JAMA Medical News

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Waist Circumference Adds to BMI, but Will Clinicians Adopt It?" Related Content:

JAMA Medical News Director Jennifer Abbasi and Staff Writer Samantha Anderer discuss "Is the Pennsylvania Measles Outbreak the New Normal?" Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Testosterone Use Rises Among Women, but Does the Evidence Support It?" Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Lp(a)-Reducing Agent Pelacarsen Misses the Mark in Phase 3—Now What?" Related Content:

JAMA Medical News Associate Managing Editor Kate Schweitzer and Lead Senior Staff Writer Rita Rubin discuss "Unapproved GLP-1 Drugs Retatrutide and Zenagamtide Sold Online Are No Bargain." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss 1 in 5 Children Report Using AI for Emotional Support--Is It Good News or Bad? Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Remove the Fallopian Tubes If the Opportunity Arises, ACOG Says in New Ovarian Cancer Prevention Guidance." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "As More Adults Seek ADHD Care, Primary Care Clinicians Are Tasked With Getting the Diagnosis Right." Related Content:

JAMA Medical News Director Jennifer Abbasi and Staff Writer Samantha Anderer discuss "Is Phage Therapy the Next Big Hope for Urinary Tract Infections?" Related Content:

Hear about a new universal definition of myocardial infarction, updated heart failure guidelines, and other clinical highlights in this interview with Tomasz Guzik, MD, PhD, chair of this year's European Society of Cardiology Congress. Related Content:

The winners of the 2026 Albert Lasker Basic Medical Research Award, Emmanuel Mignot, MD, PhD, and Masashi Yanagisawa, MD, PhD, discuss how they identified the neuropeptide orexin and deduced its role in narcolepsy. Related Content:

JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "Nearly Half of Dementia Cases May Be Preventable—Here's What the Research Says So Far." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Cardiovascular Care Should Incorporate Cognition and Frailty, Heart Group Says in New Statement." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "What the Cyclospora Outbreak Reveals About the State of US Foodborne Disease Surveillance." Related Content:

JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "What to Know About the mRNA Flu Vaccine, Newly Approved by the FDA." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Will New Lyme Disease Approaches Change Patient Care?" Related Content:

Hear the latest on blood-based biomarkers, lifestyle interventions, and more from AAIC 2026 with Gil Rabinovici, MD. Related Content:

JAMA Medical News Associate Managing Editor Kate Schweitzer and Staff Writer Samantha Anderer discuss "A Decade After the CDC's Opioid Prescribing Guidelines, Have Clinicians Struck the Right Balance?" Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Wild West or Gold Rush: How Long-Neglected Menopause Care Has Spawned a Booming Marketplace." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "What to Know About the First CKM Syndrome Guidelines." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Testosterone Therapy: Does New Evidence Warrant Broader Prescribing?" Related Content:

JAMA Medical News Associate Managing Editor Kate Schweitzer and Lead Senior Staff Writer Rita Rubin discuss "First Alzheimer Disease Blood Test May Produce Many False-Positive Results, Study Finds." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "PCOS is Now PMOS—Will a New Name Translate to Improved Clinical Care?" Related Content:

Rita Kalyani, MD, chief scientific and medical officer at the American Diabetes Association, discusses the latest diabetes and obesity research, including a novel oral GLP-1 drug, a combined semaglutide-amylin analogue injection, data from China on high-dose mazdutide, and more. Related Content:

JAMA Medical News Director Jennifer Abbasi and Staff Writer Samantha Anderer discuss "In Obesity Treatment, Physical Activity's Benefits Go Beyond Weight Loss, Says AHA." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Inside the Push for a Fentanyl Vaccine." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "HFpEF May Be a Different Disease in Patients With Severe Obesity." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "A Rare Ebola Virus Is Spreading in the DRC—Here's What to Know." Related Content:

Joining from quarantine, Stephen Kornfeld, MD, discusses his experience stepping in as the ship's physician when hantavirus transformed his vacation cruise into a global public health concern. Related Content:

JAMA Medical News Director Jennifer Abbasi and Staff Writer Samantha Anderer discuss "More Than 19 000 Measles Cases in a Month—What the Current Outbreak in Bangladesh Signals to the World." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Experts Debate How Obesity Should Be Defined and Diagnosed." Related Content:

JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "These Blood Tests May Detect Dozens of Cancers, but Will They Save Lives?" Related Content:

JAMA Medical News Associate Managing Editor Kate Schweitzer and Staff Writer Samantha Anderer discuss "Weight Loss, Adverse Effects With GLP-1 Medications May Be Influenced by Genetics." Related Content:

JAMA Medical News Associate Managing Editor Kate Schweitzer and Staff Writer Samantha Anderer discuss "Could a Common Antidepressant Help Treat Methamphetamine Use Disorder?" Related Content:

JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "What to Know About Cicada, or BA.3.2, the Latest SARS-CoV-2 Variant Under Monitoring." Related Content:

Hear the latest on PCSK9 inhibitors, cardiorenal benefits of GLP-1 drugs, and other clinical research in this interview with Katie Berlacher, MD, MS, chair of this year's annual ACC meeting. Related Content:

JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "How mRNA Vaccines Could Help Treat Cancer." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "New Hope for Patients With Advanced Alcohol-Related Cirrhosis Who Stop Drinking." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "What to Know About the New Lipid Guidelines." Related Content:

JAMA Medical News Associate Managing Editor Kate Schweitzer and Staff Writer Samantha Anderer discuss "Why the EPA's Reversal on Heavy Metal Air Pollution Is Cause for Concern." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "After a Decade of Progress Against HIV, PrEP Enters a Precarious Era." Related Content:

JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "Are AI Tools Ready to Answer Patients' Questions About Their Medical Care?" Related Content:

JAMA Medical News Associate Managing Editor Kate Schweitzer and Staff Writer Samantha Anderer discuss "In the Low-Carb vs Low-Fat Debate, Study Suggests Food Quality Matters More for Heart Health." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "What Nutrition Experts Say About the New Dietary Guidelines for Americans." Related Content:

JAMA Medical News Associate Managing Editor Kate Schweitzer and Lead Senior Staff Writer Rita Rubin discuss "US Patients Getting ICE-d-Out of Health Care." Related Content:

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "Mechanisms Are Emerging for COVID-19 Vaccine−Associated Myocarditis." Related Content:

JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "Data on 3 New GLP-1 Drugs for Weight Loss That May Be Approved This Year." Related Content:

In this week's roundup, Associate Managing Editor Kate Schweitzer and Lead Senior Staff Writer Rita Rubin discuss "Stress May Link Depression and Anxiety to Cardiovascular Disease." Related Content:

In this week's roundup, JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "What to Know About the Wegovy Pill for Obesity" and more. Related Content:

In this week's roundup, JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "What to Know About the WHO's New GLP-1 Guideline" and more. Related Content:

In this week's roundup, JAMA Medical News Director Jennifer Abbasi and staff writer Samantha Anderer discuss "Can Nicotine Pouches Help People Quit Smoking?" and more. Related Content:

In this week's roundup, JAMA Medical News Associate Managing Editor Kate Schweitzer and freelance writer and Harvard medical student Emily Harris discuss "A Growing Movement Aims to Prepare All Physicians to Care for Older Adults" and more. Related Content:

In this episode, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Medical News Director Jennifer Abbasi discuss the journal's inaugural Research of the Year roundup. Related Content:

Updates on coffee and AFib, a polypill approach for HFrEF, the first oral PCSK9 inhibitor, vitamin D supplementation for secondary prevention, and more: Joanna Chikwe, MD, chair of the American Heart Association's Scientific Sessions conference and of the Department of Cardiac Surgery in the Smidt Heart Institute at Cedars-Sinai Medical Center, shares clinical research highlights from the recent meeting. Related Content:

Correction: an earlier version of this podcast misstated the phosphorylated tau analyte measured by the Roche blood biomarker test. It is p-tau181, not p-tau217.

In this week's roundup, JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "Alzheimer Disease Blood Test Cleared for Primary Care, but Questions Remain About Its Use" and more. Related Content:

Updates on SGLT2 inhibitors, fish oil and hemodialysis, GLP-1 drugs, and more: Katherine R. Tuttle, MD, education committee co-chair of Kidney Week 2025 and a professor of medicine at the University of Washington, shares clinical research highlights from the recent meeting. Related Content:

In this week's roundup, JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss "US Governors Are Forming a Public Health Alliance Amid Federal Funding Cuts and Shifting Guidance" and more. Related Content:

In this weekly roundup, JAMA Medical News Director Jennifer Abbasi and Lead Senior Staff Writer Rita Rubin discuss "MASLD—The Chronic Liver Disease That Affects Tens of Millions of US Adults but Flies Under the Radar" and more. Related Content:

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In this weekly roundup, JAMA Medical News Director Jennifer Abbasi and Staff Writer Samantha Anderer discuss "Peanut Allergies Appear to Be on the Decline Following Early Introduction Guidelines" and more. Related Content:

Dementia is still a highly stigmatized condition. Nancy Berlinger, PhD, a senior research scholar at The Hastings Center for Bioethics, discusses a new report about the cultural narratives of dementia and how they can affect the quality of life and the care of patients with the condition. Related Content:

State Laws Aim to Bring Internationally Trained Physicians to Underserved Areas, but Barriers Abound; Oral Microbiome Composition Linked to Pancreatic Cancer Risk Related Content:

A new European Society of Cardiology clinical consensus statement deals with cardiovascular disease prevention and management in COVID-19, including cardiac long COVID. The report's lead author, Vassilios Vassiliou, MBBS, PhD, MA, discusses the guidance and key questions that remain about COVID-19 and the heart. Related Content:

Epidemiologist Brian Lee, PhD, discusses his study on acetaminophen use during pregnancy and children's risk of autism and other neurodevelopmental disorders in this interview with JAMA Deputy Editor Linda Brubaker, MD. Related Content:

Ultraprocessed Foods and Cardiometabolic Health—New Report on a "Growing Public Health Challenge"; New Analysis of Women's Health Initiative Data Aims to "Clear the Air" Over Menopausal Hormone Therapy Related Content:

Updates on GLP-1 drugs in heart failure, β-blockers after myocardial infarction, the shingles vaccine, and more: Felix Mahfoud, MD, chair of the Department of Cardiology at University Hospital Basel, shares clinical research highlights from the recent European Society of Cardiology Congress. Related Content:

Pulmonologist Michael J. Welsh, MD, is the co-recipient of the 2025 Lasker-DeBakey Clinical Medical Research Award for his research on cystic fibrosis. In this interview, he discusses his early clinical encounters with the disease, the foundational work that led to the lifesaving drug Trikafta, and future directions for cystic fibrosis treatment. Related Content:

What Is 7-OH?; Real-World Experience With Antiamyloid Therapies for Alzheimer Disease; FDA Panel on SSRIs and Pregnancy Lacked Nuance, Experts Say Related Content:

The Effects of Newly Changed Guidance on COVID-19 Shots During Pregnancy; Heart Disease Deaths Have Changed; Progress Toward a Norovirus Vaccine Related Content:

In this follow-up to a 2017 interview with JAMA Medical News, the University of Southern California's Maja Matarić, PhD, the computer scientist who pioneered the field of socially assistive robotics, discusses how artificial intelligence is advancing the field in areas ranging from autism to physical rehabilitation to anxiety and depression. Related Content:

Kimmie Ng, MD, MPH, a JAMA associate editor and associate chief of the Division of Gastrointestinal Oncology at the Dana-Farber Cancer Institute, shares highlights from the American Society of Clinical Oncology's annual meeting, including new research on diet, exercise, and cancer survival and the best time of day for treatment. Related Content:

New NIH-FDA Partnership Targets Nutrition Research Gaps; First Blood Test for Alzheimer Biomarkers Receives FDA Clearance; A Growing Movement to Care for Caregivers Related Content:

Delaying diagnosis of parkinsonism can mean delaying care. In a study recently published in JAMA Neurology, David Vaillancourt, PhD, and colleagues tested the ability of an AI model to differentiate between Parkinson disease and other neurodegenerative disorders when paired with MRI. He joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH to discuss. Related Content:

Federal Funds for Rural Health Care May Be Cut; Why the IV Fluid Shortage After Hurricane Helene Was Years in the Making; Surge in US Sports Betting Raises Public Health Concerns Related Content:

Susan Athey, PhD, of Standford University joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss her research on machine learning to target behavioral nudges for college students and their potential implications for health care. Related Content:

Ajay J. Kirtane, MD, SM, a professor of medicine at Columbia University Irving Medical Center, discusses late-breaking clinical research presented at the annual meeting of the American College of Cardiology in an interview with JAMA Medical News Director Jennifer Abbasi. Related Content:

Axe Falls on Federal Health Workforce; Experts Say CDC Cuts Will Cost Lives Related Content:

Diabetic retinopathy remains a leading cause of preventable blindness worldwide, and AI may facilitate screening, if such models continue to perform well when they are deployed in the real world. Coauthors Arthur Brant, MD, of Stanford University, and Sunny Virmani, MS, of Google join JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss a new study published in JAMA Network Open. Related Content:

Correction: This podcast has been updated to add additional context on the frequency of false positives. Open neural tube defects affect approximately 1 in 1400 births. Daniel Herman, MD, PhD, of the University of Pennsylvania Perelman School of Medicine joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss a quality improvement study examining the need to continue to incorporate race in tests that screen for these defects. Related Content:

A recent study published in JAMA Health Forum suggests that institutions may be able to deploy custom open-source large language models (LLMs) that run locally without sacrificing data privacy or flexibility. Coauthors Thomas A. Buckley, BS, and Arjun K. Manrai, PhD, from the Department of Biomedical Informatics at Harvard Medical School join JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss. Related Content:

The US Is Suing Pharmacies for Aiding in the Opioid Crisis; Texas Measles Outbreak Spurs Call for Stronger Vaccine Advocacy; Study Finds Sleep-Related Infant Deaths Are on the Rise Related Content:

Artificial intelligence (AI) in health care is advancing, despite concerns about how its use may impact health disparities. Dimitri Christakis, MD, MPH, chief health officer at Special Olympics, joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to discuss AI's potential role in improving health care delivery for people with intellectual and developmental disabilities. Related Content:

A recent study showed AI-assisted screening using a large language model tool reduced time to determine trial eligibility compared with manual methods. Author Alexander J. Blood, MD, MSc, cardiologist at Brigham and Women's Hospital, and Associate Director of the Accelerator for Clinical Transformation Research Group at Harvard Medical School joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to discuss this topic and more. Related Content:

In a recent study published in JAMA Psychiatry, researchers reported that a machine learning model was able to stratify risk for subsequent diagnosis of schizophrenia or bipolar disorder among individuals already receiving psychiatric treatment. Coauthor Søren Dinesen Østergaard, PhD, of Aarhus University in Denmark joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss. Related Content:

AI can play a role in addressing language barriers in health care. In a recent Editorial in JAMA Network Open, Pilar Ortega, MD, MGM, of the University of Illinois College of Medicine, and coauthors emphasized the urgent need for integrating language equity into digital health solutions. Dr Ortega joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, to discuss. Related Content:

A recent report from the Engineering Research Visioning Alliance emphasizes the urgent need for engineering-directed research to mitigate the growing threat of antimicrobial resistance. Anita Shukla, PhD, a professor of engineering at Brown University, discusses its findings with JAMA Medical News Associate Managing Editor Kate Schweitzer and presents several key opportunities. Related Content:

Changes to CDC's Website Threaten Patients, Public Health; Landmark Study of Black Women and Cancer Launches Related Content:

Lung ultrasound aids in the diagnosis of patients with dyspnea but requires technical proficiency for image acquisition. Cristiana Baloescu, MD, MPH, of Yale School of Medicine, joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to discuss a new study published in JAMA Cardiology evaluating the ability of AI to guide acquisition of diagnostic-quality lung ultrasound images by trained health care professionals. Related Content:

A recent study in JAMA Network Open evaluates the use of machine learning algorithms to assess the management of urinary tract infection (UTI). Author Sanjat Kanjilal, MD, MPH, professor in the Department of Population Medicine at Harvard Medical School and Harvard Pilgrim Healthcare Institute, joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to discuss this topic and more. Related Content:

Digital health technologies, including patient portals, are widely used by older adults, as described in a recent study published in JAMA Network Open. Author Cornelius James, MD, of the University of Michigan joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss the study and how it fits with his own experience in the clinic. Related Content:

How do patients feel about the quality of AI-generated responses to their messages to clinicians? Author Eleni Linos, MD, DrPH, of Stanford joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss her recent study in JAMA Network Open that characterized satisfaction with these messages. Related Content:

Weight-Loss Drugs Are Reshaping the Future of Bariatric Surgery; Are Compounded GLP-1 Drugs Safe? Will Renaming Some Cancers as Noncancers Hurt or Help? Related Content:

The burden of responding to clinician inbox messages may be a contributor to burnout. Eden English, MD, of UCHealth joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss her recent study published in JAMA Network Open, which examined the use of large language models to reply to patient messages. Related Content:

With accelerating global adoption of AI, countries are developing ethical AI frameworks to prevent harm to the most vulnerable populations. Maria Villalobos-Quesada, PhD, from the National eHealth Living Lab (NeLL) in the Netherlands and the Observatory of Bioethics and Law of the University of Barcelona, discusses this and more with JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH.

*Author image and affiliations updated February 4, 2025. Related Content:

American Indian and Alaska Native communities have higher rates of suicide than any other racial or ethnic group in the US. A recent study published in JAMA Network Open describes an AI-based suicide screening tool investigated in an American Indian community. Author Emily Haroz, PhD, of Johns Hopkins Bloomberg School of Public Health, joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH. Related Content:

How can hospitals use early warning score tools to risk stratify patients without adding to alarm fatigue? Dana Edelson, MD, MS, of the University of Chicago joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss a recent study published in JAMA Network Open that she coauthored, comparing 6 early warning scores designed to recognize clinical deterioration in hospitalized patients. Related Content:

Chatbots may have a role in enhancing clinical care, but the best way to apply them remains a work in progress. Jonathen Chen, MD, PhD, and Ethan Goh, MD, MS, of Stanford, join JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, to discuss their randomized clinical trial published in JAMA Network Open investigating the use of chatbots in clinical practice. Related Content:

Why COVID-19 Vaccines Don't Stop Transmission; Hospital-at-Home—But Make It Virtual Related Content:

In a recent Viewpoint published in JAMA, Michael Pencina, PhD, of Duke University, argued for a federated registration system for AI tools deployed in health systems. He joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss his article, the Coalition for Health AI (CHAI), and more. Related Content:

In resource-limited settings, an integrated AI tool allows novice users to improve gestational age estimates. Jeffrey Stringer, MD, University of North Carolina, joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss "Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps." Related Content: