUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFri, 10 Oct 2025 - 17min - 217 - PRP, Red Light & Skincare Myths That Age You Faster
What if the most popular skin treatments today are quietly accelerating aging beneath the surface?
In this episode of Biohacking Beauty, we go unfiltered, sharing the procedures we actually trust, the ones we avoid, and the rules we’re not afraid to break.
We explain why microneedling with PRP remains the gold standard for regeneration, why red light therapy is the ultimate mitochondria hack, and how pairing it with our Ladder Serum doubles the results. We also reveal why your skin’s metabolic state, NAD+ levels, senescence, and mitochondrial function determine how well any treatment works.
Along the way, we cut through Instagram hype, debunk outdated myths, and reveal what actually holds up to real skin biology. You don’t want to miss this one.
We Also Discuss:
Why Most Skincare Hacks Fail at the Cellular Level
The Hidden Damage Behind “Hot” Procedures
Rules We Break for Better Skin
Face Taping vs. Botox and Other Surprises
The Skincare Habits That Age You Faster
Ingredients That Don’t Deserve the Hype
The Molecules That Could Redefine Skin Longevity
Where Most People Waste Their Skincare Budget
eBook Mentioned in This Episode:The Longevity Skin Protocol: Biohacking Your Way to Age Reversal
Find more from Young Goose:
The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareWed, 08 Oct 2025 - 50min - 216 - Dr. Sarah Daccarett: Hormones, Stress & Why Women Age Faster Than Men
What if stress isn’t the reason your hormones are crashing, what if it’s the other way around? In this episode of Biohacking Beauty, we sit down with longevity clinician Dr. Sarah Daccarett to explore how early hormone decline sets women up for stress intolerance, immune dysfunction, and accelerated aging.
We will explain why telling women to “just de-stress” misses the point, how estrogen and progesterone regulate immune balance, and why autoimmune disease skyrockets when these hormones drop. We also dive into the role of environmental toxins and birth control in shutting down protective signaling, and why most standard hormone therapies fail because of outdated formulations and delivery systems.
You’ll hear why optimizing hormones in your 20s and 30s is critical for skin health, sleep, and vitality, why waiting until menopause is too late, and how Sarah is rethinking women’s health.
Dr. Sarah Daccarett is the founder of InnerBalance, a telehealth platform rethinking women’s hormone optimization with clinically precise dosing, advanced delivery systems, and ongoing clinical support in 46 states.
We Also Discuss:
(00:00) Why Women’s Hormones Decline Early
(15:08) Hormones, Immunity & Skin Aging
(25:32) The Future of Hormone Therapy
(29:38) Why Women Age Faster Than Men
(40:00) Telehealth & Hormone Optimization
(50:00) Diet’s Hidden Impact on Hormones
(01:04:19) Hormones as the Foundation of Longevity
Find more from Young Goose:
The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFind more from Dr. Sarah Daccarett, MD:
Instagram: @sarahdaccarettmd
Instagram: @innerbalancemd
Website: https://www.innerbalance.com/
Wed, 01 Oct 2025 - 1h 06min - 215 - Why We Had to Reinvent the Facial Mist (And Why This One Works)
Why do most facial sprays feel great, but deliver nothing long term?
In this episode of Biohacking Beauty, we reveal the science behind our new Blue Peptide Spray, the first mist with a clinical dose of methylene blue, plus NAD+ precursors, GHK-Cu, and SOD. It’s designed to optimize mitochondrial energy, reduce oxidative stress, and support true skin repair.
We break down why methylene blue acts as a cyclic antioxidant, how it stacks with other longevity ingredients for visible results, and how our anti-staining technology makes it safe for daily use, even over makeup.
You’ll learn why this spray doesn’t just hydrate, it upgrades everything that comes after it. From improved collagen signaling to enhanced barrier recovery, Blue Peptide Spray sets a new standard in functional skincare.
What's Discussed:
(00:01) Behind the Breakthrough: Why We Had to Reinvent Facial Mists(17:06) Methylene Blue: The Mitochondrial Molecule Your Skin’s Been Missing(31:20) Why This Spray Makes Every Other Product Work Better(38:00) Building an Antioxidant Network That Doesn’t Burn Out(41:36) Real Results: Hydration, Firmness, and Post-Treatment RecoveryFind more from Young Goose:
Blue Peptide Spray – Cellular hydration meets antioxidant power →Blue Peptide SprayAmplifying Essence – Prime skin for deeper absorption →Amplifying essenceThe YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram:@young_goose_skincareWed, 24 Sep 2025 - 51min - 214 - Why Collagen Doesn’t Work Without Vitamin C + Other Supplement Truths
What if your collagen cream isn’t working, because your skin doesn’t have the raw materials to use it?
In this episode of Biohacking Beauty we reveal the missing half of most people’s skincare: the internal protocol. From vitamin C as a collagen cofactor (“10x harder for your skin to build collagen without it”) to the role of omega-3s in plumping skin from the inside out, this episode lays out a step-by-step supplement strategy for real skin longevity.
We break down why oral hyaluronic acid outperforms topical forms in clinical trials, why senescent cells are not the root cause of aging (just a symptom), and how bioactives like NMN, ergothioneine, and astaxanthin actually get expressed in the skin, unlike most topicals.
We also discuss trends like matcha and how it outperforms coffee for skin health, and why oral senolytics like fisetin help eliminate zombie cells that drive inflammation and visible aging.
You don't want to miss this one!
What's Discussed:
(00:39) Why Supplements Matter More Than Serums
(03:38) The Foundational Skin Stack: C, D, E, Omegas, Collagen, HA
(19:04) Mid-Tier Bioactives: CoQ10, Curcumin, EGCG, Astaxanthin
(34:33) Advanced Longevity: NMN, Fisetin, Spermidine, Sulforaphane
(43:05) Metabolomics Testing + Personalized Skin Protocols
(52:46) Final Takeaways: Building a Skin Longevity Regimen
Find more from Young Goose:
The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareWed, 17 Sep 2025 - 52min - 213 - Leah Vairo (FilterBaby): Is Your Tap Water Aging Your Skin? Chlorine, Hard Water & NAD⁺ Depletion
What if the reason your skin barrier keeps breaking down has nothing to do with your products, and everything to do with the water coming out of your tap?
In this episode, Leah Vairo, Chief Brand Officer at FilterBaby, joins us to reveal how chlorine, hard water minerals, and hidden contaminants in your shower or sink accelerate oxidative stress, disrupt the microbiome, and drain your skin’s NAD⁺ reserves. We dive deep on how unfiltered water weakens keratinocyte activity, fuels irritation and redness, and speeds up visible aging. even if you’re using the best skincare.
You’ll discover why most shower filters don’t actually work, the lab data showing filtered water improves hydration and wound healing. Plus, Leah shares the exact filtration criteria that matter (and which ones are marketing hype), and why filtered water is the foundation for every serum and peptide you apply.
Leah Vairo is the Chief Brand Officer at FilterBaby, a company pioneering skin-first water filtration using advanced Japanese ultrafiltration membranes and activated carbon technology.
What's Discussed:
(00:03) How Tap Water Quality Affects Skin Aging and Barrier Health(08:48) Chlorine, Hard Water & Their Impact on Skin and Hair(25:21) How to Choose the Best Water Filter for Skin and Hair Health(30:38) FilterBaby Founder Story: From Skin Struggles to Water Filtration Innovation(34:44) Holistic Skincare: Water, NAD⁺, Nutrition & Lifestyle Factors(44:19) Benefits of Washing With Filtered Water for Acne, Eczema & Anti-Aging(58:48) Longevity Skincare Foundations: Sleep, Recovery & Barrier RepairFind more from Young Goose:
The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram:@young_goose_skincareLeah Vairo (FilterBaby)
Instagram: @leavairoWebsite: https://filterbaby.com Instagram:@thefilterbabyWed, 10 Sep 2025 - 54min - 212 - Dr. Vincent Pedre: Leaky Gut, Wrinkles & Inflammation — The Hidden Connection
What if the real reason your skin is aging faster has nothing to do with your skincare, and everything to do with your gut?
In this episode, Dr. Vincent Pedre, gut health expert joins us to uncover how leaky gut, dysbiosis, and hidden food sensitivities can trigger acne, eczema, redness, and premature wrinkles. We explain how gut inflammation accelerates collagen breakdown, fuels glycation, and weakens the skin barrier, and why restoring your microbiome can be more powerful than any topical cream.
You’ll discover the surprising role of pomegranate polyphenols, how certain “healthy” foods can sabotage your skin, and Dr. Pedre’s most effective tools for repairing the gut. Plus, he shares the daily habits that keep your microbiome, and your complexion, healthy, resilient, and glowing from the inside out.
Dr. Vincent Pedre, M.D., is a board-certified internist, functional medicine physician, and leading authority on the gut–skin connection. He is the founder of Pedre Integrative Health in New York City and CEO of Happy Gut Life, where he developed the Gut C.A.R.E.® Program and authored the bestselling books Happy Gut and The GutSMART Protocol.
What's Discussed:
(00:02) How Your Gut–Skin Connection Could Be Aging You Faster
(14:05) The Overlooked Link: Gut–Brain–Skin and Your Complexion
(28:30) From Cuban Espresso to Gut-Friendly Coffee: Dr. Pedre’s Innovation Journey
(36:40) Collagen, IBS, and Why Runners Should Care About Gut Health
(46:53) Daily Habits That Build (and Keep) a Happy Gut Lifestyle
Find more from Young Goose:
The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram:@young_goose_skincareFind more from Dr. Vincent Pedre:
Instagram –@drpedre
TikTok – @drpedre
YouTube –@drpedre
Website – Happy Gut Life – https://happygutlife.com
Website – Happy Gut Coffee – https://happygutcoffee.com
Wed, 03 Sep 2025 - 49min - 211 - This is Why Your NAD+ Routine Isn’t Reaching Your Skin + The Fix
There’s a point where even the best skincare starts to feel like it’s not doing enough. Serums stack up, results slow down. What no one tells you is that this might not be a product issue, it might be an energy issue. Specifically, cellular energy. NAD+.
You’ll learn why NAD+ declines with age, how that leads to slower healing, collagen breakdown, and pigmentation, and why traditional skincare can’t keep up. We explain the science behind topical NAD+ delivery, how it compares to IVs and supplements, and why your body doesn't prioritize skin when it’s low on resources.
We also break down the best NAD+ precursors (NMN vs NR vs niacinamide), how to track your NAD+ status, and which ingredients actually raise NAD+ levels in skin, not just systemically. You’ll discover how to combine fasting, HIIT, and smart supplementation to build an energy-optimized skincare routine that works from the inside out.
Plus, we reveal the research behind NAD+ Apex™, the latest innovation from Young Goose that boosts epigenetic repair and reduces wrinkle depth by 15% in just 10 weeks.
If you want your skin to keep up with your biohacking lifestyle, this episode is your protocol for recharging skin at the cellular level.
What's Discussed:
(00:06) When Your Skin Stops Responding—This Might Be Why
(16:07) The Real Way to Raise Your NAD+ (Hint: It’s Not Just Supplements)
(22:01) What Happens When You Flood Your System with NAD+
(37:32) Why Your NAD+ Supplement Isn’t Helping Your Skin
(43:52) The Skincare Ingredient Everyone’s Talking About—But Most Get Wrong
Find more from Young Goose:
The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram:@young_goose_skincareWed, 27 Aug 2025 - 49min - 210 - The Truth About Beauty Brand Buyouts (And Why We Stay Independent)
Most headlines make billion-dollar beauty acquisitions sound like the ultimate win, build fast, sell big, cash out. We see it differently. In this episode, we share why we turn down investor offers and why outside funding often marks the end of real innovation.
We break down what happens when profit-first investors take over: pressure to cut ingredient quality, cheapen packaging, and churn out unnecessary products. We explain why that goes against everything we build at Young Goose, science-backed, high-integrity formulas that put skin longevity first.
We talk about the kind of growth we do want, how we protect our creative freedom, and why staying independent keeps our research bold and our products uncompromised.
If you want to know what really happens behind the headlines, and why we believe mission matters more than the biggest buyout offer, this episode takes you inside our vision for the future.
What's Discussed:
(00:08) Why We Refuse Investor Money (Even When It’s Millions)
(15:53) The Growth Path That Keeps Our Innovation Alive
(20:40) How Our Ingredients Influence the Entire Skincare Industry
(22:31) Why We Compare Ourselves to Aesop — Not Rhodes or Rare
(24:17) The Real Reason We’re in Skincare (It’s Not the Buyout)
Find More from Young Goose
The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough →Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for →Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFri, 22 Aug 2025 - 22min - 209 - Ben Azadi: Why 93% of Americans Are Aging Too Fast + What to Do About It
What if accelerated skin aging wasn’t about skincare at all, but about your metabolism?
In this episode, we’re joined by Ben Azadi, functional health coach, founder of Keto Kamp, and author of Metabolic Freedom. We unpack the link between metabolic flexibility and youthful skin, why being “stuck” as a sugar burner accelerates aging, and how insulin resistance silently damages your collagen, nitric oxide levels, and mitochondrial health, long before it shows up in labs.
You’ll also learn how skin tags reveal insulin issues, why seed oils might be worse than cigarettes, and what AGEs (advanced glycation end products) are doing to your glow. We break down the skin effects of glucose spikes, how autophagy rejuvenates the skin from within, and why fasting might be more effective than most beauty products.
Ben Azadi is a functional health coach, founder of Keto Kamp, and author of Metabolic Freedom and Keto Flex. He lost 80 pounds in 2008 and now helps millions optimize their metabolism through keto, fasting, and root-cause healing. Ben also hosts the Metabolic Freedom Podcast and has a global following across YouTube, TikTok, and Instagram.
Let's dive in!
What's Discussed:
(00:00) Why Fast Isn’t Always Better: The surprising truth about metabolism and aging
(07:33) Sugar Is Stealing Your Glow: How glucose spikes wreck your skin from within
(14:50) Longevity vs. Performance: How to age slower without crashing your energy
(26:28) Become a Metabolic Switch-Hitter: Burn fat, not sugar, for better skin + brain health
(40:34) Protein Timing Secrets: When and how to eat for muscle, skin firmness, and insulin balance
(45:47) Mitochondria 101: The real engine behind glowing, youthful skin
(59:31) Skip the Trends: Biohacks Ben actually uses (and which ones you can ditch)
Find More from:
Young Goose
The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram:@young_goose_skincareBen Azadi:
Website: https://benazadi.com/ Instagram: @thebenazadi Book: Metabolic FreedomWed, 20 Aug 2025 - 1h 12min - 208 - Why Pigmentation Gets Worse With Age (and How to Reverse It)
Most skincare advice treats pigmentation as a surface issue, just slap on some vitamin C and SPF, right? Not quite. In this episode, we reveal the real cellular drivers behind stubborn dark spots, melasma, and post-inflammatory pigmentation, and why conventional brightening tactics often fail long-term.
We also break down how UV, blue light, and inflammation disrupt melanocyte function and why aging skin struggles to regulate melanin evenly.
This episode gives you a layered protocol, from SPF to deeper tools like NAD+, spermidine, and more, that tackles pigment at the root. We also dive into when to consider lasers, how to prepare your skin for them, and what not to do if you want long-term results without rebound pigmentation.
If you’re ready to stop managing spots and start reversing them with precision, this episode is your science-backed strategy for even-toned, resilient skin!
What's Discussed:
(00:01) Intro and Why Pigmentation Is a Longevity Issue
(04:47) How Inflammation, Hormones, and Senescence Drive Pigment
(14:27) Breakdown of Topical Actives: THDA, Kojic, Ergothionine, and More
(20:12) Using NAD+, Spermidine, and Longevity Molecules for Real Results
(25:15) When to Consider Lasers and How to Prep Your Skin
(31:31) Essential Post-Laser Care and How to Avoid Rebound Pigmentation
(36:02) Final Takeaways and Building Pigment Resistance Long-Term
Learn More from Young Goose:
The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumsUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram:@young_goose_skincareWed, 13 Aug 2025 - 31min - 207 - Dr. Vonda Wright: This Might Be the Real Reason Your Face Looks Different After Weight Loss
What if your face is aging faster because your bones and muscles are disappearing?
In this episode, we are joined by Dr. Vonda Wright, orthopedic surgeon and longevity expert, and we discuss how mobility, muscle, and bone density are the missing links in skin aging. We unpack why post-menopausal inflammation reshapes your face, how “Ozempic face” is really about tissue quality, and why lifting heavy weights might be the most effective anti-aging tool.
You’ll also learn why facial structure collapses with bone loss, how estrogen protects your skin via immune regulation, and why filler may accelerate aging long term. Dr. Wright also shares the daily habits that prevent osteosarcopenia (bone + muscle loss), how hormonal decline drives arthritis, and why unresolved inflammation ages every layer of your body, from joints to collagen.
This episode is a wake-up call for anyone treating skin from the outside in.
We Also Discuss:
(00:01) Why Skin Longevity Starts with Movement
(09:00) Inflammation: The Hidden Accelerator of Collagen Breakdown
(26:09) Muscle, Bone, and the Real Fountain of Youth
(31:23) Face Collapse: The Triangle of Beauty and Bone Loss
(41:09) Why Women Over 40 Must Lift Heavy
(52:03) The Longevity Venn: Resilience vs. Performance vs. Aging Gracefully
(01:00:40) Bone Density, Skin Firmness, and the Truth About “Ozempic Face”
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareThe YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → Spermidine SerumsDr. Vonda Wright
Book: Unbreakable: A Woman’s Guide to Aging With Power
Instagram: @drvondawright
Wed, 06 Aug 2025 - 1h 09min - 206 - Most Body Creams Are Marketing Hype and Here’s What Actually Works
Most body creams promise firmness but deliver irritation, not regeneration. That’s why in this episode, we expose the truth about popular anti-aging body ingredients like retinol, glycolic acid, and hyaluronic acid.
You’ll learn why these actives often backfire on body skin and what it actually takes to build firmness, elasticity, and resilience from the inside out. We also break down the real biology of body skin aging, including slower cellular turnover, thicker dermis structure, and reduced sebaceous gland activity. You’ll understand why hydration and exfoliation alone aren’t enough, and how to support skin with the right cellular tools.
From NAD+ and spermidine to mitochondrial antioxidants and bioavailable peptides, this episode unpacks the essential repair systems your body skin needs to stay youthful and strong.
We also reveal the formulation strategy behind the new Young Goose Body product. Designed to combat GLP-1s-related skin laxity, collagen loss, and photodamage, it delivers real change where it counts, beneath the surface.
If you’re ready to go beyond moisturizers and build a body care routine that supports longevity at the cellular level, this episode is your blueprint.
We Also Discuss:
(00:20) The Body Cream Craze, Does Any of It Actually Work?
(13:48) A Body Cream That Rebuilds Your Skin, Not Just Moisturizes
(22:25) What Happens When You Biohack Your Body Skin
(30:42) Inside the Formula: The Ingredients Changing Skin Longevity
(44:47) The One Thing That Keeps This Podcast Going (It’s Not What You Think)
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareThe YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body’s anti-aging breakthrough → Body CreamInstagram: @young_goose_skincareWed, 30 Jul 2025 - 43min - 205 - Sandra Silverman: What Aesthetics Gets Wrong About “Non-Invasive”
What if the most dangerous part of aesthetic medicine isn’t the treatment—but the hype around it?
In this episode, we’re joined by Sandra Silverman, author of From Bullshit to Botox, to break down what really works in anti-aging, and what can leave permanent damage. From botched fillers to early facelifts, Sandra shares her personal journey through almost every aesthetic procedure available and what she wishes she knew earlier.
We unpack why treatments like Sculptra, CoolSculpting, and Emsculpt are more marketing than medicine, how lymphatic stagnation and device stacking are aging your face faster, and why even top surgeons are walking away from popular injectables. We also dive into the emotional toll of aesthetic pressure, how to spot a truly skilled injector, and why internal protocols, like peptides and NAD+, often outperform external treatments.
You'll also learn about the peptides, supplements, and injections Sandra actually uses (and cycles), her top tips for facelift recovery, and why she believes lymphatic work and weight training are the most underrated longevity tools for women.
Sandra Silverman is a beauty expert and industry insider with decades of firsthand experience. Her bestselling book is a transparent, empowering guide to navigating the aesthetic world without falling for its most common traps.
We Also Discuss:
(00:01) The Most Overrated Beauty Treatments and Why You Keep Falling for Them
(09:47) Fillers, Threads, and Devices: What’s Harming More Than Helping
(18:03) How to Choose the Right Surgeon and Why Peptides Might Be More Powerful Than Botox
(24:40) Sandra’s Longevity Stack: Peptides, NAD+, and the Injections That Changed Her Skin
(28:27) Exosomes, Aesthetic Myths, and the Making of From Bullshit to Botox*
(35:44) The Emotional Cost of Aesthetic Aging and How Sandra Rebuilt Self-Worth
(44:06) Facelifts Done Right, Liposuction Regrets, and What Really Moves the Needle
Find More from Young Goose:
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFind More from Sandra Silverman:
Website: https://www.sandralenasilverman.com/
Instagram: @sandralenasilverman
Wed, 23 Jul 2025 - 1h 02min - 204 - Can Skincare Outsmart Botox? The Peptide Revolution Explained
What if your skincare could mimic Botox, without the toxins, and actively support your skin’s longevity? We joined Tony Wrighton on the Biohacking News Podcast to break down how neuropeptides, NAD+ precursors, and copper peptides are shifting skincare from cosmetic to cellular.
We explored the real science behind Botox alternatives, the critical role of mitochondrial support, and why most products miss the mark when it comes to long-term skin health.
We also shared how Young Goose began—with a failed NAD+ delivery experiment that led to a breakthrough in skin biology.
➡️ If you’re ready to treat your skin like a high-performing organ, not just a surface, this episode will change how you think about aging, resilience, and skincare.
We Also Discuss:
(00:02) Can Your Skincare Outperform Botox? Let’s Talk Peptides
(10:25) The Peptide Era: What’s Actually Working in Skincare Now
(23:50) Next-Gen Skincare: SPF That Shields You From EMFs?
(29:24) Inside the Lab: The Wildest Biohacking Skincare Tech We’re Testing
(41:16) PEMF Therapy for Skin & Allergies? Biohack or Hype?
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareTony Wrighton
Website: tonywrighton.com
Instagram:@tonywrighton
Wed, 16 Jul 2025 - 34min - 203 - Can Skincare Really Reverse Aging? Let’s Look at the Science
What if your skincare routine could do more than hydrate and smooth?
What if it could actually reprogram how your skin ages?
In this episode we break down exactly how to build a science-backed skin longevity routine—from the biology of skin aging to the ingredients and protocols that work at the cellular level. Whether you’re dealing with hyperpigmentation, acne, rosacea, or just want to slow down visible aging, this episode teaches you how to treat your skin like the intelligent, adaptable organ it is.
You’ll learn why NMN, NR, and spermidine are game-changers in topical skincare, how to layer serums correctly, and what most routines are missing when it comes to barrier support, photoprotection, and post-procedure recovery. We also talk about the exact Young Goose products we recommend for different skin concerns—and why it’s time to start choosing skincare like you choose your supplements: based on mechanism, not marketing.
➡️ If you're ready to move beyond trends and build a routine that actually enhances skin health, repair, and resilience, this one’s for you.
We Also Discuss:
01:30 – The real reason your skin ages: inside the 12 hallmarks of aging
02:21 – Why NMN, NR, and spermidine changed the skincare game
05:46 – The exact routine Anastasia recommends (even for sensitive or aging skin)
12:00 – What to add for hyperpigmentation, acne, or rosacea
24:39 – A skincare product that mimics hyperbaric chamber therapy?!
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareInstagram: @maratvnaWed, 09 Jul 2025 - 30min - 202 - The Truth About SPF: Is Higher Really Better?
Think your SPF 50 is giving you extra protection? Not exactly.
In this episode of Biohacking Beauty, we’re breaking down the truth about sunscreen—because what you don’t know might be damaging your skin. From hidden ingredients that mess with your microbiome to why higher SPF might actually give you a false sense of security, this is your no-BS guide to smarter sun protection.
We also get into how filters like oxybenzone and avobenzone can impact your skin barrier, why “broad spectrum” doesn’t always mean full protection, and why texture, finish, and reapplication matter just as much as what’s on the label.
If you care about anti-aging, barrier health, or just want to know what you’re really putting on your face every day, this episode is a must.
Tune in now!
We Also Discuss:
03:12 – Why your SPF 50 isn’t doing what you think it is
08:03 – How much sun is actually good for your skin?
17:26 – The truth about mineral vs. chemical sunscreen
32:40 – Can sunscreen cause breakouts? Here’s what’s really happening
41:03 – The skincare step most people skip for real repair
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareWed, 02 Jul 2025 - 48min - 201 - Jamie McGuire: What If the Real Problem Isn’t Your Skin... But Your Protocol?
What if your breakouts, fine lines, and melasma weren’t about finding the “perfect” product, but fixing what’s happening under the surface?
In this episode, we’re joined by Jamie McGuire, functional aesthetician and founder of Jamie Ann Aesthetics, to explore what truly personalized skincare looks like—and why most routines miss the mark.
We unpack how internal stress, diet, hormones, and nervous system dysfunction show up on your face, why you shouldn’t chase quick fixes, and how to build an anti-aging protocol that actually works. We also discuss the most common skincare mistakes keeping people inflamed, irritated, and stuck, and the real reason exfoliation might be accelerating skin aging.
You'll also learn about the products, peptides, and treatments Jamie actually recommends (and avoids), plus her top recovery tools after explant surgery—and why she believes peptides outperform most supplements.
Jamie McGuire is a licensed esthetician and gut‑health nutrition specialist with over a decade of experience. Her bold protocols have earned her a devoted online following among those seeking skin transformation that goes far beyond surface treatments.
We Also Discuss:
01:43 – Why Jamie doesn’t need to see your skin to know what’s wrong
04:52 – The one thing she tells clients to fix before skincare
11:05 – Why most men hate skincare—and what actually works for them
20:43 – The truth about anti-aging: what to use in your 30s vs. 50s
26:50 – Why exfoliating too much is aging your skin
39:04 – Are your products secretly making your skin worse?
59:50 – Her explant recovery: what worked, what didn’t, and why peptides came first
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareJamie McGuire
Website: https://jamieanne.co/
Instagram:@jamieanneaesthetics
Wed, 25 Jun 2025 - 1h 02min - 200 - Ashley Black: The Fascia Fix That Reverses Skin Aging and Pain
What if the missing key to youthful skin, pain-free movement, and true longevity wasn’t in a serum or surgery, but in your fascia?
In this episode, we’re joined by Ashley Black, fascia expert, innovator, and creator of the FasciaBlaster®, to explore why this often-ignored system may be the body’s most powerful regenerative tool.
We break down how fascia impacts skin elasticity, blood flow, and even stem cell signaling, why popular beauty devices may be doing more harm than good, and how fascia remodeling can reverse stiffness, stagnation, and aging at every level.
We also dive into Ashley’s personal journey from near-death to groundbreaking fascia research, how mechanical stimulation regenerates collagen, and why daily fascia care is the missing link in both beauty and longevity.
Ashley Black is a fascia researcher, bestselling author, inventor of the FasciaBlaster®, and founder of the Fascia Advancement Academy.
Let’s get into it.
We Also Discuss:
03:55 – Why modern medicine missed fascia’s true role
09:07 – How fascia shapes skin structure and visible aging
16:17 – Ashley’s healing journey: from chronic pain to fascia breakthroughs
26:32 – The surprising science behind the FasciaBlaster®
36:27 – How fascia influences stem cells, blood flow, and collagen
43:25 – Can mechanical stimulation really reverse skin aging?
50:19 – How emotions get trapped in fascia (and how to release them)
1:02:41 – The future of fascia research, biohacking, and beauty
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareAshley Black
Instagram:@therealashleyblackWebsite:https://www.therealashleyblack.comWed, 18 Jun 2025 - 1h 09min - 199 - Dr. Ross Carter: Is Aging Optional? The Stem Cell Fix No One Talks About
What if reversing joint pain, skin aging, and inflammation wasn’t about more supplements, but about better signals?
In this episode, we’re joined by Dr. Ross Carter, a regenerative medicine expert and founder of the Young For Life protocol, to explore how stem cells, exosomes, peptides, and biologics are shaping the future of aging.
We unpack the science of cell signaling, inflammation, and tissue regeneration, and why most people approach regenerative medicine all wrong. We dive into how perinatal stem cells work, the truth about exosomes and MMPs, why enzyme neutralization matters more than collagen creams, and what makes biohacking with biologics effective, or completely useless.
Dr. Ross Carter is a regenerative medicine pioneer, speaker, and founder of the Young For Life method.
Let’s get into it.
We Also Discuss:
00:01 — Stem Cells: Hype or the Future of Healing?
10:29 — Can You Actually Reverse Biological Age?
22:16 — Why Your Joints Aren’t Healing (and What to Do About It)
37:31 — The Wild Future of Regenerative Medicine + AI
49:50 — Who You Trust with Your Stem Cells Matters
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareDr. Ross Carter
Website: https://youngforlife.org/
Instagram: @drrosscarterllc
Instagram: @younglife
Youtube: @Youngforlifeprogram
Wed, 11 Jun 2025 - 51min - 198 - Karen Martel: The Truth About HRT, Beauty, and Aging —What Doctors Don’t Tell You
What if the secret to glowing skin, a sharper brain, and a revived sex drive isn’t more skincare, but hormone replacement therapy?
In this episode, we’re joined by Karen Martel, certified hormone specialist and founder of The Hormone Solution, to unpack the misunderstood science of beauty and aging. From pheromones and libido to collagen and facial structure, we explore how estrogen, progesterone, and testosterone shape how you look, and how you feel.
We break down how hormone loss affects everything from your skin’s elasticity to your body composition, and why most women are being gaslit out of getting the care they actually need. We also cover the truth about HRT and cancer risk, the pros and cons of oral vs. topical vs. injectable options, and how to personalize your approach for results that go deeper than just “looking good.”
Karen Martel is a certified hormone specialist and functional health practitioner. She is the host of The Other Side of Weight Loss Podcast and the founder of The Hormone Solution, where she helps women navigate perimenopause and menopause using bioidentical hormone replacement therapy (BHRT).
Let’s get into it.
We Also Discuss:
00:02 – Are we wired to chase beauty? The evolutionary biology behind attraction13:06 – How hormones secretly shape your skin, face, and sex drive23:26 – The truth about HRT, skin aging, and what most women get wrong30:42 – Menopause isn’t a decline—it’s a reset (if you do this)36:46 – What doctors get wrong about hormone therapy for women45:07 – Inject it? Rub it on? The safest (and riskiest) ways to take HRT56:32 – Using estrogen on your face? What every woman should know firstLearn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareKaren Martel:
Website:https://karenmartel.com/
Instagram:@karenmartelhormones
Wed, 04 Jun 2025 - 1h 09min - 197 - Kristin McGee: This Daily Ritual Reverses Aging More Than Any Cream
What if the key to younger skin, stronger muscles, and a sharper mind isn’t more cardio—but more connection?
In this episode, we’re joined by Kristin McGee, a nationally recognized yoga and wellness educator who bridges classical practice with modern science to help people live, move, and age better, inside and out.
We unpack the science of mindful movement and its direct impact on aging. From her days on 30 Rock to launching Peloton’s yoga platform, Kristin shares what 30+ years of teaching has taught her about resilience, skin vitality, and aging well.
We dive into how somatic movement lowers cortisol (the #1 aging accelerator), why strength training is non-negotiable after 40, and how to design a workout routine that builds collagen, not just calories burned.
Kristin McGee is a nationally recognized yoga and wellness teacher, strength coach, and author of Somatic Exercises For Dummies.
Let’s get into it.
We Also Discuss:
(00:01) Movement is medicine: how your daily habits show up on your skin
(10:37) SPF isn’t optional: the truth about screens, pollution, and premature aging
(17:12) Want better skin? Train your body and your nervous system
(25:33) Yoga = biohacking before biohacking was cool
(34:07) The anti-aging benefits no one’s talking about (but should be)
(42:30) From Peloton to personal power: building a movement that moves you
(48:33) Meditation, muscle, and aging in—not out
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareKristin McGee
Website:https://www.kristinmcgee.comInstagram:@kristinmcgeeSubstack: kristinmcgee.substack.com Book: Somatic Exercises for DummiesWed, 28 May 2025 - 1h 00min - 196 - Your Skincare Routine Is Stuck in One Phase — Your Hormones Aren't
What if your skin issues—breakouts, dullness, inflammation—weren’t random, but deeply connected to your cycle?
In today’s episode, we are sharing a recent conversation we had on the Revital Health Podcast with Jodi Duval. We dive into something I feel incredibly passionate about: how each phase of the menstrual cycle affects our skin, and how aligning our skincare rituals with those hormonal shifts can create real, visible change.
We also talk about Anastasia’s (YG Co-founder) personal postpartum skin struggles, why traditional skincare advice often fails women, and the biohacking strategies I use to support skin from the inside out. We unpack the truth behind buzzy trends like salmon sperm facials and RF microneedling, and why they’re often more harmful than helpful.
If you’ve ever felt like your skincare routine stops working mid-month, this episode will explain why—and how to fix it.
Jodi Duval is a clinical naturopath and the founder of Revital Health Clinic, specializing in integrative and functional medicine.
We Also Discuss:
00:00 – The hormone-skin connection no one’s talking about
18:14 – How to sync your skincare with your cycle
33:45 – Why sunscreen is your ultimate anti-aging hack
44:30 – What TikTok isn’t telling you about RF microneedling
53:49 – The future of skincare: metabolomics & bio-customization
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareJodi Duval
Website:https://www.revitalhealth.com.au/
Instagram: @revital_health
Wed, 21 May 2025 - 1h 02min - 195 - Joni Laiho: The #1 Mistake in Anti-Aging Skincare (Fix This First)
What if your skin problems aren’t skin-deep at all, but rooted in your gut?
In this episode, we’re joined by gut health expert Joni Laiho to explore one of the most overlooked yet powerful connections in skin longevity: the gut-skin axis. If you’re dealing with adult acne, stubborn inflammation, accelerated aging, or skin that just doesn’t bounce back, this conversation is for you.
We break down how gut dysfunction silently drives skin issues, the early signs your gut is leaking into your face (literally), and the doctor-backed protocols that can rebuild your skin from the inside out. If you’ve tried every topical, peel, or red light mask with minimal results… this might be the missing piece.
Joni is the founder of a leading gut health company focused on healing chronic conditions from the inside out.He specializes in restoring the gut-skin connection through clinical protocols and evidence-based supplements.
Let’s get into it.
We Also Discuss:
00:01 – Why your skin problems might start in your gut
08:59 – How gut bacteria shift with age, and what it means for your skin
20:32 – The most overhyped gut health supplement (it’s not what you think)
25:51 – A proven protocol for eczema, acne, and chronic skin conditions
42:49 – L-glutamine and zinc carnosine: underrated gut repair duo
52:08 – Can enzymes actually speed up skin recovery?
01:09:27: Exclusive listener discount on gut-support supplements
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareJoni Laiho
Website: https://theranordic.com/
Instagram: @theranordic
Instagram: @laihonjoni
🎁 Exclusive Discount for Listeners
Use code YG20 at checkout on https://theranordic.com/ to get 10% off your first order.
Wed, 14 May 2025 - 1h 08min - 194 - 12 Most Viral Skin Trends Debunked
In this episode, we break down some of the most viral skincare trends you see all over Instagram and TikTok, face ice baths, jelly eye patches, salmon sperm facials, red light masks, Morpheus 8, niacinamide overload, and more.
But here’s the thing: just because a trend is everywhere doesn’t mean it works, or that it supports your skin long-term.
We don’t hype or bash blindly, we give you the science-backed truth so you can make smart, informed choices about what’s actually worth your time (and money). From understanding why face ice baths aren’t the same as full-body cold therapy to why most LED face masks don’t deliver enough power to create real change, we share the clinical insights behind the hype.
This episode is for anyone who wants to cut through the noise of skincare marketing and build a routine that actually supports skin health, longevity, and cellular repair.
➡️ Tune in for honest takes, myth-busting, and a few laughs along the way.
We Also Discuss:
(00:08) 12 Viral Skincare Trends: Are They Legit or Just Hype?
(15:51) Red Light Masks: Do They Actually Work or Just Look Cool on Instagram?
(25:38) Retinol, Niacinamide, Hyaluronic Acid: What’s Worth Using (and What’s Overrated)
(34:05) Peptides & Glycolic Acid: Powerful Tools or Skin Barrier Bullies?
(38:55) The Truth About Peptides, PRP, and Those “Miracle” Anti-Aging Treatments
(53:59) Behind the Scenes: The Great Booking Mix-Up (and Some Laughs)
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareAnastasia Khodzhaeva
Instagram: @maratvna
Wed, 07 May 2025 - 44min - 193 - Dr. Melissa Cano: How to Actually Reprogram Your Skin to Act Younger (Forget Collagen!)
What if your skincare routine could actually trigger your body’s built-in anti-aging pathways? Most products just treat the surface, but aging starts much deeper, at the cellular level.
In this episode of the Biohacking Beauty Podcast, I’m talking with Dr. Melissa Cano, Director of Science at Longevity Labs and one of the smartest voices out there when it comes to spermidine, autophagy, and cellular health. Melissa has spent years teaching practitioners and biohackers how polyamines like spermidine can activate the body’s natural cleanup process, support mitochondrial health, and actually help cells function younger.
We get into why autophagy is the key to skin renewal, why spermidine levels drop as we age, and how to use it (internally and topically) for real results. We also dig into what the latest research says about spermidine for gut health, sleep, hair—and why I believe it’s one of the most important molecules in longevity science today.
Dr. Melissa Cano is the Director of Science at Longevity Labs. Dr. Melissa is recognized for her work helping biohackers, clinicians, and health enthusiasts understand how molecules like spermidine support autophagy, mitochondrial function, and healthy aging.
Get 20% off on spermidinelife.us with code YOUNGLIFE
We Also Discuss:
(00:01) Why spermidine might be the most important longevity molecule
(05:13) Autophagy: the real anti-aging mechanism
(14:38) Why fasting isn’t enough without spermidine
(25:10) How spermidine boosts collagen and skin renewal
(31:20) The skin microbiome + topical spermidine connection
(55:48) How long until you see results?
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareDr. Melissa Cano
Website: https://spermidinelife.us/ Instagram: @spermidinelife.usWed, 30 Apr 2025 - 58min - 192 - 7 Botox Myths You’ve Believed – UNTIL NOW
In today’s episode, Anastasia and I are diving into a topic that’s on everyone’s lips—Botox. It’s become a standard in many beauty routines, but the truth is, Botox isn’t as simple as it’s made out to be. While it can smooth out wrinkles, repeated use can actually change the way your face moves and functions, leading to long-term issues like muscle atrophy and loss of natural expression.
We’re not here to scare you, but to arm you with the knowledge you need to make informed, empowered decisions about your skin. We’re breaking down 7 key facts about Botox you NEED to know, including why overuse could mess with your facial muscles, and why it’s not the “preventative” miracle some people think it is.
Botox is a tool—use it wisely, and with the right approach. Tune in for a smarter, more sustainable approach to aging. This one’s for anyone who’s had Botox, is thinking about it, or just wants to understand how it works.
We Also Discuss:
00:01 - The Truth About Botox: What Most People Don’t Know
06:12 - How Botox Alters Facial Movements Over Time
12:45 - The Concept of “Perception Drift” and Why It Matters
18:30 - Botox and Muscle Atrophy: What Happens After Years of Use
25:10 - How Botox Affects Facial Asymmetry and Expression
32:05 - The Importance of Giving Your Face a Break
40:40 - Combining Botox with Other Treatments for Better Results
48:55 - Why Botox Isn’t Always Preventative (And What You Should Do Instead)
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareAnastasia Khodzhaeva
Instagram: @maratvna
Wed, 23 Apr 2025 - 22min - 191 - This is Why Your Neck Needs MORE Care Than Your Face!
In today’s episode, Anastasia and I are tackling a topic that doesn’t get enough attention in skincare: your neck and chest. These areas age faster than your face, and most people completely overlook them in their routines. But why? The skin here is thinner, less hydrated, and more vulnerable to environmental stress. Gravity, sun damage, and even posture all contribute to crepey skin and sagging.
We’re diving into the biology of why the neck and chest age faster and what you can do about it. We’ll talk about essential strategies to keep your skin firm, hydrated, and youthful, including the importance of SPF, collagen-boosting ingredients, and why facial exercises matter. Plus, we’re introducing our game-changing Youth Firming Neck and Chest Cream—designed specifically for these delicate areas.
If you want to protect your neck and chest like you protect your face, this episode is for you!
We Also Discuss:
(00:16) Why Your Neck Ages Faster Than Your Face
(12:25) The Hidden Triggers That Age Your Skin
(19:14) Protect Your Neck and Chest Like Never Before
(28:32) The Truth About Invasive Treatments vs. Topical Solutions
(41:57) Vitamin C: The Skincare Miracle You’ve Been Overlooking
(49:57) How Antioxidants and Red Light Can Revitalize Your Skin
(01:02:25) The Next Big Thing in NAD Skincare: Innovation and a Challenge
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareSources
Wed, 16 Apr 2025 - 1h 00min - 190 - 5 Ways Red Light Therapy Can Fail You If You’re Not Careful
Hey everyone, welcome back to Biohacking Beauty! In today’s episode, we’re diving into red light therapy, one of the most science-backed tools for skin rejuvenation. But not all devices are created equal. I’ll break down the top five things you need to know before investing in a red light therapy device.
We’ll start with the science behind red light therapy, from wavelengths to irradiance, and how these factors impact skin health. I’ll also explain why certain devices fall short and how to identify the ones that truly deliver results. Plus, I’ll touch on the importance of build quality, user experience, and safety when selecting your device.
This episode is for anyone looking to harness the power of red light therapy to improve skin texture, reduce wrinkles, and boost collagen production. Let’s dive in and learn how to choose the right device for radiant, youthful skin.
Let's dive in!
I Also Discuss
(00:16) Understanding Red Light Therapy Devices
(08:58) Selecting an Effective Red Light Device
(12:05) How Red Light Therapy Enhances Your Skincare Routine
(21:51) Effective Red Light Therapy Device Selection
Sources:
Learn More About Young Goose:
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareWed, 09 Apr 2025 - 19min - 189 - These Invisible Forces Are Aging Your Skin Faster Than You Think
Hey everyone, welcome back to Biohacking Beauty! In this episode, we’re diving deep into a truth most skincare routines ignore: your environment might be aging you faster than time ever could.
We start with a story of two identical twins, same genes, same skincare habits, but drastically different aging outcomes. Why? One lived surrounded by clean nature. The other, in an urban jungle filled with air pollution, EMFs, blue light, and toxic stress. The difference wasn’t just visible, it was cellular.
In this episode, I explore how environmental stressors silently sabotage your skin by disrupting three critical biological systems. First, they deplete NAD+, second, they interfere with your epigenetic expression. And third, they impair autophagy, your body’s natural recycling system.
I’ll walk you through the Skin Longevity Matrix, a radically different framework we developed at Young Goose to reverse aging from the inside out, by supporting your skin at its biological roots, not just masking symptoms at the surface.
Let's dive in!
I Also Discuss:
(00:02) Uncovering the Secrets of Skin Aging
(02:33) Your Skin Is a Storybook of Environmental Damage
(07:14) The 3 Silent Saboteurs Behind Premature Aging
(18:48) Revolutionizing Skin Aging With Cellular Rejuvenation
Learn More About
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareWed, 02 Apr 2025 - 20min - 188 - Dr. Jessica Shepherd: The Shocking Truth About Menopause & Skin Aging (Most People Get This Wrong!)
Most people think menopause is just about hot flashes and mood swings—but what if I told you it’s actually one of the biggest drivers of skin aging? From collagen loss to increased sensitivity, breakouts, and inflammation, hormonal shifts can make you look older, faster. And yet, no one is talking about it.
To uncover the real impact of menopause on skin health (and what you can do about it), I’m joined by Dr. Jessica Shepherd, an OB-GYN, menopause expert, and founder of Sanctum Med & Wellness. She’s on a mission to rewrite the menopause narrative, showing women how to take control of their skin, hormones, and longevity.
In this episode, we dive into the real impact of estrogen decline on skin aging, why some women experience sudden breakouts or rosacea in midlife, and how hormone replacement therapy (HRT) can play a role in both skin health and longevity. We also explore the connection between gut health, inflammation, and skin vitality, as well as the cutting-edge treatments and biohacking strategies that are changing the game for menopausal women.
Dr. Shepherd is also the author of Generation M, a book that serves as both a medical and lifestyle guide for women navigating this stage of life. She breaks down why menopause isn’t just a phase, it’s a long-term shift that requires a strategic approach to aging well.
If you’re looking for science-backed strategies to optimize your skin, hormones, and overall well-being through perimenopause and menopause, this episode is a must-listen.
We Also Discuss:
(00:02) Women's Health and Skin Aging
(09:31) Hormone Therapy and Skin Rejuvenation
(17:29) Effective Skincare Ingredients and Approaches
(21:46) Longevity and Gut Health for Skin
(31:42) Importance of Sleep for Longevity
(39:08) Future of Women's Health Therapies
(52:16) Embracing Aging With Agency and Curiosity
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareDr. Jessica Shepherd
➡️Exclusive for Biohacking Beauty Listeners
If you’re serious about optimizing your skin health and hormones, here’s something special for you: Anyone who visits Dr. Jessica Shepherd’s clinic, and mentions the Biohacking Beauty Podcast will receive a complimentary skin consultation.
Instagram:@jessicashepherdmdTwitter:@JShepherd_MDLinkedIn:Jessica Shepherd, MD, MBA, FACOGBook: Get Dr. Jessica Shepherd’s Book Generation MWed, 26 Mar 2025 - 53min - 187 - Why Red Light Therapy in Your Skincare Routine Isn’t Enough (Until You Add THIS)
Your skin is a reflection of your cellular health—but what if you could influence it on a deeper level? Red light therapy (photobiomodulation) is changing the way we think about aging, collagen production, and inflammation. In this episode of the Biohacking Beauty podcast, Amitay Eshel and Anastasia Khodzhaeva, co-founders of Young Goose Skincare, break down how red light therapy impacts skin longevity, from boosting collagen to reducing inflammation. They explain what determines individual results, the common mistakes people make, and how to get the most out of this powerful technology.
But here’s the truth that not everyone knows: using red light therapy alone isn’t enough. To truly support skin regeneration, it needs the right biochemical environment. That’s where our newest LADR serum comes in—optimizing ATP production and reducing oxidative stress to help your skin work smarter. We break down exactly how to integrate this into your skincare routine, from layering antioxidants to timing your treatments for maximum benefit.
We Also Discuss:
(04:36) Why Red Light Therapy Is a Game-Changer For Your Skin
(12:48) The Skincare Ingredients That Actually Work with Red Light Therapy
(23:06) Creating a Red Light Therapy Skin Care Routine
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareWed, 19 Mar 2025 - 26min - 186 - The TRUTH About Botox They Don't Want You To Know
Welcome back to Biohacking Beauty! In this episode, we tackle the controversial topic of Botox and explore effective alternatives for those seeking more natural approaches to youthful skin. Young Goose co-founder Anastasia Khodzhaeva opens up about her personal experience with Botox treatments and why they didn't work for her, while we discuss the science behind various alternatives.
Rather than demonizing Botox, we examine both sides of this polarizing beauty topic, offering insights for those who use Botox and those looking for different options. From peptides and cellular repair compounds to professional treatments and at-home techniques, we break down what actually works when you're seeking youthful skin without neurotoxins.
Anastasia shares her journey through postpartum skin changes and how she found effective alternatives that worked for her unique situation. We also discuss how Young Goose formulations support skin regeneration at the cellular level, offering a different approach to common signs of aging. If you’ve ever wondered if Botox is for you, this is an episode you don’t want to miss.
We Also Discuss:
(04:31) Defining what we mean by "Botox alternatives"
(06:45) Anastasia's personal journey with Botox and TMJ
(19:01) How Botox works and potential side effects
(25:17) The debate around Botox as a "preventative" treatment
(32:11) Neuropeptides and how they differ from Botox
(36:31) NAD precursors and cellular repair mechanisms
(45:20) The role of autophagy in skin rejuvenation
(45:47) Red light therapy benefits and limitations
(51:03) Facial taping, massage, and professional treatments
(56:54) Finding a balanced approach that works for you
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareWed, 12 Mar 2025 - 55min - 185 - The Silent Killer Inside Your Cells (And How to Fight Back)
Hey everyone, welcome back to Biohacking Beauty! Today, we’re exploring one of the most fundamental mechanisms of aging—telomeres. These nucleotide sequences at the ends of our chromosomes act as protective caps, preserving DNA integrity during cell division. However, each time a cell replicates, telomeres shorten, eventually leading to cellular senescence, dysfunction, or apoptosis.
In this solo episode, I’m breaking down the molecular mechanisms behind telomere shortening, how factors like oxidative stress, inflammation, and metabolic dysfunction accelerate the process, and, most importantly, what we can do to slow or even reverse this decline.
We’ll dive into the latest research on NAD metabolism, autophagy, telomerase activation, and epigenetic regulation, as well as practical interventions like targeted supplementation, lifestyle modifications, and advanced skincare strategies that support telomere stability.
If you’re serious about cellular longevity, DNA repair, and optimizing your skin health at the deepest level, this episode is a must-listen.
Let’s get into it!
I Also Discuss:
(01:33 - 02:15) What Are Telomeres and Why Do They Matter?
(03:42 - 04:19) The Hidden Danger of Cellular Aging
(08:48 - 09:12) Can You Actually Reverse Telomere Shortening?
(12:45 - 13:27) Why Your Skin Shows Signs of Aging First
(10:41 - 11:12) The Best Supplements to Protect Your DNA
Learn More About
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFri, 07 Mar 2025 - 18min - 184 - Dr. Stephanie Venn-Watson: The Essential Fat That Reverses Aging—Why No One’s Talking About It?
Today, we’re diving into a discovery that could reshape how we think about aging—C15, a newly identified essential fatty acid that plays a crucial role in cellular resilience, inflammation control, and longevity.
For decades, we’ve been told to avoid saturated fats, but what if that advice led to widespread nutritional deficiencies? Dr. Stephanie Venn-Watson, a veterinary epidemiologist and co-founder of Fatty15, uncovered C15’s role in strengthening cell membranes, reducing oxidative stress, and even influencing epigenetic aging—all from studying long-lived Navy dolphins.
In this episode, we break down how C15 protects against cellular fragility, fights ferroptosis (a newly identified form of cell death), and why it’s critical for maintaining healthy skin and metabolic function. We’ll also explore why modern diets have nearly eliminated this nutrient—and what that means for your long-term health.
Dr. Venn-Watson’s research spans over 100 peer-reviewed studies, leading to the first essential fatty acid discovery in nearly a century. Her work is redefining how we approach nutrition, longevity, and skin health at the molecular level.
We Also Discuss:
(00:01) Discovery of C15 Fatty Acid Benefits
(08:37) Importance of C15 Fatty Acid
(19:09) C15 Fatty Acid Impact on Health
(36:11) Uncovering the Role of C15
(45:10) The Case for C15 Fatty Acid
(53:48) Optimal Absorption of C15 Fatty Acid
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareStephanie and Fatty15
Website: https://fatty15.com/
Instagram: https://www.instagram.com/fatty15/
LinkedIn: https://www.linkedin.com/in/stephanievennwatson/
Wed, 05 Mar 2025 - 1h 05min - 183 - Stop Wasting Money! THIS Is Real Anti-Aging…
For years, skincare has been about quick fixes, hydration, plumping, and surface-level treatments that make your skin look better but don’t actually reverse aging. But what if the future of skincare wasn’t about temporary effects, but about reprogramming your skin at the cellular level?
In this episode of Biohacking Beauty, I take a deep dive into longevity skincare and the science behind true skin rejuvenation. We’re going beyond the outdated skincare model and breaking down the Skin Longevity Matrix, a biohacking approach designed to restore youthful function from within.
I cover why NAD+ is the "molecule of life" and a critical driver of skin repair, helping cells recover from oxidative stress and damage. We’ll explore how spermidine activates autophagy, the body’s natural detox system, to clear out aging cells and renew skin from the inside out.
I’ll also explain the essential role of copper peptides in collagen remodeling and why they’re key for structural skin regeneration. Plus, we’ll dive into the problem with traditional vitamin C and why advanced forms like MAP and THDA provide superior antioxidant protection without causing oxidative stress. Finally, I’ll break down how eliminating senescent “zombie cells” can dramatically slow down aging and prevent chronic inflammation in the skin.
This is the next frontier of skincare—science-backed, longevity-focused, and designed to make your skin act younger, not just look younger.
If you’re ready to upgrade your skincare routine with the latest breakthroughs in anti-aging science, this episode is for you!
I Also Discuss:
(00:02) Biohacking Beauty
(05:18) Why NAD+ Is the Foundation of Youthful Skin
(12:56) How Spermidine Supercharges Skin Detox & Renewal
(19:09) Revitalizing Skin With Key Skincare Molecules
(27:41) The Truth About Vitamin C in Skincare
(32:23) How to Eliminate Senescent “Zombie” Cells for Younger Skin
Learn More About
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFri, 28 Feb 2025 - 34min - 182 - Nick Engerer: Your Skincare Routine Won’t Fix THIS Aging Problem
Today, we’re diving into something that goes way beyond skincare, how your skin is actually a powerful window into your overall health and longevity. Most people think of aging as just wrinkles and fine lines, but the reality is that what’s happening on the surface is a direct reflection of what’s going on at the cellular level.
To explore this, I’m joined by Nick Engerer, a longevity scientist and the founder of A Longer Life, where he helps people take a data-driven, strategic approach to optimizing health and aging. Nick’s work is all about cutting through the noise, moving beyond trends and hype to focus on what actually works when it comes to extending healthspan and improving quality of life.
In this episode, we get into why your skin and hair are some of the most revealing biomarkers of aging, how UV exposure accelerates biological aging in ways most people don’t realize, and what you can do to slow that process down. We also tackle one of the biggest challenges in wellness today, decision fatigue. With endless options for supplements, treatments, and interventions, how do you know what’s actually worth your time and money?
Nick’s background is unique, he started as a solar radiation scientist before pivoting into longevity science, bringing a data-driven approach to proactive health. Through A Longer Life, he’s building a framework to help people apply longevity strategies in a practical, sustainable way.
If you want to learn how to take control of your skin health, optimize your longevity, and navigate the overwhelming world of wellness with confidence, this episode is for you.
We Also Discuss:
(00:00) The Essence of Biohacking
(14:36) Investing in Longevity and Skincare
(22:16) The Science of Skincare and Aging
(31:45) Reproductive Signals and Longevity Strategy
(45:03) Navigating Wellness and Longevity Overwhelm
(54:21) Optimizing Evening Routine for Wellness
(01:00:12) Exploring New Mindset Course
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareNick Engerer
Wed, 26 Feb 2025 - 1h 00min - 181 - The Hidden Science of Skin Aging (And How to Reverse It)
For years, skincare has focused on surface-level solutions, moisturizers, retinol, collagen creams… but what if we told you that true skin rejuvenation starts at the cellular level? Traditional skincare is designed to mask aging, but new research in longevity science reveals that the root causes of aging go much deeper.
In this episode of Biohacking Beauty, I break down the real drivers of skin aging, from mitochondrial dysfunction and NAD decline to epigenetic shifts, senescent cells, and impaired autophagy. I also discuss why most anti-aging products don’t actually reverse aging, and how cutting-edge biohacking ingredients like NAD+, spermidine, copper peptides, and advanced vitamin C are changing the game.
This is the future of skincare, moving beyond temporary fixes and truly reprogramming skin cells for longevity.
If you’ve ever wondered why your skin isn’t responding to traditional skincare, or how you can actually slow down and even reverse the aging process, this episode is for you!
I Also Discuss:
(00:01) The Science of Ageless Skin
(04:54) Your Mitochondria Are Aging Your Face
(12:21) Can You Actually Reverse Skin Aging?
(17:21) The Truth About Skincare Lies
Learn More About
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFri, 21 Feb 2025 - 28min - 180 - Hannah Went: Your Skincare Routine Won’t Fix THIS Aging Problem
Welcome back to Biohacking Beauty! Today, we’re diving into the cutting-edge science of biological vs. chronological aging and how epigenetic testing is revolutionizing the way we understand skin longevity. Aging isn’t just about the number of birthdays you’ve had—it’s about how your cells are aging at the molecular level. And now, thanks to advancements in epigenetics and AI-driven diagnostics, we can measure and even influence that process.
In this episode, I sit down with Hannah Went, an expert in biological age testing and the Director of Operations at TruDiagnostic, a leading epigenetics company. We explore how biological aging manifests in the skin, why epigenetic markers are more predictive of health than genetics, and how personalized interventions can actually slow or even reverse aging at the cellular level.
Hannah also shares groundbreaking research on how lifestyle choices, like diet, sleep, and even skincare, can alter gene expression and influence the rate at which we age. Plus, we discuss how advanced testing methods can provide real-time feedback on how well anti-aging interventions are actually working. If you’ve ever wanted to take a data-driven approach to longevity, this episode is packed with insights you won’t want to miss.
Hannah Went is the Director of Operations at TruDiagnostic, a company at the forefront of biological age testing and longevity research. With a background in epigenetics and functional medicine, she’s dedicated to helping individuals track and optimize their health using cutting-edge diagnostic tools.
We Also Discuss:
(00:01) Epigenetics and Biological Age Testing
(13:47) Aging and Skin Link Exploration
(26:13) Genetic Influence on Phenotype and Aging
(31:37) Aging, Skin Health, and Lifestyle Factors
(44:43) At-Home Genetic Testing Support
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareHannah Went
Website: everythingepigenetics.com Instagram: @everythingepigeneticsWed, 19 Feb 2025 - 44min - 179 - This is Why Sunscreen Alone Won’t Save Your Skin
Have you ever wondered why traditional sunscreens aren’t enough to protect your skin from all forms of light damage? In this episode of Biohacking Beauty, I’m sitting down with Jamie McGuire to break down the truth about blue light exposure, SPF, and effective melasma protocols.
We dive into why hyperpigmentation often worsens with artificial light exposure, the importance of full-spectrum protection, and how Young Goose’s innovative formulas address common skin concerns like melasma, sensitivity, and inflammation. Plus, we tackle the "clean beauty" debate—are some ingredients being unfairly criticized?
Jamie McGuire is a skincare expert with over 15 years of experience in personalized skincare protocols. Her holistic approach focuses on helping clients achieve long-term skin health through science-backed recommendations and innovative biohacking products.
Whether you’re dealing with melasma or looking for smarter protection against blue light, this episode offers valuable insights and real solutions to refine your routine for radiant, resilient skin.
We Also Discuss:
46:04 - 49:10 – The Reality of "Clean Beauty": Understanding Controversial Ingredients
49:11 - 50:39 – Melasma and Hyperpigmentation: Understanding the Triggers
50:40 - 54:30 – Melasma Protocol Breakdown: Step-by-Step Routine
54:31 - 57:07 – The Power of BioShield SPF 40: Protection Beyond UV Rays
57:08 - 01:00:13 – Why Retinol Sensitivity Happens (and How Bioretinol Prevents It)
01:00:14 - 01:02:23 – Red Light Therapy Synergy with Green Tea Phyto Serum
Learn More About
Jamie McGuire
Instagram: @jamieanneaestheticsWebsite: www.jamieanne.co/Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareFri, 14 Feb 2025 - 16min - 178 - Dr. Scott Sherr: Stress & Light on Your Skin Are Aging Your Entire Body
Most people don’t think about their skin until they have to. The reality is, by the time we notice fine lines, dullness, or inflammation, deeper processes have already been at play for years. But what if your skin isn’t just reflecting aging? What if it’s reflecting your overall health, stress levels, and even brain function?
In this episode of Biohacking Beauty, I sit down with Dr. Scott Sherr to uncover the fascinating connection between your skin and brain, a relationship most people don’t even realize exists. This conversation originally took place on The Smarter Not Harder Podcast, where Scott and I explored the skin-brain axis and how your skin is more than just a barrier, it’s an active communicator with your nervous system, influencing everything from inflammation to stress resilience and even cognitive function.
We also tackle some of the biggest misconceptions in skincare, like why hydration doesn’t actually come from the outside, how sun exposure impacts your skin at a cellular level, and the surprising ways senescent cells in your skin accelerate whole-body aging. Plus, we break down the latest science on hormones, collagen production, and microbiome health, and how all of these factors impact how your skin ages.
Dr. Scott Sherr is the host of the Smarter Not Harder Podcast anda physician specializing in health optimization, hyperbaric therapy, and longevity medicine. As the founder of Integrative HBOT and a leading expert in performance medicine, he helps individuals leverage cutting-edge science to enhance vitality, slow aging, and optimize brain and body function.
If you want to know how to extend your skin’s youthfulness beyond just skincare products, this is an episode you won’t want to miss!
We Also Discuss:
(00:00) Skin-Brain Axis
(12:43) Skin Aging and Evolution
(27:15) Skin Microbiome and Postbiotics
(35:39) Hormones, Skin Aging, and Repair
(49:16) Living Smarter, Not Harder
(56:07) Sunscreen and Skin Protection
(01:01:36) Vitamin C and Spermidine in Skincare
(01:10:16) Skin Health and Spermidine Benefits
(01:16:43) Biohacking Beauty Podcast and Skincare
Learn more about:
Young Goose
Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off athttps://www.younggoose.com/ Instagram: @young_goose_skincareScott Sherr
Website: https://home-sf.co/ Instagram: https://www.instagram.com/drscottsherr/ Youtube: Smarter not Harder PodcastWed, 12 Feb 2025 - 1h 21min
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