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Lost Women of Science

For every Marie Curie or Rosalind Franklin whose story has been told, hundreds of female scientists remain unknown to the public at large. In this series, we illuminate the lives and work of a diverse array of groundbreaking scientists who, because of time, place and gender, have gone largely unrecognized. Each season we focus on a different scientist, putting her narrative into context, explaining not just the science but also the social and historical conditions in which she lived and worked. We also bring these stories to the present, painting a full picture of how her work endures.
- 159 - A pioneer behind x-ray crystallography, Isabella Karle
In high school, Isabella Karle had to take a science class to fulfill a prerequisite. She chose chemistry at random. Karle would go on to become one of the most important chemists of her time, doing groundbreaking research in the field of X-ray crystallography. Her discoveries in the mid 1950s are a key reason many modern-day pharmaceuticals are available on pharmacy shelves. But Karle’s collaborator–her husband, Jerome–would eventually receive the Nobel Prize in Chemistry for work Isabella also achieved.
Thu, 06 Aug 2026 - 36min - 158 - Conversations: The Rediscovery of I Who Have Never Known Men
In this episode of Lost Women of Science Conversations, host Elah Feder explores the remarkable resurgence of I Who Have Never Known Men, Jacqueline Harpman’s 1995 novel that went largely unnoticed for decades before becoming an international sensation. Harpman was a psychoanalyst and her training informed the book’s speculative fiction, dystopian, and science fiction genres. Elah first speaks with award-winning translator Ros Schwartz, who translated the novel into English twice –once in 1997 and again in 2022, when a new edition helped introduce Harpman’s work to a new generation of readers. Later, Elah is joined by Susan Watkins, Professor of Women’s Writing at Leeds Beckett University, to discuss the novel’s themes of resilience, isolation, and survival, and why this once-overlooked book is resonating so strongly with readers today.
Thu, 16 Jul 2026 - 28min - 157 - Best Of: The Woman Who Demonstrated the Greenhouse Effect
In 1856, decades before the term “greenhouse gas” was coined, Eunice Newton Foote demonstrated the greenhouse effect in her home laboratory. She placed a glass cylinder full of carbon dioxide in the sun, and found that it heated up much faster than a cylinder of ordinary air. Her conclusion: more carbon dioxide in the atmosphere results in a warmer planet. Several years later, a British scientist named John Tyndall conducted a far more complicated experiment that demonstrated the same effect and revealed how it worked. Today, he’s widely known as the man who discovered the greenhouse gas effect. There’s even a crater on the moon named for him! Eunice Newton Foote, meanwhile, was lost to history—until an amateur historian stumbled on her story.
Thu, 25 Jun 2026 - 31min - 156 - La mujer que demostró el efecto invernadero
En 1856, décadas antes de que se acuñara el término “gas de efecto invernadero”, Eunice Newton Foote demostró el efecto invernadero en su laboratorio casero. Colocó un cilindro de vidrio lleno de dióxido de carbono al sol y observó que se calentaba mucho más rápido que un cilindro con aire común. Su conclusión: más dióxido de carbono en la atmósfera da lugar a un planeta más cálido. Años más tarde, un científico británico llamado John Tyndall realizó un experimento mucho más complejo que demostró el mismo efecto y explicó su funcionamiento. Hoy en día, Tyndall es ampliamente reconocido como el hombre que descubrió el efecto invernadero. ¡Incluso hay un cráter en la luna que lleva su nombre! Mientras que Eunice Newton Foote fue olvidada por la historia… hasta que un historiador aficionado redescubrió su legado.
Thu, 25 Jun 2026 - 36min - 155 - Tilly Edinger: The Paleoneurologist Saved By Her Science
How much can you understand about a brain when that brain is long gone? Tilly Edinger, a Jewish paleontologist, used fossilized skulls to study the evolution of brains. That research allowed her to escape Nazi Germany in 1939, and create a new subdivision of paleontology, paleoneurology.
Thu, 11 Jun 2026 - 31min - 154 - Kamala Sohonie: The Chemist who Wanted to Feed a Nation
In 1930s India, Kamala Baghvat dreamed of working alongside the world's greatest scientific minds. But she was repeatedly told “no” when she tried to work in the then male dominated field. Inspired by Gandhi, she used nonviolent protest to pry her way into some of India’s top laboratories. She became the first Indian woman to earn a PhD in biochemistry, and eventually, the first woman to lead India's Royal Institute of Science. Baghvat’s career centered around a topic she was passionate about: solving India’s malnutrition crisis.
Thu, 28 May 2026 - 42min - 153 - Sharla Boehm: The Programmer Whose Code Underpins the Internet
Sharla Boehm earned a teaching degree from UCLA before channeling her talent for math into computer programming. While working at the Rand Corporation, she built a ground-breaking simulation, originally conceived to strengthen military communications during the Cold War. The simulation –and her work– would ultimately lay the foundation for the modern internet.
Thu, 14 May 2026 - 26min - 152 - Best Of: Chemistry Professor and Crime Buster: The Remarkable Life of Mary Louisa Willard
“The only time I ever saw something that I thought was abnormal…there was a human arm in the refrigerator,” said J. Peter Willard about his aunt, Mary Louisa Willard. Otherwise, he insisted, she was “very normal.” But Mary Louisa Willard, a chemistry professor at Pennsylvania State University in the late 1920s, left a strong impression on most people, to say the least. Her hometown of State College, Pennsylvania, knew her for stopping traffic in her pink Cadillac to chat with friends, and for throwing birthday bashes for her beloved cocker spaniels. Police around the world knew her for her side hustle: using chemistry to help solve crimes.
Thu, 30 Apr 2026 - 30min - 151 - Profesora de química y caza criminales: La extraordinaria vida de Mary Louisa Willard
“La única vez que vi algo que me pareció anormal… había un brazo humano en el refrigerador”, dijo J. Peter Willard sobre su tía, Mary Louisa Willard. Por lo demás, insistió, era “muy normal.” Pero Mary Louisa Willard, profesora de química en la Universidad Estatal de Pensilvania a finales de la década de 1920, dejó una fuerte impresión en la mayoría de las personas. Su ciudad natal, State College (Pensilvania), la conocía por detener el tráfico en su Cadillac rosa para saludar a sus amistades, y por organizar fiestas de cumpleaños para sus queridos perritos cocker spaniels. La policía la conocía por su oficio secundario: usar la química para resolver crímenes.
Thu, 30 Apr 2026 - 31min - 150 - Elizabeth Roboz Einstein: The Determined Genius Behind a Multiple Sclerosis Breakthrough
Elizabeth Roboz Einstein’s life was shaped by the forces of history. She studied bioorganic chemistry at the University of Vienna in the 1920s and then left her home country of Hungary during World War II, before German troops invaded — practically a miracle for a single, Jewish woman. In the U.S., she blazed a trail in the brand new field of neurochemistry; her seminal research into multiple sclerosis (MS) unlocked key findings that would make effective medical treatments for MS possible.
Thu, 16 Apr 2026 - 38min - 149 - Conversation: If I Am Right, and I Know I Am: Inge Lehmann, the Woman Who Discovered Earth’s Innermost Secret
In this episode of Lost Women of Science Conversations, host Carol Sutton Lewis speaks with science writer Hanne Strager about her biography of Inge Lehmann, the pioneering Danish seismologist who discovered that Earth has a solid inner core.. Largely unknown outside scientific circles, Lehmann fundamentally transformed our understanding of what lies at the heart of our planet. She did this in 1936 by identifying anomalies in earthquake waves that others had overlooked. At the time, scientists believed Earth’s core was entirely liquid. Lehmann proposed instead that a solid inner core lay hidden within it — a groundbreaking insight that reshaped geophysics. In revisiting Lehmann’s story, Strager highlights that Lehmann’s legacy is one of resilience and perseverance — proof that early setbacks do not define a life, and that brilliance can flourish, even later in life.
Thu, 02 Apr 2026 - 36min - 148 - BONUS: Agnes Pockels and the Kitchen Sink Myth
This bonus episode is a co-production with Distillations, a podcast produced by the Science History Institute. Agnes Pockels did pioneering work in surface science. Her invention, the Pockels Trough, became the basis for an instrument that helped Katherine Burr Blodgett and Irving Langmuir make discoveries in material science that quietly shape our everyday world. But the way we talk about Agnes’s life and work often falls back on familiar tropes about women’s domestic roles, assumptions about how science gets done, and what it looked like to do science as a woman in the 19th century. Agnes's story invites us to rethink how we define success for scientists. Is our definition too narrow? And what might we gain if we crack it open a bit wider?
Thu, 19 Mar 2026 - 37min - 147 - Layers of Brilliance: Vanishing Act -- Episode Six
How is a legacy preserved, and how is someone forgotten? Determined to make a final name for himself, Irving Langmuir ventures into science that even he might classify as pathological wishful thinking, while Katharine continues her work as the diligent experimenter. But her contributions faded from both the company’s and the public’s memory. We go to visit her, to say good-bye – and we look at the wisdom she imparted to the next generation of inquiring minds.
Thu, 12 Mar 2026 - 37min - 146 - Layers of Brilliance: The Self You Have to Live With - Episode Five
Katharine’s relatives lead the production team to a collection of papers and artifacts stored in a New England storage unit, revealing an inner struggle she kept carefully out of sight – even as she was making history in the laboratory.
Thu, 05 Mar 2026 - 29min - 145 - Layers of Brilliance: The Breakthrough - Episode Four
The 1930s prove to be an exceptional decade for research at The General Electric Company. Katharine Burr Blodgett works closely alongside her boss, Irving Langmuir who, in 1932, wins the Nobel Prize for Chemistry. In 1938, Katharine’s meticulous experiments with thin film coatings on solid surfaces lead to her most important breakthrough: non-reflecting glass. The General Electric Company’s public relations machine kicks into high gear. Katharine becomes an overnight sensation, both in the scientific community and in the press, which dub her discovery “invisible glass.” The assistant to the Nobel Prize winner, long invisible herself, takes center stage.
Thu, 26 Feb 2026 - 25min - 144 - Layers of Brilliance: The Air She Breathed -- Episode Three
The only woman in a laboratory filled with men, Katharine Burr Blodgett soon becomes indispensable as an assistant to The General Electric Company’s most famous scientist, Irving Langmuir. Their working relationship is an elegant symbiosis: her forte is experimentation, his is scientific theory. We follow their partnership as they successfully find ways to build a better lightbulb but Langmuir stumbles with an off-the-wall theory of matter. All the while, Katharine builds her life in Schenectady: going to church, making new friends, falling in love. In 1924, she embarks on a new journey to the University of Cambridge, where she studies with some of the most prominent physicists of the 20th century.
Thu, 12 Feb 2026 - 39min - 143 - Layers of Brilliance: The 'House of Magic' -- Episode Two
Katharine Burr Blodgett arrives at The General Electric Company’s legendary research laboratory in Schenectady, New York, known as the “House of Magic.” She was just 20 years old when she entered a world built almost entirely for men. She joins as assistant to the brilliant and eccentric Irving Langmuir, a star chemist whose fundamental work in materials science and light bulbs would bring fame to him, and fortune to GE. The General Electric Company was an obvious choice for a brilliant young scientist. But was it the promise of scientific discoveries that drew Katharine to Schenectady or the need to confront the personal tragedy that marked the place where her own story began? Perhaps it was both.
Thu, 05 Feb 2026 - 41min - 142 - Layers of Brilliance: The Chemical Genius of Katharine Burr Blodgett - Episode One
In the first of this five-part season we trace Katharine’s early years as she picks up European languages, her early scientific education at a progressive New York school for girls and then Bryn Mawr, a women’s college. She seems destined to end up working at the General Electric Company’s industrial research lab, but first she must prove herself at the University of Chicago, where, in the middle of World War I, she works to improve the life-saving gas mask.
Thu, 29 Jan 2026 - 34min - 141 - Layers of Brilliance
Introducing Layers of Brilliance, a six-part season that brings to life the story of a woman whose discoveries in materials science quietly shape our everyday world – but whose legacy was long eclipsed by the famous scientist she worked with. In 1918, at just twenty years old, Katharine Burr Blodgett arrived at the General Electric Company’s industrial research laboratory in Schenectady, New York – a place known as the House of Magic. There she began a decades-long collaboration with Irving Langmuir, GE’s star scientist, who would go on to win the Nobel Prize in Chemistry. While Langmuir became a public figure, Blodgett became something else: the mind and hands behind experiments so delicate they operated at the scale of single molecules. Blodgett’s work on films just one molecule thick would lead to multiple U.S. patents and form the basis of technologies embedded in today’s screens, optics, and electronics. Listen as we peel back the layers of Katharine Burr Blodgett’s life – how she made groundbreaking science inside a world built for men, how she struggled against profound personal challenges, and how a woman whose work helped shape modern materials science nearly disappeared from history.
Thu, 15 Jan 2026 - 02min - 140 - The Lost Women of Science - Our Book for Young Readers
The Lost Women of Science by Melina Gerosa Bellows and Katie Hafner is an exciting book for young readers that brings to life the stories of ten remarkable women who changed the world of science but have been forgotten, or written out of history completely. Published by Penguin Random House’s Bright Matter imprint, the book transformspodcast episodes into a collection of inspiring biographies written for middle school readers. In this Lost Women of Science Conversation, Melina and Katie talk about their favorite female scientists and why their grit and determination can help inspire curiosity in the next generation of young female (and male) scientists. For parents, teachers or grandparents looking to spark a love of science in the young people in their lives, look no further than this book this holiday season.
Thu, 04 Dec 2025 - 21min - 139 - For Susan
In 2022, Susan Wojcicki was on top of the world—CEO of YouTube, parent to five kids, and running a few miles a day—when she received a shocking diagnosis: metastatic lung cancer. She soon resigned from YouTube and dedicated herself to fighting the disease and looking for answers. Why does the leading cause of cancer deaths receive less funding than some less lethal cancers? How could her lung cancer have progressed so far undetected? And how did Susan get lung cancer, when she had never smoked? This episode is dedicated to her.
Thu, 20 Nov 2025 - 22min - 138 - The Mouse Lady
In the 1910s, a relatively unknown cancer researcher named Maud Slye announced the first results of a study with the loftiest ambitions: to identify what causes cancer. To answer that question, the University of Chicago geneticist had bred tens of thousands of mice, enough to fill a three-story building. She carefully documented their ancestry and their morbidities and performed autopsies. And to Slye, her findings were clear: vulnerability to cancer was hereditary. If we wanted to, we could eliminate it. But Slye made some crucial mistakes along the way—and a number of enemies.
Thu, 13 Nov 2025 - 29min - 137 - Lost Women of Science Conversations: Rosalind - The Opera
Composer Peter Hugh White and librettist Clare Heath join host Rosie Millard in front of a London audience to explore why the story of chemist and x-ray crystallographer Rosalind Franklin and the race to uncover the structure of DNA makes such a compelling subject for an opera. We hear excerpts that capture the contrasting personalities at the centre of this scientific drama — James Watson, the brash young researcher at the University of Cambridge; Francis Crick, his more measured collaborator; and Maurice Wilkins, an anxious biophysicist uneasy about being outshone by his brilliant colleague, Franklin. It’s a story of ambition, rivalry, and betrayal: Franklin’s departure from King’s College London and the subsequent publication of the double helix model by Watson and Crick, which was built on insights from her work — yet without giving her due recognition.
Thu, 06 Nov 2025 - 29min - 136 - Best Of: Finding Dora Richardson: The Forgotten Developer of Tamoxifen, a Lifesaving Breast Cancer Therapy - Episode Two
Although initial clinical trials of tamoxifen as a treatment of breast cancer were positive, Imperial Chemical Industries (ICI) did not believe this market would be commercially viable. The company had hoped for a contraceptive pill – tamoxifen didn’t work for that – not a cancer treatment. In 1972 the higher-ups at ICI decided to cancel the research. But Dora Richardson, the chemist who had originally synthesized the compound, and her boss, Arthur Walpole, were convinced they were on to something important, something that could save lives. They continued the research in secret. Tamoxifen was eventually launched in 1973 and went on to become a global success, saving hundreds of thousands of lives. Dora Richardson’s role in its development, however, was overshadowed by her a male colleague and all but forgotten. This Best Of episode first aired in October 2024 to coincide with Breast Cancer Awareness month. It is now also available in a Spanish adaptation, narrated by Laura Gómez.
Thu, 16 Oct 2025 - 36min - 135 - Encontrando a Dora Richardson – La desarrolladora olvidada del tamoxifeno, una terapia vital contra el cáncer de mama
Aunque los ensayos clínicos iniciales del tamoxifeno como tratamiento del cáncer de mama fueron positivos, Imperial Chemical Industries (ICI) no creía que este mercado fuera comercialmente viable. La compañía esperaba una píldora anticonceptiva (el tamoxifeno no funcionó para eso), no un tratamiento contra el cáncer. En 1972, los superiores del ICI decidieron cancelar la investigación. Pero Dora Richardson, la química que originalmente había sintetizado el compuesto, y su jefe, Arthur Walpole, estaban convencidos de que estaban en algo importante, algo que podría salvar vidas. Continuaron la investigación en secreto. El tamoxifeno se lanzó finalmente en 1973 y se convirtió en un éxito mundial, salvando cientos de miles de vidas. El papel de Dora Richardson en su desarrollo, sin embargo, fue eclipsado por su colega masculino y casi olvidado.
Thu, 16 Oct 2025 - 33min - 134 - Best Of: Finding Dora Richardson, The Forgotten Developer of Tamoxifen, a Lifesaving Breast Cancer Therapy - Episode One
In the early 1960s, Dr. Dora Richardson synthesized a chemical compound that became one of the most important drugs to treat breast cancer: tamoxifen. Although her name is on the original patent, her contributions have been lost to history. In the first episode of this two-part podcast, Katie Couric introduces us to Dora’s story, and we show how Lost Women of Science producer Marcy Thompson tracked down Dora’s firsthand account of the history of the drug’s development. This document, lost for decades, tells the story of how the compound was made and how Imperial Chemical Industries, where Richardson worked, almost terminated the project because the company was hoping to produce a contraceptive, not a cancer therapy. This Best Of episode first aired in October 2024 to coincide with Breast Cancer Awareness month. It is now also available in a Spanish adaptation, narrated by Laura Gómez.
Thu, 09 Oct 2025 - 41min - 133 - Encontrando a Dora Richardson – Episodio 1
A principios de la década de los sesenta, la Dra. Dora Richardson sintetizó un compuesto químico que se convirtió en uno de los medicamentos más importantes para tratar el cáncer de mama: el tamoxifeno. Aunque su nombre aparece en la patente original, sus contribuciones fueron olvidadas por la historia. En el primer episodio de este podcast de dos partes, les contamos la historia de Dora y de cómo Marcy Thompson, productora de Lost Women of Science, rastreó su relato en primera persona sobre el desarrollo del medicamento. Este documento, perdido durante décadas, narra cómo se creó el compuesto y cómo la empresa Imperial Chemical Industries, donde trabajaba Richardson, estuvo a punto de cancelar el proyecto porque buscaba desarrollar un anticonceptivo, no una terapia contra el cáncer.
Thu, 09 Oct 2025 - 31min - 132 - Opening Doors to Computer Science
In high school, Carla Brodley was almost shut out of computer science when boys took over all the computers. But she rediscovered her love for the field in college and has made it her mission to open doors for others. At Northeastern University, she founded the Center for Inclusive Computing, which now partners with more than 100 institutions to make computer science more accessible. As a result of Brodley’s push to introduce more flexible degree programs, more women — and especially more women of color — have not only enrolled but stayed in the field. Now, with support from Pivotal, a group of organizations founded by Melinda French Gates, Brodley is aiming to scale up her efforts. Today she joins Lost Women of Science host Katie Hafner to share her journey, new paths to computer science, and how AI fits in.
Thu, 25 Sep 2025 - 34min - 131 - Frances Glessner Lee: The Mother of Forensic Science
Frances Glessner Lee discovered her true calling later in life. An heiress without formal schooling, she was in her fifties when she transformed her fascination with true crime and medicine into the foundation of a new field: forensic science. In the late 1920s, she drew inspiration from a family friend, a medical examiner involved in notorious cases— including the infamous Sacco and Vanzetti trial. For Glessner Lee, the puzzle of untangling the truth about violent deaths proved irresistible. She recognized that solving crimes demanded both rigorous methods and professional training. She funded and helpedfound the Department of Legal Medicine at Harvard University. Her most unusual teaching tool: intricately crafted dollhouse dioramas depicting grisly crime scenes.
Thu, 11 Sep 2025 - 38min - 130 - The Mothers of Gynecology
In this episode, Katie Hafner joins Alexis Pedrick and Mariel Carr to bring you The Mothers of Gynecology, part of Innate: How Science Invented the Myth of Race, a podcast and magazine project produced by the Science History Institute that explores the historical roots and persistent legacies of racism in American science and medicine. Of all wealthy countries, the United States is the most dangerous place to have a baby. The maternal mortality rate is abysmal, and it's getting worse. And there are huge racial disparities: Black women are three times more likely to die in childbirth than white women. Despite some claims to the contrary, the problem isn’t race, it’s racism. This episode, which first aired in April, 2023, explores the racial disparities in maternal health in the US rooted in 19th century medical exploitation of enslaved women.
Thu, 28 Aug 2025 - 1h 07min - 129 - Best Of: Dr. Sarah Loguen Fraser, an Ex-Slave’s Daughter, Becomes a Celebrated Doctor
Born in 1850, Sarah Loguen found her calling as a child, when she helped her parents and Harriet Tubman bandage the leg of an injured person escaping slavery. When the Civil War ended and Reconstruction opened up opportunities for African Americans, Loguen became one of the first Black women to earn a medical license. But quickly, racist Jim Crow laws prevailed. At the urging of family friend Frederick Douglass, Loguen married and, with her new husband, set sail for the Dominican Republic where more was possible for a person of color. This is her story. This Best Of episode, which first aired in September 2023, is also available in a Spanish adaptation, narrated by Laura Gómez.
Thu, 14 Aug 2025 - 31min - 128 - La Dra. Sarah Loguen Fraser, hija de un ex esclavo, se convierte en una destacada médica
Nacida en 1850, Sarah Loguen encontró su vocación cuando era niña, cuando ayudó a sus padres y a Harriet Tubman a vendar la pierna de una persona herida que escapaba de la esclavitud. Cuando terminó la Guerra Civil y la Reconstrucción abrió oportunidades para los afroamericanos, Loguen se convirtió en una de las primeras mujeres negras en obtener una licencia médica. Pero rápidamente, prevalecieron las leyes racistas de Jim Crow. A instancias de un amigo de la familia, Frederick Douglass, Loguen se casó y, con su nuevo esposo, se embarcó hacia la República Dominicana, donde era posible más para una persona de color. Esta es su historia.
Thu, 14 Aug 2025 - 37min - 127 - Mujeres perdidas del Proyecto Manhattan: Carolyn Beatrice Parker
Carolyn Beatrice Parker provenía de una familia de médicos y académicos y trabajó durante la Segunda Guerra Mundial como física en el Proyecto Dayton, una parte fundamental del Proyecto Manhattan encargada de producir polonio. El polonio es un metal radiactivo que se utilizó en la producción de las primeras armas nucleares. Después de la guerra, Parker continuó su investigación y sus estudios en el Instituto Tecnológico de Massachusetts, pero murió de leucemia a los 48 años antes de que pudiera defender su tesis doctoral. Décadas más tarde, durante el apogeo de las protestas de Black Lives Matter, los ciudadanos de su ciudad natal de Gainesville, Florida, votaron para cambiar el nombre de una escuela primaria en su honor.
Thu, 31 Jul 2025 - 15min - 126 - Best Of: Lost Women of the Manhattan Project - Carolyn Beatrice Parker
Carolyn Beatrice Parker came from a family of doctors and academics and worked during World War II as a physicist on the Dayton Project, a critical part of the Manhattan Project tasked with producing polonium. Polonium is a radioactive metal that was used in the production of early nuclear weapons. After the war, Parker continued her research and her studies at the Massachusetts Institute of Technology, but she died of leukemia at age 48, before she was able to defend her PhD thesis. Decades later, during the height of the Black Lives Matter protests, citizens in her hometown of Gainesville, Florida voted to rename an elementary school in her honor. This Best Of episode, which first aired in November 2024, is also available in a Spanish adaptation, narrated by Laura Gómez.
Thu, 31 Jul 2025 - 15min - 125 - Emma Unson Rotor: la física filipina que desarrolló un arma ultrasecreta
Emma Unson Rotor se tomó un permiso de su trabajo como profesora de matemáticas en Filipinas para estudiar física en la Universidad Johns Hopkins en 1941. Sus planes se vieron interrumpidos cuando el Ejército Imperial Japonés invadió y ocupó Filipinas. Incapaz de acceder a la beca que le había brindado el gobierno filipino para asistir a Johns Hopkins, se unió a la División de Desarrollo de Artillería del Buró Nacional de Estándares. Fue allí donde realizó investigaciones pioneras sobre la espoleta de proximidad, considerada “la primera arma ‘inteligente’ del mundo”, en palabras del físico Frank Belknap Baldwin, quien también colaboró en el desarrollo de dicha tecnología.
Thu, 17 Jul 2025 - 21min - 124 - Best Of: Emma Unson Rotor: The Filipina Physicist Who Developed a Top Secret Weapon
Emma Unson Rotor took leave from her job as a math teacher in the Philippines to study physics at Johns Hopkins University in 1941. Her plans were disrupted when the Imperial Japanese Army invaded and occupied the Philippines. Unable to access her Philippine government scholarship to attend Johns Hopkins, she joined the Ordnance Development Division at the National Bureau of Standards. It was here that she did groundbreaking research on the proximity fuze, the “world’s first ‘smart’ weapon,” in the words of physicist Frank Belknap Baldwin, who also helped develop the technology. This Best Of episode, which first aired in December 2923, is also available in a Spanish adaptation, narrated by Laura Gómez.
Thu, 17 Jul 2025 - 20min - 123 - Best Of: The Victorian Woman Who Chased Eclipses
The year is 1897 and Annie Maunder, an amateur astronomer, is boarding a steamship bound for India from England. Her goal: to photograph a total solar eclipse. Maunder was fascinated by the secrets of the sun and was determined to travel the globe and unlock them. She understood that the few minutes of darkness during a solar eclipse presented a special opportunity to explore the nature of the sun. Her observations led to our greater understanding of how the sun affects the earth, but like so many early female scientists, her contributions and achievements have been forgotten. This Best Of episode, which first aired in April 2024, is also available in a Spanish adaptation, narrated by Laura Gómez.
Thu, 03 Jul 2025 - 30min - 122 - La mujer victoriana que perseguía los eclipses
Corre el año 1897 y Annie Maunder, una astrónoma aficionada, aborda un barco de vapor con destino a la India desde Inglaterra. Su objetivo: fotografiar un eclipse total de sol. Maunder estaba fascinado por los secretos del sol y estaba decidido a viajar por el mundo y descubrirlos. Comprendió que los pocos minutos de oscuridad durante un eclipse solar presentaban una oportunidad especial para explorar la naturaleza del sol. Sus observaciones condujeron a una mayor comprensión de cómo el sol afecta a la Tierra, pero al igual que muchas de las primeras científicas, sus contribuciones y logros han sido olvidados.
Thu, 03 Jul 2025 - 21min - 121 - Lost Women of Science - Mujeres Olvidadas de la Ciencia - En Espanõl
Esto es Lost Women of Science - Mujeres Olvidadas de la Ciencia. Laura Gómez, conocida por su papel de Blanca Flores en la exitosa serie de Netflix “Orange Is the New Black”, es el narradora del podcast Lost Women of Science en el que contamos las historias de destacadas científicas cuyo trabajo cambió nuestro mundo, pero cuyos nombres fueron prácticamente olvidados y casi borrados de la historia. La semana que viene estrenamos una nueva temporada en español, en la que contaremos la historia de una mujer victoriana que viajó por todo el mundo para perseguir eclipses, de una científica forense que descifró misterios para la policía,de la descubridora de uno de los medicamentos que más vidas ha salvado en este planeta... ¡entre otras!
Thu, 26 Jun 2025 - 02min - 120 - Lost Women of Science - In Spanish!
After the success of our bilingual season about the first female doctor trained in the Dominican Republic, The Extraordinary Life and Tragic Death of Evangelina Rodríguez Perozo, we are adapting more of our episodes in Spanish. Starting next week, listen out for the stories of astronomer Annie Maunder, physicists Emma Unson Rotor and Carolyn Parker, and chemist and forensic scientist Mary Louisa Willard in Spanish and English. As we always say, for every Marie Curie or Rosalind Franklin whose story has been told, hundreds of female scientists remain unknown to the public at large. So, we illuminate the lives and work of a diverse array of groundbreaking scientists who, because of time, place and gender, have gone largely unrecognized. And now these stories are available in Spanish too.
Thu, 26 Jun 2025 - 01min - 119 - The Weather Expert Who Answered the $64,000 Question
In the mid-1940s, a teenage June Bacon-Bercey saw the image of a nuclear explosion on the cover of Time magazine and immediately had questions. How would the particles in the mushroom cloud move through the air? What effect would this have on our atmosphere? To find the answers, she set out to study atmospheric science, just as the field of meteorology was coming of age. Her career would take her to places few Black women had gone before: the Atomic Energy Commission as a senior researcher; a TV news station in Buffalo, New York, as an on-air meteorologist; and even a TV game show. As a Black woman entering a STEM career at the height of the Civil Rights movement, June’s goal was always to be a role model for women and people of color. And she marched through life to the tune of her favourite composer, John Philip Sousa, who just happened to help her answer the $64,000 question.
Thu, 19 Jun 2025 - 34min - 118 - Florence Nightingale and her Geeks Declare War on Death
In this episode from the Cautionary Tales podcast, Harford teams up with actor Helena Bonham Carter, a distant relative of Florence Nightingale, to tell the story of how the ‘“Lady with the Lamp” revolutionized public health with a pie chart. Nightingale was a statistician as well as a nurse, and it was her use of data graphics that led hospitals to introduce hygiene measures that we now take for granted. Her charts convinced the establishment that deaths due to filth and poor sanitation could be averted, saving countless lives. But did Nightingale also open Pandora’s Box by showing that graphs persuade, whether or not they depict reality?
Thu, 05 Jun 2025 - 46min - 117 - Lost Women of Science Conversations: Air-borneAir-Borne: the Hidden History of the Air We Breathe by Carl Zimmer charts the history of the field of aerobiology: the science dealing with airborne microorganisms. In this episode, we discover the story of two lost pioneers of the 1930s, physician and self-taught epidemiologist Mildred Weeks Wells and her husband sanitary engineer William Firth Wells, who proved that infectious diseases could be spread long distances through the air. But the pair had a reputation as outsiders and they failed to convince the scientific establishment, who ignored their findings for decades. What the pair figured out could have saved many lives from tuberculosis, SARS, COVID, and other airborne diseases. Mildred and her husband’s contributions have been all but erased from history — until now.Thu, 22 May 2025 - 33min
- 116 - Buried History: The Feminist Birth of the Home Pregnancy Test
Today, we take it for granted that you can buy a home pregnancy test at the pharmacy. Before the end of the 1970s, this was not the case. Then along came Margaret Crane, a young designer working for a pharmaceutical company. Looking at the rows of pregnancy tests in the lab one day in 1965, she thought, “Well, women could do that at home!” But Crane faced an uphill battle to convince the pharmaceutical companies, the medical community, and conservative social leaders that at-home pregnancy testing was safe and necessary. This podcast first aired in 2014, when Margaret Crane’s role in the development of the home pregnancy test was eventually recognized. Almost 10 years later, Crane’s experience remains relevant as women continue to fight for their reproductive rights. Making Contact is a radio show and podcast from Frequencies of Change Media. For a full list of the episode credits, go to: Buried History: The Feminist Birth of the Home Pregnancy Test.
Thu, 08 May 2025 - 30min - 115 - Lost Women of Science Conversations: The Elements of Marie Curie
In The Elements of Marie Curie: How the Glow of Radium Lit a Path for Women in Science Dava Sobel celebrates the many women who came to Paris to work with Marie Curie after she won the 1903 Nobel Prize in Physics. Many of these women went on to become experts in radioactivity, creating their own networks to support female scientists. Among others, we meet Norwegian Ellen Gleditsch, who was the first person to introduce the science of radioactivity to Norway and Canadian Harriet Brooks, who eventually gave up her stellar scientific career to marry. In retelling the story of Marie Curie, Sobel also shows how the women she mentored contributed to completing the periodic table in the early 20th century.
Thu, 24 Apr 2025 - 28min - 114 - In Evangelina's Footsteps | 5
After Evangelina Rodríguez Perozo died in 1947, the Trujillo regime did its best to erase her legacy, while at the same time appropriating her ideas. Yet those who had known and loved Evangelina in San Pedro de Macorís, where she spent most of her life, kept her memory alive, sharing stories of her kindness and her work. After the assassination of Rafael Leónidas Trujillo in 1961, Dominicans across the country started to recover her story. Laura Gómez follows in Evangelina’s footsteps across Santo Domingo, the city where Evangelina studied medicine, and visits the memorials that are testament to Evangelina’s role in the fight for women's health and reproductive rights, a struggle that continues in the Dominican Republic to this day.
Thu, 10 Apr 2025 - 21min - 113 - Siguiendo los pasos de Evangelina | 5
Tras la muerte de Evangelina Rodríguez Perozo en 1947, el régimen de Trujillo hizo todo lo posible no solo por borrar su legado, sino también por apropiarse de sus ideas. Sin embargo, quienes conocieron y quisieron a Evangelina en San Pedro de Macorís mantuvieron su memoria viva, compartiendo historias sobre su bondad y su trabajo. Tras el asesinato de Rafael Leónidas Trujillo en 1961, los dominicanos de todo el país empezaron a recuperar su historia. Laura Gómez sigue los pasos de Evangelina por Santo Domingo, la ciudad donde estudió medicina, y visita los monumentos que son testigo de su papel en la lucha por la salud y los derechos reproductivos de las mujeres, una lucha que continúa en los derechos reproductivos hasta el día de hoy.
Thu, 10 Apr 2025 - 23min - 112 - El dictador y la doctora | 4
En 1930, Rafael Leónidas Trujillo toma el poder en la República Dominicana e instaura un reino de terror. El controvertido trabajo de Evangelina la puso en conflicto con el nuevo régimen. Sus ideas radicales sobre la sanidad y los derechos de la mujer, junto con su negativa a doblegarse ante Trujillo, la dejaron cada vez más aislada. Cada vez más gente se distanciaba de ella. Con los años, su salud mental se deterioró y perdió todo lo que apreciaba.
Thu, 03 Apr 2025 - 29min - 111 - The Dictator and the Doctor | 4
In 1930, Rafael Leónidas Trujillo seized power in the Dominican Republic and introduced a reign of terror. Evangelina’s controversial work brought her into conflict with the new regime. Her radical ideas about healthcare and women's rights, along with her refusal to kowtow to Trujillo, left her increasingly isolated. More and more people distanced themselves from her. Over the years, her mental health deteriorated, and she lost everything she held dear.
Thu, 03 Apr 2025 - 26min - 110 - El retorno de la doctora rebelde | 3
Evangelina recibió una calurosa bienvenida de regreso a su país, y se pone a trabajar de inmediato, introduciendo sus nuevas ideas sobre la atención en salud a mujeres y niños. Montó su propio consultorio médico, y convenció a algunos campesinos para que distribuyesen leche gratis a niños pobres. Pero su proselitismo alrededor de los métodos anticonceptivos y su trabajo con prostitutas incomodaron hasta a sus amigas. Sus ideas eran muy avanzadas para la época, y aquellos que la rodeaban no supieron valorarlas.
Thu, 27 Mar 2025 - 28min - 109 - The Rebel Doctor Returns | 3
Evangelina got a warm welcome on her return from Paris and went straight to work, introducing her new ideas about healthcare for women and children. She set up a new medical practice, and managed to get farmers to provide free milk for poor infants. But her proselytizing about contraception and her work with prostitutes made even her friends uncomfortable. Her ideas were ahead of her time, and those around her failed to keep up.
Thu, 27 Mar 2025 - 25min - 108 - A Dominican in Paris | 2
Devastated by the death of her mentor following childbirth, Evangelina decided to devote her life to women’s health. It took a decade to raise the money to go to Paris, which was then the mecca of medical training, but she never gave up. At the age of 42 she boarded a steamship to France. Amidst the post-war scene of France's Roaring Twenties, she studied obstetrics and gynecology with leading specialists and started to absorb modern ideas about public health. Her goal: to return home and revolutionize Dominican healthcare.
Thu, 20 Mar 2025 - 29min - 107 - Una dominicana en París | 2
Devastada por la muerte de su mentora, ocurrida tras un parto, Evangelina decidió dedicar su vida a la salud de la mujer. Tardó una década en reunir el dinero para ir a París, que en ese entonces era la meca de la formación médica. Nunca se rindió. A los 42 años se embarcó en un buque de vapor rumbo a Francia, país que experimentaba un boom durante los años de la posguerra. Estudió obstetricia y ginecología con los mejores especialistas y empezó a asimilar las ideas modernas sobre salud pública. Su objetivo: volver a su país y revolucionar la sanidad dominicana.
Thu, 20 Mar 2025 - 32min - 106 - La doctora | 1
A finales de la década de 1890, Andrea Evangelina Rodríguez Perozo era una de las tantas niñas pobres luchando por sobrevivir en la ciudad de San Pedro de Macorís, en la República Dominicana. Su vida dio un giro extraordinario cuando dos hermanos, poetas y escritores, llegaron de la capital. Notaron algo especial en la joven, quien vivía cerca. Con su ayuda, Evangelina fue a la escuela y, contra todo pronóstico, decidió ser médica. Fue la primera mujer en estudiar en una escuela de medicina en la República Dominicana y, cuando se graduó en 1911, se convirtió en la primera doctora del país. Pero justo cuando estaba a punto de empezar su carrera, una tragedia inesperada cambiaría el curso de su vida.
Thu, 13 Mar 2025 - 27min - 105 - La Doctora | 1
In the late 1890s, Andrea Evangelina Rodríguez Perozo, known as Evangelina, was just another poor girl trying to survive in the provincial town of San Pedro de Macorís in the Dominican Republic. Her life took an extraordinary turn when two brothers, both poets and writers, arrived from the capital. They noticed something special about the young girl who lived nearby. With their help, Evangelina went to school and, against overwhelming odds, decided to become a doctor. She was the first woman to enter medical school in the Dominican Republic, and when she graduated in 1911 she became the country's first female doctor. But just as she was about to start her career an unexpected tragedy changed the course of her life.
Thu, 13 Mar 2025 - 24min - 104 - La Extraordinaria Vida y Trágica Muerte de Evangelina Rodríguez Perozo
En la década de 1880, una pequeña niña Afro-Dominicana pasaba sus días vendiendo dulces en las calles de San Pedro de Macorís, una bulliciosa ciudad portuaria en la República Dominicana. Abandonada por sus padres, quienes la tuvieron por fuera del matrimonio, su futuro parecía gris: en esta sociedad profundamente estratificada, pocas personas lograban escapar de la vida en la que habían nacido. Pero Andrea Evangelina Rodríguez Perozo tenía algo que hacía que los demás se fijaran en ella. Así ocurrió con dos hermanos influyentes, ambos poetas e intelectuales, quienes reconocieron en ella una mente brillante y un espíritu tenaz. Con el apoyo de ellos, Evangelina logró hacerse un camino inimaginable: convertirse en la primera mujer médica de su país. En esta temporada de cinco capítulos seguiremos a Evangelina mientras estudia medicina, primero en su país natal y luego en París, donde aprende nuevas técnicas en el campo emergente de la ginecología y se encuentra con ideas radicales sobre la salud de las mujeres, ideas que espera transformen la sociedad de su país natal. Poco imaginaba que sus nuevos enfoques sobre la salud femenina eventualmente la llevarían a su trágica caída. Las contribuciones de Evangelina Rodríguez como reformadora y pionera de la salud pública serían prácticamente borradas por el dictador cuyo régimen la persigue hasta su muerte. Aquí reconstruimos su vida y su legado.
Thu, 06 Mar 2025 - 01min - 103 - The Extraordinary Life and Tragic Death of Evangelina Rodríguez Perozo
In the 1880s, a small Afro-Dominican girl spent her days selling sweets on the streets of San Pedro de Macorís, a bustling port town in the Dominican Republic. Born out of wedlock and abandoned by her parents, her horizons seemed narrow — in this deeply stratified society, few people ever broke free from the life they were born into. But Andrea Evangelina Rodríguez Perozo had something that made people take notice. Two influential brothers, both poets and intellectuals, recognized a brilliant mind and a tenacious spirit. With the brothers’ support, Evangelina went on to chart a path that was unheard of for any Dominican woman at that time: she became her country’s first female doctor. In this five-part season, we will follow Evangelina as she studies medicine, first in her home country, then in Paris, where she learns new medical techniques in the emerging field of gynecology and encounters radical ideas about women’s health: ideas that she hopes will transform her society back in the Dominican Republic. Little does she think her new approaches to women’s health will eventually lead to her tragic downfall. Evangelina Rodríguez’s contributions as a reformer and pioneer in public health were all but erased by the dictator whose regime hounds her to death. Here, we piece together her life and her legacy.
Thu, 06 Mar 2025 - 01min - 102 - Lost Women of Science Conversations: Lady Tan's Circle of Women
Lisa See’s novel Lady Tan’s Circle of Women is inspired by a medical textbook published in 1511 by an eminent female doctor, Tan Yunxian. In this episode, we talk to See about the origin of her novel, and to Lorraine Wilcox, the scholar who translated the original Chinese text, about what the practice of medicine was like for a female doctor during the Ming Dynasty. Tan Yunxian was almost lost to history, but the chronicle of her cases was reprinted by a great nephew and, amazingly, one copy survived through the centuries. Through serendipitous scholarly connections, Wilcox translated it and See used that translation as the inspiration for her novel.
Thu, 27 Feb 2025 - 34min - 101 - Who Discovered the Cause of Down Syndrome ? Episode Two
In 1960 Marthe Gautier left the lab where she had discovered the genetic cause of Down syndrome, and went on to have a successful career as a pediatric cardiologist. For decades, she remained silent as her former colleague Jérôme Lejeune continued to take credit for this pioneering discovery, and history wrote her out of the story. Until 2009. On the 50th anniversary of the paper that announced the discovery of trisomy 21, she decided to set the record straight. The process of changing history did not always go smoothly. In 2014, at the age of 88, she was set to give a talk and receive a medal at a conference, but the event was canceled hours in advance, and she was given the medal privately the next day. Finally, toward the end of her life, Gautier got the recognition she deserved. Before she died in 2022, she was also decorated by the French government for her contributions to science.
Thu, 13 Feb 2025 - 31min - 100 - Who Discovered the Cause of Down Syndrome? Episode One
In the mid-1950s Marthe Gautier, a young French doctor and cytogenetics researcher, led a cutting-edge experiment to investigate the cause of Down syndrome. She painstakingly cultured cells in a ramshackle lab until one day she discovered an extra chromosome in the cells of patients with Down syndrome. This proved beyond a doubt that Down syndrome is genetic. In this first episode of our two-part series about Gautier, she sees her discovery appropriated by a male colleague as he rushes to publish her findings. Jérôme Lejeune is listed as the lead author of the discovery even though Gautier did the work. Her name is listed second on this groundbreaking paper, published in 1959. And to add insult to injury, it is misspelled. It will take decades for Gautier to speak out.
Thu, 06 Feb 2025 - 25min - 99 - Margarethe Hilferding, Sigmund Freud, and the Conspiracy of Silence
In honor of International Holocaust Remembrance Day, we are telling the story of Margarethe Hilferding, a pioneering psychoanalyst and physician from Vienna who was murdered in a Nazi concentration camp in 1942. She was the first woman to earn a medical degree at the University of Vienna and the first woman to join Sigmund Freud’s Vienna Psychoanalytic Society. In her paper On the Basis of Mother Love, presented to the society in 1911, she argued that the maternal instinct is not innate but can develop after birth, a theory Freud and the rest of her male colleagues rejected. Margarethe soon left the society and devoted much of her life to treating women in working class neighborhoods and advocating for their reproductive health. Her theory of maternal instinct remains controversial even today.
Thu, 23 Jan 2025 - 41min - 98 - Lost Women of Science Conversations: Breaking Through
Dr. Katalin Karikó, a Hungarian-born biochemist, dedicated her life’s work to messenger RNA, which she always believed had the potential to change the world. After decades of being ignored, she persisted with the research that eventually revolutionized the field of medicine and enabled the development of lifesaving vaccines in record time during the COVID-19 pandemic. Dr. Karikó tells her story in her memoir, Breaking Through: My Life In Science, sharing her journey from young researcher in Hungary to Nobel Prize-winning biochemist. In this conversation, she reflects on the challenges and breakthroughs that defined her career, her resilience, and the scientific curiosity that fueled her passion for mRNA research
Thu, 09 Jan 2025 - 34min - 97 - Best Of: Flora Patterson, the Woman who Kept Devastating Blights from U.S. Shores
At this festive time of year, when many people are bringing trees into their homes to decorate for the holidays, we are going back to our story of a pioneering scientist who made it her mission to ensure that plants traveling across borders did not carry any diseases. It was in 1909, that the Mayor of Tokyo sent a gift of 2,000 prized cherry trees to Washington, D.C. But the iconic blossoms enjoyed each spring along the Tidal Basin are not from those trees. That’s because Flora Patterson, who was the Mycologist in Charge at the USDA, recognized the original saplings were infected, and the shipment was burned on the National Mall. In this episode, we explore Patterson’s lasting impact on the field of mycology, starting with a blight that killed off the American chestnut trees, and how she helped make the USDA’s National Fungus Collection the largest in the world.
Thu, 19 Dec 2024 - 26min - 96 - Lost Women of Science Conversations - Brave the Wild River
Two female botanists – Elzada Clover and Lois Jotter – made headlines for riding the rapids of the Colorado River in 1938 in an effort to document the Grand Canyon’s plant life. In Brave the Wild River: The Untold Story of Two Women Who Mapped the Botany of the Grand Canyon, author Melissa L. Sevigny retraces their journey and shows how the ambitious river expedition, one that many believed impossible for women, changed not only Clover and Jotter but also our understanding of botany in this remote corner of the American West.
Thu, 05 Dec 2024 - 30min - 95 - Lost Women of the Manhattan Project: Carolyn Beatrice Parker
Carolyn Beatrice Parker came from a family of doctors and academics and worked during World War II as a physicist on the Dayton Project, a critical part of the Manhattan Project tasked with producing polonium. (Polonium is a radioactive metal that was used in the production of early nuclear weapons.) After the war, Parker continued her research and her studies at the Massachusetts Institute of Technology, but she died of leukemia at age 48 before she was able to defend her PhD thesis. Decades later, during the height of the Black Lives Matter protests, citizens in her hometown of Gainesville, Florida voted to rename an elementary school in her honor. November 18th would have been her 107th birthday.
Thu, 21 Nov 2024 - 15min - 94 - Lost Women of Science Conversations: Attention is Discovery
Anna Von Mertens' thoughtful new exploration of Henrietta Swan Leavitt's life describes and illuminates Leavitt's decades-long study of stars, including the groundbreaking system she developed for measuring vast distances within our universe simply by looking at photographic plates. Leavitt studied hundreds of thousands of stars captured on the glass plates at the Harvard College Observatory, where she worked as a human computer from the turn of the 20th century until her death in 1921. Von Mertens explores her life, the women she worked alongside, and her discoveries, weaving biography, science, and visual imagery into a rich tapestry that deepens our understanding of the universe and the power of focused, methodical attention.
Thu, 14 Nov 2024 - 28min - 93 - Finding Dora Richardson: The Forgotten Developer of Tamoxifen, a Lifesaving Breast Cancer Therapy - Episode Two
Although initial clinical trials of tamoxifen as a treatment of breast cancer were positive, Imperial Chemical Industries (ICI) did not believe this market would be commercially viable. The company had hoped for a contraceptive pill – tamoxifen didn’t work for that – not a cancer treatment. In 1972 the higher-ups at ICI decided to cancel the research. But Dora Richardson, the chemist who had originally synthesized the compound, and her boss, Arthur Walpole, were convinced they were on to something important, something that could save lives. They continued the research in secret. Tamoxifen was eventually launched in the U.K. in 1973 and went on to become a global success, saving hundreds of thousands of lives. Dora Richardson’s role in its development, however, was overshadowed by her a male colleague and all but forgotten.
Thu, 31 Oct 2024 - 36min - 92 - Finding Dora Richardson - The Forgotten Developer of Tamoxifen
In the early 1960s, chemist Dr. Dora Richardson synthesized a chemical compound that became one of the most important drugs to treat breast cancer: tamoxifen. Although her name is on the original patent, her contributions have been lost to history. In the first episode of this two-part podcast, Katie Couric introduces us to Dora’s story. Lost Women of Science producer Marcy Thompson tracked down Dora’s firsthand account of the history of the drug’s development. This document, lost for decades, tells the story of how the compound was made and how Imperial Chemical Industries, where Richardson worked, almost terminated the project because the company was hoping to produce a contraceptive, not a cancer therapy.
Thu, 24 Oct 2024 - 41min - 91 - Lost Women of Science Conversations: Wonder Drug
While researching her book about thalidomide in America, Jennifer Vanderbes discovered that there were far more survivors in the U.S. than originally thought – at least ten times more. These survivors were born with shortened limbs and other serious medical conditions after their mothers unwittingly took thalidomide in the early 1960s in so-called clinical trials. Wonder Drug tells the story of Vanderbes’ trek across the U.S. in search of these thalidomide survivors. It also revisits the role of the U.S. Food and Drug Administration medical reviewer Dr. Frances Oldham Kelsey – the subject of our recent five-part season – who refused to approve thalidomide for sale in the U.S. In the process of writing her book, Vanderbes became an advocate for the survivors, now in their sixties, and their search for justice and support.
Thu, 17 Oct 2024 - 36min - 90 - The Devil in the Details - Chapter Five
It’s September 2024 and a group of American thalidomide survivors arrive in Washington D.C. to lobby the government for support. More than 60 years have gone by since Frances Kelsey first stalled the New Drug Approval application from pharma company Merrell for thalidomide. Although she stopped the drug from going on the market in the U.S., hundreds of pregnant women still took thalidomide in Merrell’s so-called clinical trials, and many had babies with shortened limbs and serious medical conditions. Others had miscarriages or stillborn babies. Here we look at the legacy of thalidomide, the changes in drug regulations in the wake of the scandal, and what happened to our hero, Frances Kelsey.
Thu, 10 Oct 2024 - 36min - 89 - The Devil in the Details - Chapter Four
It’s the summer of 1962 and thalidomide has been off the market in Europe for months. But in the U.S., people are only just beginning to find out about the scandal. The Washington Post breaks the story and puts a picture of Frances Kelsey on the front page. She’s the hero who saved American lives. President John F. Kennedy gives her a medal and her image is splashed across newspapers around the country. At the end of the previous year, Merrell, the company that wanted to sell thalidomide in the U.S., had made a half-hearted attempt to contact some of the doctors who had been given millions of thalidomide samples for so-called clinical trials. Just how many pregnant women might have thalidomide in their medicine cabinets?
Thu, 03 Oct 2024 - 33min - 88 - The Devil in the Details - Chapter Three
It’s 1961 and Widukind Lenz, a German pediatrician, is going door to door in his efforts to find out what is causing the epidemic of babies born with shortened limbs and other serious medical conditions. In the U.S., drug company Merrell is battling with Dr. Frances Kelsey at the Food and Drug Administration about the approval for thalidomide. She’s asking for data that shows it’s safe in pregnancy (spoiler alert: it’s not). Meanwhile, Merrell continues to send hundreds of thousands of thalidomide pills to doctors in so-called clinical trials. In November 1961, Dr. Lenz goes public with the results of his medical sleuthing and, as host Katie Hafner puts it, “the proverbial shit hits the proverbial fan.”
Thu, 26 Sep 2024 - 28min - 87 - The Devil in the Details - Chapter Two
It’s the early 1960s and the German pharmaceutical market is booming. A sedative called Contergan is one of the bestselling drugs. Contergan’s active ingredient is thalidomide and it is touted as a wonder drug, a non-addictive sedative safer than barbiturates. In the U.S., the drug is called Kevadon, and its distributor is impatient to get the drug on the market. But Dr. Frances Kelsey, a medical examiner at the U.S. Food and Drug Administration, is stalling the approval of Kevadon. She wants more information from the manufacturer to prove it is safe. Meanwhile, doctors in Scotland and Australia are beginning to suspect thalidomide might, in fact, be very toxic. And in Germany, reports are beginning to emerge of a mysterious epidemic of babies born with missing limbs and other serious medical conditions, but doctors have no idea what's causing it.
Thu, 19 Sep 2024 - 30min - 86 - The Devil in the Details - Chapter One
In this first chapter of a new five-part season we meet Dr. Frances Oldham Kelsey, a physician and pharmacologist who joined the U.S. Food and Drug Administration as a medical reviewer in 1960. Before the year is out, Dr. Kelsey finds herself standing up to big pharma. It’s September 1960 and a thick New Drug Application lands on Dr. Kelsey’s desk. The drug has already been on the market in Europe for three years and Dr. Kelsey’s supervisors expect her to rubber stamp the application. The drug is called Kevadon. Active ingredient: thalidomide. And to Frances Kelsey’s keen eye, something looks off.
Thu, 12 Sep 2024 - 29min - 85 - Trailer: The Devil in the Details
In the 1950s, a German drug company developed a new sedative that was supposed to be 100% safe: thalidomide. So safe, in fact, it was promoted to women as a treatment for morning sickness. It quickly became a bestseller. But in the early 1960s, shocking news started coming out of Europe. Thousands of babies were being born with shortened arms and legs, heart defects, and other serious problems. Many died. In the United States things were different, thanks to one principled, strong-minded skeptic who joined the Federal Drug Administration in 1960 as a medical reviewer. One of her first assignments was to review the approval application of that very wonder drug, thalidomide. But the application was, to her mind, flawed. Dr. Frances Oldham Kelsey was a physician, a pharmacologist, and a nitpicker who refused to be intimidated by big pharma. Starting in September, a new five-part series from Lost Women of Science: The Devil in the Details, the story of Frances Oldham Kelsey, The Doctor Who Said No To Thalidomide.
Thu, 29 Aug 2024 - 01min - 84 - Lost Women of Science Conversations: Writing for Their Lives
In the 1920s, when newspapers and magazines started to showcase stories about science, many of the early science journalists were women, working alongside their male colleagues despite less pay and outright misogyny. They were often single or divorced and, as Marcel Chotkowski LaFollette explains, writing for their lives. From Emma Reh, who traveled to Mexico to get a divorce and ended up trekking to archeological digs on horseback, to Jane Stafford, who took on taboo topics like sex and sexually transmitted diseases, they started a tradition of explaining science to non-scientists, accurately and with flair.
Thu, 22 Aug 2024 - 28min - 83 - The Quest for Everything
By the second half of the 20th century, physicists were on a mission to find the ultimate building blocks of the universe. What you get when you zoom in all the way to the tiniest bits that can’t be broken down anymore. They had a kind of treasure map, a theory describing these building blocks and where we might find them. But to actually find them, physicists needed to recreate the blistering-hot conditions of the early universe, when many of these particles last existed. That’s why, in the mid-1970s, a major national laboratory entrusted Helen Edwards with a huge task: to oversee the design and construction of the most powerful particle accelerator in the world, the first of a new generation of particle colliders built to uncover the inner workings of the universe.
Thu, 08 Aug 2024 - 29min - 82 - Dr. Jess Wade, Physicist and Wikipedia MavenDr. Jess Wade is a physicist at Imperial College London who’s made it her mission to write and update the Wikipedia pages of as many women in STEM as she possibly can. She inspired us at Lost Women of Science to start our own Wikipedia projectto ensure that all the female scientists we profile have accurate and complete Wikipedia pages. In this episode, Jess talks with us about what she does and why she does it.Thu, 25 Jul 2024 - 15min
- 81 - Lost Women of Science Conversations: The Exceptions
Dr. Nancy Hopkins, a molecular biologist who made major discoveries in cancer genetics, became an unlikely activist in her early fifties. She had always believed that if you did great science, you would get the recognition you deserved. But after years of humiliations — being snubbed for promotions and realizing the women's labs were smaller than those of their male counterparts — she finally woke up to the fact that her beloved MIT did not value women scientists. So measuring tape in hand, she collected the data to prove her point. In The Exceptions: Nancy Hopkins, MIT, and the Fight for Women in Science, Kate Zernike tells Nancy's story, which led to MIT’s historic admission of discriminationagainst its female scientists in 1999. Host Julianna LeMieux talks with Kate and Nancy about the journey.
Thu, 11 Jul 2024 - 34min - 80 - Chemistry Professor and Crime Buster: The Remarkable Life of Mary Louisa Willard
“The only time I ever saw something that I thought was abnormal…there was a human arm in the refrigerator,” said J. Peter Willard about his aunt, Mary Louisa Willard. Otherwise, he insisted, she was just “very normal.” But Mary Louisa Willard, a chemistry professor at Pennsylvania State University in the late 1920s, left a strong impression on most people, to say the least. Her hometown of State College, Pennsylvania, knew her for stopping traffic in her pink Cadillac to chat with friends and for throwing birthday bashes for her beloved cocker spaniels. Police around the world knew her for her side hustle: using chemistryto help solve crimes.
Thu, 27 Jun 2024 - 30min - 79 - Lost Women of Science Conversations: Wild By Design
When Laura J. Martin decided to write a history of ecological restoration, she didn’t think she would have to go back further than the 1980s to uncover its beginnings. What she found, however, deep in the archives, was evidence of a network of early female botanists from the turn of the last century who had been written out of history. Wild by Design: The Rise of Ecological Restoration sets the record straight. It tells the stories of Eloise Butler, Edith Roberts and the wild and wonderful gardens they planted and studied.
Thu, 13 Jun 2024 - 26min - 78 - Revisiting The Pathologist in the Basement: Episode 4 Breakfast in the Snow
In our final episode, we explore Dorothy Andersen’s legacy — what she left behind and how her work has lived on since her death. Describing her mentor’s influence on her life and career, Dr. Celia Ores gives us a rare look at what Dr. Andersen was really like. We then turn to researchers, physicians, and patients, who fill us in on the many areas of progress that have grown out of Dr. Andersen’s work. These major developments include the discovery of the cystic fibrosis gene, the tremendous impact of the drug Trikafta, and the lifesaving potential of gene editing techniques. We end the episode with an update on the effect Trikafta has had on the lives of many CF patients, who can now expect to live a normal life.
Thu, 30 May 2024 - 42min - 77 - Revisiting the Pathologist in the Basement: Episode 3 The Case of the Missing Portrait
The missing portrait of Dr. Andersen takes us on a journey into the perils of memorialization and who gets to be remembered. Dr. John Scott Baird, Dorothy Andersen’s biographer, looks for the portrait, and Drs. Nientara Anderson and Lizzy Fitzsousa, former medical students at Yale University, explain how “dude walls” — the paintings of male scientists that line institutional walls — can have an insidious effect on those who walk past them every day. And we go back to Columbia University to give you an update on the hunt for the missing portrait.
Thu, 23 May 2024 - 29min - 76 - Revisiting the Pathologist in the Basement: Episode 2 The Matilda Effect
Our associate producer, Sophie McNulty, rummages through boxes in a Connecticut basement, looking for clues to Dorothy Andersen’s life story. Pediatric critical care physician Dr. John Scott Baird, who published a biography of Dorothy Andersen in 2021, suggests we take a second look at the conventional wisdom surrounding the evolution of cystic fibrosis research in the 1950s. And in this updated episode, we interview science historian Margaret Rossiter, who coined the term “Matilda Effect” to describe how credit for work done by female scientists too often goes to their male colleagues. We examine how this affected Dorothy Andersen and her groundbreaking research into cystic fibrosis.
Thu, 16 May 2024 - 44min - 75 - Revisiting the Pathologist in the Basement
A few important things have happened in the three years since we first aired The Pathologist in the Basement, the story of Dr. Dorothy Andersen, the first to identify cystic fibrosis. It’s safe to say that Dr. Anderson is now a little less lost. In Episode 1, Dr. Andersen sleuths her way to the discovery of cystic fibrosis, a fatal disease that affects the lungs, the pancreas, and a host of other organs. So, who was Dorothy Andersen, and how did she come to make this seminal medical contribution?
Thu, 09 May 2024 - 31min - 74 - Lost Women of Science Conversations: Mathematics for Ladies
When poet Jessy Randall started researching the lives of female scientists she became angry. And we certainly can relate here at Lost Women of Science. So many women made important discoveries but received little recognition. In this episode of Lost Women of Science Conversations, Randall talks to Carol Sutton Lewis about Mathematics for Ladies: Poems on Women in Science, the collection of poems born of that anger. They discuss what it means to be the first in a field, the ethics of poetic license, and the importance of female role models in STEM. Randall’s poems are about some of the women we’ve featured in our podcast, including the first Black female doctor, Rebecca Lee Crumpler, and the physicist Lise Meitner.
Thu, 02 May 2024 - 26min - 73 - Elizabeth Bates and the Search for the Roots of Human Language
“We were each put on earth to torment the other,” says cognitive scientist Steven Pinker of Elizabeth Bates, a psychologist who challenged the prevailing theory about how humans acquire language. Bates believed that language emerges from interactions between our brains and our environments, and that we do not have an innate language capacity. To many, that sounds like an innocuous statement. But in making these claims, Bates challenged formidable linguists like Pinker and Noam Chomsky, placing herself at the center of a heated debate that remains unresolved half a century later.
Thu, 25 Apr 2024 - 37min - 72 - The Theoretical Physicist Who Worked With J. Robert Oppenheimer at the Dawn of the Nuclear AgeMelba Phillips, who grew up on a farm in Indiana at the turn of the 20th century, was one of J. Robert Oppenheimer’s first graduate students at the University of California, Berkeley. Together they discovered the Oppenheimer-Phillips Process, which explained a particular kind of nuclear reaction. In this episode, we explain what that is, with a little help from generative AI. Phillips did not follow Oppenheimer to Los Alamos, and was vocal in her opposition to nuclear weapons. During the McCarthy era, she lost her teaching job, and did not return to academia until 1957. In 1962, then in her mid-fifties, she finally became a full professor at the University of Chicago.Thu, 18 Apr 2024 - 30min
- 71 - Best Of: The Highest of All Ceilings, Astronomer Cecilia Payne-GaposchkinCecilia Payne-Gaposchkin was in her early 20s when she figured out what the stars are made of. Both she and her groundbreaking findings were ahead of their time. Continuing the legacy of women working at the Harvard College Observatory, Cecilia charted the way for a generation of female astronomers to come. This Best Of episode of Lost Women of Science follows Cecilia’s journey of discovery, journals her drive and determination against all odds, and takes you to the Harvard College Observatoryitself to walk in Cecilia’s footsteps.Thu, 11 Apr 2024 - 29min
- 70 - The Victorian Woman Who Chased Eclipses
The year is 1897 and Annie Maunder, an amateur astronomer, is boarding a steamship bound for India from England. Her goal: to photograph a total solar eclipse. Like the many people whose gaze will turn upwards in North America on April 8, Maunder was fascinated by the secrets of the sun and was determined to travel the globe and unlock them. She understood that the few minutes of darkness during a solar eclipse presented a special opportunity to explore the nature of the sun. Her observations led to our greater understanding of how the sun affects the earth, but like so many early female scientists, her contributions and achievements have been forgotten.
Thu, 04 Apr 2024 - 30min - 69 - Lost Women of Science Conversations: Mischievous Creatures
In this episode of Lost Women of Science Conversations, Michelle Nijhuis talks to historian Catherine McNeur about how she rediscovered the lives and work of Elizabeth and Margaretta Morris, two natural scientists who made significant contributions to botany and entomology in the mid-19th Century. Elizabeth collected rare plant species and sent them to institutions around the world, and Margaretta not only discovered new insects but also helped farmers combat the pests that were devastating their fields. Nevertheless, by both design and accident, these women were lost to history. McNeur tells us how that happened and how, piece by piece, she recovered their stories.
Thu, 28 Mar 2024 - 25min - 68 - The Cognitive Scientist Who Unraveled the Mysteries of Language
While working at the Salk Institutein California, Ursula Bellugi discovered that sign language was made up of specific building blocks that were assembled following strict rules, much like in spoken language. Her subsequent discoveries about the complexities of sign language led both to linguistic breakthroughs and to changes in the way deaf people felt about signing. Bellugi demonstrated that sign language is as rich and complex as any spoken language. Her work deepened our understanding of what it means to communicate as humans.
Thu, 21 Mar 2024 - 16min - 67 - Best Of: Meet the Physicist who Spoke Out Against the Bomb She Helped Create
Katharine “Kay” Way was a nuclear physicist who worked at multiple Manhattan Project sites. She was an expert in radioactive decay. But after the atomic bombs were dropped on Japan, she became increasingly concerned about the ethics of nuclear weapons. Dr. Way signed the Szilard Petition and worked to spread awareness of the moral responsibility surrounding atomic weaponry, including co-editing the influential One World or None: a Report to the Public on the Full Meaning of the Atomic Bomb, remaining an outspoken advocate for fairness and justice.
Thu, 14 Mar 2024 - 23min - 66 - How Lilian Bland Built Herself A Plane
“Hoots and derision, which did not worry me at all,” Lilian Bland wrote, describing her visit to an airshow in Blackpool, England in 1909. She’d been telling everyone there that she intended to build and fly her own airplane. They were unimpressed. Lilian was undeterred. She built a DIY plane of bamboo, wood, and fabric, with a bicycle handlebar for steering and an engine she carried from England back to her home in Ireland. But would the Mayfly,as she called it, fly?
Thu, 07 Mar 2024 - 39min - 65 - Lost Women of Science Conversations: The Black Angels
In the first of a new series we’re calling Lost Women of Science Conversations—and a fitting choice for Black History Month—we talk to Maria Smilios, author of a new book that tells the story of Black nurses who were lured from the Jim Crow South to work at a tuberculosis (TB) hospital called Sea View on Staten Island, N.Y. Facing unsanitary conditions and racial prejudice, these “Black Angels” cared for TB patients for decades before a cure that they helped develop was found. It’s a story of bravery and dedication that Smilios pieced together from oral histories and medical records because there were no archives that described these nurses’ work.
Thu, 29 Feb 2024 - 27min - 64 - The Industrial Designer Behind the N95 Mask
Sara Little Turnbull was a force in the world of material science and industrial design. It’s safe to say most people will have used something that started life on her drawing board, but few will know her name. She worked with engineered fabrics at 3M, designing a moldable bra cup that inspired the design of the N95 mask. Later 3M disputed her role in coming up with the mask. She also worked on clear glass cooktop development, the early microwave, storage systems, and many other products.
Thu, 15 Feb 2024 - 12min - 63 - The Universe in Radio Vision
The Australian physicist Ruby Payne-Scotthelped lay the groundwork for a whole new kind of astronomy: radio astronomy. By scanning the skies for radio waves instead of the light waves we can see with our eyes, Ruby and her colleagues opened a window into the universe and transformed the way we explore it. But to keep her job as a woman working for the Australian government in the 1940s, Ruby had to keep a pretty big secret.
Thu, 08 Feb 2024 - 28min - 62 - From Our Inbox: Forgotten Electrical Engineer’s Work Paved the Way for Radar Technology
Sallie Pero Mead was first hired at AT&T in 1915 as a “computer”—a human calculator—shortly after completing her master’s degree in mathematics at Columbia University. Before long she started working on the company’s transmission engineering team as both a mathematician and an electrical engineer. She and her team developed and tested hollow metal tubes used as waveguides: structures that confine and direct electromagnetic waves. In 1933 they discovered a new way that hyperfrequency waves could propagate down these tubes, and this made radar technology possible—just in time for use in World War II.
Thu, 01 Feb 2024 - 15min - 61 - Best of: A Complicated Woman, Leona Zacharias
Scientist Leona Zacharias was a rare woman. She graduated fromBarnard College in 1927 with a degree in biology, followed by a Ph.D. fromColumbia University. But throughout her career she labored behind men with loftier titles who got the bulk of the credit. In the 1940s, when premature babies born with healthy eyes were going blind, Dr. Zacharias was part of the team that worked to root out the cause. In this best ofLost Women of Science episode, hostKatie Hafner visits the archives atM.I.T. andThe Massachusetts Eye and Ear Infirmary in Boston to try to understand Dr. Zacharias’s role in rooting out the cause. For host Katie Hafner, it's personal: Leona Zacharias was her grandmother.
Thu, 25 Jan 2024 - 37min - 60 - From Our Inbox: Vera Peters - The Doctor Who Helped Spare Women From Radical Mastectomy
Vera Peters began her career studying treatment for Hodgkin lymphoma. She used techniques that had seen positive outcomes on Hodgkin’s to treat breast cancer patients, and she discovered a treatment that was equally effective and much less invasive than the radical mastectomy, saving hundreds of thousands of women from that life-altering surgery.
Thu, 11 Jan 2024 - 12min
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