Health Report - Full program podcast

Is a simpler solution to recurrent UTIs on the way? Plus when should you exercise to get the most benefit? A deep dive into the UK's reviews of gender affirming treatment, and how Australia's system differs.  Researchers say there's more PFAS in our water than previously thought, but how much do we know about the health harms? And a new way to deliver immunotherapy straight to the source in bladder cancer.

In health news this week it's cows with bird flu, vaccines for human flu, and GLP-1s for Parkinson's and possibly bowel cancer prevention. When your private health insurer won't pay, have you read the fine print on your policy lately? A look at health literacy barriers, when it's not the apple a day keeping some people away from the doctors' office. How mRNA technology developed during COVID is now being used to target the proteins that cause Alzheimer's and dementia. And new technology allowing researchers to look beyond standard autopsy results to investigate possible causes of some cases of SIDS.

How changes to codeine access impacted the use of PBS-listed opiods.  Pinpointing particular strains of bacteria that could lead to bowel cancer.  The Australian research that helped change our definition of anaemia.  And why aren't there already strict guidelines on indoor air quality?

Three recent scientific papers looking at ADHD treatment and other health outcomes. Why no one knows what your cancer treatment will do to your ovaries. In a small US study, brain cancer tumours shrank rapidly in the first few days when treated with chimeric antigen receptor, or CAR, T cells injected into the fluid around the brain. And suicidal thoughts are more common than researchers expected in people who do not fit with conventional diagnoses of depression or other psychiatric disorders.

Queensland's Chief Health Officer says the term "long-COVID" should be scrapped, but there are different definitions of what long-COVID is and different ways data is collected Evidence suggests toddler or transition milks are unnecessary at best and harmful at worst. Numbers of alcohol related deaths may have been under reported because past abuse isn't captured when a reformed-drinker dies.

A 62-year-old man in Germany—called HIM—deliberately received the SARS-CoV-2 vaccination 217 times within a period of 29 months. Researchers were keen to know how he fared. Sleep has become a bit of an obsession and has us questioning just how much we need. A large study has compared participants' duration of sleep against their risk of Type 2 Diabetes. In pop culture and news coverage menopause and mood changes seem inextricably linked. A special series on menopause has just been published in the Lancet, with one paper specifically on mental health. In hospital emergency rooms emotions can run high, and tempers can get frazzled, which is confronting for both staff and other patients.

Major depressive disorder is a leading cause of global disability, and exercise looks like a candidate for treatment. But which type? Skin cancer is a major health risk for Australians, but access to proper cancer screening and treatment is difficult, especially in some of our highest-risk areas, like Far North Queensland. Sarcoidoisis is an enigmatic condition that may attack different parts of the body. Diagnosis is difficult and there are few treatments. It's now being comprehensively researched.

When COVID vaccines first became available in 2021, they were met with celebration. Finally we had some defence against this virus that had struck down so many and triggered such heavy lockdowns. But once they started rolling out en masse, a new concern emerged – reports of side effects that, while rare, could be severe.  Just how rare these conditions are has now been better described by a new paper drawing on data from 99 million people from across the world.  The answer – as we already suspected, there is a link between the vaccines here in Australia and conditions like heart inflammation, blood clots and a usually temporary paralysis called Guillian-Barre syndrome, among others. But the data also show the risk of those conditions is small in comparison to the risk of the same conditions in someone who actually catches COVID.  References: COVID-19 vaccines and adverse events of special interest: A multinational Global Vaccine Data Network (GVDN) cohort study of 99 million vaccinated individuals

News this week is The Government response to the long COVID inquiry, which looked into how many Australians are living with long COVID and what could be done to support them. And, a report on fine particulates in the air, and their relationship with coronary heart disease. A study has tested whether showing people actual pictures of the plaque inside their arteries is more persuasive than a simple risk score in promoting healthy changes. Turns out, it is. A senior cardiologist calls it The Hidden Killer, and it may contribute to about 50% of heart attacks, especially people who may be younger and with relatively normal cholesterol levels. It’s called Lipoprotein(a) or Lp(a). New data is showing that, for children, any contact with the criminal justice system means they’re more likely to die earlier, and have health problems of every kind. Are kids already at risk more likely to be targeted by the system—what would change this trend?

Health news: Insomnia: what kind of therapy and/or behaviour changes are more likely to work? And new advice on sun exposure that reflects Australia's diverse population. Low-carb diets have grabbed a lot of attention, promising weight loss and improved health, but they're not all the same. Diet is important for health, but foods high in sodium are a risk factor for high blood pressure, and stomach cancer. In early 2022, after nearly two years of the COVID pandemic, doctors started to notice another alarming trend: severe and unexpected liver disease in children all over the world. Some activities really make us feel good—like working up a sweat, or connecting with people. Might it be possible for a doctor to prescribe such activities?

A groundbreaking study from the Queensland Brain Institute has found serious deficiencies in the amount and quality of food provided to kids by Early Childhood Education and Care (ECEC) services. This can compromise kids' nutritional needs, and brain development. Getting a diagnosis for autism for a child or adolescent is a series of complicated and often expensive hoops to jump through—and it’s even harder for adults.

The addictive painkiller fentanyl has swept through the USA—but its effects haven't been as big in Australia. Why? Vaccination against COVID-19 can save lives and reduce the risk of severe disease. Why are some people under vaccinated—and what's the risk for people not up to date with shots? An early form of breast cancer—ductal carcinoma in situ (DCIS)—is often found by women themselves, not as part of screening programs. The power and potential pitfalls of AI in medicine have been debated, but AI is already having an impact in radiology.

The drug name on everyone’s lips is semaglutide—a seemingly magical substance that can solve all our ills. But it’s not just semaglutide, there’s a whole class of drugs called GLP-1 agonists. Opioids are commonly prescribed to patients who have cancer to help them with pain, but the drugs are not risk free and can have their downsides. Last year there was a Senate report into the state of dental care in Australia, and like a visit to the dentist—it wasn’t a fun read. Back pain affects so many people – but when doctors look at it, they find that while some people recovery quickly other continue to suffer in silence and agony. v

What's happening with COVID Australian vaccination rates are dropping A new term for chance discoveries on scans

The shock of a cancer diagnosis is familiar for far too many people. But when Na'ama Carlin was diagnosed with breast cancer, her health wasn't the only consideration.  If you're in need of support you can contact Mummy's Wish or Hope for Two.

First heard in July 2023 It’s called ‘young onset’ dementia if diagnosed before the age of 65—and can occur while people are still caring for kids and supporting a household. First heard in July 2023 We think breastfeeding is quite natural, but it doesn’t always come easily, and some issues—such as Breastfeeding Aversion Response (or BAR)—are still under-researched.

Drug use has been increasing, whether it be cannabis, cocaine, ecstasy, hallucinogens, or ketamine. That includes recreational use and substance abuse. So it begs the question: Has criminalising drugs ever worked? And what needs to be done to drive down the harms associated with this increasing drug use? If you're in need of support, you can contact the National Alcohol and Other Drug hotline on 1800 250 015, or contact Counselling Online.

A new kind of ADHD clinic is cashing in on surging demand for diagnoses—and promising salaries of more than $900,000 to recruit psychiatrists. As the need for services has grown, so have waitlists. Given the choice between a ChatGPT bot or a real doctor, a panel of health care professionals found the bot's responses were both more empathetic and gave higher quality information.

More and more people are tackling the bracing discomfort of ice bath sessions. Alongside several touted health benefits there are some serious risks. Norman is at Bronte Beach to chill. Researchers observed the cardiac and neural signals from a small number of ICU patients at the point when ventilatory support was withdrawn. They recorded the quite new phenomena of electrical activity in a particular area of the brain. Keeping motivated to exercise can be difficult, but for people getting over a traumatic brain injury it's even more so. An exercise program at Liverpool Hospital uses gaming to encourage activity.

Feeling dissatisfied with their appearance can become an obsession for some people, and affect quality of life and relationships. Most people can benefit from reduced salt intake, and so reduce the risk of heart attack, atrial fibrillation, stroke, dementia, and kidney damage. A few months ago the program there was a story on an under-recognised cause of high blood pressure called primary aldosteronism. One listener asked to be tested. An area of Australian healthcare that might be a candidate for review is drug subsidy. We might consider what New Zealand's PHARMAC does, and conduct a competitive tender.

Bringing clarity to health and medical issues from social, scientific and political points of view.

There are eerily familiar of clusters of respiratory infections being reported across China. We know that for some health conditions women are more likely to have a worse time than men. But for the anterior cruciate ligament (ACL), the chances of a woman sustaining an injury to it are up to 6 or even 10 times as likely as men. When someone has a complex or severe mental health issue, the specialist they really need is a psychiatrist. However, GPs are finding it now more difficult to track down a psychiatrist to accept their patients.

Another COVID wave, another COVID vaccine and another episode of Coronacast ... sort of? Norman and Tegan will be providing coronavirus updates when needed, so subscribe to The Health Report feed so you don't miss out! References: The unequal effects of the health–economy trade-off during the COVID-19 pandemic

In 2016 Australia legalised cannabis for medicinal use and now the Greens party are advocating for its recreational use as well. The Australian Medical Association say that would send the wrong message. Antimicrobial resistance has been described an emerging public health emergency. A major cause is overuse of antibiotics and other drugs to combat microbes, like fungi. When a baby is born premature time is of the essence, and the idea of slowing things down in those first few moments seems counter-intuitive.

In March 2023 a Senate inquiry began to review how the health system manages people with ADHD, and the Government has now three months to respond. The ABC's Birth Project invited people to share their experiences of birth in Australia—and if improvements could be made to the system. The responses indicate that there's plenty of scope Yellow Fever is spread by mosquitoes, and some U.S. researchers say that it's ripe for a comeback. The same species of mosquito is already either in Australia or nearby. The latest report on what we're spending on health in Australia has offered a clear picture of what COVID has cost. What's that rash contact details: What's that rash email: thatrash@abc.net.au on Instagram @abcheal

If we don't get enough sleep we're apt to doze off in the day, but for some people, dozing off can signal rare disorder of the brain's sleep-wake cycles, and it plays havoc with their lives. In one 24-hour period our body undergoes a number of synchronised  biological changes, which are also linked to our mental health.

A question asked about COVID-19 was whether high doses of intravenous vitamin C could fight it. Two randomised controlled trials showed no benefit for COVID-19. But high-dose Vitamin C can benefit cancer treatment. Arthritis of the hands is common, painful, a bit of a mystery, and hard to treat. Researchers have trialled a drug commonly used for rheumatoid arthritis, and found some benefit. In Victoria, hospital researchers have been watching how COVID and lockdowns affected births there. Some hospital adaptations persisted well past the lockdown phases—including shorter hospital stays after birth. Blood cancers often affect people younger than the average person who develops cancer, and Australian and New Zealand haematologists have been pioneers in trialling new treatments—this year marking the 50th anniversary of the clinical trial group that coordinates studies.

Two of the most common causes of death in Australia, and globally, are stroke and dementia. One cause of stroke is atrial fibrillation—an abnormal heart rhythm—it may also cause dementia. Faecal microbe (or poo) transplants are something we've talked about on the program, but until recently, they've not been widely available. In fact, the product is made in Australia. Australia is to participate in a survey of the experiences of patients in general practice who have a chronic illness.

Post-traumatic stress disorder (PTSD) is an extreme form of anxiety caused by the laying down of bad memories when someone is involved in a threatening situation. A new treatment has been developed for people to write about their experience, and feelings about the memory. Having your blood pressure checked at the doctor's or hospital is a health care basic. A recent trial has found a significant and possibly unexpected source or error: the size of the cuff, relative to the thinness or thickness of your upper arm. For people with cancer, being offered a place in a clinical trial can provide hope of a better outcome, but trial participants are far less likely to be from culturally and linguistically diverse backgrounds than the general population. Hosts: Dr Norman Swan and Tegan Taylor

Australians will soon vote on changing the Australian Constitution to recognise First Nations people—the Voice to Parliament. When it comes to health, there's a strong evidence base for the Voice. In a slightly edited form, we hear again a conversation from a few weeks' ago with two key people working in this area. Over the past two decades, deaths from cardiovascular disease among people with diabetes have gone down, but is revealing other trends

3D printing is becoming an incredibly versatile modern tool—there’s scope  in engineering, manufacturing, architecture and design—as well as in several aspects of health care. Today we tour the Herston Biofabrication Institute—part of the Royal Brisbane and Women’s Hospital—where clinicians, academics, and industry work together in a state of the art facility.

To have you in the best physical condition before major surgery many surgeons send you for a pre-operative assessment by a physician—does it help? When a child has persistent cold symptoms, it might be sinusitis and require antibiotics. If a child faints it's really only a worry when it causes an injury. But there might be an abnormality of the heart's electrical system, called congential Long QT syndrome, and prompt parents to have their child checked.  Rehab after knee replacement is controversial because some hospitals keep you in for it, but if you go home soon after the surgery, maybe digital rehab will become an option.

Humans spend around a third of their lives sleeping, and its management has created a multi-million dollar industry. We discuss the sleep of FIFO workers, the sleep of people with PTSD, and what we can do to improve our shut-eye time with a therapy called circadian medicine.

A clearer picture of where and how mistakes are made in medical diagnoses. Monkeys on some Caribbean islands are helping researchers understand more about addiction. Sydney's Liverpool Hospital developed a program using gaming to spur on patients recovering from traumatic brain injury.

Australia's had probably its first conference on Long COVID. The idea of a worm infection evokes a visceral response—but there are potential health benefits to worms. GPs may hesitate to approach a discussion about weight loss because of the risk of body shaming and stigma.

Mexico has implemented labelling of processed foods with large warnings if the unhealthy ingredients exceed globally agreed thresholds. New research has been looking into why sitting is bad—and how to change that. Women are being mislead by fertility tests which promote anti-Mullerian hormone—or AMH testing—which are not designed for general screening in the community. One of the side effects of having had babies and ageing in general is what used to be called prolapse—or uterine descent. Sometimes no treatment is needed but there's been a debate among surgeons about which procedure is best.

We heard today about a new test for ovarian cancer.  For a long time there's been a search for a way to reliably detect this cancer early on. Some men are prescribed testosterone-replacement therapy in middle age or older, but there's questions around how safe that is for their heart attack and stroke risk. In developing the cervical screening program one woman—Mary Papanicolaou—did a test every day, for 21 years—it's what we now call the PAP test. People tend to think they need seven or eight hours sleep a night. But what counts more is the quality of that sleep.

Measuring activity on Cradle Mountain—Norman and Tegan rise to the challenge. Polycystic Ovary Syndrome—a new guideline for doctors and women. Vigorous Incidental Lifestyle Physical Activity—micro-bursts of it can decrease the risks of developing various cancers. Cochlear implants—the latest intel on this transformative tech. As part of National Science Week.

wide health implications. The remote community of Balgo in the Tanami Desert has many years of hunting for bush tucker. People must leave their Country if they want dialysis care, but that's changing.

Metastatic cancer is for the spread of a cancer from a primary site to other parts of the body. There's no nationally consistent way of keeping track of how many of these cancer patients there are. A consortium of Australian cancer researchers has announced a program called the PrOSPect Initiative. It offers genetic profiling for people with advanced or rare cancers. Aerobic exercise reduces blood pressure, and resistance training prevents progression to diabetes in people at risk. But the evidence is being updated on which exercise is best for lowering blood pressure. Various studies show that regular aerobic exercise reduces blood pressure, and resistance training prevents progression to diabetes in people at risk of metabolic disease. But the evidence on which kinds of exercise are best for lowering blood pressure is being updated.

To assess the heart health and stroke risk factors of the population, Australian GPs and cardiologists have referred to a study from the population of Framingham, Massachusetts, but last week the Heart Foundation replaced it with a tool based on New Zealand and Australian populations. An abnormal heart rhythm can mean observations by a cardiologist with a cumbersome and expensive Holter monitor. A team at Westmead Hospital and the University of Sydney have compared a simple finger electrode linked to your mobile phone against Holter monitoring. Red and processed meats have an environmental cost and health implications. The World Health Organisation has flagged that, globally, we need to consume less. We discuss the evidence for cutting back, and what it could mean for Australia—a big producer and consumer of these meats.

In health news Norman and Tegan discuss changes in the health system for medical termination of pregnancy; and about life span vs life expectancy in Australia. Alongside MDMA and psilocybin as treatments for mental health issues is ketamine—which shows promise in treatment-resistant depression. A common fracture in children comes from a fall onto an outstretched arm. Parents instinctively want to get an X-ray but an ultrasound can work just as well for most these cases.

Strength training is fundamental to most athletes' regimes, but the guidelines are overwhelmingly based on male data. An analysis of labelling on sports foods—things like protein shakes and bars—finds that the nutritional claims they make often don’t tally with the ingredients panel. Worry about memory loss is not uncommon, and not confined to an older age group, but measuring memory accurately needs refinement. Many Australians are prescribed opioids as relief for back pain, but the a world-first trial led by the University of Sydney found that opioids don't offer significant benefit and guidelines for their use need to be changed.

If dementia is diagnosed before someone is 65 it's called 'younger onset' dementia, and it can occur while people still have family responsibilities. We talk with people who have been given this news, and to researchers looking to improve diagnosis and care. We think of breastfeeding as being quite natural, but it doesn't always come easily, and issues such as Breastfeeding Aversion Response (or BAR) are still under-researched.

A look at some of the big stories in health over the last week ... cough syrup, Duchenne gene therapy; chemo drugs in the US. Some new prescribing guidelines for opioids recommend an exit strategy—and the need for better support infrastructure. It was suspected that brain damage for some people with Parkinson's disease was due to chemical toxins—one of the probable culprits is an environmental contaminant. Having your tonsils out as a child used to be routine, but what about for adults? British authorities noticed an increase in tonsillectomy rates—which prompted a clinical trial to see if the surgery was merited.

A recent bus crash in the Hunter Valley claimed 10 lives. Trying to make sense of such tragic events often prompts a reach for advice that sounds right, but might not be. Therapy using psychedelic drugs is generally safe yet a review of its use found that adverse events were not properly assessed or not reported. In Canada cannabis was legalised 5 years ago for non-medical and recreational use. Public health researchers have asked if this legalisation had health impacts on mothers and their babies if it was used during pregnancy—and how those babies were affected. An Australian clinical trial found that a form of psychotherapy called Cognitive Functional Therapy could help people with chronic disabling low back pain.

Bringing clarity to health and medical issues from social, scientific and political points of view.

A recent study has looked at correlations between rates of (Australian) population obesity and searching online for anti-obesity and diabetes drugs—searches for a class of drugs called the GLP-1 agonists. You probably know the Australian Government has general exercise recommendations for adults, but what if you're in a high risk group? Does that change the amount of activity you should be doing? Peripheral arterial disease (PAD) is perhaps the ‘poor cousin’ of cardio-vascular disease. PAD puts people at risk of heart attack, stroke and amputations, and a really disturbing review of what's known about it in women finds it to be underdiagnosed and undertreated.

A new kind of ADHD clinic is cashing in on surging demand for diagnoses — and promising salaries of more than $900,000 to recruit psychiatrists.

The World Health Organisation has advised against artificial sweeteners for weight loss because they offer no long-term benefits. Australian research has found a link between diets high in ultra-processed foods and an increase in risk of depression. Healthcare is a large greenhouse gas emitter, but how do we reduce its environmental impact without compromising on health?

The U.S. Food and Drug Administration (FDA) have voted that when they meet formally at the end of May, approval goes forward for a treatment for Duchenne muscular dystrophy—a disabling genetic disease. Post partum depression is a significant issue for both women and their babies, and it doesn't come out of the blue—depression can occur before or during pregnancy. Child neglect leads to both later poor physical health—with things like inflammation—and mental health, such as depression. Would you wear protective eyewear to play tennis, badminton or Aussie Rules?

When given the choice between a ChatGPT bot or a real doctor, a panel of health care professionals found the bot's responses were both more empathetic and also higher quality information. A study on the effect of hormonal contraception suggests that a history of hormonal contraceptive-associated depression could be a risk indicator of postpartum depression. Last week the Minister for Health and Aged Care announced over $500 million for a national lung cancer screening program. It targets high-risk individuals in the early stages.

Bringing clarity to health and medical issues from social, scientific and political points of view.

Bringing clarity to health and medical issues from social, scientific and political points of view.

Drug use has been increasing, whether it be cannabis, cocaine, ecstasy, hallucinogens or ketamine. That includes recreational use and substance abuse. So it begs the question: Has criminalising drugs ever worked? And what needs to be done to drive down the harms associated with this increasing drug use? If you're in need of support, you can contact the National Alcohol and Other Drug hotline on 1800 250 015, or contact Counselling Online.  Credits Abigail Leeder, Reporter Shelby Traynor, Producer

The shock of a cancer diagnosis is familiar for far too many people. But when Na'ama Carlin was diagnosed with breast cancer, her health wasn't the only consideration.  If you're in need of support you can contact Mummy's Wish or Hope for Two.

More people are injecting drugs than ever before. So what are the harms, and what are we doing to minimise them? People with schizophrenia have a life expectancy 25 years younger than the average Australian, and one of the reasons is heart attacks.  Meanwhile, do surgeons need to change their approach to coronary bypass surgery?  And Australian researchers uncover a potential new treatment for a rare blood disorder — that could replace blood letting.

Australia's bone marrow donor registry is funding a cheek swab program to recruit more donors, as it awaits government funding.  Also, the latest in alopecia treatment for those who want to reverse hair loss — and the perspective of those who don't.  And prostate cancer screening can be imprecise and invasive. Could delving into the genome help narrow things down?

Discussing the importance of addressing social determinants of health with a pioneer for health equity.  Should vaping products be banned? Many young Australians are getting addicted to nicotine without always being aware that's what they're consuming.  And eye drops could be used to slow the progression of short-sightedness, which is on the rise thanks to our screen-dominated world.

The debate continues on whether the TGA acted too soon on the rescheduling of psilocybin and MDMA for the treatment of some mental illnesses.  Calls for Australia's cardiovascular disease guidelines to recommend coronary calcium scoring for patients at intermediate risk.  And did you know ovarian cancer often originates in the fallopian tubes? A simple surgical procedure could drive down cases.

How much screen time is too much for young kids? Taking a looking at what digital playtime is doing to children's brains.  Calls for better models of care for people living with lymphoedema, to avoid deterioration and costly hospital stays.  And organ donation is yet to fully recover from a pandemic-driven dip. Why aren't more people consenting?

Mind Medicine Australia share their thoughts on the recent approval of psychedelic compounds for treatment-resistant depression and PTSD.  A study in Sweden has looked at a possible association of maternal and paternal primary antibody immunodeficiencies — and if this provides a natural test of a hypothesis about parental immune activation. An intriguing story about people who can't burp, and turn to the internet for answers. Turns out there's a surprising treatment to unlock their gas.

The Therapeutic Goods Administration recently approved the psychedelic compound psilocybin for treatment-resistant depression; and MDMA–or ecstasy–for treatment-resistant post-traumatic stress disorder. A group of researchers think this is premature. More people are tackling the bracing discomfort of ice bath sessions—for the touted health benefits ... but there are some serious risks, so pay attention to the instructions before hopping in. Chronic, non-cancer-related pain is hard to treat and so alternate medications—like antidepressants—are used because of their action on the brain. A group of researchers has compiled the available evidence on their efficacy.

Australians will pay a lot to relieve the pain of arthritis—sometimes opting for unproven therapies using stem cells. Why does this happen? Women are twice as likely as men to be diagnosed with Alzheimer's disease. Researchers have long looked for the reason why— it may be related to the amount of 'cognitive reserve' some groups have been able to accumulate. Researchers have found that a protein in the K'gari (Fraser Island) funnel web spider venom has the ability to stop heart cells dying. It could also help preserve organs prior to transplant. A genetic form of diabetes can occur later in life, and doesn't require insulin. A pilot project has looked at the benefits of early genetic testing for it.

The Strengthening Medicare Report was released recently, and the key recommendations include changes to the digital health environment; working to scope of practice; and modernising My Health Record. Psilocybin and MDMA are now approved as treatments for depression and MDMA—with caveats. And still need co-ordination between clinicians and manufacturers (the TGA has not approved or registered specific psilocybin or MDMA medications). A financial reward for obese people to achieve sustainable weight loss has proved successful—but the general health environment must also be considered. How to make healthy weight work for a whole population and working on how food is presented and for which particular age groups—so a healthy choice can be made

The prescription rate for medications to treat Attention Deficit Hyperactivity Disorder rose in recent years but was still below what's thought to be the extent of the condition. Organ donation is one of the great miracles of our time, but that's not to say it's easy. To be viable, a heart needs to be transplanted within four or five hours, and this is a huge logistical challenge for a country the size of Australia. The Garvan Institute has studied the combination of genetic profile alongside family history of people with cancers called sarcomas, and found genes to aid early diagnosis.

Sun Pharmaceuticals is a supplier of generic medications and they're in hot water about possible violations of the manufacturing process at their facility in Gujarat, India. Fasting diets like the 5:2 or the 16/8 have become very popular. While there's lots of evidence for the benefits of the 5:2 diet in animals, there's hasn't been much in humans. The results are not out from a trial of intermittent fasting in overweight men and women. One of the biggest puzzles for humans is the brain, or more precisely, the minds. It's a bit of a mystery but still possible to learn something about how to keep it in good order. Hosts: Dr Norman Swan and Tegan Taylor

Royals have a tendency to change the course of history — in life and in death.  From King George III's apparent madness, to Queen Victoria's genetic legacy, the Health Report takes a look back at the illnesses (and deaths) that have shaped the world. Note that the change of broadcast time mentioned at the end of the program refers to our live program on Mondays.

Mild Cognitive Impairment (MCI) affects 7 or 8 per cent of people in their 60s, and one in four people in their 80s. In an ageing population the number of those with mild cognitive impairment will increase. There's a new perspective on the cause and progress of Alzheimer's disease. Are we doing the right thing by removing accumulated amyloid protein from the brains of people with it? Some people experience a tingly feeling when they hear certain noises and this feeling might be a useful intervention for people with anxiety. Atrial fibrillation is a type of arrhythmia characterised by a rapid and irregular heartbeat. There is increasing evidence that relaxation methods like yoga and meditation can help manage the condition. Hosts: Dr Norman Swan Tegan Taylor

More than two decades ago a major milestone in cancer research was reached with the discovery of the BRCA1 and BRCA2 genes. Inherited mutations to these genes can dramatically increase the risk of developing breast and ovarian cancers. The discovery opened up new ways of knowing who is at risk of cancer, how to treat the cancer, and even how to prevent it happening in the first place. This moving feature describes what this genetic information means for families who have seen loved ones endure sometimes multiple cancers—and it explains the emerging frontier in medicine trying to change that. Guests: Michelle Brady Anna Murphy Dr Mark Pinese, Team Leader Personalised Medicine, Children’s Cancer Institute A/Prof Paul James, Clinical Geneticist and Director, Familial Cancer Centre, Peter MacCallum Cancer Centre and Royal Melbourne Hospital Dr Laura Forrest, Senior Research Fellow and Genetic Counsellor, Peter MacCallum Cancer Centre Host: Dr Norman Swan Interviewer and Producer: Sarah Sedghi

With COVID we've focused on vaccines and masks but there is more we can do, and the situation parallels a public health revolution from the mid-1800s. If you're a modern human you likely carry a bit of tech on you to track how physically active you are. But how can we be sure it's really promoting activity? Telomeres are small 'caps' on the ends of your chromosomes—the length of telomeres is seen as an indicator of how fast we age. How accurate could they be? Hosts: Tegan Taylor and Dr Norman Swan

It's expected now that on the whole we will live longer, but individuals want to know how to spend a longer life in good health—and to set a good foundation. This program was first heard on 25 April, 2022 Dr Norman Swan's book was published in July 2022. Guest: Prof Luigi Fontana Leonard P Ullman Chair in Translational Metabolic Health Director, Healthy Longevity Research and Clinical Program Charles Perkins Centre | Sydney Medical School (Central Clinical School) Faculty of Medicine and Health,  University of Sydney Host: Dr Norman Swan

A new study has found a genetic link between macular degeneration and Alzheimer's disease—with implications for drug development. The wellness space often refers to nicotinamide adenine dinucleotide—or NAD. It's found in products promoting longevity—so may give you pause for thought—but shows promising results for human eyesight. High blood pressure is one of the most toxic risk factors for heart attack, stroke, kidney damage, dementia, and probably premature ageing—so it's incredibly important to get blood pressure under control. Hosts: Dr Norman Swan and Tegan Taylor

Fish oil supplements—aka omega 3 fatty acids—are taken by some women during pregnancy. What are the benefits, and who gets them? Research into ageing has revealed a number of processes controlling its rate. Autophagy helps cells do a clean up. Researchers are wondering if it could be manipulated. Is it possible to say whether a pandemic is a natural spillover from an animal, or an accidental release from a lab? In her new book, Dark Winter, Professor Raina MacIntyre warns that scientists may not be the people to identify the source of pandemics—rather that Intelligence and law enforcement services could have a better toolkit.

The ABC’s Birth Project call out is discovering the good and bad of pregnancy and birth in Australia—one of the safest places in the world to give birth, but which sometimes fails women, their families, and clinicians. Parents-to-be now have access to simple blood tests that can indicate whether their baby might have a chromosome issue. But parents who want peace of mind or want to know the sex of their baby can feel blindsided when the result predicts high risk—or for something they didn't know they were being screened for. The Birth Project has shown us that the kind of care you might get if you're pregnant varies wildly across Australia. A national strategy around improving maternity care was launched in 2019.

With humans set to spend more time in spacer, one of the physical things to overcome will be gravity, and it's very important for how our bodies work. We hear frequent stories of mental health issues, but there is more investment in services, so are services effective or overwhelmed? An estimated 34,000 people in Australia have cerebral palsy. The cause can be a mystery but looking at a child's genes may supply information for parents and treatment teams.  Hosts: Dr Norman Swan Tegan Taylor

There's been talk of changing the packet size of paracetamol tablets, to reduce the self-harm of overdose—but it would be better to investigate and remedy why this harm occurs. The idea that society—as well as an individual—is responsible for this 'health literacy' is central to a new World Health Organisation report. Results of a randomised trial in people with low back pain who used a spinal cord stimulator were published recently, and the researchers are surprised by what they found. Hosts: Dr Norman Swan and Tegan Taylor

How analysts are making health data safer | Linked health data can see the bigger picture of healthcare use  | Clinical trials need more clarity on the kind of harms incurred | Donating mitochondria may mitigate the risk of some genetic disorders—but it's not a given.

The ABC series Magda's Big National Health Check us an immersive and personal journey about health in Australia today. It''s hosted by Magda Szubanski, who wants to know why Australia has a high level of chronic illness—and what to do about it. The latest statistics on causes of deaths in Australia show that deaths caused by alcohol rose by 6% last year—it's avoidable and advocates for greater alcohol control measures have been warning for years that there are not enough of them. Hosts: Dr Norman Swan and Tegan Taylor

Severe chronic traumatic encephalopathy (CTE) can be defined in pathology, yet only be diagnosed after someone has died and their brain examined. The Victorian state election is on 26th November and hospitals feature in political healthcare promises. Labor anticipates spending more than $6 billion on new hospitals and upgrading existing ones. Guest: Assoc Prof Michael Buckland Head of Dept of Neuropathology Royal Prince Alfred Hospital and Director, Australian Sports Brain Bank

There's a new perspective on how we think about the cause and progress of Alzheimer's disease. Are we actually doing the right thing by removing accumulated amyloid protein from the brain of people with it? Health practitioners are often still operating under the assumption that obesity is an individual's responsibility, even though science now tells us otherwise. It makes intuitive sense that if you screen people for disease the outcome will be good - because you get on top of the problem. But how far should you go.

The debate may be over about robotic surgery for men with prostate cancer—but can hospitals afford the robots? How do you know if memory lapses are a part of slowing down—or an early sign of dementia? The psychology of moving more—and eating better. An Australian researcher in women and cancer has died .

Bringing clarity to health and medical issues from social, scientific and political points of view.

Bringing clarity to health and medical issues from social, scientific and political points of view.

From King George III's apparent madness, to Queen Victoria's genetic legacy, the Health Report takes a look back at the illnesses (and deaths) that have shaped the world.

Vital health and medical news.

Vital health and medical news.

Vital health and medical news.

Exploring how changing your diet—or even your eating schedule—can improve your long-term health outcomes.

Vital health and medical news.

An option for cervical cancer screening could be a game-changer and miscarriages or stillbirths may bring an increased risk of stroke

With COVID there are more protective measures to take—and there's a historical parallel | The results of a trial of vitamin D supplementation find no evidence to support vitamin D supplements | Shingles can be a painful disease and those over 70 can have a free vaccination, but not the costly and most effective one.

The amount of money to spend on health care in the last year of someone's life is debatable. | The vital eligibility criterion for voluntary assisted dying in Australia is a problematic issue for doctors. | For a heart attack you want the best care possible—but where you live can affect limit that. Climate change is becoming more obvious—it now includes a noticeable mental health aspect.

Some immunologists are concerned that COVID-19 is not travelling as expected. An internationally respected immunologist had four doses of COVID vaccine but now recovering from heart failure after getting the virus. There are still community questions about the value of getting a fourth vaccine dose—we asked a vaccine development expert to explain why you should. Fitness and living longer are more than just how much you eat and how much you exercise?

In 2009 Australia launched a National Preventive Health Strategy with the aim of being the healthiest country in the world by 2020—where we're at with it now. The Australian Commission on Safety and Quality in Healthcare has created a national clinical care standard for diagnosis and treatment. Many people are told to take a vitamin D supplement, especially in winter when there's less sunshine, but you can have too much of it.

Australia has many stories from people who say they have long COVID but who are unable to access help | Updated versions of coronavirus vaccines targeting the Omicron variant have been announced, yet the virus still mutates | People with Type 1 diabetes need to monitor their blood glucose but automatic systems are being trialled to assist them | A study on the behaviour of teens undertaken during the pandemic identified some of the particular health risks for this group.

What an Australian Centre for Disease Control might aim to be; An Indigenous perspective and research to engage culture for protection against cardiovascular disease and stroke; Research on links between mental health and mortality concludes that both mental and physical health can be adversely impacted.

There may be a link between what you eat and your mental health—also, avoiding overtreatment for breast cancer; predicting your risk of osteoarthritis; and whether mammogram results should inform women about breast density.

The cancer risks that run through generations of families—and the growing frontier in medicine trying to change that.