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What's That Rash?

What's That Rash?

ABC Australia

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2049 - NMN, NAD+ and other acronyms of anti-aging
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  • 2049 - NMN, NAD+ and other acronyms of anti-aging

    As we age, levels of a vital molecule called nicotinamide adenine dinucleotide (NAD+) decline. Could reversing this be the key to eternal youth? There’s huge interest in NAD-boosting supplements like nicotinamide mononucleotide (NMN). But is there good evidence that they can help us live longer, healthier? Norman and Tegan unpack how NAD+ became the focus of anti-aging proponents. This episode first aired on November 4, 2024. References: NAD+ metabolism and its roles in cellular processes during ageing NAD+ in Brain Aging and Neurodegenerative Disorders What is really known about the effects of nicotinamide riboside supplementation in humans Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions The use of a systems approach to increase NAD+ in human participants Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging

    Wed, 30 Sep 2026 - 16min
  • 2048 - All our (travel) bubbles are bursting. What comes next?

    After nearly two years of constant internal border changes, by the end of this week large parts of Australia will once again be open for domestic travel. South Australia opened a few weeks ago, Queensland opened yesterday and Tasmania is due to open tomorrow. Western Australia has also finally given a date and will reopen on the 5th of February next year. So with state and territory bubbles bursting all over the place, what might come next for people who live there? Also on today's show: * How is decoupling going? * Fourth dose anyone? * Pregnancy and booster shots

    Tue, 14 Dec 2021 - 10min
  • 2047 - Why is the Moderna booster a half shot?

    Australia now has two different booster options to choose from when the inevitable time comes for the third dose of coronavirus vaccine. Moderna was approved by the country's vaccine expert group ATAGI over the weekend. We'll also be able to get the booster a month earlier, with the Government announcing a shorter period due to the threat of waning immunity and new variants. So if Moderna is a choice, should you take it over Pfizer? Does it even matter? And why is the Moderna booster only a half shot? Also on today's show: * A preprint study has found that Astra seems to wane faster than other vaccines, leaving no protective effect against symptomatic disease from Omicron 15 weeks after the second dose. What could this mean for the country's booster campaign?

    Mon, 13 Dec 2021 - 10min
  • 2046 - All roads lead to third doses

    As the data from initial studies into how Omicron evades our immunity continue to flow in, it's becoming more and more likely that a third dose - or booster - is going to be essential. Several more studies have been released, all showing large falls in immunity to the Omicron variant. One thing that the studies imply though is that there are much higher antibody levels in people who have either been infected, or received a third dose. So how much will third doses be needed to combat Omicron? Also on today's show: Quick Fire Friday! (booster edition)

    Fri, 10 Dec 2021 - 10min
  • 2045 - Omicron evades vaccines, but not all is lost

    One of the first studies into Omicron and immunity has reported back and it's not super great news: there's significant evasion of antibodies produced by the Pfizer vaccine. But not all is lost. The study says that the Omicron variant uses the same way of getting into our cells, meaning our existing tools and techniques should be relatively easy to change so they work better. The study is not yet published, and is a very small sample size so it's worth keeping in mind that this is still a very new area of science and is subject to change. Nonetheless, as today's Coronacast explains, it does give us a glimpse of what is likely to come. Also on today's show: * Could a mozzie vaccinate someone by biting a vaxed person and then an unvaxed person? * Your booster experiences

    Thu, 09 Dec 2021 - 11min
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