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talkBD Bipolar Disorder Podcast

talkBD Bipolar Disorder Podcast

CREST Bipolar Disorder Network

talkBD gathers top bipolar experts, psychiatrists, psychologists, and researchers from around the world to discuss and answer live questions on a topic area important to life with bipolar disorder. Learn about upcoming episodes, mental health resources, and more from our bipolar disorder experts at: https://talkBD.live. Hosted by international bipolar disorder research network CREST.BD.

50 - Psychology of Bipolar Gambling: Why Mania Makes You Risk It All | Dr. Luke Clark | EP 46 🎰
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  • 50 - Psychology of Bipolar Gambling: Why Mania Makes You Risk It All | Dr. Luke Clark | EP 46 🎰

    What happens when mania meets a casino - or a gambling app?


    Award-winning gambling researcher Dr. Luke Clark breaks down the science on why bipolar disorder and gambling are so closely linked, why gambling can feel completely rational during mania, and how modern gambling apps exploit the brain's reward system. Dr. Clark also identifies the highest-risk forms of gambling for people with bipolar disorder and shares evidence-based treatments, practical tools, and strategies to reduce gambling-related harm.


    (00:00) Why Is Bipolar Disorder Linked to Gambling?

    (04:03) Why Gambling Feels Rational During Mania

    (09:26) How Gambling Apps Hijack the Bipolar Brain

    (15:45) Top 3 Most Dangerous Forms of Gambling for Bipolar

    (21:32) Treatments for Bipolar Gambling



    Dr. Luke Clark is a global expert on the psychology of gambling. He joined UBC’s Department of Psychology as the inaugural Director of the Centre for Gambling Research at UBC (⁠https://cgr.psych.ubc.ca⁠) in 2014. Before moving to UBC, he held a tenured appointment in the Department of Psychology at the University of Cambridge. Dr. Clark’s research examines the cognitive and behavioural basis of gambling, and the relevance of these processes to gambling harm and behavioural addiction. His research is distinctive in considering both the personal risk factors for gambling problems, and the psychological effects of modern gambling products. His work combines in lab and online data collection, behavioural analysis, and measurement of psychophysiological responses, including brain imaging.He has published over 200 papers in leading peer-reviewed journals in addiction science, cognitive neuroscience, and mental health, and he has given keynote talks at conferences in Australia, Germany, UK, USA and Sweden. His contributions have been recognized by the Scientific Achievement Award from the International Center for Responsible Gaming (2015) and a UBC Killam Research Award (2021). He holds federal funding from NSERC. In 2023, he was appointed Co-Editor-in-Chief at the journal International Gambling Studies.



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    This episode is hosted by Dr. ⁠⁠⁠⁠⁠⁠⁠⁠Erin Michalak⁠⁠⁠⁠⁠⁠⁠⁠ and produced by Caden Poh.


    #talkBD Bipolar Disorder Podcast

    talkBD gathers researchers, people with lived experience, healthcare providers, and top bipolar disorder experts from around the world to discuss and answer the most important questions about living with bipolar disorder. Learn more about talkBD: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bipolarpodcast.com⁠⁠⁠⁠⁠⁠


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    Fri, 07 Aug 2026 - 27min
  • 49 - Does Bipolar Disorder Age You Faster? ⏳ | Dr. Paula Villela Nunes | talkBD Bipolar Explained

    How does bipolar disorder actually accelerate aging? And what can you start doing today to slow the aging process down?


    Psychiatrist and researcher Dr. Paula Villela Nunes explores the rarely discussed science behind bipolar disorder and accelerated aging, including the role of stress, inflammation, lifestyle, cardiovascular health, telomeres, and increased risk for dementia. She breaks down the hopeful side of the research on how you can take to protect long-term brain health.


    (0:00) Does Bipolar Disorder Make You Age Faster?

    (0:38) Genetics vs Lifestyle Stress

    (1:08) The Science of Telomeres

    (2:09) How to Slow Bipolar Aging

    (2:47) Do Bipolar Medications Speed Up Aging?

    (3:18) Dementia & Lithium


    Relevant readings:

    "Telomere Length and Bipolar Disorder" study (2017): https://nature.com/articles/npp2017125''Does bipolar disorder accelerate cellular aging?" meta-analysis of telomere length (2025): https://pubmed.ncbi.nlm.nih.gov/40803151"ISBD Guide for Older Adults with Bipolar Disorder" (2022): https://www.isbd.org/Files/Admin/Task...

    Bipolar Explained is a new #talkBD series spotlighting expert perspectives on the history, biology, and management of bipolar disorder.

    Dr. Paula Villela Nunes is a psychiatrist, psychotherapist, and researcher whose work focuses on bipolar disorder, aging, and mental health care across the lifespan. Originally from Brazil, she earned her MD and PhD from the University of São Paulo and has worked clinically and academically in both Brazil and Canada. She is currently based in Vancouver, where she works as a researcher at the University of British Columbia.


    Dr. Nunes has a special interest in aging and bipolar disorder, cognitive health, psychotherapy, and non-pharmacological approaches to recovery and wellness. She is a member of the International Society for Bipolar Disorders (ISBD) and serves as chair of the ISBD Older Age Bipolar Disorder Task Force . Her work also explores the role of families and care partners in supporting people living with bipolar disorder, alongside broader efforts to improve mental health awareness and reduce stigma in the community.

    Tue, 19 May 2026 - 04min
  • 48 - Can AI End Bipolar Disorder Misdiagnosis? | Dr. John-Jose Nunez | talkBD Bipolar Explained

    Why does bipolar disorder take years - sometimes decades - to diagnose accurately? And what if artificial intelligence could change that?AI researcher and mood disorder psychiatrist Dr. John-Jose Nunez breaks down the hidden challenges behind bipolar diagnosis and explains how AI could reshape the way we diagnose bipolar disorder. By uncovering new patterns, AI may help doctors see what’s been overlooked - earlier and more accurately than ever before. But how close are we to that reality, and what are the limits?(00:00) AI Is Changing How Doctors Diagnose Bipolar (03:16) How Accurate Is AI? Doctors vs AI(06:50) Human-in-the-loop(09:15) Will AI Replace Psychiatrists?Bipolar Explained is a new #talkBD series spotlighting expert perspectives on the history, biology, and management of bipolar disorder.---Dr. John-Jose Nunez is a psychiatrist and clinical researcher whose work bridges psychiatry and computer science, with a focus on using computational approaches including artificial intelligence, machine learning and natural language processing to improve mental health outcomes. He holds an MD and MSc in Computer Science from UBC, and is a Fellow of the Royal College of Physicians of Canada (Psychiatry). Dr. Nunez is an Assistant Professor at the University of British Columbia, a member of the CREST.BD network, and serves as the Associate Medical Director of Supportive Care at BC Cancer.His research aims to use computational methods like artificial intelligence to help patients with mood disorders such as bipolar disorder and depression, and patients experiencing both cancer and mental illness. His thesis work has led to two high-profile publications in JAMA Network Open and Communications Medicine, which garnered international media coverage. His work has been supported by the UBC Institute of Mental Health and the BC Cancer Foundation. More on Dr. Nunez: https://nunezlab.ca

    Sat, 02 May 2026 - 10min
  • 47 - Do Bipolar Brains Need More Sleep? 🛌 | Dr. Holly Swartz | talkBD Bipolar Explained

    Is it true that people with bipolar disorder have different sleep needs to maintain wellness? How many hours of sleep is optimal? Dr. Holly Swartz breaks down why sleep regularity is so essential for mood stability - and what the science actually tells us.Bipolar Explained is a new #talkBD series spotlighting expert perspectives on the history, biology, and management of bipolar disorder.


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    Dr. Holly A. Swartz is Professor of Psychiatry at the University of Pittsburgh School of Medicine and President of the International Society of Bipolar Disorders (ISBD). She received her undergraduate degree from Harvard College, medical degree from Albert Einstein College of Medicine, and completed her psychiatric residency training at New York Hospital / Cornell University School of Medicine. Dr. Swartz’s research focuses on understanding and optimizing treatments for mood disorders. She is well known for her work evaluating Interpersonal Psychotherapy (IPT) and Interpersonal and Social Rhythm Therapy (IPSRT) as treatments for depression and bipolar disorder. Her research focuses on the role of IPSRT and pharmacotherapy in the management of bipolar II depression and IPT in the management of maternal depression. She is engaged in collaborative projects to develop computational frameworks to model dyadic interpersonal behaviors in relation to psychotherapy process and outcomes and to understand neural correlates of change in chronotherapeutic behavioral interventions. Her research has been funded by the National Institute of Health, National Science Foundation, and the Brain and Behavior Research Foundation.

    Fri, 21 Nov 2025 - 03min
  • 46 - The Evolutionary Secret of Bipolar Disorder 🧬 | Dr. Holly Swartz | talkBD Bipolar Explained

    Why does bipolar disorder exist? And what if bipolar disorder isn’t just an illness, but also an evolutionary adaptation? Dr. Holly Swartz reveals the evolutionary secrets of bipolar disorder - from flexible circadian rhythms that once helped our ancestors survive, to the creativity and boldness often linked with mania.

    (0:00) Evolution

    (0:22) Circadian Control in Nature

    (1:43) Advantages of Flexible Biological Clocks

    (4:48) Risk-Taking & Creativity

    Bipolar Explained is a new talkBD series spotlighting expert perspectives on the history, biology, and management of bipolar disorder.

    --
    Dr. Holly A. Swartz is Professor of Psychiatry at the University of Pittsburgh School of Medicine and President of the International Society of Bipolar Disorders (ISBD). She received her undergraduate degree from Harvard College, medical degree from Albert Einstein College of Medicine, and completed her psychiatric residency training at New York Hospital / Cornell University School of Medicine. Dr. Swartz’s research focuses on understanding and optimizing treatments for mood disorders. She is well known for her work evaluating Interpersonal Psychotherapy (IPT) and Interpersonal and Social Rhythm Therapy (IPSRT) as treatments for depression and bipolar disorder. Her research focuses on the role of IPSRT and pharmacotherapy in the management of bipolar II depression and IPT in the management of maternal depression. She is engaged in collaborative projects to develop computational frameworks to model dyadic interpersonal behaviors in relation to psychotherapy process and outcomes and to understand neural correlates of change in chronotherapeutic behavioral interventions. Her research has been funded by the National Institute of Health, National Science Foundation, and the Brain and Behavior Research Foundation.

    Fri, 07 Nov 2025 - 06min
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